{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:13:15Z","timestamp":1770509595028,"version":"3.49.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Popul Health Metrics"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12963-017-0135-3","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T16:41:55Z","timestamp":1495125715000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Multiple cause-of-death data among people with AIDS in Italy: a nationwide cross-sectional study"],"prefix":"10.1186","volume":"15","author":[{"given":"Enrico","family":"Grande","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Zucchetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Suligoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Grippo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilena","family":"Pappagallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saverio","family":"Virdone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Camoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Taborelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenza","family":"Regine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Serraino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Frova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"issue":"Suppl 1","key":"135_CR1","first-page":"9","volume":"29","author":"M Raimondo","year":"2016","unstructured":"Raimondo M, Boros S, Regine V, Pugliese L, Santaquilani M, Ferri M, et al. Aggiornamento delle nuove diagnosi di infezione da HIV e dei casi di AIDS in Italia al 31 dicembre 2015. Not Ist Super Sanit\u00e0. 2016;29 Suppl 1:9.","journal-title":"Not Ist Super Sanit\u00e0"},{"key":"135_CR2","doi-asserted-by":"publisher","first-page":"209619","DOI":"10.1155\/2014\/209619","volume":"2014","author":"L Camoni","year":"2014","unstructured":"Camoni L, Regine V, Stanecki K, Salfa MC, Raimondo M, Suligoi B. Estimates of the number of people living with HIV in Italy. Biomed Res Int. 2014;2014:209619. doi: 10.1155\/2014\/209619 .","journal-title":"Biomed Res Int"},{"issue":"3","key":"135_CR3","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1089\/AID.2014.0154","volume":"31","author":"L Camoni","year":"2015","unstructured":"Camoni L, Raimondo M, Dorrucci M, Regine V, Salfa MC, Suligoi B, CARPHA Study Group. Estimating minimum adult HIV prevalence: a cross-sectional study to assess the characteristics of people living with HIV in Italy. AIDS Res Hum Retroviruses. 2015;31(3):282\u20137. doi: 10.1089\/AID.2014.0154 .","journal-title":"AIDS Res Hum Retroviruses"},{"key":"135_CR4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0140-6736(08)61113-7","volume":"372","author":"Antiretroviral Therapy Cohort Collaboration","year":"2008","unstructured":"Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. 2008;372:293\u20139.","journal-title":"Lancet"},{"key":"135_CR5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/01.qai.0000233310.90484.16","volume":"43","author":"FJ Palella Jr","year":"2006","unstructured":"Palella Jr FJ, Baker RK, Moorman AC, Chmiel JS, Wood KC, Brooks JT, Holmberg SD. Mortality in the highly active antiretroviral therapy era: Changing causes of death and disease in the HIV Outpatient Study. J Acquir Immune Defic Syndr. 