{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T04:22:00Z","timestamp":1794111720323,"version":"4.8.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T00:00:00Z","timestamp":1551225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772778"],"award-info":[{"award-number":["81772778"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shandong Province Key Research & Development Program","award":["2017GSF18175"],"award-info":[{"award-number":["2017GSF18175"]}]},{"name":"Fundamental Research Funds of Qilu Hospital of Shangdong University","award":["2082015QLMS44"],"award-info":[{"award-number":["2082015QLMS44"]}],"id":[{"id":"https:\/\/ror.org\/056ef9489","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Transl Med"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12967-019-1814-6","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T06:06:06Z","timestamp":1551247566000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Comprehensive bioinformatics analysis of acquired progesterone resistance in endometrial cancer cell line"],"prefix":"10.1186","volume":"17","author":[{"given":"Wenzhi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunping","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deshui","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9634-4152","authenticated-orcid":false,"given":"Jie","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,2,27]]},"reference":[{"key":"1814_CR1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3322\/caac.21338","volume":"66","author":"W Chen","year":"2016","unstructured":"Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115\u201332. \n                    https:\/\/doi.org\/10.3322\/caac.21338\n                    \n                  .","journal-title":"CA Cancer J Clin"},{"key":"1814_CR2","doi-asserted-by":"publisher","first-page":"S101","DOI":"10.1016\/j.ygyno.2008.07.056","volume":"111","author":"L Chiva","year":"2008","unstructured":"Chiva L, Lapuente F, Gonz\u00e1lez-Cortijo L, Carballo N, Garc\u00eda JF, Rojo A, Gonzalez-Mart\u00edn A. Sparing fertility in young patients with endometrial cancer. Gynecol Oncol. 2008;111:S101\u20134. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2008.07.056\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR3","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.ygyno.2017.07.002","volume":"147","author":"J-L Ethier","year":"2017","unstructured":"Ethier J-L, Desautels DN, Amir E, MacKay H. Is hormonal therapy effective in advanced endometrial cancer? A systematic review and meta-analysis. Gynecol Oncol. 2017;147:158\u201366. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2017.07.002\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR4","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.ygyno.2004.06.045","volume":"95","author":"PT Ramirez","year":"2004","unstructured":"Ramirez PT, Frumovitz M, Bodurka DC, Sun CC, Levenback C. Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review. Gynecol Oncol. 2004;95:133\u20138. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2004.06.045\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR5","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/S0029-7844(97)00297-4","volume":"90","author":"TC Randall","year":"1997","unstructured":"Randall TC, Kurman RJ. Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40. Obstet Gynecol. 1997;90:434\u201340.","journal-title":"Obstet Gynecol"},{"key":"1814_CR6","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1097\/PAS.0b013e31802d68ce","volume":"31","author":"DT Wheeler","year":"2007","unstructured":"Wheeler DT, Bristow RE, Kurman RJ. Histologic alterations in endometrial hyperplasia and well-differentiated carcinoma treated with progestins. Am J Surg Pathol. 2007;31:988\u201398. \n                    https:\/\/doi.org\/10.1097\/PAS.0b013e31802d68ce\n                    \n                  .","journal-title":"Am J Surg Pathol"},{"key":"1814_CR7","doi-asserted-by":"publisher","first-page":"2798","DOI":"10.1200\/JCO.2006.08.8344","volume":"25","author":"K Ushijima","year":"2007","unstructured":"Ushijima K, Yahata H, Yoshikawa H, Konishi I, Yasugi T, Saito T, et al. Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women. JCO. 2007;25:2798\u2013803. \n                    https:\/\/doi.org\/10.1200\/JCO.2006.08.8344\n                    \n                  .","journal-title":"JCO."},{"key":"1814_CR8","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/0002-9378(89)90103-8","volume":"160","author":"A Ferenczy","year":"1989","unstructured":"Ferenczy A, Gelfand M. The biologic significance of cytologic atypia in progestogen-treated endometrial hyperplasia. Am J Obstet Gynecol. 