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This study was approved by Ethics Committee of the Cancer Hospital of China Medical University (ID: KY20230719). Informed consent was obtained from each participant. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). The animal research protocol was approved by the Animal Center of China Medical University, in compliance with institutional guidelines for the care and use of animals.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"284"}}