{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:43:16Z","timestamp":1783701796480,"version":"3.55.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Health Qual Life Outcomes"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>Quality of Life (QoL) is impaired in cancer, and the elderly are particularly vulnerable to malnutrition. A diagnosis of cancer in elderly patients further exacerbates risks of negative health outcomes. Here we investigated associations between QoL and nutritional status in a sample population of mostly socially deprived elderly cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>432 cancer patients were recruited for this cross-sectional study at point of admission to a tertiary referral hospital for cancer treatment. Patient-generated subjective global assessment (PG-SGA) assessed nutritional status. Functional assessment of cancer therapy- general (FACT-G) quantified QoL. Relationship between PG-SGA and QoL was assessed by Spearman correlation. PG-SGA outcomes were compared against FACT-G scores employing Mann\u2013Whitney test. Bivariate Linear Regression Model was employed to investigate influences of sociodemographic, clinical and nutritional status upon QoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      37.5% of participants were malnourished or at risk. 39% were illiterate and 54.6% had family income lower than minimum wage. Malnourished patients showed lower FACT-G scores (76.8 vs. 84.7;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000). Poor nutritional diagnosis was inversely correlated with all QoL domains. Bivariate regression analysis showed that lower PG-SGA scores (\u03b2o\u2009=\u2009\u2009\u2212\u20091.00;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000) contributed to FACT-G score deterioration, the male gender showed better QoL scores, and other clinical and sociodemographic variables did not show relationship.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Poorer nutritional status was significantly associated with worsened physical, social, emotional and functional well-being QoL domains in elderly cancer patients. Poorer nutritional status is an independent risk factor for worsened QoL. Future policies aimed at particularly vulnerable populations may improve QoL and health outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12955-021-01735-7","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T07:03:01Z","timestamp":1615964581000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["A poorer nutritional status impacts quality of life in a sample population of elderly cancer patients"],"prefix":"10.1186","volume":"19","author":[{"given":"Tatiane Correia","family":"Rios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucivalda Pereira Magalh\u00e3es","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L\u00facia Varj\u00e3o","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona Souza","family":"da Silva Baqueiro Boulhosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Karla Carneiro","family":"Roriz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilian Barbosa","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9456-8558","authenticated-orcid":false,"given":"Allain Amador","family":"Bueno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"1735_CR1","first-page":"147","volume":"117","author":"NA Berger","year":"2006","unstructured":"Berger NA, Savvides P, Koroukian SM, et al. Cancer in the elderly. Trans Am Clin Climatol Assoc. 2006;117:147\u201356.","journal-title":"Trans Am Clin Climatol Assoc"},{"issue":"4","key":"1735_CR2","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1590\/S1415-52732004000400010","volume":"17","author":"LR Sampaio","year":"2004","unstructured":"Sampaio LR. Avalia\u00e7\u00e3o nutricional e envelhecimento. Rev Nutr Camp. 2004;17(4):507\u201314. https:\/\/doi.org\/10.1590\/S1415-52732004000400010.","journal-title":"Rev Nutr Camp"},{"issue":"5\u20136","key":"1735_CR3","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/BF03325237","volume":"23","author":"M Deschodt","year":"2011","unstructured":"Deschodt M, Wellens NI, Braes T, et al. Prediction of functional decline in older hospitalized patients: a comparative multicenter study of three screening tools. Aging Clin Exp Res. 2011;23(5\u20136):421\u20136. https:\/\/doi.org\/10.1007\/BF03325237.","journal-title":"Aging Clin Exp Res"},{"issue":"4","key":"1735_CR4","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1590\/S0034-71672011000400010","volume":"64","author":"AA Peterson","year":"2011","unstructured":"Peterson AA, Carvalho EC. Comunica\u00e7\u00e3o terap\u00eautica na Enfermagem: dificuldades para o cuidar de idosos com c\u00e2ncer. Rev Bras Enferm. 