1989;160:126\u201331. \n                    https:\/\/doi.org\/10.1016\/0002-9378(89)90103-8\n                    \n                  .","journal-title":"Am J Obstet Gynecol"},{"key":"1814_CR9","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1055\/s-0029-1242998","volume":"28","author":"J Kim","year":"2010","unstructured":"Kim J, Chapman-Davis E. Role of progesterone in endometrial cancer. Semin Reprod Med. 2010;28:81\u201390. \n                    https:\/\/doi.org\/10.1055\/s-0029-1242998\n                    \n                  .","journal-title":"Semin Reprod Med."},{"key":"1814_CR10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.3892\/ol.2012.975","volume":"5","author":"S Zhao","year":"2013","unstructured":"Zhao S, Li G, Yang L, Li L, Li H. Response-specific progestin resistance in a newly characterized Ishikawa human endometrial cancer subcell line resulting from long-term exposure to medroxyprogesterone acetate. Oncol Lett. 2013;5:139\u201344. \n                    https:\/\/doi.org\/10.3892\/ol.2012.975\n                    \n                  .","journal-title":"Oncol Lett."},{"key":"1814_CR11","doi-asserted-by":"publisher","first-page":"3603","DOI":"10.1002\/cncr.25220","volume":"116","author":"Z Ai","year":"2010","unstructured":"Ai Z, Wang J, Wang Y, Lu L, Tong J, Teng Y. Overexpressed epidermal growth factor receptor (EGFR)-induced progestin insensitivity in human endometrial carcinoma cells by the EGFR\/mitogen-activated protein kinase signaling pathway. Cancer. 2010;116:3603\u201313. \n                    https:\/\/doi.org\/10.1002\/cncr.25220\n                    \n                  .","journal-title":"Cancer"},{"key":"1814_CR12","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.ygyno.2006.12.014","volume":"105","author":"S Zhao","year":"2007","unstructured":"Zhao S, Chen X, Lu X, Yu Y, Feng Y. Epidermal growth factor receptor signaling enhanced by long-term medroxyprogesterone acetate treatment in endometrial carcinoma. Gynecol Oncol. 2007;105:45\u201354. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2006.12.014\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR13","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1111\/j.1447-0756.2012.01881.x","volume":"38","author":"Y Xu","year":"2012","unstructured":"Xu Y, Tong J, Ai Z, Wang J, Teng Y. Epidermal growth factor receptor signaling pathway involved in progestin-resistance of human endometrial carcinoma: in a mouse model. J Obstet Gynaecol Res. 2012;38:1358\u201366. \n                    https:\/\/doi.org\/10.1111\/j.1447-0756.2012.01881.x\n                    \n                  .","journal-title":"J Obstet Gynaecol Res."},{"key":"1814_CR14","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1111\/j.1349-7006.2010.01829.x","volume":"102","author":"C Gu","year":"2011","unstructured":"Gu C, Zhang Z, Yu Y, Liu Y, Zhao F, Yin L, et al. Inhibiting the PI3K\/Akt pathway reversed progestin resistance in endometrial cancer. Cancer Sci. 2011;102:557\u201364. \n                    https:\/\/doi.org\/10.1111\/j.1349-7006.2010.01829.x\n                    \n                  .","journal-title":"Cancer Sci"},{"key":"1814_CR15","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.2147\/OTT.S95267","volume":"10","author":"H Liu","year":"2017","unstructured":"Liu H, Zhang L, Zhang X, Cui Z. PI3K\/AKT\/mTOR pathway promotes progestin resistance in endometrial cancer cells by inhibition of autophagy. Onco Targets Ther. 2017;10:2865\u201371. \n                    https:\/\/doi.org\/10.2147\/OTT.S95267\n                    \n                  .","journal-title":"Onco Targets Ther."},{"key":"1814_CR16","first-page":"1483","volume":"9","author":"R Fan","year":"2017","unstructured":"Fan R, Wang Y, Wang Y, Wei L, Zheng W. Mechanism of progestin resistance in endometrial precancer\/cancer through Nrf2-survivin pathway. Am J Transl Res. 2017;9:1483\u201391.","journal-title":"Am J Transl Res."},{"key":"1814_CR17","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-018-4893-3","author":"Y Wang","year":"2018","unstructured":"Wang Y, Zhang L, Che X, Li W, Liu Z, Jiang J. Roles of SIRT1\/FoxO1\/SREBP-1 in the development of progestin resistance in endometrial cancer. Arch Gynecol Obstet. 2018. \n                    https:\/\/doi.org\/10.1007\/s00404-018-4893-3\n                    \n                  .","journal-title":"Arch Gynecol Obstet."