{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:22:58Z","timestamp":1772166178497,"version":"3.50.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]},{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]},{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]},{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]},{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]},{"name":"2020 Key Research and Development Program of Anhui Province","award":["202004j07020009"],"award-info":[{"award-number":["202004j07020009"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"DOI":"10.1186\/s12957-025-04074-9","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T16:09:10Z","timestamp":1763136550000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Is conformal thyroidectomy feasible? A 5-10-year follow-up study of residual thyroid in 2512 cases after thyroidectomy"],"prefix":"10.1186","volume":"23","author":[{"given":"Lisen","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yigang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuzhi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weijia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingxin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gongsheng","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"issue":"5","key":"4074_CR1","first-page":"425","volume":"331","author":"L Boucai","year":"2024","unstructured":"Boucai L, Zafereo M, Cabanillas ME. Thyroid Cancer: Rev Jama. 2024;331(5):425\u201335.","journal-title":"Thyroid Cancer: Rev Jama"},{"issue":"1","key":"4074_CR2","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1210\/jc.2014-3039","volume":"100","author":"MA Adam","year":"2015","unstructured":"Adam MA, Pura J, Goffredo P, Dinan MA, Hyslop T, Reed SD, et al. Impact of extent of surgery on survival for papillary thyroid cancer patients younger than 45 years. J Clin Endocrinol Metab. 2015;100(1):115\u201321.","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"4074_CR3","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1097\/SLA.0b013e31814697d9","volume":"246","author":"KY Bilimoria","year":"2007","unstructured":"Bilimoria KY, Bentrem DJ, Ko CY, Stewart AK, Winchester DP, Talamonti MS, et al. Extent of surgery affects survival for papillary thyroid cancer. Ann Surg. 2007;246(3):375\u201381. discussion 81\u2009\u2013\u20094.","journal-title":"Ann Surg"},{"issue":"4","key":"4074_CR4","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1097\/SLA.0000000000000925","volume":"260","author":"MA Adam","year":"2014","unstructured":"Adam MA, Pura J, Gu L, Dinan MA, Tyler DS, Reed SD, et al. Extent of surgery for papillary thyroid cancer is not associated with survival. Ann Surg. 2014;260(4):601\u20137.","journal-title":"Ann Surg"},{"issue":"8","key":"4074_CR5","doi-asserted-by":"publisher","first-page":"925","DOI":"10.6004\/jnccn.2022.0040","volume":"20","author":"RI Haddad","year":"2022","unstructured":"Haddad RI, Bischoff L, Ball D, Bernet V, Blomain E, Busaidy NL, et al. Thyroid carcinoma, version 2.2022, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2022;20(8):925\u201351.","journal-title":"J Natl Compr Canc Netw"},{"issue":"2","key":"4074_CR6","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.suronc.2015.04.005","volume":"24","author":"FI Macedo","year":"2015","unstructured":"Macedo FI, Mittal VK. Total thyroidectomy versus lobectomy as initial operation for small unilateral papillary thyroid carcinoma: a meta-analysis. Surg Oncol. 2015;24(2):117\u201322.","journal-title":"Surg Oncol"},{"issue":"1","key":"4074_CR7","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/s00268-013-2224-1","volume":"38","author":"K Matsuzu","year":"2014","unstructured":"Matsuzu K, Sugino K, Masudo K, Nagahama M, Kitagawa W, Shibuya H, et al. Thyroid lobectomy for papillary thyroid cancer: long-term follow-up study of 1,088 cases. World J Surg. 2014;38(1):68\u201379.","journal-title":"World J Surg"},{"issue":"2","key":"4074_CR8","doi-asserted-by":"publisher","first-page":"678","DOI":"10.21037\/gs-20-712","volume":"10","author":"JJ Diez","year":"2021","unstructured":"Diez JJ, Alcazar V, Iglesias P, Romero-Lluch A, Sastre J, Corral BP, et al. Thyroid lobectomy in patients with differentiated thyroid cancer: an analysis of the clinical outcomes