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This study aims to determine whether EMT affects the incidence of obstetric complications in fresh IVF\/ICSI-embryo transfer (ET) cycles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study collecting a total of 9266 women who had singleton livebirths after fresh IVF\/ICSI-ET treatment cycles at the Center for Reproductive Medicine Affiliated to Shandong University between January 2014 and December 2018. The women were divided into three groups according to the EMT: 544 women with an EMT \u22648\u2009mm, 6234 with an EMT &gt;\u20098\u201312\u2009mm, and 2488 with an EMT &gt;\u200912\u2009mm. The primary outcomes were the incidence of obstetric complications including hypertensive disorders of pregnancy (HDP), gestational diabetes mellitus (GDM), placental abruption, placenta previa, postpartum hemorrhage (PPH) and cesarean section. Multivariable logistic regression analysis was performed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for associations between the EMT measured on the day of human chorionic gonadotropin (HCG) trigger and the risk of the outcomes of interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The HDP incidence rate of pregnant women was highest in EMT\u2009\u2264\u20098\u2009mm group and significantly higher than those in EMT from &gt;\u20098\u201312\u2009mm and EMT &gt;\u200912\u2009mm group, respectively (6.8% versus 3.6 and 3.5%, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001). After adjustment for confounding variables by multivariate logistic regression analysis, a thin EMT was still statistically significant associated with an increased risk of HDP. Compared with women with an EMT &gt;\u20098\u201312\u2009mm, women with an EMT \u22648\u2009mm had an increased risk of HDP (aOR\u2009=\u20091.853, 95% CI 1.281\u20132.679,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A thin endometrium (\u22648\u2009mm) was found to be associated with an increased risk of HDP after adjustment for confounding variables, indicating that the thin endometrium itself is a risk factor for HDP. Obstetricians should remain aware of the possibility of HDP when women with a thin EMT achieve pregnancy through fresh IVF\/ICSI\u2013ET treatment cycles.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12958-021-00738-9","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T03:03:35Z","timestamp":1617937415000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Thin endometrium is associated with the risk of hypertensive disorders of pregnancy in fresh IVF\/ICSI embryo transfer cycles: a retrospective cohort study of 9,266 singleton births"],"prefix":"10.1186","volume":"19","author":[{"given":"Xiaojie","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhao","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4355-8365","authenticated-orcid":false,"given":"Shanshan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"issue":"8","key":"738_CR1","first-page":"Cd010537","volume":"8","author":"C Farquhar","year":"2018","unstructured":"Farquhar C, Marjoribanks J. 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