},{"key":"1814_CR18","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1007\/978-3-319-53889-1_25","volume":"978","author":"VE Angarica","year":"2017","unstructured":"Angarica VE, Del Sol A. Bioinformatics tools for genome-wide epigenetic research. Adv Exp Med Biol. 2017;978:489\u2013512. \n                    https:\/\/doi.org\/10.1007\/978-3-319-53889-1_25\n                    \n                  .","journal-title":"Adv Exp Med Biol"},{"key":"1814_CR19","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1186\/1471-2105-12-213","volume":"12","author":"RS Day","year":"2011","unstructured":"Day RS, McDade KK, Chandran UR, Lisovich A, Conrads TP, Hood BL, et al. Identifier mapping performance for integrating transcriptomics and proteomics experimental results. BMC Bioinform. 2011;12:213. \n                    https:\/\/doi.org\/10.1186\/1471-2105-12-213\n                    \n                  .","journal-title":"BMC Bioinform"},{"key":"1814_CR20","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2105-4-2","volume":"4","author":"GD Bader","year":"2003","unstructured":"Bader GD, Hogue CWV. An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinform. 2003;4:2.","journal-title":"BMC Bioinform"},{"key":"1814_CR21","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0090-8258(88)90270-3","volume":"31","author":"JT Chambers","year":"1988","unstructured":"Chambers JT, MacLusky N, Eisenfield A, Kohorn EI, Lawrence R, Schwartz PE. Estrogen and progestin receptor levels as prognosticators for survival in endometrial cancer. Gynecol Oncol. 1988;31:65\u201381.","journal-title":"Gynecol Oncol"},{"key":"1814_CR22","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1038\/modpathol.2009.25","volume":"22","author":"X Chen","year":"2009","unstructured":"Chen X, Zhang Z, Feng Y, Fadare O, Wang J, Ai Z, et al. Aberrant survivin expression in endometrial hyperplasia: another mechanism of progestin resistance. Mod Pathol. 2009;22:699\u2013708. \n                    https:\/\/doi.org\/10.1038\/modpathol.2009.25\n                    \n                  .","journal-title":"Mod Pathol"},{"key":"1814_CR23","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/s0090-8258(02)00008-2","volume":"88","author":"SA Wang","year":"2003","unstructured":"Wang SA, Pudney J, Song J, Mor G, Schwartz PE, Zheng W. Mechanisms involved in the evolution of progestin resistance in human endometrial hyperplasia\u2014precursor of endometrial cancer. Gynecol Oncol. 2003;88:108\u201317. \n                    https:\/\/doi.org\/10.1016\/s0090-8258(02)00008-2\n                    \n                  .","journal-title":"Gynecol Oncol."},{"key":"1814_CR24","doi-asserted-by":"publisher","first-page":"10363","DOI":"10.18632\/oncotarget.7004","volume":"7","author":"Y Wang","year":"2016","unstructured":"Wang Y, Wang Y, Zhang Z, Park J-Y, Guo D, Liao H, et al. Mechanism of progestin resistance in endometrial precancer\/cancer through Nrf2-AKR1C1 pathway. Oncotarget. 2016;7:10363\u201372. \n                    https:\/\/doi.org\/10.18632\/oncotarget.7004\n                    \n                  .","journal-title":"Oncotarget."},{"key":"1814_CR25","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/j.ygyno.2014.11.008","volume":"136","author":"H Zhang","year":"2015","unstructured":"Zhang H, Yan L, Bai Y, Li C, Guo Q, Wang C, et al. Dual-specificity phosphatase 6 predicts the sensitivity of progestin therapy for atypical endometrial hyperplasia. Gynecol Oncol. 2015;136:549\u201353. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2014.11.008\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR26","doi-asserted-by":"publisher","first-page":"41404","DOI":"10.1038\/srep41404","volume":"7","author":"M Dai","year":"2017","unstructured":"Dai M, Zhu X-L, Liu F, Xu Q-Y, Ge Q-L, Jiang S-H, et al. Cholesterol synthetase DHCR24 induced by insulin aggravates cancer invasion and progesterone resistance in endometrial carcinoma. Sci Rep. 2017;7:41404. \n                    https:\/\/doi.org\/10.1038\/srep41404\n                    \n                  .","journal-title":"Sci Rep."},{"key":"1814_CR27","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1210\/me.2011-1355","volume":"26","author":"CA Rubel","year":"2012","unstructured":"Rubel CA, Lanz RB, Kommagani R, Franco HL, Lydon JP, DeMayo FJ. Research resource: genome-wide profiling of progesterone receptor binding in the mouse uterus. Mol Endocrinol. 