2011;64(4):692\u20137. https:\/\/doi.org\/10.1590\/S0034-71672011000400010.","journal-title":"Rev Bras Enferm"},{"issue":"4","key":"1735_CR5","doi-asserted-by":"publisher","first-page":"660","DOI":"10.4025\/cienccuidsaude.v9i4.7785","volume":"9","author":"LC Soares","year":"2010","unstructured":"Soares LC, Santana MG, Muniz RM. O Fen\u00f4meno do c\u00e2ncer na vida de idosos. Cienc Cuid Saude. 2010;9(4):660\u20137. https:\/\/doi.org\/10.4025\/cienccuidsaude.v9i4.7785.","journal-title":"Cienc Cuid Saude"},{"issue":"7","key":"1735_CR6","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1093\/jnci\/81.7.485","volume":"81","author":"CM Moinpour","year":"1989","unstructured":"Moinpour CM, Feigl P, Metch B, Hayden KA, Meyskens FL Jr, Crowley J. Quality of life end points in cancer clinical trials: review and recommendations. J Natl Cancer Inst. 1989;81(7):485\u201395. https:\/\/doi.org\/10.1093\/jnci\/81.7.485.","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"1735_CR7","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1038\/s41430-020-0629-0","volume":"74","author":"AF Bullock","year":"2020","unstructured":"Bullock AF, Greenley SL, McKenzie GAG, Paton LW, Johnson MJ. Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis. Eur J Clin Nutr. 2020;74(11):1519\u201335. https:\/\/doi.org\/10.1038\/s41430-020-0629-0.","journal-title":"Eur J Clin Nutr"},{"issue":"7\u20138","key":"1735_CR8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/s0899-9007(01)00573-1","volume":"17","author":"DL Waitzberg","year":"2001","unstructured":"Waitzberg DL, Caiffa WT, Correia MI. Hospital malnutrition: the Brazilian national survey (IBRANUTRI): a study of 4000 patients. Nutrition. 2001;17(7\u20138):573\u201380. https:\/\/doi.org\/10.1016\/s0899-9007(01)00573-1.","journal-title":"Nutrition"},{"issue":"1","key":"1735_CR9","first-page":"60","volume":"5","author":"MSP Fidelix","year":"2013","unstructured":"Fidelix MSP, Santana AFF, Gomes JR. Prevalence of hospital malnutrition in elderly. RASBRAN Rev Assoc Bras Nutr. 2013;5(1):60\u20138.","journal-title":"RASBRAN Rev Assoc Bras Nutr"},{"issue":"1 Suppl","key":"1735_CR10","doi-asserted-by":"publisher","first-page":"S15","DOI":"10.1016\/0899-9007(96)90011-8","volume":"12","author":"FD Ottery","year":"1996","unstructured":"Ottery FD. Definition of standardized nutritional assessment and interventional pathways in oncology. Nutrition. 1996;12(1 Suppl):S15\u20139. https:\/\/doi.org\/10.1016\/0899-9007(96)90011-8.","journal-title":"Nutrition"},{"issue":"2","key":"1735_CR11","first-page":"102","volume":"25","author":"MC Gonzalez","year":"2010","unstructured":"Gonzalez MC, Borges LR, Silveira DH, Assun\u00e7\u00e3o MCF, Orlandi SP. Valida\u00e7\u00e3o da vers\u00e3o em portugu\u00eas da avalia\u00e7\u00e3o subjetiva global produzida pelo paciente. Rev Bras Nutr Clin. 2010;25(2):102\u20138.","journal-title":"Rev Bras Nutr Clin"},{"issue":"1","key":"1735_CR12","doi-asserted-by":"publisher","first-page":"384","DOI":"10.3305\/nh.2015.31.1.7543","volume":"31","author":"CA Santos","year":"2015","unstructured":"Santos CA, Rosa COB, Ribeiro AQ, Ribeiro RCL. Patient-generated subjective global assessment and classic anthropometry: comparison between the methods in detection of malnutrition among elderly with cancer. Nutr Hosp. 2015;31(1):384\u201392. https:\/\/doi.org\/10.3305\/nh.2015.31.1.7543.","journal-title":"Nutr Hosp"},{"issue":"11","key":"1735_CR13","doi-asserted-by":"publisher","first-page":"2225","DOI":"10.2147\/CMAR.S193567","volume":"19","author":"T