{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T02:57:20Z","timestamp":1776394640886,"version":"3.51.2"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"The Primary Health Development Research Center of Sichuan Province Program","award":["SWFZ24-Y-24"],"award-info":[{"award-number":["SWFZ24-Y-24"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"DOI":"10.1186\/s12957-026-04294-7","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T04:49:06Z","timestamp":1773204546000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Habitat model based on transvaginal ultrasound images for non-invasive prediction of lymphatic vessel interstitial infiltration in endometrial cancer"],"prefix":"10.1186","volume":"24","author":[{"given":"Chen","family":"Jiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Yuanyuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huang","family":"Jianghua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Maochun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"4294_CR1","doi-asserted-by":"publisher","first-page":"e080978","DOI":"10.1136\/bmj-2024-080978","volume":"388","author":"BR Corr","year":"2025","unstructured":"Corr BR, Erickson BK, Barber EL, Fisher CM, Slomovitz B. Advances in the management of endometrial cancer. BMJ. 2025;388:e080978.","journal-title":"BMJ"},{"key":"4294_CR2","doi-asserted-by":"publisher","first-page":"4251","DOI":"10.1002\/cncr.34479","volume":"128","author":"KA Cronin","year":"2022","unstructured":"Cronin KA, Scott S, Firth AU, Sung H, Henley SJ, Sherman RL, Siegel RL, Anderson RN, Kohler BA, Benard VB et al. Annual report to the nation on the status of cancer, part 1: National cancer statistics. Cancer. 2022;128:4251\u20134284.","journal-title":"Cancer"},{"key":"4294_CR3","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1097\/PGP.0000000000000596","volume":"39","author":"MM Meydanli","year":"2020","unstructured":"Meydanli MM, Aslan K, \u00d6z M, Muftuoglu KH, Yalcin I, Engin-Ustun Y. Is It Possible to Develop a Prediction Model for Lymphovascular Space Invasion in Endometrioid Endometrial Cancer? Int J Gynecol Pathol. 2020;39:213\u201320.","journal-title":"Int J Gynecol Pathol"},{"key":"4294_CR4","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.ygyno.2016.01.002","volume":"140","author":"S Jorge","year":"2016","unstructured":"Jorge S, Hou JY, Tergas AI, Burke WM, Huang Y, Hu JC, Ananth CV, Neugut AI, Hershman DL, Wright JD. Magnitude of risk for nodal metastasis associated with lymphvascular space invasion for endometrial cancer. Gynecol Oncol. 2016;140:387\u201393.","journal-title":"Gynecol Oncol"},{"key":"4294_CR5","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1245\/s10434-010-1206-x","volume":"18","author":"SJ Chang","year":"2011","unstructured":"Chang SJ, Kong TW, Kim WY, Yoo SC, Yoon JH, Chang KH, Ryu HS. Lymph-vascular space invasion as a significant risk factor for isolated para-aortic lymph node metastasis in endometrial cancer: a study of 203 consecutive patients. Ann Surg Oncol. 2011;18:58\u201364.","journal-title":"Ann Surg Oncol"},{"key":"4294_CR6","doi-asserted-by":"publisher","first-page":"e84","DOI":"10.3802\/jgo.2019.30.e84","volume":"30","author":"G \u00d8rtoft","year":"2019","unstructured":"\u00d8rtoft G, Lausten-Thomsen L, H\u00f8gdall C, Hansen ES, Dueholm M. Lymph-vascular space invasion (LVSI) as a strong and independent predictor for non-locoregional recurrences in endometrial cancer: a Danish Gynecological Cancer Group Study. J Gynecol Oncol. 2019;30:e84.","journal-title":"J Gynecol Oncol"},{"key":"4294_CR7","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s12957-019-1620-x","volume":"17","author":"AE Veade","year":"2019","unstructured":"Veade AE, Foote J, Ehrisman J, Broadwater G, Davidson BA, Lee PS, Secord AA, Berchuck A, Havrilesky LJ. Associations between lymphovascular space invasion, nodal recurrence, and survival in patients with surgical stage I endometrioid endometrial adenocarcinoma. World J Surg Oncol. 2019;17:80.","journal-title":"World J Surg Oncol"},{"key":"4294_CR8","doi-asserted-by":"publisher","first-page":"e473114","DOI":"10.1200\/EDBK-25-473114","volume":"45","author":"KN Moore","year":"2025","unstructured":"Moore KN, Liu JF, Lorusso D. State of the Art: Therapies Now and Around the Corner for Gynecologic Cancers. Am Soc Clin Oncol Educ Book. 2025;45:e473114.","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"4294_CR9","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1007\/s10147-019-01437-7","volume":"24","author":"F De Felice","year":"2019","unstructured":"De Felice F, Marchetti C, Tombolini V, Panici PB. Immune check-point in endometrial cancer. Int J Clin Oncol. 