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Conversely, poor self-rated health in these domains could precede unfavorable shifts in activity. We evaluated bidirectional associations of accelerometer-estimated time spent in stationary behavior (SB), light intensity physical activity (LPA), and MVPA with self-rated health over 10\u2009years in in the CARDIA longitudinal cohort study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Participants (<jats:italic>n<\/jats:italic>\u2009=\u2009894, age: 45.1\u2009\u00b1\u20093.5; 63% female; 38% black) with valid accelerometry wear and self-rated health at baseline (2005\u20136) and 10-year follow-up (2015\u20136) were included. Accelerometry data were harmonized between exams and measured mean total activity and duration (min\/day) in SB, LPA, and MVPA; duration (min\/day) in long-bout and short-bout SB (\u226530\u2009min vs. &lt;\u200930\u2009min) and MVPA (\u226510\u2009min vs. &lt;\u200910\u2009min) were also quantified. The Short-Form 12 Questionnaire measured both a mental component score (MCS) and physical component score (PCS) of self-rated health (points). Multivariable linear regression associated baseline accelerometry variables with 10-year changes in MCS and PCS. Similar models associated baseline MCS and PCS with 10-year changes in accelerometry measures.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Over 10-years, average (SD) MCS increased 1.05 (9.07) points, PCS decreased by 1.54 (7.30) points, and activity shifted toward greater SB and less mean total activity, LPA, and MVPA (all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Only baseline short-bout MVPA was associated with greater 10-year increases in MCS (+\u20090.92 points, <jats:italic>p<\/jats:italic>\u2009=\u20090.021), while baseline mean total activity, MVPA, and long-bout MVPA were associated with greater 10-year changes in PCS (+\u20090.53 to +\u20091.47 points, all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.005). In the reverse direction, higher baseline MCS and PCS were associated with favorable 10-year changes in mean total activity (+\u20099.75\u2009cpm, <jats:italic>p<\/jats:italic>\u2009=\u20090.040, and\u2009+\u200915.66\u2009cpm, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, respectively) and other accelerometry measures; for example, higher baseline MCS was associated with \u2212\u200913.57\u2009min\/day of long-bout SB (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and higher baseline PCS was associated with +\u20092.83\u2009min\/day of MVPA (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) in fully adjusted models.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The presence of bidirectional associations between SB and activity with self-rated health suggests that individuals with low overall activity levels and poor self-rated health are at high risk for further declines and supports intervention programming that aims to dually increase activity levels and improve self-rated health.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12966-021-01145-4","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T00:02:58Z","timestamp":1622937778000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Bidirectional associations of accelerometer-derived physical activity and stationary behavior with self-reported mental and physical health during midlife"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0732-6148","authenticated-orcid":false,"given":"Bethany","family":"Barone Gibbs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Sternfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara M.","family":"Whitaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer S.","family":"Brach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L.","family":"Hergenroeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"David R.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared P.","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Sidney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelley","family":"Pettee Gabriel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,6]]},"reference":[{"issue":"19","key":"1145_CR1","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1001\/jama.2018.14854","volume":"320","author":"KL Piercy","year":"2018","unstructured":"Piercy KL, Troiano RP, Ballard RM, Carlson SA, Fulton JE, Galuska DA, et al. 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