2012;26:1428\u201342. \n                    https:\/\/doi.org\/10.1210\/me.2011-1355\n                    \n                  .","journal-title":"Mol Endocrinol"},{"key":"1814_CR28","doi-asserted-by":"publisher","first-page":"84996","DOI":"10.18632\/oncotarget.18662","volume":"8","author":"H Wu","year":"2017","unstructured":"Wu H, Wang H, Guan S, Zhang J, Chen Q, Wang X, et al. Cell-specific regulation of proliferation by Ano1\/TMEM16A in breast cancer with different ER, PR, and HER2 status. Oncotarget. 2017;8:84996\u20135013. \n                    https:\/\/doi.org\/10.18632\/oncotarget.18662\n                    \n                  .","journal-title":"Oncotarget."},{"key":"1814_CR29","doi-asserted-by":"publisher","first-page":"e0126128","DOI":"10.1371\/journal.pone.0126128","volume":"10","author":"H Wu","year":"2015","unstructured":"Wu H, Guan S, Sun M, Yu Z, Zhao L, He M, et al. Ano1\/TMEM16A overexpression is associated with good prognosis in PR-positive or HER2-negative breast cancer patients following tamoxifen treatment. PLoS ONE. 2015;10:e0126128. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0126128\n                    \n                  .","journal-title":"PLoS ONE"},{"key":"1814_CR30","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1210\/me.2015-1079","volume":"29","author":"AM Blessing","year":"2015","unstructured":"Blessing AM, Ganesan S, Rajapakshe K, Ying Sung Y, Reddy Bollu L, Shi Y, et al. Identification of a novel coregulator, SH3YL1, that interacts with the androgen receptor N-terminus. Mol Endocrinol. 2015;29:1426\u201339. \n                    https:\/\/doi.org\/10.1210\/me.2015-1079\n                    \n                  .","journal-title":"Mol Endocrinol"},{"key":"1814_CR31","doi-asserted-by":"publisher","first-page":"93502","DOI":"10.18632\/oncotarget.19548","volume":"8","author":"J Wu","year":"2017","unstructured":"Wu J, Bao L, Zhang Z, Yi X. Nrf2 induces cisplatin resistance via suppressing the iron export related gene SLC40A1 in ovarian cancer cells. Oncotarget. 2017;8:93502\u201315. \n                    https:\/\/doi.org\/10.18632\/oncotarget.19548\n                    \n                  .","journal-title":"Oncotarget."},{"key":"1814_CR32","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1111\/j.1600-0897.2004.00248.x","volume":"53","author":"CR Wira","year":"2005","unstructured":"Wira CR, Grant-Tschudy KS, Crane-Godreau MA. Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection. Am J Reprod Immunol. 2005;53:65\u201376. \n                    https:\/\/doi.org\/10.1111\/j.1600-0897.2004.00248.x\n                    \n                  .","journal-title":"Am J Reprod Immunol"},{"key":"1814_CR33","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1126\/science.286.5439.525","volume":"286","author":"D Yang","year":"1999","unstructured":"Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, et al. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science. 1999;286:525\u20138.","journal-title":"Science"},{"key":"1814_CR34","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.ygyno.2006.01.045","volume":"103","author":"BF Barrier","year":"2006","unstructured":"Barrier BF, Kendall BS, Sharpe-Timms KL, Kost ER. Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma. Gynecol Oncol. 2006;103:25\u201330. \n                    https:\/\/doi.org\/10.1016\/j.ygyno.2006.01.045\n                    \n                  .","journal-title":"Gynecol Oncol"},{"key":"1814_CR35","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1210\/endo.131.3.1505448","volume":"131","author":"AL Jacobs","year":"1992","unstructured":"Jacobs AL, Sehgal PB, Julian J, Carson DD. Secretion and hormonal regulation of interleukin-6 production by mouse uterine stromal and polarized epithelial cells cultured in vitro. Endocrinology. 1992;131:1037\u201346. \n                    https:\/\/doi.org\/10.1210\/endo.131.3.1505448\n                    \n                  .","journal-title":"Endocrinology"},{"key":"1814_CR36","doi-asserted-by":"publisher","first-page":"2266","DOI":"10.1101\/gad.9.18.2266","volume":"9","author":"JP Lydon","year":"1995","unstructured":"Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA, et al. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 1995;9:2266\u201378.","journal-title":"Genes Dev"},{"key":"1814_CR37","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1677\/JOE-10-0072","volume":"206","author":"AE Wallace","year":"2010","unstructured":"Wallace AE, Gibson DA, Saunders PTK, Jabbour HN. Inflammatory events in endometrial adenocarcinoma. J Endocrinol. 