{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T16:40:48Z","timestamp":1774975248771,"version":"3.50.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":35,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Thrombosis J"],"DOI":"10.1186\/s12959-026-00846-9","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T15:36:44Z","timestamp":1771947404000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multifactorial thrombotic risk in Evans syndrome: a case report and review of the literature"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3791-9157","authenticated-orcid":false,"given":"Hande Nur","family":"Erolmez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Semih","family":"Eker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2219-7049","authenticated-orcid":false,"given":"Fakiha","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1806-2261","authenticated-orcid":false,"given":"Ayse Nilgun","family":"Kul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0774-2766","authenticated-orcid":false,"given":"Gulbuz","family":"Sezgin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3465-2499","authenticated-orcid":false,"given":"Jawed","family":"Fareed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3060-721X","authenticated-orcid":false,"given":"Bulent","family":"Kantarcioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"846_CR1","doi-asserted-by":"publisher","first-page":"109109","DOI":"10.1016\/j.thromres.2024.109109","volume":"241","author":"A -Saldanha","year":"2024","unstructured":"Saldanha A, Colella MP, Villa\u00e7a PR, Thachil J, Orsi FA. The immune thrombocytopenia paradox: should we be concerned about thrombosis in ITP? Thromb Res. 2024;241:109109.","journal-title":"Thromb Res"},{"issue":"1","key":"846_CR2","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/ajh.24234","volume":"91","author":"F -Rodeghiero","year":"2016","unstructured":"Rodeghiero F. Is ITP a thrombophilic disorder? Am J Hematol. 2016;91(1):39\u201345.","journal-title":"Am J Hematol"},{"issue":"8","key":"846_CR3","doi-asserted-by":"publisher","first-page":"e617","DOI":"10.1016\/S2352-3026(24)00144-3","volume":"11","author":"B -Fattizzo","year":"2024","unstructured":"Fattizzo B, Marchetti M, Michel M, Cantoni S, Frederiksen H, Giordano G, Glenth\u00f8j A, Gonz\u00e1lez-L\u00f3pez TJ, Murakhovskaya I, Napolitano M, Mingot ME, Arguello M, Patriarca A, Raso S, Vianelli N, Barcellini W. Diagnosis and management of Evans syndrome in adults: first consensus recommendations. Lancet Haematol. 2024;11(8):e617\u201328.","journal-title":"Lancet Haematol"},{"issue":"9","key":"846_CR4","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.3390\/biomedicines9091170","volume":"9","author":"R -Tomasello","year":"2021","unstructured":"Tomasello R, Giordano G, Romano F, et al. Immune thrombocytopenia in antiphospholipid syndrome: is it primary or secondary? Biomedicines. 2021;9(9):1170. Published 2021 Sep 6.","journal-title":"Biomedicines"},{"key":"846_CR5","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.thromres.2022.11.008","volume":"221","author":"D -Fayard","year":"2023","unstructured":"Fayard D, Lobbes H, Pereira B, Ruivard M. Risk of thrombosis associated with antiphospholipid antibodies in immune thrombocytopenic purpura: A single center retrospective study of 152 patients. Thromb Res. 2023;221:7\u20139.","journal-title":"Thromb Res"},{"issue":"6","key":"846_CR6","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1002\/ajh.26900","volume":"98","author":"T -Pincez","year":"2023","unstructured":"Pincez T, Fernandes H, Pasquet M, et al. Impact of age at diagnosis, sex, and immunopathological manifestations in 886 patients with pediatric chronic immune thrombocytopenia. Am J Hematol. 2023;98(6):857\u201368.","journal-title":"Am J Hematol"},{"issue":"12","key":"846_CR7","doi-asserted-by":"publisher","first-page":"4203","DOI":"10.1182\/blood.V84.12.4203.bloodjournal84124203","volume":"84","author":"R -Stasi","year":"1994","unstructured":"Stasi R, Stipa E, Masi M, et al. Prevalence and clinical significance of elevated antiphospholipid antibodies in patients with idiopathic thrombocytopenic purpura. Blood. 