{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T21:17:33Z","timestamp":1793481453748,"version":"4.5.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod Biol Endocrinol"],"DOI":"10.1186\/s12958-024-01327-2","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T09:42:04Z","timestamp":1737538924000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A cycle-based model to predict no usable blastocyst formation following cycles of in vitro fertilization in patients with normal ovarian reserve"],"prefix":"10.1186","volume":"23","author":[{"given":"Xue","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-yue","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui-lian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-di","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"issue":"11","key":"1327_CR1","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1056\/NEJMoa053524","volume":"354","author":"EG Papanikolaou","year":"2006","unstructured":"Papanikolaou EG, Camus M, Kolibianakis EM, Van Landuyt L, Van Steirteghem A, Devroey P. In vitro fertilization with single blastocyst-stage versus single cleavage-stage embryos. N Engl J Med. 2006;354(11):1139\u201346. https:\/\/doi.org\/10.1056\/NEJMoa053524.","journal-title":"N Engl J Med"},{"issue":"5","key":"1327_CR2","doi-asserted-by":"publisher","first-page":"CD002118","DOI":"10.1002\/14651858.CD002118.pub6","volume":"5","author":"D Glujovsky","year":"2022","unstructured":"Glujovsky D, Quinteiro Retamar AM, Alvarez Sedo CR, Ciapponi A, Cornelisse S, Blake D. Cleavage-stage versus blastocyst-stage embryo transfer in assisted reproductive technology. Cochrane Database Syst Rev. 2022;5(5):CD002118. https:\/\/doi.org\/10.1002\/14651858.CD002118.pub6.","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl 1","key":"1327_CR3","doi-asserted-by":"publisher","first-page":"i72","DOI":"10.1093\/humrep\/des230","volume":"27","author":"T Hardarson","year":"2012","unstructured":"Hardarson T, Van Landuyt L, Jones G. The blastocyst. Hum Reprod. 2012;27(Suppl 1):i72\u201391.","journal-title":"Hum Reprod"},{"key":"1327_CR4","doi-asserted-by":"publisher","first-page":"13499","DOI":"10.1038\/s41598-021-92902-9","volume":"11","author":"R Sainte-Rose","year":"2021","unstructured":"Sainte-Rose R, Petit C, Dijols L, et al. Extended embryo culture is effective for patients of an advanced maternal age. Sci Rep. 2021;11:13499. https:\/\/doi.org\/10.1038\/s41598-021-92902-9.","journal-title":"Sci Rep"},{"issue":"1","key":"1327_CR5","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1093\/humrep\/dem339","volume":"23","author":"EG Papanikolaou","year":"2008","unstructured":"Papanikolaou EG, Kolibianakis EM, Tournaye H, et al. Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis. Hum Reprod. 2008;23(1):91\u20139. https:\/\/doi.org\/10.1093\/humrep\/dem339.","journal-title":"Hum Reprod"},{"issue":"1","key":"1327_CR6","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s10815-019-01621-8","volume":"37","author":"J Deng","year":"2020","unstructured":"Deng J, Zhao Q, Cinnioglu C, Kayali R, Lathi RB, Behr B. The impact of culture conditions on blastocyst formation and aneuploidy rates: a comparison between single-step and sequential media in a large academic practice. J Assist Reprod Genet. 2020;37(1):161\u20139. https:\/\/doi.org\/10.1007\/s10815-019-01621-8.","journal-title":"J Assist Reprod Genet"},{"issue":"2","key":"1327_CR7","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.fertnstert.2009.03.051","volume":"94","author":"MR Thomas","year":"2010","unstructured":"Thomas MR, Sparks AE, Ryan GL, Van Voorhis BJ. Clinical predictors of human blastocyst formation and pregnancy after extended embryo culture and transfer. Fertil Steril. 