2010;206:141\u201357. \n                    https:\/\/doi.org\/10.1677\/JOE-10-0072\n                    \n                  .","journal-title":"J Endocrinol"},{"key":"1814_CR38","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/S0005-2736(99)00161-3","volume":"1461","author":"I Klein","year":"1999","unstructured":"Klein I, Sarkadi B, V\u00e1radi A. An inventory of the human ABC proteins. Biochim Biophys Acta. 1999;1461:237\u201362.","journal-title":"Biochim Biophys Acta"},{"key":"1814_CR39","doi-asserted-by":"publisher","first-page":"5726","DOI":"10.1158\/0008-5472.CAN-09-0390","volume":"69","author":"AE Wallace","year":"2009","unstructured":"Wallace AE, Sales KJ, Catalano RD, Anderson RA, Williams ARW, Wilson MR, et al. Prostaglandin F2alpha-F-prostanoid receptor signaling promotes neutrophil chemotaxis via chemokine (C-X-C motif) ligand 1 in endometrial adenocarcinoma. Cancer Res. 2009;69:5726\u201333. \n                    https:\/\/doi.org\/10.1158\/0008-5472.CAN-09-0390\n                    \n                  .","journal-title":"Cancer Res"},{"key":"1814_CR40","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1046\/j.1525-1438.2001.011001054.x","volume":"11","author":"KK Berry","year":"2001","unstructured":"Berry KK, Varney ML, Dave BJ, Bucana CD, Fidler IJ, Singh RK. Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines. Int J Gynecol Cancer. 2001;11:54\u201360.","journal-title":"Int J Gynecol Cancer."},{"key":"1814_CR41","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1189\/jlb.3A0914-430RR","volume":"99","author":"V Pelekanou","year":"2016","unstructured":"Pelekanou V, Kampa M, Kiagiadaki F, Deli A, Theodoropoulos P, Agrogiannis G, et al. Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ER\u03b136 and GPR30\/GPER1. J Leukoc Biol. 2016;99:333\u201347. \n                    https:\/\/doi.org\/10.1189\/jlb.3A0914-430RR\n                    \n                  .","journal-title":"J Leukoc Biol"},{"key":"1814_CR42","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1016\/j.chembiol.2011.05.009","volume":"18","author":"DK Nomura","year":"2011","unstructured":"Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, et al. monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer. Chem Biol. 2011;18:846\u201356. \n                    https:\/\/doi.org\/10.1016\/j.chembiol.2011.05.009\n                    \n                  .","journal-title":"Chem Biol"},{"key":"1814_CR43","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/nrc3483","volume":"13","author":"A Carracedo","year":"2013","unstructured":"Carracedo A, Cantley LC, Pandolfi PP. Cancer metabolism: fatty acid oxidation in the limelight. Nat Rev Cancer. 2013;13:227\u201332. \n                    https:\/\/doi.org\/10.1038\/nrc3483\n                    \n                  .","journal-title":"Nat Rev Cancer"},{"key":"1814_CR44","doi-asserted-by":"publisher","first-page":"2348","DOI":"10.4161\/cc.20811","volume":"11","author":"W Li","year":"2012","unstructured":"Li W, Tai Y, Zhou J, Gu W, Bai Z, Zhou T, et al. Repression of endometrial tumor growth by targeting SREBP1 and lipogenesis. Cell Cycle. 2012;11:2348\u201358. \n                    https:\/\/doi.org\/10.4161\/cc.20811\n                    \n                  .","journal-title":"Cell Cycle"},{"key":"1814_CR45","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1097\/IGC.0000000000000004","volume":"23","author":"C Qiu","year":"2013","unstructured":"Qiu C, Dongol S, Lv Q-T, Gao X, Jiang J. Sterol regulatory element-binding protein-1\/fatty acid synthase involvement in proliferation inhibition and apoptosis promotion induced by progesterone in endometrial cancer. Int J Gynecol Cancer. 2013;23:1629\u201334. \n                    https:\/\/doi.org\/10.1097\/IGC.0000000000000004\n                    \n                  .","journal-title":"Int J Gynecol Cancer."}],"container-title":["Journal of Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12967-019-1814-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12967-019-1814-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12967-019-1814-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T19:09:50Z","timestamp":1582744190000},"score":1,"resource":{"primary":{"URL":"https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/s12967-019-1814-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,27]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["1814"],"URL":"https:\/\/doi.org\/10.1186\/s12967-019-1814-6","relation":{},"ISSN":["1479-5876"],"issn-type":[{"value":"1479-5876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,27]]},"assertion":[{"value":"29 August 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"58"}}