2006;43:27\u201334.","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"10","key":"135_CR6","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1089\/apc.2014.0079","volume":"28","author":"SK Schwarcz","year":"2014","unstructured":"Schwarcz SK, Vu A, Hsu LC, Hessol NA. Changes in causes of death among persons with AIDS: San Francisco, California, 1996\u20132011. AIDS Patient Care STDs. 2014;28(10):517\u201323. doi: 10.1089\/apc.2014.0079 .","journal-title":"AIDS Patient Care STDs"},{"issue":"9939","key":"135_CR7","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S0140-6736(14)60604-8","volume":"384","author":"CJ Smith","year":"2014","unstructured":"Smith CJ, Ryom L, Weber R, Morlat P, Pradier C, Reiss P, Kowalska JD, de Wit S, Law M, el Sadr W, Kirk O, Friis-Moller N, Monforte A, Phillips AN, Sabin CA, Lundgren JD D, A:D Study Group. Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration. Lancet. 2014;384(9939):241\u20138. doi: 10.1016\/S0140-6736(14)60604-8 .","journal-title":"Lancet"},{"key":"135_CR8","doi-asserted-by":"publisher","unstructured":"Vandenhende MA, Roussillon C, Henard S, Morlat P, Oksenhendler E, Aumaitre H, Georget A, May T, Rosenthal E, Salmon D, Cacoub P, Costagliola D, Ch\u00eane G, Bonnet F; ANRS EN20 Mortalit\u00e9 2010 study group. Cancer-Related Causes of Death among HIV-Infected Patients in France in 2010: Evolution since 2000. PLoS One. 2015. doi: 10.1371\/journal.pone.0129550 .","DOI":"10.1371\/journal.pone.0129550"},{"key":"135_CR9","volume-title":"International statistical classification of diseases and related health problems. tenth revision (ICD-10)","author":"World Health Organization","year":"1992","unstructured":"World Health Organization. International statistical classification of diseases and related health problems. tenth revision (ICD-10). Geneva: WHO; 1992."},{"issue":"11","key":"135_CR10","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.2105\/AJPH.72.11.1265","volume":"72","author":"RF Chamblee","year":"1982","unstructured":"Chamblee RF, Evans MC. New dimensions in cause of death statistics. Am J Public Health. 1982;72(11):1265\u201370.","journal-title":"Am J Public Health"},{"issue":"5","key":"135_CR11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s10654-008-9235-5","volume":"23","author":"I Romon","year":"2008","unstructured":"Romon I, Jougla E, Balkau B, Fagot Campagna A. The burden of diabetes-related mortality in France in 2002: an analysis using both underlying and multiple causes of death. Eur J Epidemiol. 2008;23(5):327\u201334.","journal-title":"Eur J Epidemiol"},{"issue":"2","key":"135_CR12","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1177\/0898264313514443","volume":"26","author":"A D\u00e9sesquelles","year":"2014","unstructured":"D\u00e9sesquelles A, Demuru E, Salvatore MA, Pappagallo M, Frova L, Mesl\u00e9 F, Egidi V. Mortality from Alzheimer\u2019s disase, Parkinson\u2019s disease and dementia in France and Italy: a comparison using multiple-cause-of-death approach. J Aging Health. 2014;26(2):283\u2013315.","journal-title":"J Aging Health"},{"issue":"1","key":"135_CR13","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/aje\/kwm037","volume":"166","author":"MD Redelings","year":"2007","unstructured":"Redelings MD, Wise M, Sorvillo F. Using multiple cause-of-death data to investigate associations and causality between conditions listed on the death certificate. Am J Epidemiol. 