{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T16:24:24Z","timestamp":1780503864422,"version":"3.54.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T00:00:00Z","timestamp":1735948800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T00:00:00Z","timestamp":1735948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"4+X Clinical Research Project of Women\u2019s Hospital, School of Medicine, Zhejiang University","award":["ZDFY2022-4X202"],"award-info":[{"award-number":["ZDFY2022-4X202"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82472891"],"award-info":[{"award-number":["82472891"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Key Program of Zhejiang Province Natural Science Foundation of China","award":["LZ24H160001"],"award-info":[{"award-number":["LZ24H160001"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"DOI":"10.1186\/s12957-024-03636-7","type":"journal-article","created":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T03:09:06Z","timestamp":1735960146000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinicopathological and prognostic factor analyses of primary fallopian tube carcinoma and high-grade serous ovarian cancer: a single-institution retrospective study"],"prefix":"10.1186","volume":"23","author":[{"given":"Mengyan","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianchen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,4]]},"reference":[{"issue":"5","key":"3636_CR1","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1002\/ijc.10970","volume":"104","author":"A Riska","year":"2003","unstructured":"Riska A, Leminen A, Pukkala E. Sociodemographic determinants of incidence of primary fallopian tube carcinoma, Finland 1953-97. Int J Cancer. 2003;104(5):643\u20135.","journal-title":"Int J Cancer"},{"issue":"6","key":"3636_CR2","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1080\/08941939.2022.2048142","volume":"35","author":"Y Xiao","year":"2022","unstructured":"Xiao Y, Liu YX, Li RN, Wei X, Wang QM, Gu QY, Linghu H. Lymphadenectomy in primary fallopian tube Cancer is Associated with Improved Survival. J Invest Surg. 2022;35(6):1417\u201323.","journal-title":"J Invest Surg"},{"issue":"3","key":"3636_CR3","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.tjog.2014.07.003","volume":"53","author":"HC Horng","year":"2014","unstructured":"Horng HC, Teng SW, Huang BS, Sun HD, Yen MS, Wang PH, et al. Primary fallopian tube cancer: domestic data and up-to-date review. Taiwan J Obstet Gynecol. 2014;53(3):287\u201392.","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"11","key":"3636_CR4","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/s41568-022-00503-z","volume":"22","author":"LE Kandalaft","year":"2022","unstructured":"Kandalaft LE, Dangaj Laniti D, Coukos G. Immunobiology of high-grade serous ovarian cancer: lessons for clinical translation. Nat Rev Cancer. 2022;22(11):640\u201356.","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"3636_CR5","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s12943-021-01424-5","volume":"20","author":"AL Drumond-Bock","year":"2021","unstructured":"Drumond-Bock AL, Bieniasz M. The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis. Mol Cancer. 2021;20(1):145.","journal-title":"Mol Cancer"},{"issue":"5","key":"3636_CR6","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/s41571-024-00881-3","volume":"21","author":"PM Webb","year":"2024","unstructured":"Webb PM, Jordan SJ. Global epidemiology of epithelial ovarian cancer. Nat Rev Clin Oncol. 2024;21(5):389\u2013400.","journal-title":"Nat Rev Clin Oncol"},{"key":"3636_CR7","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.ygyno.2024.01.034","volume":"184","author":"S Somasegar","year":"2024","unstructured":"Somasegar S, Reddy RA, Chow S, Dorigo O, Renz M, Karam A. Trends in ovarian, fallopian tube, and primary peritoneal cancer incidence, mortality, and survival: a 15-year population-based analysis. Gynecol Oncol. 2024;184:190\u20137.","journal-title":"Gynecol Oncol"},{"issue":"3","key":"3636_CR8","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1097\/PAS.0b013e3181cf3d79","volume":"34","author":"RJ Kurman","year":"2010","unstructured":"Kurman RJ, Shih Ie M. The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am J Surg Pathol. 2010;34(3):433\u201343.","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"3636_CR9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3121\/cmr.2007.702","volume":"5","author":"CP Crum","year":"2007","unstructured":"Crum CP, Drapkin R, Kindelberger D, Medeiros F, Miron A, Lee Y. Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin Med Res. 2007;5(1):35\u201344.","journal-title":"Clin Med Res"},{"issue":"1","key":"3636_CR10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.ajpath.2020.09.006","volume":"191","author":"IM Shih","year":"2021","unstructured":"Shih IM, Wang Y, Wang TL. The origin of Ovarian Cancer species and Precancerous Landscape. Am J Pathol. 2021;191(1):26\u201339.","journal-title":"Am J Pathol"},{"key":"3636_CR11","doi-asserted-by":"crossref","unstructured":"Wang Y, Duval AJ, Adli M, Matei D. Biology-driven therapy advances in high-grade serous ovarian cancer. J Clin Invest. 2024;134(1).","DOI":"10.1172\/JCI174013"},{"issue":"8","key":"3636_CR12","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1097\/PAS.0b013e318282da7f","volume":"37","author":"JG Bijron","year":"2013","unstructured":"Bijron JG, Seldenrijk CA, Zweemer RP, Lange JG, Verheijen RH, van Diest PJ. Fallopian tube intraluminal tumor spread from noninvasive precursor lesions: a novel metastatic route in early pelvic carcinogenesis. Am J Surg Pathol. 2013;37(8):1123\u201330.","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"3636_CR13","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/S0090-8258(03)00365-2","volume":"90","author":"JM Piek","year":"2003","unstructured":"Piek JM, Verheijen RH, Kenemans P, Massuger LF, Bulten H, van Diest PJ. BRCA1\/2-related ovarian cancers are of tubal origin: a hypothesis. Gynecol Oncol. 2003;90(2):491.","journal-title":"Gynecol Oncol"},{"issue":"1","key":"3636_CR14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/GCO.0000000000000340","volume":"29","author":"PT Kroeger Jr","year":"2017","unstructured":"Kroeger PT Jr., Drapkin R. Pathogenesis and heterogeneity of ovarian cancer. Curr Opin Obstet Gynecol. 2017;29(1):26\u201334.","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"9","key":"3636_CR15","doi-asserted-by":"publisher","first-page":"972","DOI":"10.6004\/jnccn.2022.0047","volume":"20","author":"DK Armstrong","year":"2022","unstructured":"Armstrong DK, Alvarez RD, Backes FJ, Bakkum-Gamez JN, Barroilhet L, Behbakht K, et al. NCCN Guidelines\u00ae insights: ovarian Cancer, Version 3.2022. J Natl Compr Canc Netw. 2022;20(9):972\u201380.","journal-title":"J Natl Compr Canc Netw"},{"issue":"12","key":"3636_CR16","doi-asserted-by":"publisher","first-page":"3298","DOI":"10.1002\/cncr.23957","volume":"113","author":"SL Wethington","year":"2008","unstructured":"Wethington SL, Herzog TJ, Seshan VE, Bansal N, Schiff PB, Burke WM, et al. Improved survival for fallopian tube cancer: a comparison of clinical characteristics and outcome for primary fallopian tube and ovarian cancer. Cancer. 2008;113(12):3298\u2013306.","journal-title":"Cancer"},{"issue":"4","key":"3636_CR17","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/01.ogx.0000158506.23663.79","volume":"60","author":"TV Ajithkumar","year":"2005","unstructured":"Ajithkumar TV, Minimole AL, John MM, Ashokkumar OS. Primary fallopian tube carcinoma. Obstet Gynecol Surv. 2005;60(4):247\u201352.","journal-title":"Obstet Gynecol Surv"},{"issue":"12","key":"3636_CR18","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1080\/00016340701771034","volume":"86","author":"A Riska","year":"2007","unstructured":"Riska A, Leminen A. Updating on primary fallopian tube carcinoma. Acta Obstet Gynecol Scand. 2007;86(12):1419\u201326.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"3636_CR19","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.ejogrb.2013.03.023","volume":"169","author":"E Kalampokas","year":"2013","unstructured":"Kalampokas E, Kalampokas T, Tourountous I. Primary fallopian tube carcinoma. Eur J Obstet Gynecol Reprod Biol. 2013;169(2):155\u201361.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"3636_CR20","doi-asserted-by":"crossref","unstructured":"Lisio MA, Fu L, Goyeneche A, Gao ZH, Telleria C. High-Grade Serous Ovarian Cancer: Basic sciences, clinical and therapeutic standpoints. Int J Mol Sci. 2019;20(4).","DOI":"10.3390\/ijms20040952"},{"issue":"2","key":"3636_CR21","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.anndiagpath.2012.10.001","volume":"17","author":"I Alvarado-Cabrero","year":"2013","unstructured":"Alvarado-Cabrero I, Stolnicu S, Kiyokawa T, Yamada K, Nikaido T, Santiago-Payan H. Carcinoma of the fallopian tube: results of a multi-institutional retrospective analysis of 127 patients with evaluation of staging and prognostic factors. Ann Diagn Pathol. 2013;17(2):159\u201364.","journal-title":"Ann Diagn Pathol"},{"issue":"2","key":"3636_CR22","first-page":"99","volume":"22","author":"E Akkaya","year":"2018","unstructured":"Akkaya E, Sanci M, Kulhan NG, Kulhan M, Nayki U, Nayki C, et al. Prognostic factors of primary fallopian tube carcinoma. Contemp Oncol (Pozn). 