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Measurements were taken with an automated tool to avoid human error. All patients were evaluated in the supine position. Patients were then stratified into two groups, VWT\u2009&gt;\u20091\u00a0mm and VWT\u2009&lt;\u20091\u00a0mm. Lung damage was assessed through thoracic High Resolution Computer Tomography and subsequently quantified using the scoring system set out by Chung et al. CEAP-C class was calculated for all patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean value of COVID score in VWT\u2009&gt;\u20091\u00a0mm group was 7.4 (S.D. 4.83), whilst the mean value of the COVID score in the VWT\u2009&lt;\u20091\u00a0mm group was 3.82 (S.D 3.34). These findings were determined to be statistically significant in a two-tie Student-T test. The linear regression test between VWT and Covid score values demonstrated a direct relationship between the two variables.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>These results demonstrate a link between two different aspects of the pathological effects on the vessels during a SARS-COV 2 infection. As such a common <jats:italic>primum movens<\/jats:italic> can be hypothesized in both micro-thrombotic and inflammatory processes relating to COVID 19.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12967-024-04857-w","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T17:34:48Z","timestamp":1705512888000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vein wall thickness and severity of pulmonary involvement due to sars n-cov2 virus 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Informed consent for participation in the study could be given orally if a written consent was unfeasible. However, if patients lack capacity to consent due to disease severity, and an authorized representative was not immediately available, radiological imaging and laboratory tests could be administered by the treating physician on her\/ his own responsibility.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate."}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Authors declare that they have no competing interests which could have influenced the results of this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"70"}}