2007;166(1):104\u20138.","journal-title":"Am J Epidemiol"},{"key":"135_CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/OAMS.S23627","volume":"2","author":"AKA Amey","year":"2012","unstructured":"Amey AKA, Forcheh N, Setlhare K. Multiple causes of death models for human immunodeficiency virus\/acquired immune deficiency syndrome and related mortality in South Africa in 2006 and 2007. Open Access Med Stat. 2012;2:1\u201313.","journal-title":"Open Access Med Stat"},{"key":"135_CR15","doi-asserted-by":"crossref","unstructured":"Whiteside YO, Selik R, An Q, Huang T, Karch D, Hernandez AL, Hall HI: Comparison of Rates of Death Having any Death-Certificate Mention of Heart, Kidney, or Liver Disease Among Persons Diagnosed with HIV Infection with those in the General US Population, 2009\u20132011. Open AIDS J 2015. doi:10.2174\/1874613601509010014.","DOI":"10.2174\/1874613601509010014"},{"issue":"8842","key":"135_CR16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0140-6736(93)93040-8","volume":"341","author":"RA Ancelle Park","year":"1993","unstructured":"Ancelle Park RA. Expanded European AIDS cases definition (letter). Lancet. 1993;341(8842):441.","journal-title":"Lancet"},{"issue":"Suppl 1","key":"135_CR17","first-page":"9","volume":"27","author":"L Camoni","year":"2014","unstructured":"Camoni L, Boros S, Regine V, et al. Aggiornamento delle nuove diagnosi di infezione da HIV e dei casi di AIDS in Italia al 31 dicembre 2013. Not Ist Super Sanit\u00e0. 2014;27 Suppl 1:9.","journal-title":"Not Ist Super Sanit\u00e0"},{"issue":"1","key":"135_CR18","first-page":"12","volume":"8","author":"S Conti","year":"1997","unstructured":"Conti S, Farchi G, Galletti A, Masocco M, Napoli PA, Pezzotti P, Rezza G, Toccaceli V, Cariani G. La notifica della mortalit\u00e0 per AIDS in Italia (1992): qualit\u00e0 della certificazione e sottostima. Giornale Italiano dell\u2019AIDS. 1997;8(1):12\u20136.","journal-title":"Giornale Italiano dell\u2019AIDS"},{"key":"135_CR19","doi-asserted-by":"crossref","unstructured":"Dal Maso L, Braga C, Franceschi S: Methodology Used for \u201cSoftware for Automated Linkage in Italy\u201d (SALI). J Biomed Inform 2001. doi:10.1006\/jbin.2002.1036.","DOI":"10.1006\/jbin.2002.1036"},{"key":"135_CR20","volume-title":"Practical statistics for medical research","author":"DG Altman","year":"1991","unstructured":"Altman DG. Practical statistics for medical research. London: Chapman and Hall; 1991."},{"issue":"9","key":"135_CR21","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1093\/infdis\/jiv235","volume":"212","author":"K Djawe","year":"2015","unstructured":"Djawe K, Buchacz K, Hsu L, Chen MJ, Selik RM, Rose C, Williams T, Brooks JT, Schwarcz S. Mortality risk after AIDS-defining opportunistic illness among HIV-infected persons-San Francisco, 1981\u20132012. J Infect Dis. 2015;212(9):1366\u201375. doi: 10.1093\/infdis\/jiv235 .","journal-title":"J Infect Dis"},{"key":"135_CR22","doi-asserted-by":"crossref","unstructured":"Klein MB, Rollet-Kurhajec KC, Moodie EE, Yaphe S, Tyndall M, Walmsley S, Gill J, Martel-Laferriere V, Cooper C; Canadian Co-infection Cohort Investigators: Mortality in HIV-hepatitis C co-infected patients in Canada compared to the general Canadian population (2003\u20132013). AIDS 2014. doi:10.1097\/QAD.0000000000000377.","DOI":"10.1097\/QAD.0000000000000377"},{"key":"135_CR23","doi-asserted-by":"crossref","unstructured":"Rosenthal E, Roussillon C, Salmon-C\u00e9ron D, Georget A, H\u00e9nard S, Huleux T, Gueit I, Mortier E, Costagliola D, Morlat P, Ch\u00eane G, Cacoub P; Mortalit\u00e9 2010 and GERMIVIC study groups: Liver-related deaths in HIV-infected patients between 1995 and 2010 in France: the Mortavic 2010 study in collaboration with the Agence Nationale de Recherche sur le SIDA (ANRS) EN 20 Mortalit\u00e9 2010 survey. HIV Med 2015. doi:10.1111\/hiv.12204.","DOI":"10.1111\/hiv.12204"},{"key":"135_CR24","doi-asserted-by":"crossref","unstructured":"May MT, Justice AC, Birnie K, Ingle SM, Smit C, Smith C, Neau D, Guiguet M, Schwarze-Zander C, Moreno S, Guest JL, Monforte Ad, Tural C, Gill MJ, Bregenzer