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These patients received treatment in our hospital between May 2017 and May 2020. The general information, characteristics of the color Doppler echocardiography, molybdenum, conventional pathology, and molecular pathology of the patients were collected. Factors influencing sentinel lymph node metastasis in breast cancer patients were retrospectively analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In this study, age, tumor diameter, BI-RADS category, pathology type, expression profiles of CK5\/6, EGFR, and CK19, and TP53 and BRAC1\/2 mutations were independent risk factors for sentinel lymph node metastasis in breast cancer (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). The number and locations of tumors, quadrant of tumors, regularity of tumor margins, presence of blood flow signals, presence of posterior echo attenuation, presence of calcification, histological grade, molecular typing, and mutations of BRAF, ATM, and PALB2 were irrelevant factors (\n                      <jats:italic>P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In conclusion, age, tumor diameter, BI-RADS category, invasive type, expression of CK5\/6, EGFR, and CK19, and mutations in TP53 and BRAC1\/2 were positively correlated with sentinel lymph node metastasis. These independent risk factors should be given more attention in clinical studies to strengthen the management and control of sentinel lymph node metastasis in high-risk breast cancer and support early chemotherapy or targeted therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12957-022-02531-3","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T21:02:43Z","timestamp":1646686963000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Analysis on factors behind sentinel lymph node metastasis in breast cancer by color ultrasonography, molybdenum target, and pathological detection"],"prefix":"10.1186","volume":"20","author":[{"given":"Aibibai","family":"Yiming","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhetaer","family":"Wubulikasimu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuermaimaiti","family":"Yusuying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"2531_CR1","doi-asserted-by":"crossref","unstructured":"Gyawali B, Kesselheim AS. 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