1994;84(12):4203\u20138.","journal-title":"Blood"},{"issue":"6","key":"846_CR8","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.1182\/blood.V98.6.1760","volume":"98","author":"R -Diz-K\u00fc\u00e7\u00fckkaya","year":"2001","unstructured":"Diz-K\u00fc\u00e7\u00fckkaya R, Hacihanefio\u011flu A, Yenerel M, et al. Antiphospholipid antibodies and antiphospholipid syndrome in patients presenting with immune thrombocytopenic purpura: a prospective cohort study. Blood. 2001;98(6):1760\u20134.","journal-title":"Blood"},{"issue":"15","key":"846_CR9","doi-asserted-by":"publisher","first-page":"3167","DOI":"10.1182\/blood-2009-04-215368","volume":"114","author":"M -Michel","year":"2009","unstructured":"Michel M, Chanet V, Dechartres A, et al. The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. Blood. 2009;114(15):3167\u201372.","journal-title":"Blood"},{"issue":"10","key":"846_CR10","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1002\/ajh.25574","volume":"94","author":"DL -Hansen","year":"2019","unstructured":"Hansen DL, M\u00f6ller S, Andersen K, Gaist D, Frederiksen H. Evans syndrome in adults - incidence, prevalence, and survival in a nationwide cohort. Am J Hematol. 2019;94(10):1081\u201390.","journal-title":"Am J Hematol"},{"issue":"4","key":"846_CR11","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.jbspin.2011.07.004","volume":"79","author":"GL -Costallat","year":"2012","unstructured":"Costallat GL, Appenzeller S, Costallat LT. Evans syndrome and systemic lupus erythematosus: clinical presentation and outcome. Joint Bone Spine. 2012;79(4):362\u20134.","journal-title":"Joint Bone Spine"},{"issue":"15","key":"846_CR12","doi-asserted-by":"publisher","first-page":"e3279","DOI":"10.1097\/MD.0000000000003279","volume":"95","author":"L -Zhang","year":"2016","unstructured":"Zhang L, Wu X, Wang L, et al. Clinical features of systemic lupus erythematosus patients complicated with Evans syndrome: A Case-Control, single center study. Med (Baltim). 2016;95(15):e3279.","journal-title":"Med (Baltim)"},{"issue":"19","key":"846_CR13","doi-asserted-by":"publisher","first-page":"2930","DOI":"10.1182\/blood-2014-06-583021","volume":"124","author":"W -Barcellini","year":"2014","unstructured":"Barcellini W, Fattizzo B, Zaninoni A, et al. Clinical heterogeneity and predictors of outcome in primary autoimmune hemolytic anemia: a GIMEMA study of 308 patients. Blood. 2014;124(19):2930\u20136.","journal-title":"Blood"},{"issue":"11","key":"846_CR14","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1016\/j.autrev.2015.07.001","volume":"14","author":"M -Lecouffe-Desprets","year":"2015","unstructured":"Lecouffe-Desprets M, N\u00e9el A, Graveleau J, et al. Venous thromboembolism related to warm autoimmune hemolytic anemia: a case-control study. Autoimmun Rev. 2015;14(11):1023\u20138.","journal-title":"Autoimmun Rev"},{"issue":"24","key":"846_CR15","doi-asserted-by":"publisher","first-page":"5468","DOI":"10.1182\/bloodadvances.2021005610","volume":"5","author":"B -Fattizzo","year":"2021","unstructured":"Fattizzo B, Michel M, Giannotta JA, et al. Evans syndrome in adults: an observational multicenter study. Blood Adv. 2021;5(24):5468\u201378.","journal-title":"Blood Adv"},{"key":"846_CR16","doi-asserted-by":"publisher","first-page":"79","DOI":"10.21037\/acr-24-190","volume":"9","author":"S -Singh","year":"2025","unstructured":"Singh S, Candiales SA, Hunzeker Z, Freites CO, Idowu M. Thrombotic storm with antiphospholipid syndrome in the setting of relapsing Evans syndrome and systemic lupus erythematosus: a case report. AME Case Rep. 2025;9:79. Published 2025 Jul 15.","journal-title":"AME Case Rep"},{"key":"846_CR17","doi-asserted-by":"crossref","unstructured":"Matsushita K, Nagayoshi Y, Yoshii R, et al. Rituximab as an effective treatment for new-onset Evans syndrome and systemic lupus erythematosus with lupus nephritis. Intern Med. 2025 Mar 15.","DOI":"10.2169\/internalmedicine.4871-24"},{"issue":"7","key":"846_CR18","first-page":"004592","volume":"11","author":"T -Takahashi","year":"2024","unstructured":"Takahashi T, Takaoka K, Kwong K, et al. The successful management of stroke in Evans syndrome by anticoagulation with Warfarin, intravenous Immunoglobulin (IVIG), and High-Dose corticosteroid. Eur J Case Rep Intern Med. 2024;11(7):004592. Published 2024 Jun 28.","journal-title":"Eur J Case Rep Intern Med"},{"issue":"7","key":"846_CR19","first-page":"e63992","volume":"16","author":"O -Abdelhalim","year":"2024","unstructured":"Abdelhalim O, Serna C, Guerrero N, Onasis I, Abosheaishaa H. Secondary Evans syndrome presenting with lupus anticoagulant. Cureus. 