A, Kirk O, Saag M, Sterling TR, Crane HM, Sterne JA: Injection Drug Use and Hepatitis C as Risk Factors for Mortality in HIV-Infected Individuals: The Antiretroviral Therapy Cohort Collaboration J Acquir Immune Defic Syndr 2015. doi:10.1097\/QAI.0000000000000603.","DOI":"10.1097\/QAI.0000000000000603"},{"key":"135_CR25","doi-asserted-by":"crossref","unstructured":"Norton B, Naggie S: The clinical management of HCV in the HIV-infected patient. Antivir Ther 2014. doi: 10.3851\/IMP2910.","DOI":"10.3851\/IMP2910"},{"key":"135_CR26","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/QAI.0b013e3181b327ca","volume":"52","author":"MS Shiels","year":"2009","unstructured":"Shiels MS, Cole SR, Kirk GD, Poole C. A Meta-Analysis of the incidence of Non-AIDS cancer in HIV-Infected individuals. J Acquir Immune Defic Syndr. 2009;52:611\u201322.","journal-title":"J Acquir Immune Defic Syndr"},{"key":"135_CR27","doi-asserted-by":"crossref","unstructured":"Robbins HA, Pfeiffer RM, Shiels MS, Li J, Hall HI, Engels EA: Excess cancers among HIV-infected people in the United States. J Natl Cancer Inst 2015. doi:10.1093\/jnci\/dju503.","DOI":"10.1093\/jnci\/dju503"},{"issue":"9","key":"135_CR28","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1086\/656629","volume":"51","author":"A Zucchetto","year":"2010","unstructured":"Zucchetto A, Suligoi B, De Paoli A, Pennazza S, Polesel J, Bruzzone S, Rezza G, De Paoli P, Dal Maso L, Serraino D. Excess mortality for Non\u2013AIDS defining cancers among People with AIDS. Clin Infect Dis. 2010;51(9):1099\u2013101.","journal-title":"Clin Infect Dis"},{"issue":"1","key":"135_CR29","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1182\/blood.V91.1.301","volume":"91","author":"PS Sullivan","year":"1998","unstructured":"Sullivan PS, Hanson DL, Chu SY, Jones JL, Ward JW. Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the multistate adult and adolescent spectrum of HIV disease surveillance project. Blood. 1998;91(1):301\u20138.","journal-title":"Blood"},{"key":"135_CR30","unstructured":"La sorveglianza Passi. I dati per l\u2019Italia. http:\/\/www.epicentro.iss.it\/passi\/dati\/diabete.asp . [Accessed 09 May 2016]."},{"issue":"5","key":"135_CR31","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1097\/QAI.0b013e31819c291b","volume":"50","author":"K Samaras","year":"2009","unstructured":"Samaras K. Prevalence and pathogenesis of diabetes mellitus in HIV-1 infection treated with combined antiretroviral therapy. J Acquir Immune Defic Syndr. 2009;50(5):499\u2013505. doi: 10.1097\/QAI.0b013e31819c291b .","journal-title":"J Acquir Immune Defic Syndr"},{"key":"135_CR32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/nri1527","volume":"5","author":"F Gonzalez-Scarano","year":"2005","unstructured":"Gonzalez-Scarano F, Martin-Garcia J. The neuropathogenesis of AIDS. Nat Rev Immunol. 2005;5:69\u201381.","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"135_CR33","first-page":"54","volume":"17","author":"D Elbirt","year":"2015","unstructured":"Elbirt D, Mahlab-Guri K, Bezalel-Rosenberg S, Gill H, Attali M, Asher I. HIV-associated neurocognitive disorders (HAND). Isr Med Assoc J. 2015;17(1):54\u20139.","journal-title":"Isr Med Assoc J"},{"key":"135_CR34","doi-asserted-by":"crossref","unstructured":"Baker LM, Paul RH, Heaps-Woodruff JM, Chang JY, Ortega M, Margolin Z, Usher C, Basco B, Cooley S, Ances BM: The Effect of Central Nervous System Penetration Effectiveness of Highly Active Antiretroviral Therapy on Neuropsychological Performance and Neuroimaging in HIV Infected Individuals. J Neuroimmune