{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T01:29:06Z","timestamp":1769909346395,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod Biol Endocrinol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12958-016-0142-4","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T02:57:22Z","timestamp":1455073042000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Measurement of betamethasone concentration in maternal serum treated for fetal lung maturity; Is it feasible?"],"prefix":"10.1186","volume":"14","author":[{"given":"Raed","family":"Salim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abeer","family":"Suleiman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raul","family":"Colodner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohar","family":"Nachum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee H.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliezer","family":"Shalev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,2,10]]},"reference":[{"key":"142_CR1","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1056\/NEJMoa035140","volume":"348","author":"PJ Meis","year":"2003","unstructured":"National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, Meis PJ, Klebanoff M, Thom E, Dombrowski MP, Sibai B, et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate. N Engl J Med. 2003;348:2379\u201385.","journal-title":"N Engl J Med"},{"key":"142_CR2","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/S0140-6736(02)11476-0","volume":"360","author":"MM Slattery","year":"2002","unstructured":"Slattery MM, Morrison JJ. Preterm delivery. Lancet. 2002;360:1489\u201397.","journal-title":"Lancet"},{"key":"142_CR3","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0378-3782(98)00052-8","volume":"53","author":"M Hack","year":"1999","unstructured":"Hack M, Dandruff AA. Outcomes of children of extremely low birthweight and gestational age in the 1990\u2019s. Early Hum Dev. 1999;53:193\u2013218.","journal-title":"Early Hum Dev"},{"key":"142_CR4","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1677\/joe.0.0450515","volume":"45","author":"GC Liggins","year":"1969","unstructured":"Liggins GC. Premature delivery of fetal lambs infused with glucocorticoids. J Endocrinol. 1969;45:515\u201323.","journal-title":"J Endocrinol"},{"key":"142_CR5","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/AOG.0b013e31820711f0","volume":"117","author":"TD Myles","year":"2011","unstructured":"Myles TD. Steroids - plenty of benefits, but not without risk. Obstet Gynecol. 2011;117:429\u201330.","journal-title":"Obstet Gynecol"},{"key":"142_CR6","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/0002-9378(95)90222-8","volume":"173","author":"PA Crowley","year":"1995","unstructured":"Crowley PA. Antenatal corticosteroid therapy: a meta-analysis of the randomized trials, 1972 to 1994. Am J Obstet Gynecol. 1995;173:322\u201335.","journal-title":"Am J Obstet Gynecol"},{"key":"142_CR7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1001\/jama.1995.03520290065031","volume":"273","author":"Effect of corticosteroids for fetal maturation on perinatal outcomes","year":"1995","unstructured":"Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus development panel on the effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA. 1995;273:413\u20138.","journal-title":"JAMA"},{"key":"142_CR8","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1542\/peds.50.4.515","volume":"50","author":"GC Liggins","year":"1972","unstructured":"Liggins GC, Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics. 1972;50:515\u201325.","journal-title":"Pediatrics"},{"key":"142_CR9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.0004-8666.2003.00052.x","volume":"43","author":"KJ McLaughlin","year":"2003","unstructured":"McLaughlin KJ, Crowther CA, Walker N, Harding JE. Effects of a single course of corticosteroids given more than 7 days before birth: a systematic review. Aust N Z J Obstet Gynaecol. 2003;43:101\u20136.","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"142_CR10","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1055\/s-2007-994355","volume":"13","author":"MA Turrentine","year":"1996","unstructured":"Turrentine MA, Dupras-Wilson P, Wilkins IA. A retrospective analysis of the effect of antenatal steroid administration on the incidence of respiratory distress syndrome in preterm twin pregnancies. Am J Perinatol. 1996;13:351\u20134.","journal-title":"Am J Perinatol"},{"key":"142_CR11","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1080\/j.1600-0412.1999.780508.x","volume":"78","author":"EC Quist-Therson","year":"1999","unstructured":"Quist-Therson EC, Myhr TL, Ohlsson A. Antenatal steroids to prevent respiratory distress syndrome: multiple gestation as an effect modifier. Acta Obstet Gynecol Scand. 