{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:57:53Z","timestamp":1792803473244,"version":"4.5.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Maxillary sinus squamous cell carcinoma (MS-SCC) is an infrequent malignancy, and determining the optimal neck management for patients with cT3\/4N0 MS-SCC remains a topic of ongoing debate. The purpose of this study was to compare the prognoses and quality of life outcomes of patients who underwent either elective neck dissection (END) or elective neck irradiation (ENI) for cT3\/4N0 MS-SCC.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this retrospective study, we enrolled patients with surgically treated cT3\/4N0 MS-SCC, and the impact of different neck management strategies on regional control and disease-specific survival was compared using propensity score matching. The effect of surgical intervention on quality of life was evaluated using the Mann-Whitney U test.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of the 120 patients included, 36 underwent END. After propensity score matching, our analysis indicated that END did not lead to superior outcomes than ENI, as demonstrated by comparable rates of regional control (<jats:italic>p<\/jats:italic>\u2009=\u20090.990) and disease-specific survival (<jats:italic>p<\/jats:italic>\u2009=\u20090.999). However, in the 70 returned questionnaires, patients who underwent END reported higher scores in the domains of appearance, chewing, and speech than did patients who underwent ENI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our findings suggest that while END and ENI contribute to similar prognoses, END yields superior functional outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12957-024-03368-8","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:43:03Z","timestamp":1713249783000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Elective neck dissection versus elective neck irradiation in cT3\/4N0 maxillary sinus squamous cell carcinoma: a propensity score matching analysis"],"prefix":"10.1186","volume":"22","author":[{"given":"Min","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hefeng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihong","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunyu","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"3368_CR1","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/hed.27512","volume":"46","author":"EJ Patel","year":"2024","unstructured":"Patel EJ, Strohl MP, Yom SS, El-Sayed I. Elective management of the N0 neck in maxillary sinus squamous cell carcinoma. Head Neck. 2024;46:171\u20136.","journal-title":"Head Neck"},{"key":"3368_CR2","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1002\/hed.25143","volume":"40","author":"JK Byrd","year":"2018","unstructured":"Byrd JK, Clair JM, El-Sayed IAHNS, Series. Do you know your guidelines? Principles for treatment of cancer of the paranasal sinuses: a review of the National Comprehensive Cancer Network guidelines. Head Neck. 2018;40:1889\u201396.","journal-title":"Head Neck"},{"key":"3368_CR3","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.1245\/s10434-014-3544-6","volume":"21","author":"A Homma","year":"2014","unstructured":"Homma A, Hayashi R, Matsuura K, Kato K, Kawabata K, Monden N, Hasegawa Y, Onitsuka T, Fujimoto Y, Iwae S, Okami K, Matsuzuka T, Yoshino K, Nibu K, Kato T, Nishino H, Asakage T, Ota I, Kitamura M, Kubota A, Ueda T, Ikebuchi K, Watanabe A, Fujii M. Lymph node metastasis in t4 maxillary sinus squamous cell carcinoma: incidence and treatment outcome. Ann Surg Oncol. 2014;21:1706\u201310.","journal-title":"Ann Surg Oncol"},{"key":"3368_CR4","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1002\/hed.23791","volume":"37","author":"S Abu-Ghanem","year":"2015","unstructured":"Abu-Ghanem S, Horowitz G, Abergel A, Yehuda M, Gutfeld O, Carmel NN, Fliss DM. Elective neck irradiation versus observation in squamous cell carcinoma of the maxillary sinus with N0 neck: a meta-analysis and review of the literature. Head Neck. 2015;37:1823\u20138.","journal-title":"Head Neck"},{"key":"3368_CR5","first-page":"219","volume":"24","author":"H Peng","year":"2015","unstructured":"Peng H, Ye MC, Wang LP, Li RX, Zhou Y, Wang Y, Zhu WZ. [Analysis of the outcomes of squamous cell carcinoma of maxillary sinus with 3 different comprehensive treatments]. 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Head Neck. 2023;45:1692\u2013703.","journal-title":"Head Neck"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-024-03368-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12957-024-03368-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-024-03368-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T09:38:46Z","timestamp":1713346726000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjso.biomedcentral.com\/articles\/10.1186\/s12957-024-03368-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,15]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3368"],"URL":"https:\/\/doi.org\/10.1186\/s12957-024-03368-8","relation":{},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,15]]},"assertion":[{"value":"13 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by Our Hospital Institutional Research Committee, and written informed consent for medical research was obtained from all patients prior to initial treatment. All methods were performed in accordance with relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"95"}}