in a nationwide multicenter study. Gland Surg. 2021;10(2):678\u201389.","journal-title":"Gland Surg"},{"issue":"9","key":"4074_CR9","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1177\/00031348211038557","volume":"87","author":"MM Merten","year":"2021","unstructured":"Merten MM, Foster T, Lyden M, Henry M, Regina Castro M. Favorable early outcomes with thyroid lobectomy for low-risk papillary thyroid cancer: the Mayo clinic experience. Am Surg. 2021;87(9):1374\u20138.","journal-title":"Am Surg"},{"issue":"1","key":"4074_CR10","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-11307-1","volume":"23","author":"S Xu","year":"2023","unstructured":"Xu S, Huang H, Dong H, Wang X, Xu Z, Liu S, et al. Association between surgical extent and recurrence in unilateral intermediate- to high-risk papillary thyroid cancer. BMC Cancer. 2023;23(1):880.","journal-title":"BMC Cancer"},{"key":"4074_CR11","doi-asserted-by":"publisher","unstructured":"Li C, Cao J, Chen G-S, Yang X-D, Jiang K-W, Ye Y-J. Conformal thyroidectomy is a feasible option in papillary thyroid microcarcinoma: a retrospective cohort study with 10-year follow-up results. Langenbeck\u2019s Archives Surg. 2024;409(1). https:\/\/doi.org\/10.1007\/s00423-024-03333-9.","DOI":"10.1007\/s00423-024-03333-9"},{"issue":"3","key":"4074_CR12","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.amjoto.2019.03.016","volume":"40","author":"HJ Nahm","year":"2019","unstructured":"Nahm HJ, Choi SJ, Lim YC. Conservative thyroidectomy for papillary thyroid microcarcinoma. Am J Otolaryngol. 2019;40(3):427\u201330.","journal-title":"Am J Otolaryngol"},{"issue":"6","key":"4074_CR13","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1159\/000510620","volume":"10","author":"M Bosset","year":"2021","unstructured":"Bosset M, Bonjour M, Castellnou S, Hafdi-Nejjari Z, Bournaud-Salinas C, Decaussin-Petrucci M, et al. Long-term outcome of lobectomy for thyroid cancer. Eur Thyroid J. 2021;10(6):486\u201394.","journal-title":"Eur Thyroid J"},{"issue":"1","key":"4074_CR14","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1111\/cen.13336","volume":"87","author":"MJ Kim","year":"2017","unstructured":"Kim MJ, Lee MC, Lee GH, Choi HS, Cho SW, Kim SJ, et al. Extent of surgery did not affect recurrence during 7-years follow-up in papillary thyroid cancer sized 1\u20134\u00a0cm: preliminary results. Clin Endocrinol (Oxf). 2017;87(1):80\u20136.","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"1","key":"4074_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/thy.2015.0020","volume":"26","author":"BR Haugen","year":"2016","unstructured":"Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26(1):1\u2013133.","journal-title":"Thyroid"},{"key":"4074_CR16","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.723631","volume":"12","author":"T Ma","year":"2021","unstructured":"Ma T, Wang H, Liu J, Zou J, Liu S. Should contralateral nodules be an indication of total or completion thyroidectomy for patients with unilateral papillary thyroid carcinoma? Front Endocrinol (Lausanne). 2021;12:723631.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"4074_CR17","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/s41568-019-0222-9","volume":"20","author":"M Fane","year":"2020","unstructured":"Fane M, Weeraratna AT. How the ageing microenvironment influences tumour progression. Nat Rev Cancer. 2020;20(2):89\u2013106.","journal-title":"Nat Rev Cancer"},{"issue":"7","key":"4074_CR18","doi-asserted-by":"publisher","first-page":"2672","DOI":"10.1210\/jc.2006-0417","volume":"91","author":"AG Saad","year":"2006","unstructured":"Saad AG, Kumar S, Ron E, Lubin JH, Stanek J, Bove KE, et al. Proliferative activity of human thyroid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposure. J Clin Endocrinol Metab. 2006;91(7):2672\u20137.","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"4074_CR19","first-page":"232","volume":"45","author":"A Faggiano","year":"2004","unstructured":"Faggiano A, Coulot J, Bellon N, Talbot M, Caillou B, Ricard M, et al. Age-dependent variation of follicular size and expression of iodine transporters in human thyroid tissue. J Nucl Med. 2004;45(2):232\u20137.","journal-title":"J Nucl Med"},{"issue":"4","key":"4074_CR20","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1677\/erc.1.00880","volume":"12","author":"B Jarzab","year":"2005","unstructured":"Jarzab B, Handkiewicz-Junak D, Wloch J. Juvenile differentiated thyroid carcinoma and the role of radioiodine in its treatment: a qualitative review. Endocr Relat Cancer. 