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This review suggests that the current knowledge of the role of hTid-1 in disorders like cancers, cardiomyopathies, and neurodegenerative diseases can be correlated with the findings of its protein\u2013protein interactions that can provide a deep insight into the pathways by which hTid-1 affects disease pathogenesis and it can be stated that hTid-1 may serve as an important therapeutic target for these disorders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical Abstract<\/jats:title>\n                \n                \n              <\/jats:sec>","DOI":"10.1186\/s12964-022-00912-5","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T12:06:56Z","timestamp":1658232416000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Putting human Tid-1 in context: an insight into its role in the cell and in different disease states"],"prefix":"10.1186","volume":"20","author":[{"given":"Sagarika","family":"Banerjee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupesh","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anu","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemant R.","family":"Kushwaha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"issue":"1 Pt 2","key":"912_CR1","doi-asserted-by":"publisher","first-page":"R38","DOI":"10.1152\/ajpregu.1995.269.1.R38.PMID7631901","volume":"269","author":"JM Matz","year":"1995","unstructured":"Matz JM, Blake MJ, Tatelman HM, Lavoi KP, Holbrook NJ. 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