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Studying the prevalence of no MVPA can provide valuable insights into physical inactivity patterns and inform public health intervention efforts. While some cross-sectional studies have examined this issue, no research has analysed year-to-year trends. Therefore, the aim of this study was to assess trends of no MVPA among adolescents and key subgroups using a nationally representative US sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 2005 to 2021 cycles of the Youth Risk Behavior Surveillance System were used, with 115,926 US adolescents aged 14\u201317 years included (female: unweighted sample size\u2009=\u200958,582, 50.5%; weighted%=49.4%). Participants self-reported their demographic (sex, age, race\/ethnicity, body mass index) and behavioural information (days of \u2265\u200960\u00a0min of MVPA over the past week, and recreational screen time). No MVPA was operationalized as reporting 0 days of \u2265\u200960\u00a0min of MVPA. Trend analysis was performed to assess temporal variations from 2005 to 2021 using a series of binary logistic regression models after controlling for demographic and screen time related variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Declining trends in no MVPA were observed among adolescents from 2005 (weighted: 24.3%) to 2021 (weighted: 15.5%). After stratifying by sex, age, race\/ethnicity, body mass index and recreational screen time, similar downward trends were shown across all adolescent subgroups consistently (\n                      <jats:italic>p<\/jats:italic>\n                      for trend\u2009&lt;\u20090.001). Girls, older adolescents, those who identified as non-White, adolescents with excess weight, and those engaging in more than 2\u00a0h of recreational screen time per day tended to report no MVPA at higher rates (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) compared to their counterparts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>No MVPA has declined among the US adolescents, especially after 2009. Notably, sociodemographic disparities were observed in no MVPA among different population subgroups. PA promotion strategies targeting girls and older adolescents should be prioritized to further reduce the prevalence of no MVPA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12966-025-01862-0","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T10:26:50Z","timestamp":1764844010000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Temporal trends of no moderate to vigorous physical activity in adolescents: a 16-year trend analysis of 115,926 participants"],"prefix":"10.1186","volume":"23","author":[{"given":"Sitong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denver","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Pfledderer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy Y.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Tremblay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"issue":"1","key":"1862_CR1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s12966-020-01037-z","volume":"17","author":"J-P Chaput","year":"2020","unstructured":"Chaput J-P, Willumsen J, Bull F, Chou R, Ekelund U, Firth J, Jago R, Ortega FB, Katzmarzyk PT. 2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5\u201317 years: summary of the evidence. 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