2005;12(4):773\u2013803.","journal-title":"Endocr Relat Cancer"},{"issue":"2","key":"4074_CR21","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1001\/jamaoncol.2016.3288","volume":"3","author":"R Liu","year":"2017","unstructured":"Liu R, Bishop J, Zhu G, Zhang T, Ladenson PW, Xing M. Mortality risk stratification by combining BRAF V600E and TERT promoter mutations in papillary thyroid cancer: genetic duet of BRAF and TERT promoter mutations in thyroid cancer mortality. JAMA Oncol. 2017;3(2):202\u20138.","journal-title":"JAMA Oncol"},{"issue":"5","key":"4074_CR22","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1200\/JCO.2017.74.5497","volume":"36","author":"X Shen","year":"2018","unstructured":"Shen X, Zhu G, Liu R, Viola D, Elisei R, Puxeddu E, et al. Patient age-associated mortality risk is differentiated by BRAF V600E status in papillary thyroid cancer. J Clin Oncol. 2018;36(5):438\u201345.","journal-title":"J Clin Oncol"},{"issue":"5","key":"4074_CR23","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1200\/JCO.2017.76.2583","volume":"36","author":"MR Haymart","year":"2018","unstructured":"Haymart MR, Is. BRAF V600E mutation the explanation for Age-Associated mortality risk in patients with papillary thyroid cancer? J Clin Oncol. 2018;36(5):433\u20134.","journal-title":"J Clin Oncol"},{"issue":"1","key":"4074_CR24","first-page":"55","volume":"68","author":"ND Perrier","year":"2018","unstructured":"Perrier ND, Brierley JD, Tuttle RM. Differentiated and anaplastic thyroid carcinoma: major changes in the American joint committee on cancer eighth edition cancer staging manual. CA Cancer J Clin. 2018;68(1):55\u201363.","journal-title":"CA Cancer J Clin"},{"key":"4074_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.777345","volume":"13","author":"AK Siraj","year":"2022","unstructured":"Siraj AK, Parvathareddy SK, Annaiyappanaidu P, Siraj N, Al-Sobhi SS, Al-Dayel F, et al. Male sex is an independent predictor of recurrence-free survival in middle Eastern papillary thyroid carcinoma. Front Endocrinol (Lausanne). 2022;13:777345.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"4074_CR26","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/hed.25356","volume":"41","author":"JB Choi","year":"2019","unstructured":"Choi JB, Lee SG, Kim MJ, Kim TH, Ban EJ, Lee CR, et al. Oncologic outcomes in patients with 1-cm to 4-cm differentiated thyroid carcinoma according to extent of thyroidectomy. Head Neck. 2019;41(1):56\u201363.","journal-title":"Head Neck"},{"key":"4074_CR27","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ijsu.2017.12.035","volume":"50","author":"KR Joseph","year":"2018","unstructured":"Joseph KR, Edirimanne S, Eslick GD. Multifocality as a prognostic factor in thyroid cancer: a meta-analysis. Int J Surg. 2018;50:121\u20135.","journal-title":"Int J Surg"},{"issue":"2","key":"4074_CR28","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00423-013-1145-7","volume":"399","author":"M Iacobone","year":"2014","unstructured":"Iacobone M, Jansson S, Barczynski M, Goretzki P. Multifocal papillary thyroid carcinoma\u2013a consensus report of the European society of endocrine surgeons (ESES). Langenbecks Arch Surg. 2014;399(2):141\u201354.","journal-title":"Langenbecks Arch Surg"},{"issue":"1","key":"4074_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-022-02869-8","volume":"20","author":"Y Omi","year":"2022","unstructured":"Omi Y, Haniu K, Kamio H, Fujimoto M, Yoshida Y, Horiuchi K, et al. Pathological multifocality is not a prognosis factor of papillary thyroid carcinoma: a single-center, retrospective study. World J Surg Oncol. 2022;20(1):394.","journal-title":"World J Surg Oncol"},{"issue":"27","key":"4074_CR30","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007461","volume":"96","author":"H Huang","year":"2017","unstructured":"Huang H, Liu S, Xu Z, Ni S, Zhang Z, Wang X. Long-term outcome of thyroid lobectomy for unilateral multifocal papillary carcinoma. Medicine. 