Pharmacol 2015. doi: 10.1007\/s11481-015-9610-4.","DOI":"10.1007\/s11481-015-9610-4"},{"key":"135_CR35","doi-asserted-by":"crossref","unstructured":"Matinella A, Lanzafame M, Bonometti MA, Gajofatto A, Concia E, Vento S, Monaco S, Ferrari S: Neurological complications of HIV infection in pre-HAART and HAART era: a retrospective study. J Neurol 2015. doi:10.1007\/s00415-015-7713-8.","DOI":"10.1007\/s00415-015-7713-8"},{"issue":"5","key":"135_CR36","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1007\/s13365-015-0358-7.32","volume":"21","author":"F Zen\u00f3n","year":"2015","unstructured":"Zen\u00f3n F, Cantres-Rosario Y, Adiga R, Gonzalez M, Rodriguez-Franco E, Langford D, Melendez LM. HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol. 2015;21(5):544\u201358. doi: 10.1007\/s13365-015-0358-7.32 .","journal-title":"J Neurovirol"},{"issue":"2","key":"135_CR37","first-page":"97","volume":"6","author":"E Valencia","year":"2004","unstructured":"Valencia E, Mir\u00f3 J. Endocarditis in the setting of HIV infection. AIDS Rev. 2004;6(2):97\u2013106.","journal-title":"AIDS Rev"},{"issue":"9772","key":"135_CR38","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S0140-6736(10)62001-6","volume":"377","author":"D Joshi","year":"2011","unstructured":"Joshi D, O\u2019Grady J, Dieterich D, Gazzard B, Agarwal K. Increasing burden of liver disease in patients with HIV infection. Lancet. 2011;377(9772):1198\u2013209.","journal-title":"Lancet"},{"issue":"Suppl 1","key":"135_CR39","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1478-3231.2010.02394.x","volume":"31","author":"V Mallet","year":"2011","unstructured":"Mallet V, Vallet-Pichard A, Pol S. The impact of human immunodeficiency virus on viral hepatitis. Liver Int. 2011;31 Suppl 1:135\u20139.","journal-title":"Liver Int"},{"issue":"Suppl 4","key":"135_CR40","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1758-2652-13-S4-P89","volume":"13","author":"AW Colson","year":"2010","unstructured":"Colson AW, Florence E, Augustijn H, Verpooten GA, Lynen L, Gheuens E. Prevalence of chronic renal failure stage 3 or more in HIV-infected patients in Antwerp: an observational study. J Int AIDS Soc. 2010;13 Suppl 4:89.","journal-title":"J Int AIDS Soc"},{"issue":"7","key":"135_CR41","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0929-6646(09)60158-3","volume":"105","author":"TH Lu","year":"2006","unstructured":"Lu TH, Chang HJ, Chen LS, Chu MH, Ou NM, Jen I. Changes in causes of death and associated conditions among persons with HIV\/AIDS after the introduction of highly active antiretroviral therapy in Taiwan. J Formos Med Assoc. 2006;105(7):604\u20139.","journal-title":"J Formos Med Assoc"},{"issue":"3","key":"135_CR42","first-page":"25","volume":"69","author":"F Grippo","year":"2013","unstructured":"Grippo F, Grande E, Pace M. Cause-of-death reporting: how to measure inaccurate completion. GENUS. 2013;69(3):25\u201345.","journal-title":"GENUS"}],"container-title":["Population Health Metrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12963-017-0135-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T02:02:00Z","timestamp":1602122520000},"score":1,"resource":{"primary":{"URL":"http:\/\/pophealthmetrics.biomedcentral.com\/articles\/10.1186\/s12963-017-0135-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,18]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["135"],"URL":"https:\/\/doi.org\/10.1186\/s12963-017-0135-3","relation":{},"ISSN":["1478-7954"],"issn-type":[{"value":"1478-7954","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,18]]},"article-number":"19"}}