2018;22(2):99\u2013104.","journal-title":"Contemp Oncol (Pozn)"},{"issue":"2","key":"3636_CR23","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.3390\/curroncol28020110","volume":"28","author":"M Liontos","year":"2021","unstructured":"Liontos M, Papatheodoridi A, Andrikopoulou A, Thomakos N, Haidopoulos D, Rodolakis A, et al. Management of the Elderly patients with high-Grade Serous Ovarian Cancer in the REAL-WORLD setting. Curr Oncol. 2021;28(2):1143\u201352.","journal-title":"Curr Oncol"},{"issue":"7","key":"3636_CR24","first-page":"494","volume":"110","author":"RK Aich","year":"2012","unstructured":"Aich RK, Dasgupta S, Chakraborty B, Karim R, Bhattacharya J, Sen P. Primary fallopian tube carcinoma with metastasis in the contralateral ovary. J Indian Med Assoc. 2012;110(7):494\u20135.","journal-title":"J Indian Med Assoc"},{"issue":"10 Suppl","key":"3636_CR25","doi-asserted-by":"publisher","first-page":"2615","DOI":"10.1002\/cncr.11339","volume":"97","author":"MT Goodman","year":"2003","unstructured":"Goodman MT, Howe HL. Descriptive epidemiology of ovarian cancer in the United States, 1992\u20131997. Cancer. 2003;97(10 Suppl):2615\u201330.","journal-title":"Cancer"},{"issue":"10","key":"3636_CR26","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.1002\/1097-0142(20001115)89:10<2076::AID-CNCR7>3.0.CO;2-V","volume":"89","author":"M Baekelandt","year":"2000","unstructured":"Baekelandt M, Jorunn Nesbakken A, Kristensen GB, Trope CG, Abeler VM. Carcinoma of the fallopian tube. Cancer. 2000;89(10):2076\u201384.","journal-title":"Cancer"},{"issue":"7","key":"3636_CR27","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1111\/jog.15293","volume":"48","author":"D Mi","year":"2022","unstructured":"Mi D, Zhang Y, Chen S. HE4 is associated with clinical risk prognostic factors and survival outcome in primary fallopian tube carcinoma patients. J Obstet Gynaecol Res. 2022;48(7):1897\u2013903.","journal-title":"J Obstet Gynaecol Res"},{"issue":"3","key":"3636_CR28","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1006\/gyno.1993.1063","volume":"48","author":"LE Puls","year":"1993","unstructured":"Puls LE, Davey DD, DePriest PD, Gallion HH, van Nagell JR Jr., Hunter JE, Pavlik EJ. Immunohistochemical staining for CA-125 in fallopian tube carcinomas. Gynecol Oncol. 1993;48(3):360\u20133.","journal-title":"Gynecol Oncol"},{"issue":"7","key":"3636_CR29","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1097\/IGC.0b013e318220fc46","volume":"21","author":"AA Shamshirsaz","year":"2011","unstructured":"Shamshirsaz AA, Buekers T, Degeest K, Bender D, Zamba G, Goodheart MJ. A single-institution evaluation of factors important in fallopian tube carcinoma recurrence and survival. Int J Gynecol cancer: Official J Int Gynecol Cancer Soc. 2011;21(7):1232\u201340.","journal-title":"Int J Gynecol cancer: Official J Int Gynecol Cancer Soc"},{"issue":"2","key":"3636_CR30","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1006\/gyno.2002.6743","volume":"86","author":"C Kosary","year":"2002","unstructured":"Kosary C, Trimble EL. Treatment and survival for women with fallopian tube carcinoma: a population-based study. Gynecol Oncol. 2002;86(2):190\u20131.","journal-title":"Gynecol Oncol"},{"issue":"1","key":"3636_CR31","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1159\/000010061","volume":"47","author":"AC Rosen","year":"1999","unstructured":"Rosen AC, Klein M, Hafner E, Lahousen M, Graf AH, Reiner A. Management and prognosis of primary fallopian tube carcinoma. Austrian Cooperative Study Group for Fallopian Tube Carcinoma. Gynecol Obstet Invest. 1999;47(1):45\u201351.","journal-title":"Gynecol Obstet Invest"},{"issue":"2","key":"3636_CR32","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1006\/gyno.2001.6134","volume":"81","author":"A Gadducci","year":"2001","unstructured":"Gadducci A, Landoni F, Sartori E, Maggino T, Zola P, Gabriele A, et al. Analysis of treatment failures and survival of patients with fallopian tube carcinoma: a cooperation task force (CTF) study. Gynecol Oncol. 2001;81(2):150\u20139.","journal-title":"Gynecol Oncol"},{"issue":"3","key":"3636_CR33","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1006\/gyno.1998.5267","volume":"72","author":"I Alvarado-Cabrero","year":"1999","unstructured":"Alvarado-Cabrero I, Young RH, Vamvakas EC, Scully RE. Carcinoma of the fallopian tube: a clinicopathological study of 105 cases with observations on staging and prognostic factors. Gynecol Oncol. 