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PubMed PMID: 12869955.","DOI":"10.1016\/S1083-8791(03)00151-4"}],"container-title":["Cell Communication and Signaling"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12964-019-0354-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12964-019-0354-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12964-019-0354-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T23:22:14Z","timestamp":1588288934000},"score":1,"resource":{"primary":{"URL":"https:\/\/biosignaling.biomedcentral.com\/articles\/10.1186\/s12964-019-0354-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,2]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["354"],"URL":"https:\/\/doi.org\/10.1186\/s12964-019-0354-2","relation":{},"ISSN":["1478-811X"],"issn-type":[{"value":"1478-811X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,2]]},"assertion":[{"value":"18 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Carlo Follo received his PhD degree in Biotechnologies for Human Health at the University of Piemonte Orientale (Novara, Italy) in 2009. In, 2003, Dr. Follo received his Master\u2019s degree in Industrial Biotechnology at the Universit\u00e0 degli Studi di Milano-Bicocca (Milano, Italy). He performed his PhD studies under the mentorship of Professor Ciro Isidoro. He spent one year as Postdoctoral Investigator at the Albert Einstein College of Medicine (Bronx, NY, USA), and thereafter as Postdoctoral Resercher for three years at Laboratory of Molecular Pathology of Professor Ciro Isidoro (University of Piemonte Orientale, Novara, Italy). From 2014, he is an Associate Specialist at University California San Francisco (UCSF, San Francisco, USA). His research is focused on the contribution of autophagy in mesothelioma.He has co-authored thirty-two articles published in peer-reviewed journals.Chiara Vidoni is a postdoctoral fellow at Universit\u00e0 del Piemonte Orientale in the Laboratory of Molecular Pathology directed by Prof. Ciro Isidoro. In 2017, she received her PhD in Medical Sciences and Biotechnology at Universit\u00e0 del Piemonte Orientale (Novara, Italy), working under the mentorship of Prof. Ciro Isidoro in the Laboratory of Molecular Pathology. She completed her Master\u2019s degree in Medical Biotechnologies at Universit\u00e0 del Piemonte Orientale in 2012. She received her Bachelor\u2019s degree in Biotechnologies at Universit\u00e0 del Piemonte Orientale in 2009. Her current research focused on the role and regulation of autophagy in neurodegenerative diseases, cancer and regenerative medicine.She has co-authored eight articles published in peer-reviewed journals.Federica Morani is currently a post-doctoral researcher at IRCSS Fondazione Stella Maris in Pisa, in Neurogenetics and Molecular Medicine Laboratory directed by Prof. F.M. Santorelli.From March 2013 until September 2014 she obtained a postdoctoral fellow at Laboratory of Molecular Pathology directed by Prof. Ciro Isidoro (Novara, Italy). She received her PhD degree in Clinical and Experimental Medicine at Universit\u00e0 del Piemonte Orientale (Novara, Italy) in 2013. Her work focused on the study of autophagy in several type of cancer (i.e. Glioblastoma, Neuroblastoma, Ovarian Cancer, Thyroid Cancer), particularly in the research of new molecular prognostic markers for Thyroid carcinoma. In 2008, she completed her Master\u2019s degree in Biomolecular Sciences and Technologies cum laude at Universit\u00e0 di Pisa (Pisa, Italy). In 2006, she completed her Bachelor\u2019s degree in Molecular and Biological Sciences cum laude at Universit\u00e0 di Pisa.She has published twenty articles in peer-reviewed journals.Alessandra Ferraresi is a PhD student in Medical Sciences and Biotechnology at Universit\u00e0 del Piemonte Orientale (Novara, Italy), working under the mentorship of Prof. Ciro Isidoro in the Laboratory of Molecular Pathology. She completed her Master\u2019s degree in Pharmaceutical Biotechnologies with honors at Alma Mater Studiorum-Universit\u00e0 di Bologna in 2014. She received her Bachelor\u2019s degree in Biotechnologies at Universit\u00e0 di Parma in 2011. Her current research focused on the role and regulation of autophagy in cancer, particularly in cancer cell migration and resistance to metabolic stress.She has co-authored seven articles published in peer-reviewed journals.Christian Seca is a PhD student in Biomedical and Pharmaceutical Sciences at Laboratory of Cancer Signaling, GIGA-Molecular Biology of Diseases, University of Li\u00e8ge (Belgium). He worked as fellowship recipient at Universit\u00e0 del Piemonte Orientale (Novara, Italy) in the Laboratory of Molecular Pathology under the mentorship of Prof. Ciro Isidoro. His work focused on the regulation of autophagy in cancer and nanobiotechnology and in vitro cellular imaging. He also spent 1 year as research intern in Stephenson Cancer Center, University of Oklahoma Health Sciences Center (USA) in Prof. Danny Dhanasekaran\u2019s Lab.In 2015, he completed his Master\u2019s Degree in Medical Biotechnology with honors at Universit\u00e0 degli Studi di Napoli \u201cFederico II\u201d. In 2012, he completed his Bachelor\u2019s Degree in Biotechnology at Universit\u00e0 degli Studi di Napoli \u201cFederico II\u201d.He has co-authored two articles in peer-reviewed journals.Ciro Isidoro () received his doctoral degree (summa cum laude) in Biological Sciences from the University of Torino (Italy) and his doctoral degree (summa cum laude) in Medicine and Surgery from the University of Piemonte Orientale (Novara, Italy). Currently, he is Professor of Pathology and of Experimental Oncology at the school of Medicine of University of Piemonte Orientale (Novara, Italy). He is also Visiting Professor at the Faculty of Medicine Siriraj Hospital of Mahidol University (Bangkok, Thailand) and at the Department of Cell Biology of the University of Oklahoma Collage of Medicine (Oklahoma City, United States). He is Professeur Honoraire at the Facult\u00e9 de Medecine et de Phamacie de I. Universit\u00e9 de Franche-Comt\u00e9 (Besancon, France). He is member of the scientific board of the \u201cCentre for Integrative Cancer Research\u201d of the Georgia Tech Institute, University of Georgia (Atlanta, US). He is Co-Editor in Chief of the J. of Traditional and Complementary Medicine, and Associate Editor of Autophagy, BMC Cancer, Molecular Carcinogenesis, J. of Ovarian Research, Genes and Cancers, J. of Molecular Signaling, and other journals. His fields of expertise include lysosome biogenesis and function, autophagy regulation in cancer and in neurodegenerative diseases, cell death pathways, mechanisms of action of natural products, epigenetic regulation of autophagy and of cell death.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 information"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"39"}}