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Among the 11 patients, 8(72.7%) were males, and 3(27.3%) were females, with an average age of 48.1\u00a0years. All patients underwent emergency surgery. A total of 9 patients underwent open appendectomy, including 1 patient who underwent second-stage simple right hemicolectomy after an appendectomy, and two who underwent laparoscopic appendectomy. All 11 patients were followed up for a period of 1 to 17\u00a0years. All patients survived without any indication of tumor recurrence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Appendiceal neuroendocrine neoplasms are low-grade malignant tumors originating from neuroendocrine cells. They are rarely seen in clinical practice and are often treated based on acute and chronic appendicitis symptoms. These tumors are challenging to diagnose before surgery due to the lack of specificity in clinical manifestations and auxiliary examinations. The diagnosis generally depends on postoperative pathology and immunohistochemistry. Despite the diagnostic challenges, these tumors have a favorable prognosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12957-023-03025-6","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:27:23Z","timestamp":1684294043000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Analysis of surgical treatment of appendix neuroendocrine neoplasms\u201417\u00a0years of single-center experience"],"prefix":"10.1186","volume":"21","author":[{"given":"He-wei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-yang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-cong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,17]]},"reference":[{"key":"3025_CR1","first-page":"510","volume":"25","author":"B Barut","year":"2019","unstructured":"Barut B, G\u00f6n\u00fclta\u015f F. 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The ethics committee of Wenzhou Central Hospital waived the need for Informed Consent due to the retrospective nature of the study. All procedures were carried out in accordance with the Helsinki Declaration. All methods were carried out in accordance with relevant guidelines and regulations in the declaration.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"150"}}