2024;16(7):e63992. Published 2024 Jul 6.","journal-title":"Cureus"},{"issue":"12","key":"846_CR20","doi-asserted-by":"publisher","first-page":"6323","DOI":"10.1016\/j.radcr.2024.09.053","volume":"19","author":"HT -Hashim","year":"2024","unstructured":"Hashim HT, Al-Obaidi AD, Al-Fatlawi N, et al. Evans syndrome in conjunction with rheumatoid arthritis and SLE: A unique case of autoimmune intersection. Radiol Case Rep. 2024;19(12):6323\u20137. Published 2024 Sep 25.","journal-title":"Radiol Case Rep"},{"issue":"7","key":"846_CR21","first-page":"1147","volume":"60","author":"HJ -Nam","year":"2024","unstructured":"Nam HJ, Kim SY, Byeon JY, Choi HJ. Extremely rare case of successful treatment of foot ulcer associated with evans\u2019 syndrome and buerger\u2019s disease. Med (Kaunas). 2024;60(7):1147. Published 2024 Jul 16.","journal-title":"Med (Kaunas)"},{"issue":"12","key":"846_CR22","first-page":"005015","volume":"11","author":"C -Porcu","year":"2024","unstructured":"Porcu C, Merkel N, Fusi-Schimdhauser T. Budd-Chiari syndrome as an initial manifestation of incomplete systemic lupus erythematosus. Eur J Case Rep Intern Med. 2024;11(12):005015. Published 2024 Dec 2.","journal-title":"Eur J Case Rep Intern Med"},{"issue":"12","key":"846_CR23","doi-asserted-by":"publisher","first-page":"333102423121947","DOI":"10.1177\/03331024231219477","volume":"43","author":"T -Tezuka","year":"2023","unstructured":"Tezuka T, Shibata M, Hanaoka H, et al. Systemic lupus erythematosus mimicking retinal migraine: a case report. Cephalalgia. 2023;43(12):3331024231219477.","journal-title":"Cephalalgia"},{"issue":"3","key":"846_CR24","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1007\/s12185-021-03243-2","volume":"115","author":"D -Hidaka","year":"2022","unstructured":"Hidaka D, Ogasawara R, Sugimura S, et al. New-onset Evans syndrome associated with systemic lupus erythematosus after BNT162b2 mRNA COVID-19 vaccination. Int J Hematol. 2022;115(3):424\u20137.","journal-title":"Int J Hematol"},{"issue":"33","key":"846_CR25","doi-asserted-by":"publisher","first-page":"e27009","DOI":"10.1097\/MD.0000000000027009","volume":"100","author":"YC -Yang","year":"2021","unstructured":"Yang YC, Chen YY. Right heart thrombus-in-transit in a patient with Evans syndrome: A case report. Med (Baltim). 2021;100(33):e27009.","journal-title":"Med (Baltim)"},{"key":"846_CR26","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.thromres.2021.02.021","volume":"208","author":"R -Diez-Feij\u00f3o","year":"2021","unstructured":"Diez-Feij\u00f3o R, Rodr\u00edguez-Sevilla JJ, Colomo L, et al. Massive intrasplenic arterial thrombosis in a patient with chronic ITP during the development of an Evans syndrome. Thromb Res. 2021;208:226\u20139.","journal-title":"Thromb Res"},{"issue":"7","key":"846_CR27","first-page":"e16658","volume":"13","author":"M -Rutherford","year":"2021","unstructured":"Rutherford M, Tran M, Salazar L, Iqbal F, Mazharuddin A, Camarena J. An uncharacteristic presentation of Evans syndrome following treatment with dupilumab. Cureus. 2021;13(7):e16658. Published 2021 Jul 27.","journal-title":"Cureus"},{"issue":"4","key":"846_CR28","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.htct.2020.08.003","volume":"42","author":"J -Zarza","year":"2020","unstructured":"Zarza J, Von Horoch J, Aguayo N, B\u00e1ez E. Evans syndrome associated with antiphospholipid antibodies in a patient with SARS-COV-2 infection. Hematol Transfus Cell Ther. 2020;42(4):309\u201312.","journal-title":"Hematol Transfus Cell Ther"},{"issue":"2","key":"846_CR29","doi-asserted-by":"publisher","first-page":"e59","DOI":"10.1111\/bjh.16846","volume":"190","author":"M -Li","year":"2020","unstructured":"Li M, Nguyen CB, Yeung Z, Sanchez K, Rosen D, Bushan S. Evans syndrome in a patient with COVID-19. Br J Haematol. 