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The Perceived Risk of HIV Scale is an 8-item measure that assesses how people think and feel about their risk of infection. We set out to perform a cross-cultural adaptation of the scale to Brazilian Portuguese among key populations (gay, bisexual and other men who have sex with men and transgender\/non-binary) and other populations (cisgender heterosexual men and cisgender women).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Methodological study with cross-sectional design conducted online during October\/2019 (key populations [sample 1] and other populations) and February\u2013March\/2020 (key populations not on pre-exposure prophylaxis [sample 2]). Cross-cultural adaptation of the Perceived Risk of HIV Scale followed Beaton et al. 2000 guidelines and included confirmatory factor analysis, differential item functioning (DIF) using the Multiple-Indicator Multiple-Cause model, and concurrent validity to verify if younger individuals, those ever testing for HIV, and engaging in high-risk behaviors had higher scores on the scale.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>4342 participants from key populations (sample 1\u2009=\u2009235; sample 2\u2009=\u20094107) and 155 participants from other populations completed the measure. We confirmed the single-factor structure of the original measure (fit indices for sample 1 plus other populations: CFI\u2009=\u20090.98, TLI\u2009=\u20090.98, RMSEA\u2009=\u20090.07; sample 2 plus other populations: CFI\u2009=\u20090.97, TLI\u2009=\u20090.95, RMSEA\u2009=\u20090.09). For the comparisons between key populations and other populations, three items (item 2: \u201cI worry about getting infected with HIV\u201d, item 4: \u201cI am sure I will not get infected with HIV\u201d, and item 8: \u201cGetting HIV is something I have\u201d) exhibited statistically significant DIF. Items 2 and 8 were endorsed at higher levels by key populations and item 4 by other populations. However, the effect of DIF on overall scores was negligible (0.10 and 0.02 standard deviations for the models with other populations plus sample 1 and 2, respectively). Those ever testing for HIV scored higher than those who never tested (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001); among key populations, those engaging in high-risk behaviors scored higher than those reporting low-risk.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The Perceived Risk of HIV Scale can be used among key populations and other populations from Brazil.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12955-021-01760-6","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T11:03:31Z","timestamp":1617966211000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Cross-cultural adaptation of the Perceived Risk of HIV Scale in Brazilian Portuguese"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2557-601X","authenticated-orcid":false,"given":"Thiago S.","family":"Torres","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula M.","family":"Luz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana M. 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J2\u2014indiv\u00edduos que possuem telefone celular 2019 [Internet]; 2020. https:\/\/cetic.br\/pt\/tics\/domicilios\/2019\/individuos\/J2\/."}],"container-title":["Health and Quality of Life Outcomes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12955-021-01760-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12955-021-01760-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12955-021-01760-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T11:12:58Z","timestamp":1617966778000},"score":1,"resource":{"primary":{"URL":"https:\/\/hqlo.biomedcentral.com\/articles\/10.1186\/s12955-021-01760-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,9]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1760"],"URL":"https:\/\/doi.org\/10.1186\/s12955-021-01760-6","relation":{},"ISSN":["1477-7525"],"issn-type":[{"value":"1477-7525","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,9]]},"assertion":[{"value":"15 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This analysis is part of a larger project to study GBM\u2019s behavior, risk perception and knowledge of HIV transmission, prevention and treatment in Brazil, which was approved by INI Evandro Chagas-FIOCRUZ institutional review board (#CAAE 01777918.0.0000.5262) in accordance with all applicable regulations. All study participants provided electronic informed consent before initiating the survey. Informed consent contained information on the length of time of the survey, data stored and investigator name and contact. No incentives were provided.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors fulfill the criteria for authorship, and have read and approved the final version of this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"117"}}