{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:44:59Z","timestamp":1793213099925,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Transl Med"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12967-017-1335-0","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T12:20:21Z","timestamp":1510316421000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["A murine model for developmental dysplasia of the hip: ablation of CX3CR1 affects acetabular morphology and gait"],"prefix":"10.1186","volume":"15","author":[{"given":"George","family":"Feldman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlene","family":"Offemaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hind","family":"Sawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Parvizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa A.","family":"Freeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,11,10]]},"reference":[{"issue":"2","key":"1335_CR1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00016470510030517","volume":"76","author":"S Jacobsen","year":"2005","unstructured":"Jacobsen S, Sonne-Holm S, S\u00f8balle K, Gebuhr P, Lund B. Hip dysplasia and osteoarthritis: a survey of 4,151 subjects from the Osteoarthrosis Substudy of the Copenhagen City Heart Study. Acta Orthop. 2005;76(2):149\u201358.","journal-title":"Acta Orthop"},{"key":"1335_CR2","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1007\/s11999-008-0120-z","volume":"466","author":"M Rubini","year":"2008","unstructured":"Rubini M, Cavallaro A, Calzolari E, Bighetti G, Sollazzo V. Exclusion of COL2A1 and VDR as developmental dysplasia of the hip genes. Clin Orthop Relat Res. 2008;466:878\u201383.","journal-title":"Clin Orthop Relat Res"},{"key":"1335_CR3","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1442-200X.2008.02575.x","volume":"50","author":"C Stein-Zamir","year":"2008","unstructured":"Stein-Zamir C, Volovik I, Rishpon S, Sabi R. Developmental dysplasia of the hip: risk markers, clinical screening and outcome. Pediatr Int. 2008;50:341\u20135.","journal-title":"Pediatr Int"},{"key":"1335_CR4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00003086-199208000-00013","volume":"281","author":"JA Wilkinson","year":"1992","unstructured":"Wilkinson JA. Etiologic factors in congenital displacement of the hip and myelodysplasia. Clin Orthop Relat Res. 1992;281:75\u201383.","journal-title":"Clin Orthop Relat Res"},{"key":"1335_CR5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00003086-196801000-00020","volume":"56","author":"SS Coleman","year":"1968","unstructured":"Coleman SS. Congenital dysplasia of the hip in the Navajo infant. Clin Orthop. 1968;56:179\u201393.","journal-title":"Clin Orthop"},{"issue":"4","key":"1335_CR6","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1302\/0301-620X.52B4.704","volume":"52","author":"R Wynne-Davies","year":"1970","unstructured":"Wynne-Davies R. Acetabular dysplasia and familial joint laxity: two etiological factors in congenital dislocation of the hip. A review of 589 patients and their families. J Bone Joint Surg Br. 1970;52(4):704\u201316.","journal-title":"J Bone Joint Surg Br"},{"key":"1335_CR7","first-page":"397","volume":"48B","author":"J Edelstein","year":"1966","unstructured":"Edelstein J. Congenital dislocation of the hip in the Bantu. J Bone Joint Surg Br. 1966;48B:397.","journal-title":"J Bone Joint Surg Br"},{"issue":"5","key":"1335_CR8","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/BPO.0b013e3181aa586b","volume":"29","author":"DA Stevenson","year":"2009","unstructured":"Stevenson DA, Mineau G, Kerber RA, Viskochil DA, Schaefer C, Roach JW. Familial predisposition to developmental dysplasia of the hip. J Pediatr Orthop. 2009;29(5):463\u20137.","journal-title":"J Pediatr Orthop"},{"key":"1335_CR9","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/00003086-198712000-00007","volume":"225","author":"SL Weinstein","year":"1987","unstructured":"Weinstein SL. Natural history of congenital hip dislocation (CDH) and hip dysplasia. Clin Orthop Relat Res. 1987;225:62\u201376.","journal-title":"Clin Orthop Relat Res"},{"issue":"12","key":"1335_CR10","doi-asserted-by":"publisher","first-page":"2540","DOI":"10.1002\/jbmr.1999","volume":"28","author":"GJ Feldman","year":"2013","unstructured":"Feldman GJ, Parvizi J, Levenstien M, Scott K, Erickson JA, Fortina P, Devoto M, Peters CL. Developmental dysplasia of the hip: linkage mapping and whole exome sequencing