2019;24:910\u20136.","journal-title":"Int J Clin Oncol"},{"key":"4294_CR10","doi-asserted-by":"publisher","first-page":"2730","DOI":"10.1002\/jmri.29344","volume":"60","author":"Y Wang","year":"2024","unstructured":"Wang Y, Liu W, Lu Y, Ling R, Wang W, Li S, Zhang F, Ning Y, Chen X, Yang G, Zhang H. Fully Automated Identification of Lymph Node Metastases and Lymphovascular Invasion in Endometrial Cancer From Multi-Parametric MRI by Deep Learning. J Magn Reson Imaging. 2024;60:2730\u201342.","journal-title":"J Magn Reson Imaging"},{"key":"4294_CR11","doi-asserted-by":"publisher","first-page":"77","DOI":"10.11152\/mu-2961","volume":"24","author":"T Costas","year":"2022","unstructured":"Costas T, Belda R, Alcazar JL. Transvaginal three-dimensional ultrasound for preoperative assessment of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis. Med Ultrason. 2022;24:77\u201384.","journal-title":"Med Ultrason"},{"key":"4294_CR12","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.crad.2022.08.149","volume":"78","author":"C McCague","year":"2023","unstructured":"McCague C, Ramlee S, Reinius M, Selby I, Hulse D, Piyatissa P, Bura V, Crispin-Ortuzar M, Sala E, Woitek R. Introduction to radiomics for a clinical audience. Clin Radiol. 2023;78:83\u201398.","journal-title":"Clin Radiol"},{"key":"4294_CR13","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/s41571-022-00707-0","volume":"20","author":"EP Huang","year":"2023","unstructured":"Huang EP, O\u2019Connor JPB, McShane LM, Giger ML, Lambin P, Kinahan PE, Siegel EL, Shankar LK. Criteria for the translation of radiomics into clinically useful tests. Nat Rev Clin Oncol. 2023;20:69\u201382.","journal-title":"Nat Rev Clin Oncol"},{"key":"4294_CR14","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.annonc.2023.10.125","volume":"35","author":"A Prelaj","year":"2024","unstructured":"Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, et al. Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review. Ann Oncol. 2024;35:29\u201365.","journal-title":"Ann Oncol"},{"key":"4294_CR15","doi-asserted-by":"crossref","unstructured":"Li ZY, Wu SN, Lin P, Jiang MC, Chen C, Lin WJ, Xue ES, Liang RX, Lin ZH. Habitat-based radiomics for revealing tumor heterogeneity and predicting residual cancer burden classification in breast cancer. Clin Breast Cancer 2025 25:444\u201354.","DOI":"10.1016\/j.clbc.2025.01.014"},{"key":"4294_CR16","doi-asserted-by":"publisher","first-page":"e222830","DOI":"10.1148\/radiol.222830","volume":"308","author":"Z Shi","year":"2023","unstructured":"Shi Z, Huang X, Cheng Z, Xu Z, Lin H, Liu C, Chen X, Liu C, Liang C, Lu C, et al. MRI-based Quantification of Intratumoral Heterogeneity for Predicting Treatment Response to Neoadjuvant Chemotherapy in Breast Cancer. Radiology. 2023;308:e222830.","journal-title":"Radiology"},{"key":"4294_CR17","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1158\/1078-0432.CCR-20-2156","volume":"27","author":"JE Park","year":"2021","unstructured":"Park JE, Kim HS, Kim N, Park SY, Kim YH, Kim JH. Spatiotemporal Heterogeneity in Multiparametric Physiologic MRI Is Associated with Patient Outcomes in IDH-Wildtype Glioblastoma. Clin Cancer Res. 2021;27:237\u201345.","journal-title":"Clin Cancer Res"},{"key":"4294_CR18","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/j.acra.2024.10.015","volume":"32","author":"F Li","year":"2025","unstructured":"Li F, Du Y, Liu L, Ma J, Qin Z, Tao S, Yao M, Wu R, Zhao J. Multiparameter and Ultrasound Radiomics Nomogram to Predict the Aggressiveness of Papillary Thyroid Carcinomas: A Multicenter, Retrospective Study. Acad Radiol. 2025;32:1373\u201384.","journal-title":"Acad Radiol"},{"key":"4294_CR19","doi-asserted-by":"publisher","first-page":"e2413702","DOI":"10.1002\/advs.202413702","volume":"12","author":"YH Huang","year":"2025","unstructured":"Huang YH, Shi ZY, Zhu T, Zhou TH, Li Y, Li W, Qiu H, Wang SQ, He LF, Wu ZY, et al. Longitudinal MRI-Driven Multi-Modality Approach for Predicting Pathological Complete Response and B Cell Infiltration in Breast Cancer. Adv Sci (Weinh). 2025;12:e2413702.","journal-title":"Adv Sci (Weinh)"},{"key":"4294_CR20","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1002\/ijgo.14923","volume":"162","author":"JS Berek","year":"2023","unstructured":"Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N. FIGO staging of endometrial cancer: 2023. Int J Gynaecol Obstet. 2023;162:383\u201394.","journal-title":"Int J Gynaecol Obstet"},{"key":"4294_CR21","unstructured":"World Health Organization. Classification of Tumors. Female Genital Tumours. 5th ed. Lyon: International Agency for Research on Cancer; 2022."},{"key":"4294_CR22","unstructured":"Lundberg SM, Lee S-I. A unified approach to interpreting model predictions. Adv Neural Inf Process Syst. 2017;30 :6785\u201395."