1999;72(3):367\u201379.","journal-title":"Gynecol Oncol"},{"issue":"5","key":"3636_CR34","first-page":"611","volume":"25","author":"G Tulunay","year":"2004","unstructured":"Tulunay G, Arvas M, Demir B, Demirkiran F, Boran N, Bese T, et al. Primary fallopian tube carcinoma: a retrospective multicenter study. Eur J Gynaecol Oncol. 2004;25(5):611\u20134.","journal-title":"Eur J Gynaecol Oncol"},{"issue":"3","key":"3636_CR35","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1097\/IGC.0000000000000648","volume":"26","author":"L Bao","year":"2016","unstructured":"Bao L, Ding Y, Cai Q, Ning Y, Hu W, Xue X, et al. Primary fallopian tube carcinoma: a single-Institution experience of 101 cases: a retrospective study. Int J Gynecol cancer: Official J Int Gynecol Cancer Soc. 2016;26(3):424\u201330.","journal-title":"Int J Gynecol cancer: Official J Int Gynecol Cancer Soc"},{"issue":"1","key":"3636_CR36","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/BF02770629","volume":"253","author":"M Klein","year":"1993","unstructured":"Klein M, Rosen A, Lahousen M, Graf A, Vavra N, Beck A. Radical lymphadenectomy in the primary carcinoma of the fallopian tube. Arch Gynecol Obstet. 1993;253(1):21\u20135.","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"3636_CR37","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1002\/1097-0142(19890301)63:5<836::AID-CNCR2820630507>3.0.CO;2-5","volume":"63","author":"WA Peters 3rd","year":"1989","unstructured":"Peters WA 3rd, Andersen WA, Hopkins MP. Results of chemotherapy in advanced carcinoma of the fallopian tube. Cancer. 1989;63(5):836\u20138.","journal-title":"Cancer"},{"issue":"1","key":"3636_CR38","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1097\/00000421-199402000-00015","volume":"17","author":"D Pectasides","year":"1994","unstructured":"Pectasides D, Barbounis V, Sintila A, Varthalitis I, Dimitriadis M, Athanassiou A. Treatment of primary fallopian tube carcinoma with cisplatin-containing chemotherapy. Am J Clin Oncol. 1994;17(1):68\u201371.","journal-title":"Am J Clin Oncol"},{"issue":"1","key":"3636_CR39","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1006\/gyno.2000.6012","volume":"80","author":"ML Gemignani","year":"2001","unstructured":"Gemignani ML, Hensley ML, Cohen R, Venkatraman E, Saigo PE, Barakat RR. Paclitaxel-based chemotherapy in carcinoma of the fallopian tube. Gynecol Oncol. 2001;80(1):16\u201320.","journal-title":"Gynecol Oncol"},{"issue":"2","key":"3636_CR40","first-page":"108","volume":"20","author":"H Ben-Hur","year":"1999","unstructured":"Ben-Hur H, Dgani R, Ben-Arie A, Open M, Shani A, Hagay Z. Diagnostic dilemmas and current therapy of fallopian tube cancer. Eur J Gynaecol Oncol. 1999;20(2):108\u20139.","journal-title":"Eur J Gynaecol Oncol"},{"issue":"3","key":"3636_CR41","first-page":"375","volume":"60","author":"EA Ul\u2019rikh","year":"2014","unstructured":"Ul\u2019rikh EA, Papunidi MD, Urmancheeva AF, Matsko DE. [Fallopian tube carcinoma: clinical and morphological features, analysis of 69 cases]. Vopr Onkol. 2014;60(3):375\u20138.","journal-title":"Vopr Onkol"},{"issue":"1","key":"3636_CR42","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s10147-010-0128-8","volume":"16","author":"YJ Koo","year":"2011","unstructured":"Koo YJ, Im KS, Kwon YS, Lee IH, Kim TJ, Lim KT, et al. Primary fallopian tube carcinoma: a clinicopathological analysis of a rare entity. Int J Clin Oncol. 2011;16(1):45\u20139.","journal-title":"Int J Clin Oncol"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-024-03636-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12957-024-03636-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-024-03636-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T15:02:21Z","timestamp":1736002941000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjso.biomedcentral.com\/articles\/10.1186\/s12957-024-03636-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,4]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3636"],"URL":"https:\/\/doi.org\/10.1186\/s12957-024-03636-7","relation":{},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,4]]},"assertion":[{"value":"20 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocols were approved by the Ethics committee of Women\u2019s Hospital of Zhejiang University (IRB20210122R). Written informed consent was obtained from all patients participating in the study. We confirmed that all methods were carried out in accordance with relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors declare that there is no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"8"}}