2010;94(2):543\u20138. https:\/\/doi.org\/10.1016\/j.fertnstert.2009.03.051.","journal-title":"Fertil Steril"},{"issue":"6","key":"1327_CR8","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1093\/humrep\/der037","volume":"26","author":"Alpha Scientists in Reproductive Me","year":"2011","unstructured":"Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod. 2011;26(6):1270\u201383.","journal-title":"Hum Reprod"},{"issue":"1\u20132","key":"1327_CR9","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/s0165-0378(01)00136-x","volume":"55","author":"DK Gardner","year":"2002","unstructured":"Gardner DK, Lane M, Schoolcraft WB. Physiology and culture of the human blastocyst. J Reprod Immunol. 2002;55(1\u20132):85\u2013100. https:\/\/doi.org\/10.1016\/s0165-0378(01)00136-x.","journal-title":"J Reprod Immunol"},{"issue":"4","key":"1327_CR10","doi-asserted-by":"publisher","first-page":"e173","DOI":"10.1016\/S1470-2045(14)71116-7","volume":"16","author":"VP Balachandran","year":"2015","unstructured":"Balachandran VP, Gonen M, Smith JJ, DeMatteo RP. Nomograms in oncology: more than meets the eye. Lancet Oncol. 2015;16(4):e173\u201380. https:\/\/doi.org\/10.1016\/S1470-2045(14)71116-7.","journal-title":"Lancet Oncol"},{"key":"1327_CR11","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/S0895-4356(01)00341-9","volume":"54","author":"EW Steyerberg","year":"2001","unstructured":"Steyerberg EW, Harrell FE Jr, Borsboom GJ, Eijkemans MJ, Vergouwe Y, Habbema JD. Internal validation of predictive models: efficiency of some procedures for logistic regression analysis. J Clin Epidemiol. 2001;54:774\u201381.","journal-title":"J Clin Epidemiol"},{"key":"1327_CR12","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1001\/jama.2017.12126","volume":"318","author":"AC Alba","year":"2017","unstructured":"Alba AC, Agoritsas T, Walsh M, Hanna S, Iorio A, Devereaux PJ, et al. Discrimination and calibration of clinical prediction models: users\u2019 guides to the medical literature. JAMA. 2017;318:1377\u201384. https:\/\/doi.org\/10.1001\/jama.2017.12126.","journal-title":"JAMA"},{"issue":"3","key":"1327_CR13","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.fertnstert.2010.05.042","volume":"94","author":"C Racowsky","year":"2010","unstructured":"Racowsky C, Vernon M, Mayer J, et al. Standardization of grading embryo morphology. Fertil Steril. 2010;94(3):1152\u20133. https:\/\/doi.org\/10.1016\/j.fertnstert.2010.05.042.","journal-title":"Fertil Steril"},{"issue":"12","key":"1327_CR14","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1093\/humrep\/dez210","volume":"34","author":"T Sanchez","year":"2019","unstructured":"Sanchez T, Venturas M, Aghvami SA, et al. Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment. Hum Reprod. 2019;34(12):2349\u201361. https:\/\/doi.org\/10.1093\/humrep\/dez210.","journal-title":"Hum Reprod"},{"issue":"5","key":"1327_CR15","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1093\/humrep\/dead063","volume":"38","author":"M Venturas","year":"2023","unstructured":"Venturas M, Yang X, Sakkas D, Needleman D. Noninvasive metabolic profiling of cumulus cells, oocytes, and embryos via fluorescence lifetime imaging microscopy: a mini-review. Hum Reprod. 2023;38(5):799\u2013810. https:\/\/doi.org\/10.1093\/humrep\/dead063.","journal-title":"Hum Reprod"},{"key":"1327_CR16","doi-asserted-by":"publisher","unstructured":"Armstrong S, Bhide P, Jordan V, Pacey A, Marjoribanks J, Farquhar C. Time-lapse systems for embryo incubation and assessment in assisted reproduction. Cochrane Database Syst Rev. 2019;5(5):CD011320. https:\/\/doi.org\/10.1002\/14651858.CD011320.pub4","DOI":"10.1002\/14651858.CD011320.pub4"},{"key":"1327_CR17","doi-asserted-by":"publisher","unstructured":"Kirkegaard K, Kesmodel US, Hindkj\u00e6r JJ, Ingerslev HJ. Time-lapse parameters as predictors of blastocyst development and pregnancy outcome in embryos from good prognosis patients: a prospective cohort study. Hum Reprod. October 2013;28(10):2643\u201351. https:\/\/doi.org\/10.1093\/humrep\/det300.","DOI":"10.1093\/humrep\/det300"},{"issue":"3","key":"1327_CR18","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/s0015-0282(99)00565-8","volume":"73","author":"C Racowsky","year":"2000","unstructured":"Racowsky C, Jackson KV, Cekleniak NA, Fox JH, Hornstein MD, Ginsburg ES. The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer. Fertil Steril. 