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Written informed consents were obtained for all individuals included in the study, which was approved by the Ethical Committees of the Hospital Universitario Ram\u00f3n y Cajal (Madrid) and the University Hospital Germans Trias i Pujol (HUGTiP) in Badalona.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication was obtained from the three affected subjects of family SH19.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"290"}}