Ge","year":"2019","unstructured":"Ge T, Lin T, Yang J, Wang M. Nutritional status and related factors of patients with advanced lung cancer in northern China: a retrospective study. Cancer Manag Res. 2019;19(11):2225\u201331. https:\/\/doi.org\/10.2147\/CMAR.S193567.","journal-title":"Cancer Manag Res"},{"issue":"9","key":"1735_CR14","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1016\/j.hpb.2019.01.003","volume":"21","author":"TH Huang","year":"2019","unstructured":"Huang TH, Hseih CC, Kuo LM, Chang CC, Chen CH, Chi CC, Liu CH. Malnutrition associated with an increased risk of postoperative complications following hepatectomy in patients with hepatocellular carcinoma. HPB (Oxford). 2019;21(9):1150\u20135. https:\/\/doi.org\/10.1016\/j.hpb.2019.01.003.","journal-title":"HPB (Oxford)"},{"key":"1735_CR15","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/1477-7525-1-79","volume":"1","author":"K Webster","year":"2003","unstructured":"Webster K, Cella D, Yost K. The functional assessment of chronic illness therapy (FACIT) measurement system: properties, applications, and interpretation. Health Qual Life Outcomes. 2003;1:79. https:\/\/doi.org\/10.1186\/1477-7525-1-79.","journal-title":"Health Qual Life Outcomes"},{"key":"1735_CR16","doi-asserted-by":"publisher","DOI":"10.12707\/RIII1041","author":"FMP Pereira","year":"2011","unstructured":"Pereira FMP, Santos CSVB. Estudo de adapta\u00e7\u00e3o cultural e valida\u00e7\u00e3o da functional assessment of cancer therapy-general em cuidados paliativos. Rev Enferm Ref. 2011. https:\/\/doi.org\/10.12707\/RIII1041.","journal-title":"Rev Enferm Ref"},{"key":"1735_CR17","volume-title":"Delineando a pesquisa cl\u00ednica: uma abordagem epidemiol\u00f3gica","author":"SB Hulley","year":"2003","unstructured":"Hulley SB, Cummings SR, Browner WS, Grady D, Hearst N, Newman TB. Delineando a pesquisa cl\u00ednica: uma abordagem epidemiol\u00f3gica. 2a ed. Porto Alegre: Editora Artmed; 2003.","edition":"2a"},{"issue":"3","key":"1735_CR18","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.clnu.2007.01.005","volume":"26","author":"MM Mar\u00edn Caro","year":"2007","unstructured":"Mar\u00edn Caro MM, Laviano A, Pichard C. Nutritional intervention and quality of life in adult oncology patients. Clin Nutr. 2007;26(3):289\u2013301. https:\/\/doi.org\/10.1016\/j.clnu.2007.01.005.","journal-title":"Clin Nutr"},{"issue":"4","key":"1735_CR19","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1002\/cncr.11110","volume":"97","author":"H Chen","year":"2003","unstructured":"Chen H, Cantor A, Meyer J, et al. Can older cancer patients tolerate chemotherapy? A prospective pilot study. Cancer. 2003;97(4):1107\u201314. https:\/\/doi.org\/10.1002\/cncr.11110.","journal-title":"Cancer"},{"issue":"2","key":"1735_CR20","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/sj.ejcn.1601552","volume":"57","author":"E Isenring","year":"2003","unstructured":"Isenring E, Bauer J, Capra S. The scored patient-generated subjective global assessment (PG-SGA) and its association with quality of life in ambulatory patients receiving radiotherapy. Eur J Clin Nutr. 2003;57(2):305\u20139. https:\/\/doi.org\/10.1038\/sj.ejcn.1601552.","journal-title":"Eur J Clin Nutr"},{"issue":"11","key":"1735_CR21","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1007\/s00520-014-2281-5","volume":"22","author":"R Barrios","year":"2014","unstructured":"Barrios R, Tsakos G, Garc\u00eda-Medina B, Mart\u00ednez-Lara I, Bravo M. Oral health-related quality of life and malnutrition in patients treated for oral cancer. Support Care Cancer. 2014;22(11):2927\u201333. https:\/\/doi.org\/10.1007\/s00520-014-2281-5.","journal-title":"Support Care Cancer"},{"key":"1735_CR22","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/1471-2407-10-232","volume":"10","author":"B Laky","year":"2010","unstructured":"Laky B, Janda M, Kondalsamy-Chennakesavan S, Cleghorn G, Obermair A. Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study. BMC Cancer. 