2017;96(27):e7461.","journal-title":"Medicine"},{"issue":"6","key":"4074_CR31","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1308\/rcsann.2021.0224","volume":"104","author":"J Lau","year":"2022","unstructured":"Lau J, Lee J, Mahipal M, Yang SP, Tan WB, Yuan NK, et al. Hashimoto\u2019s thyroiditis on outcomes in papillary thyroid cancer revisited: experience from South East Asia. Ann R Coll Surg Engl. 2022;104(6):465\u201371.","journal-title":"Ann R Coll Surg Engl"},{"issue":"3","key":"4074_CR32","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1007\/s12022-011-9164-9","volume":"22","author":"BY Huang","year":"2011","unstructured":"Huang BY, Hseuh C, Chao TC, Lin KJ, Lin JD. Well-differentiated thyroid carcinoma with concomitant Hashimoto\u2019s thyroiditis present with less aggressive clinical stage and low recurrence. Endocr Pathol. 2011;22(3):144\u20139.","journal-title":"Endocr Pathol"},{"issue":"4","key":"4074_CR33","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.amjoto.2012.12.013","volume":"34","author":"D Ahn","year":"2013","unstructured":"Ahn D, Sohn JH, Kim JH, Shin CM, Jeon JH, Park JY. Preoperative subclinical hypothyroidism in patients with papillary thyroid carcinoma. Am J Otolaryngol. 2013;34(4):312\u20139.","journal-title":"Am J Otolaryngol"},{"issue":"1","key":"4074_CR34","doi-asserted-by":"publisher","first-page":"99","DOI":"10.21147\/j.issn.1000-9604.2019.01.06","volume":"31","author":"Chinese Society of Clinical Oncology","year":"2019","unstructured":"Chinese Society of Clinical Oncology. (CSCO) diagnosis and treatment guidelines for persistent\/recurrent and metastatic differentiated thyroid cancer 2018 (English version). Chin J Cancer Res. 2019;31(1):99\u2013116.","journal-title":"Chin J Cancer Res"},{"issue":"2","key":"4074_CR35","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s12020-023-03548-8","volume":"83","author":"BJ Gigliotti","year":"2024","unstructured":"Gigliotti BJ, Jasim S. Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy. Endocrine. 2024;83(2):251\u20138.","journal-title":"Endocrine"},{"key":"4074_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2024.02.037","volume":"236","author":"H Nakanishi","year":"2024","unstructured":"Nakanishi H, Wang R, Miangul S, Kim GE, Segun-Omosehin OA, Bourdakos NE, et al. Clinical outcomes of outpatient thyroidectomy: a systematic review and single-arm meta-analysis. Am J Surg. 2024;236:115694.","journal-title":"Am J Surg"},{"issue":"1","key":"4074_CR37","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/hed.24934","volume":"40","author":"DJ Lee","year":"2018","unstructured":"Lee DJ, Chin CJ, Hong CJ, Perera S, Witterick IJ. Outpatient versus inpatient thyroidectomy: a systematic review and meta-analysis. Head Neck. 2018;40(1):192\u2013202.","journal-title":"Head Neck"},{"issue":"1","key":"4074_CR38","doi-asserted-by":"publisher","first-page":"32730","DOI":"10.1038\/s41598-025-18227-z","volume":"15","author":"O Aslan","year":"2025","unstructured":"Aslan O, Sahin M, Topcu R, Percem AK, Sezikli I, Yuksek MA, et al. Surgical outcomes and complications of completion thyroidectomy: a retrospective study. Sci Rep. 2025;15(1):32730.","journal-title":"Sci Rep"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-025-04074-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12957-025-04074-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-025-04074-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T01:04:32Z","timestamp":1763168672000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjso.biomedcentral.com\/articles\/10.1186\/s12957-025-04074-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,14]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4074"],"URL":"https:\/\/doi.org\/10.1186\/s12957-025-04074-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7033458\/v1","asserted-by":"object"}]},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,14]]},"assertion":[{"value":"3 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study involving medical ethics aspects has been reviewed and approved by the Institutional Ethics Committee of the First Affiliated Hospital of Bengbu Medical University. Because the study was retrospective in nature, written informed consent was not required according to the regional guidelines.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"435"}}