1999;78:388\u201392.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"142_CR12","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/AOG.0b013e31820eee00","volume":"117","author":"ACOG Committee on Obstetric Practice","year":"2011","unstructured":"ACOG Committee on Obstetric Practice. ACOG Committee Opinion No. 475: Antenatal corticosteroid therapy for fetal maturation. Obstet Gynecol. 2011;117:422\u20134.","journal-title":"Obstet Gynecol"},{"key":"142_CR13","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/01.AOG.0000232815.80648.01","volume":"108","author":"M Schwab","year":"2006","unstructured":"Schwab M, Coksaygan T, Samtani MN, Jusko WJ, Nathanielsz PW. Kinetics of Betamethasone and Fetal Cardiovascular Adverse Effects in Pregnant Sheep After Different Doses. Obstet Gynecol. 2006;108:617\u201325.","journal-title":"Obstet Gynecol"},{"key":"142_CR14","doi-asserted-by":"crossref","first-page":"186.e1","DOI":"10.1016\/j.ajog.2009.09.033","volume":"202","author":"M Loehle","year":"2010","unstructured":"Loehle M, Schwab M, Kadner S, Maner KM, Gilbert JS, Brenna JT, et al. Dose-response effects of betamethasone on maturation of the fetal sheep lung. Am J Obstet Gynecol. 2010;202:186.e1\u20137.","journal-title":"Am J Obstet Gynecol"},{"key":"142_CR15","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1067\/mob.2002.121654","volume":"186","author":"SV Koenen","year":"2002","unstructured":"Koenen SV, Mecenas CA, Smith GS, Jenkins S, Nathanielsz PW. Effects of maternal betamethasone administration on fetal and maternal blood pressure and heart rate in the baboon at 0.7 of gestation. Am J Obstet Gynecol. 2002;186:812\u20137.","journal-title":"Am J Obstet Gynecol"},{"key":"142_CR16","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0002-9378(99)70160-2","volume":"180","author":"NP French","year":"1999","unstructured":"French NP, Hagan R, Evans SF, Godfrey M, Newnham JP. Repeated antenatal corticosteroids: Size at birth and subsequent development. Am J Obstet Gynecol. 1999;180:114\u201321.","journal-title":"Am J Obstet Gynecol"},{"key":"142_CR17","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0002-9378(16)32697-7","volume":"141","author":"JW Johnson","year":"1981","unstructured":"Johnson JW, Mitzner W, Beck JC, London WT, Sly DL, Lee PA, et al. Long-term effects of betamethasone on fetal development. Am J Obstet Gynecol. 1981;141:1053\u201364.","journal-title":"Am J Obstet Gynecol"},{"key":"142_CR18","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1006\/hbeh.1994.1030","volume":"28","author":"H Uno","year":"1994","unstructured":"Uno H, Eisele S, Sakai A, Shelton S, Baker E, DeJesus O, et al. Neurotoxicity of glucocorticoids in the primate brain. Horm Behav. 1994;28:336\u201348.","journal-title":"Horm Behav"},{"key":"142_CR19","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1067\/mcp.2002.120250","volume":"71","author":"P Ballabh","year":"2002","unstructured":"Ballabh P, Lo ES, Kumari J, Cooper TB, Zervoudakis I, Auld PA, et al. Pharmacokinetics of betamethasone in twin and singleton pregnancy. Clin Pharmacol Ther. 2002;71:39\u201345.","journal-title":"Clin Pharmacol Ther"},{"key":"142_CR20","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00000542-196507000-00004","volume":"26","author":"JA Pritchard","year":"1965","unstructured":"Pritchard JA. Changes in the blood volume during pregnancy and delivery. Anesthesiology. 1965;26:393\u20139.","journal-title":"Anesthesiology"},{"key":"142_CR21","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1007\/s11095-008-9787-9","volume":"25","author":"S Sahin","year":"2008","unstructured":"Sahin S, Benet LZ. The operational multiple dosing half-life: a key to defining drug accumulation in patients and to designing extended release dosage forms. Pharm Res. 2008;25:2869\u201377.","journal-title":"Pharm Res"},{"key":"142_CR22","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1053\/beog.2001.0231","volume":"15","author":"M Dawes","year":"2001","unstructured":"Dawes M, Chowienczyk PJ. Drugs in pregnancy. Pharmacokinetics in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2001;15:819\u201326.","journal-title":"Best Pract Res Clin Obstet Gynaecol"}],"container-title":["Reproductive Biology and Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12958-016-0142-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T20:29:16Z","timestamp":1654288156000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.rbej.com\/content\/14\/1\/7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,10]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["142"],"URL":"https:\/\/doi.org\/10.1186\/s12958-016-0142-4","relation":{},"ISSN":["1477-7827"],"issn-type":[{"value":"1477-7827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,10]]},"article-number":"7"}}