2020;190(2):e59\u201361.","journal-title":"Br J Haematol"},{"issue":"2","key":"846_CR30","first-page":"e6845","volume":"12","author":"BP -Patel","year":"2020","unstructured":"Patel BP, Jakob J. A rare case of simultaneous Evans syndrome and primary antiphospholipid syndrome. Cureus. 2020;12(2):e6845. Published 2020 Feb 1.","journal-title":"Cureus"},{"issue":"12","key":"846_CR31","doi-asserted-by":"publisher","first-page":"2513","DOI":"10.1002\/ccr3.2550","volume":"7","author":"L -Stolyar","year":"2019","unstructured":"Stolyar L, Rizi B, Lin S, Hsieh E. Systemic lupus erythematosus presenting as Evans syndrome. Clin Case Rep. 2019;7(12):2513\u20134. Published 2019 Nov 18.","journal-title":"Clin Case Rep"},{"key":"846_CR32","doi-asserted-by":"crossref","unstructured":"Monga V, Maliske SM, Perepu U. Fatal pulmonary embolism following splenectomy in a patient with Evan\u2019s syndrome: case report and review of the literature. Thromb J. 2017;15:18.","DOI":"10.1186\/s12959-017-0141-5"},{"issue":"4","key":"846_CR33","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.bjhh.2015.03.002","volume":"37","author":"JC -Jaime-P\u00e9rez","year":"2015","unstructured":"Jaime-P\u00e9rez JC, Guerra-Leal LN, L\u00f3pez-Razo ON, M\u00e9ndez-Ram\u00edrez N, G\u00f3mez-Almaguer D. Experience with Evans syndrome in an academic referral center. Rev Bras Hematol Hemoter. 2015;37(4):230\u20135.","journal-title":"Rev Bras Hematol Hemoter"},{"issue":"Suppl 2","key":"846_CR34","doi-asserted-by":"publisher","first-page":"S280","DOI":"10.1016\/j.ihj.2015.11.041","volume":"68","author":"F -Kizilirmak","year":"2016","unstructured":"Kizilirmak F, Demir GG, Cakal B, Bekoz HS, Olgun FE. Evans syndrome with non-ST segment elevation myocardial infarction complicated by hemopericardium. Indian Heart J. 2016;68(Suppl 2):S280\u20133.","journal-title":"Indian Heart J"},{"issue":"6","key":"846_CR35","first-page":"9590","volume":"8","author":"Y -Zhang","year":"2015","unstructured":"Zhang Y, Zheng K, Zheng M, Liu Q, Meng L. The positive therapeutic effect in a patient of Evans syndrome combined with acute myocardial infarction. Int J Clin Exp Med. 2015;8(6):9590\u20134. Published 2015 Jun 15.","journal-title":"Int J Clin Exp Med"},{"issue":"11","key":"846_CR36","doi-asserted-by":"publisher","first-page":"e7","DOI":"10.1016\/j.amjmed.2013.05.026","volume":"126","author":"R -Ghashghaei","year":"2013","unstructured":"Ghashghaei R, Popa R, Shen J. Evans syndrome. Am J Med. 2013;126(11):e7\u20138.","journal-title":"Am J Med"},{"issue":"7","key":"846_CR37","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1097\/MBC.0b013e32830d5ef5","volume":"19","author":"R -Escher","year":"2008","unstructured":"Escher R. Extensive venous thrombosis following administration of high-dose glucocorticosteroids and Tranexamic acid in relapsed Evans syndrome. Blood Coagul Fibrinolysis. 2008;19(7):741\u20132.","journal-title":"Blood Coagul Fibrinolysis"},{"issue":"8","key":"846_CR38","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1177\/0961203307087876","volume":"17","author":"A -R\u00fcckert","year":"2008","unstructured":"R\u00fcckert A, Glimm H, L\u00fcbbert M, Gr\u00fcllich C. Successful treatment of life-threatening Evans syndrome due to antiphospholipid antibody syndrome by rituximab-based regimen: a case with long-term follow-up. Lupus. 2008;17(8):757\u201360.","journal-title":"Lupus"},{"issue":"2","key":"846_CR39","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1007\/s00277-004-0963-7","volume":"84","author":"S -Yilmaz","year":"2005","unstructured":"Yilmaz S, Oren H, Irken G, T\u00fcrker M, Yilmaz E, Ada E. Cerebral venous thrombosis in a patient with Evans syndrome: a rare association. Ann Hematol. 