2000;73(3):558\u201364. https:\/\/doi.org\/10.1016\/s0015-0282(99)00565-8.","journal-title":"Fertil Steril"},{"key":"1327_CR19","doi-asserted-by":"publisher","first-page":"751373","DOI":"10.3389\/fendo.2021.751373","volume":"12","author":"H Jin","year":"2021","unstructured":"Jin H, Shen X, Song W, Liu Y, Qi L, Zhang F. The development of Nomograms to Predict Blastulation Rate following cycles of in Vitro fertilization in patients with Tubal factor infertility, polycystic ovary syndrome, or endometriosis. Front Endocrinol (Lausanne). 2021;12:751373. https:\/\/doi.org\/10.3389\/fendo.2021.751373.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"1327_CR20","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1093\/humrep\/dep439","volume":"25","author":"L Dessolle","year":"2010","unstructured":"Dessolle L, Fr\u00e9our T, Barri\u00e8re P, et al. A cycle-based model to predict blastocyst transfer cancellation. Hum Reprod. 2010;25(3):598\u2013604. https:\/\/doi.org\/10.1093\/humrep\/dep439.","journal-title":"Hum Reprod"},{"issue":"13 Suppl","key":"1327_CR21","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.1002\/cncr.24352","volume":"115","author":"K Touijer","year":"2009","unstructured":"Touijer K, Scardino PT. Nomograms for staging, prognosis, and predicting treatment outcomes. Cancer. 2009;115(13 Suppl):3107\u201311. https:\/\/doi.org\/10.1002\/cncr.24352.","journal-title":"Cancer"},{"key":"1327_CR22","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1053\/suro.2002.32936","volume":"20","author":"JA Eastham","year":"2002","unstructured":"Eastham JA, Kattam MW, Scardino PT. Nomograms as predictive models. Semin Urol Oncol. 2002;20:108\u201315.","journal-title":"Semin Urol Oncol"},{"key":"1327_CR23","doi-asserted-by":"publisher","first-page":"e074819","DOI":"10.1136\/bmj-2023-074819","volume":"384","author":"GS Collins","year":"2024","unstructured":"Collins GS, Dhiman P, Ma J, et al. Evaluation of clinical prediction models (part 1): from development to external validation. BMJ. 2024;384:e074819. https:\/\/doi.org\/10.1136\/bmj-2023-074819.","journal-title":"BMJ"},{"key":"1327_CR24","doi-asserted-by":"publisher","first-page":"n2134","DOI":"10.1136\/bmj.n2134","volume":"374","author":"RC Slieker","year":"2021","unstructured":"Slieker RC, van der Heijden AAWA, Siddiqui MK, et al. Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study. BMJ. 2021;374:n2134. https:\/\/doi.org\/10.1136\/bmj.n2134.","journal-title":"BMJ"}],"container-title":["Reproductive Biology and Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12958-024-01327-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12958-024-01327-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12958-024-01327-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T09:42:06Z","timestamp":1737538926000},"score":1,"resource":{"primary":{"URL":"https:\/\/rbej.biomedcentral.com\/articles\/10.1186\/s12958-024-01327-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,22]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1327"],"URL":"https:\/\/doi.org\/10.1186\/s12958-024-01327-2","relation":{},"ISSN":["1477-7827"],"issn-type":[{"value":"1477-7827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,22]]},"assertion":[{"value":"6 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for the study was obtained from the Reproductive Medicine Ethics Committee of Henan Provincial People\u2019s Hospital committees (No: SYSZ-LL-2021091501), China. The procedures followed were in accordance with the ethical standards of the Declaration of Helsinki of the World Medical Association.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The Reproductive Medicine Ethics Committee of Henan Provincial People\u2019s Hospital committees waived the need for obtaining informed consent from the participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"11"}}