identify a shared variant in CX3CR1 in all affected members of a large multigeneration family. J Bone Miner Res. 2013;28(12):2540\u20139. https:\/\/doi.org\/10.1002\/jbmr.1999 .","journal-title":"J Bone Miner Res"},{"key":"1335_CR11","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23294","author":"L Li","year":"2016","unstructured":"Li L, Wang X, Wang BB. et al CX3CR1 polymorphisms associated with increased risk of developmental dysplasia of the hip in human. J Orthop Res. 2016. https:\/\/doi.org\/10.1002\/jor.23294 .","journal-title":"J Orthop Res"},{"issue":"2\u20133","key":"1335_CR12","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.physbeh.2004.04.006","volume":"82","author":"TG Hampton","year":"2004","unstructured":"Hampton TG, Stasko MR, Kale A, Amende I, Costa AC. Gait dynamics in trisomic mice: quantitative neurological traits of Down syndrome. Physiol Behav. 2004;82(2\u20133):381\u20139. https:\/\/doi.org\/10.1016\/j.physbeh.2004.04.006 .","journal-title":"Physiol Behav."},{"key":"1335_CR13","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1182\/blood-2004-09-3507","volume":"106","author":"P Zerbini","year":"2005","unstructured":"Zerbini P, Bonifacio E, Piemonti L, et al. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood. 2005;106:419\u201327.","journal-title":"Blood"},{"key":"1335_CR14","unstructured":"http:\/\/orthoinfo.aaos.org\/topic.cfm?topic=a00347 ."},{"issue":"4","key":"1335_CR15","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2519\/jospt.2014.4634","volume":"44","author":"M Constantinou","year":"2014","unstructured":"Constantinou M, Barrett R, Brown M, Mills P. Spatial-temporal gait characteristics in individuals with hip osteoarthritis: a systematic literature review and meta-analysis. J Ortho Sports Phys Ther. 2014;44(4):291.","journal-title":"J Ortho Sports Phys Ther"},{"key":"1335_CR16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.gaitpost.2009.10.002","volume":"31","author":"JS Brach","year":"2010","unstructured":"Brach JS, Perera S, Verghese J, et al. Meaningful change in measures of gait variability in older adults. Gait Posture. 2010;31:175\u20139.","journal-title":"Gait Posture"},{"issue":"7","key":"1335_CR17","first-page":"1832","volume":"66","author":"B Poulet","year":"2014","unstructured":"Poulet B, de Sousa R, Pitsillides AA, et al. Modifications of gait as predictors of natural osteoarthritis progression in STR\/Ort mice arthritis. Rheumatology. 2014;66(7):1832\u201342.","journal-title":"Rheumatology"},{"key":"1335_CR18","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1471-2474-14-14","volume":"14","author":"SS Parvathy","year":"2013","unstructured":"Parvathy SS, Masocha W. Gait analysis of C57BL\/6 mice with complete Freund\u2019s adjuvant-induced arthritis using the CatWalk system. BMC Musculoskelet Disord. 2013;14:14. https:\/\/doi.org\/10.1186\/1471-2474-14-14 .","journal-title":"BMC Musculoskelet Disord"},{"issue":"11","key":"1335_CR19","doi-asserted-by":"publisher","first-page":"e112889","DOI":"10.1371\/journal.pone.0112889","volume":"9","author":"KKE Gadalla","year":"2014","unstructured":"Gadalla KKE, Ross PD, Riddell JS, Bailey MES, Cobb SR. Gait analysis in a Mecp2 knockout mouse model of rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE. 2014;9(11):e112889. https:\/\/doi.org\/10.1371\/journal.pone.0112889 .","journal-title":"PLoS ONE"},{"issue":"Pt 4","key":"1335_CR20","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1242\/jcs.113910","volume":"126","author":"A Hoshino","year":"2013","unstructured":"Hoshino A, Ueha S, Hanada S, Imai T, Ito M, Yamamoto K, Matsushima K, Yamaguchi A, Iimura T. Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts. J Cell Sci. 2013;126(Pt 4):1032\u201345. https:\/\/doi.org\/10.1242\/jcs.113910 (Epub 2012 Dec 21).","journal-title":"J Cell Sci"}],"container-title":["Journal of Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12967-017-1335-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T00:31:29Z","timestamp":1659832289000},"score":1,"resource":{"primary":{"URL":"https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/s12967-017-1335-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,10]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1335"],"URL":"https:\/\/doi.org\/10.1186\/s12967-017-1335-0","relation":{},"ISSN":["1479-5876"],"issn-type":[{"value":"1479-5876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,10]]},"article-number":"233"}}