2005;84(2):124\u20136.","journal-title":"Ann Hematol"},{"issue":"11","key":"846_CR40","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1136\/ard.59.11.920","volume":"59","author":"J -Font","year":"2000","unstructured":"Font J, Jim\u00e9nez S, Cervera R, et al. Splenectomy for refractory evans\u2019 syndrome associated with antiphospholipid antibodies: report of two cases. Ann Rheum Dis. 2000;59(11):920\u20133.","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"846_CR41","doi-asserted-by":"publisher","first-page":"168","DOI":"10.5144\/0256-4947.1995.168","volume":"15","author":"FZ -Al-Fiar","year":"1995","unstructured":"Al-Fiar FZ, Clink HM. Evans syndrome associated with venous thrombosis. Ann Saudi Med. 1995;15(2):168\u201370.","journal-title":"Ann Saudi Med"},{"issue":"23","key":"846_CR42","doi-asserted-by":"publisher","first-page":"4782","DOI":"10.1182\/blood-2012-12-467068","volume":"121","author":"S -Boyle","year":"2013","unstructured":"Boyle S, White RH, Brunson A, Wun T. Splenectomy and the incidence of venous thromboembolism and sepsis in patients with immune thrombocytopenia. Blood. 2013;121(23):4782\u201390.","journal-title":"Blood"},{"issue":"2","key":"846_CR43","doi-asserted-by":"publisher","first-page":"392","DOI":"10.3324\/haematol.2013.092460","volume":"99","author":"SY -Kristinsson","year":"2014","unstructured":"Kristinsson SY, Gridley G, Hoover RN, Check D, Landgren O. Long-term risks after splenectomy among 8,149 cancer-free American veterans: a cohort study with up to 27 years follow-up. Haematologica. 2014;99(2):392\u20138.","journal-title":"Haematologica"},{"issue":"3","key":"846_CR44","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1111\/bjh.17709","volume":"195","author":"M -Lafaurie","year":"2021","unstructured":"Lafaurie M, Maquet J, Baricault B, et al. Risk factors of hospitalisation for thrombosis in adults with primary immune thrombocytopenia, including disease-specific treatments: a French nationwide cohort study. Br J Haematol. 2021;195(3):456\u201365.","journal-title":"Br J Haematol"},{"issue":"7","key":"846_CR45","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1182\/blood.2022016818","volume":"140","author":"B -Fattizzo","year":"2022","unstructured":"Fattizzo B, Cecchi N, Bortolotti M, et al. Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience. Blood. 2022;140(7):789\u201392. https:\/\/doi.org\/10.1182\/blood.2022016818.","journal-title":"Blood"},{"issue":"6","key":"846_CR46","doi-asserted-by":"publisher","first-page":"423","DOI":"10.3109\/09537104.2011.634931","volume":"23","author":"S -Gudbrandsdottir","year":"2012","unstructured":"Gudbrandsdottir S, Frederiksen H, Hasselbalch H. Thrombopoietin-receptor agonists in haematological disorders: the Danish experience. Platelets. 2012;23(6):423\u20139.","journal-title":"Platelets"},{"issue":"10","key":"846_CR47","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1136\/annrheumdis-2019-215213","volume":"78","author":"MG -Tektonidou","year":"2019","unstructured":"Tektonidou MG, Andreoli L, Limper M, et al. EULAR recommendations for the management of antiphospholipid syndrome in adults. Ann Rheum Dis. 2019;78(10):1296\u2013304.","journal-title":"Ann Rheum Dis"},{"issue":"13","key":"846_CR48","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1182\/blood-2018-04-848333","volume":"132","author":"V -Pengo","year":"2018","unstructured":"Pengo V, Denas G, Zoppellaro G, et al. Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome. Blood. 2018;132(13):1365\u201371.","journal-title":"Blood"}],"container-title":["Thrombosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12959-026-00846-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12959-026-00846-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12959-026-00846-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T15:03:43Z","timestamp":1774969423000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12959-026-00846-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,24]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["846"],"URL":"https:\/\/doi.org\/10.1186\/s12959-026-00846-9","relation":{},"ISSN":["1477-9560"],"issn-type":[{"value":"1477-9560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,24]]},"assertion":[{"value":"6 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not appliable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report, and any patient-identifying information has been removed from the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"36"}}