2010;10:232. https:\/\/doi.org\/10.1186\/1471-2407-10-232.","journal-title":"BMC Cancer"},{"issue":"2","key":"1735_CR23","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1503\/cjs.025411","volume":"56","author":"C Zacharias","year":"2013","unstructured":"Zacharias C, Zacharias T. Outcome 1 year after digestive surgery in malnourished, elderly patients, with an emphasis on quality of life analysis. Can J Surg. 2013;56(2):128\u201334. https:\/\/doi.org\/10.1503\/cjs.025411.","journal-title":"Can J Surg"},{"issue":"4","key":"1735_CR24","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s00520-009-0681-8","volume":"18","author":"G Capuano","year":"2010","unstructured":"Capuano G, Gentile PC, Bianciardi F, Tosti M, Palladino A, Di Palma M. Prevalence and influence of malnutrition on quality of life and performance status in patients with locally advanced head and neck cancer before treatment. Support Care Cancer. 2010;18(4):433\u20137. https:\/\/doi.org\/10.1007\/s00520-009-0681-8.","journal-title":"Support Care Cancer"},{"issue":"3","key":"1735_CR25","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1038\/sj.bjc.6600466","volume":"87","author":"HR Scott","year":"2002","unstructured":"Scott HR, McMillan DC, Forrest LM, Brown DJ, McArdle CS, Milroy R. The systemic inflammatory response, weight loss, performance status and survival in patients with inoperable non-small cell lung cancer. Br J Cancer. 2002;87(3):264\u20137. https:\/\/doi.org\/10.1038\/sj.bjc.6600466.","journal-title":"Br J Cancer"},{"issue":"21","key":"1735_CR26","doi-asserted-by":"publisher","first-page":"6379","DOI":"10.1158\/1078-0432.CCR-07-1147","volume":"13","author":"M Fouladiun","year":"2007","unstructured":"Fouladiun M, K\u00f6rner U, Gunnebo L, Sixt-Ammilon P, Bosaeus I, Lundholm K. Daily physical-rest activities in relation to nutritional state, metabolism, and quality of life in cancer patients with progressive cachexia. Clin Cancer Res. 2007;13(21):6379\u201385. https:\/\/doi.org\/10.1158\/1078-0432.CCR-07-1147.","journal-title":"Clin Cancer Res"},{"issue":"8","key":"1735_CR27","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1093\/jnci\/djj130","volume":"98","author":"C Sweeney","year":"2006","unstructured":"Sweeney C, Schmitz KH, Lazovich D, Virnig BA, Wallace RB, Folsom AR. Functional limitations in elderly female cancer survivors. J Natl Cancer Inst. 2006;98(8):521\u20139. https:\/\/doi.org\/10.1093\/jnci\/djj130.","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"1735_CR28","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/ageing\/afy169","volume":"48","author":"AJ Cruz-Jentoft","year":"2019","unstructured":"Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis [published correction appears in Age Ageing. 2019 Jul 1;48(4):601]. Age Ageing. 2019;48(1):16\u201331. https:\/\/doi.org\/10.1093\/ageing\/afy169.","journal-title":"Age Ageing"},{"issue":"3","key":"1735_CR29","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1007\/s10120-015-0546-4","volume":"19","author":"Y Fukuda","year":"2016","unstructured":"Fukuda Y, Yamamoto K, Hirao M, et al. Sarcopenia is associated with severe postoperative complications in elderly gastric cancer patients undergoing gastrectomy. Gastric Cancer. 2016;19(3):986\u201393. https:\/\/doi.org\/10.1007\/s10120-015-0546-4.","journal-title":"Gastric Cancer"},{"issue":"6","key":"1735_CR30","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1038\/bjc.2012.350","volume":"107","author":"JR Lieffers","year":"2012","unstructured":"Lieffers JR, Bathe OF, Fassbender K, Winget M, Baracos VE. Sarcopenia is associated with postoperative infection and delayed recovery from colorectal cancer resection surgery. Br J Cancer. 2012;107(6):931\u20136. https:\/\/doi.org\/10.1038\/bjc.2012.350.","journal-title":"Br J Cancer"},{"issue":"4","key":"1735_CR31","first-page":"255","volume":"26","author":"RC Fortes","year":"2011","unstructured":"Fortes RC, Waitzberg DL. Efeitos da imunonutri\u00e7\u00e3o enteral em pacientes oncol\u00f3gicos submetidos \u00e0 cirurgia do trato gastrintestinal. Rev Bras Nutr Clin. 2011;26(4):255\u201363.","journal-title":"Rev Bras Nutr Clin"},{"issue":"1","key":"1735_CR32","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/pon.4090","volume":"26","author":"S Duc","year":"2017","unstructured":"Duc S, Rainfray M, Soubeyran P, et al. Predictive factors of depressive symptoms of elderly patients with cancer receiving first-line chemotherapy. Psychooncology. 