},{"key":"4294_CR23","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1097\/IGC.0000000000001229","volume":"28","author":"E Cusano","year":"2018","unstructured":"Cusano E, Myers V, Samant R, Sudai T, Keller A, Le T, Grimes EC, Xu S. Prognostic Significance of Lymphovascular Space Invasion in the Absence of Lymph Node Metastases in Early-Stage Endometrial Cancer. Int J Gynecol Cancer. 2018;28:890\u20134.","journal-title":"Int J Gynecol Cancer"},{"key":"4294_CR24","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1111\/apm.12774","volume":"125","author":"NCM Visser","year":"2017","unstructured":"Visser NCM, Werner HMJ, Krakstad C, Mauland KK, Trovik J, Massuger L, Nagtegaal ID, Pijnenborg JMA, Salvesen HB, Bulten J, Stefansson IM. Type of vascular invasion in association with progress of endometrial cancer. Apmis. 2017;125:1084\u201391.","journal-title":"Apmis"},{"key":"4294_CR25","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1016\/j.ultrasmedbio.2022.03.007","volume":"48","author":"L Zhu","year":"2022","unstructured":"Zhu L, Huang R, Li M, Fan Q, Zhao X, Wu X, Dong F. Machine Learning-Based Ultrasound Radiomics for Evaluating the Function of Transplanted Kidneys. Ultrasound Med Biol. 2022;48:1441\u201352.","journal-title":"Ultrasound Med Biol"},{"key":"4294_CR26","doi-asserted-by":"publisher","first-page":"4140","DOI":"10.1007\/s00261-024-04432-3","volume":"49","author":"S Li","year":"2024","unstructured":"Li S, Wang Y, Sun Y, Li D, Zhang Q, Ning Y, Lu Y, Wang W, Zhang H, Yang G. Both intra- and peri-tumoral radiomics signatures can be used to predict lymphatic vascular space invasion and lymphatic metastasis positive status from endometrial cancer MR imaging. Abdom Radiol (NY). 2024;49:4140\u201350.","journal-title":"Abdom Radiol (NY)"},{"key":"4294_CR27","doi-asserted-by":"crossref","unstructured":"Yu Y, Ouyang W, Huang Y, Huang H, Wang Z, Jia X, Huang Z, Lin R, Zhu Y, Yalikun Y et al. AI-Based multimodal Multi-tasks analysis reveals tumor molecular heterogeneity, predicts preoperative lymph node metastasis and prognosis in papillary thyroid carcinoma: a retrospective study. Int J Surg. 2024;111:839\u201356.","DOI":"10.1097\/JS9.0000000000001875"},{"key":"4294_CR28","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.clbc.2025.01.014","volume":"25","author":"ZY Li","year":"2025","unstructured":"Li ZY, Wu SN, Lin P, Jiang MC, Chen C, Lin WJ, Xue ES, Liang RX, Lin ZH. Habitat-Based Radiomics for Revealing Tumor Heterogeneity and Predicting Residual Cancer Burden Classification in Breast Cancer. Clin Breast Cancer. 2025;25:444\u201354.","journal-title":"Clin Breast Cancer"},{"key":"4294_CR29","doi-asserted-by":"publisher","first-page":"1252074","DOI":"10.3389\/fonc.2023.1252074","volume":"13","author":"S Wang","year":"2023","unstructured":"Wang S, Liu X, Wu Y, Jiang C, Luo Y, Tang X, Wang R, Zhang X, Gong J. Habitat-based radiomics enhances the ability to predict lymphovascular space invasion in cervical cancer: a multi-center study. Front Oncol. 2023;13:1252074.","journal-title":"Front Oncol"},{"key":"4294_CR30","doi-asserted-by":"crossref","unstructured":"Wang JJ, Zhang XH, Guo XH, Ying Y, Wang X, Luan ZH, Lv WQ, Wang PF. Prediction of lymphovascular space invision in endometrial cancer based on multi-parameter mri radiomics model. Curr Med Imaging. 2024; 20:e15734056266366.","DOI":"10.2174\/0115734056266366231219111246"},{"key":"4294_CR31","doi-asserted-by":"crossref","unstructured":"Wang Y, Dai A, Wen Y, Sun M, Gao J, Yin Z, Han R. Prediction of high-risk capsule characteristics for recurrence of pleomorphic adenoma in the parotid gland based on habitat imaging and peritumoral radiomics: a two-center study. Acad Radiol. 2025;32:4134\u201345.","DOI":"10.1016\/j.acra.2025.01.030"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12957-026-04294-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-026-04294-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12957-026-04294-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T02:30:17Z","timestamp":1776393017000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12957-026-04294-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,11]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4294"],"URL":"https:\/\/doi.org\/10.1186\/s12957-026-04294-7","relation":{},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,11]]},"assertion":[{"value":"28 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. All methods were carried out in accordance with the institutional guidelines and regulations. This study was approved by Human Research Ethics Committee, Affiliated Hospital of North Sichuan Medical College, approval number REC. 2025ER14-1.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"179"}}