2017;26(1):15\u201321. https:\/\/doi.org\/10.1002\/pon.4090.","journal-title":"Psychooncology"},{"issue":"8","key":"1735_CR33","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1111\/ggi.12378","volume":"15","author":"H Yoon","year":"2015","unstructured":"Yoon H, Kim Y, Lim YO, Lee HJ, Choi K. Factors affecting quality of life of older adults with cancer in Korea. Geriatr Gerontol Int. 2015;15(8):983\u201390. https:\/\/doi.org\/10.1111\/ggi.12378.","journal-title":"Geriatr Gerontol Int"},{"issue":"6","key":"1735_CR34","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/j.1464-410X.2007.07353.x","volume":"101","author":"N Sadetsky","year":"2008","unstructured":"Sadetsky N, Lubeck DP, Pasta DJ, Latini DM, DuChane J, Carroll PR. Insurance and quality of life in men with prostate cancer: data from the cancer of the prostate strategic urological research endeavor. BJU Int. 2008;101(6):691\u20137. https:\/\/doi.org\/10.1111\/j.1464-410X.2007.07353.x.","journal-title":"BJU Int"},{"issue":"6","key":"1735_CR35","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.eururo.2017.06.035","volume":"72","author":"M Lardas","year":"2017","unstructured":"Lardas M, Liew M, van den Bergh RC, et al. Quality of life outcomes after primary treatment for clinically localised prostate cancer: a systematic review. Eur Urol. 2017;72(6):869\u201385. https:\/\/doi.org\/10.1016\/j.eururo.2017.06.035.","journal-title":"Eur Urol"},{"key":"1735_CR36","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1146\/annurev.pu.14.050193.002035","volume":"14","author":"JF Kerner","year":"1993","unstructured":"Kerner JF, Dusenbury L, Mandelblatt JS. Poverty and cultural diversity: challenges for health promotion among the medically underserved. Annu Rev Public Health. 1993;14:355\u201377. https:\/\/doi.org\/10.1146\/annurev.pu.14.050193.002035.","journal-title":"Annu Rev Public Health"},{"key":"1735_CR37","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1186\/1471-2407-14-427","volume":"14","author":"L Brugel","year":"2014","unstructured":"Brugel L, Laurent M, Caillet P, et al. Impact of comprehensive geriatric assessment on survival, function, and nutritional status in elderly patients with head and neck cancer: protocol for a multicentre randomised controlled trial (EGeSOR). BMC Cancer. 2014;14:427. https:\/\/doi.org\/10.1186\/1471-2407-14-427.","journal-title":"BMC Cancer"}],"container-title":["Health and Quality of Life Outcomes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12955-021-01735-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12955-021-01735-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12955-021-01735-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T07:05:26Z","timestamp":1615964726000},"score":1,"resource":{"primary":{"URL":"https:\/\/hqlo.biomedcentral.com\/articles\/10.1186\/s12955-021-01735-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,17]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1735"],"URL":"https:\/\/doi.org\/10.1186\/s12955-021-01735-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-51751\/v1","asserted-by":"object"}]},"ISSN":["1477-7525"],"issn-type":[{"value":"1477-7525","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,17]]},"assertion":[{"value":"5 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study received ethical approval from the Research Ethics Committee of the School of Nutrition, Federal University of Bahia (187,441\/12) and from the Research Ethics Committee of the Hospital Aristides Maltez (00,913\/12), Salvador, Brazil. All patients were explained the aims and objectives of the study, and those who agreed to participate signed the \u2018Free and Informed Consent Form\u2019, which included a clause on \u2018Consent to Publish\u2019.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Consent to participate & Consent for publication"}},{"value":"The authors declare that this research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"90"}}