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Patients were enrolled at AOU Mater Domini in accordance with the guidelines of the Institutional Review Board of AOU Mater Domini \/ University Magna Graecia (Catanzaro, Italy). The study was approved by the Institutional Review Board in the meeting of May 21st, 2014. Tumor specimens were collected from patients who underwent surgical resection for rectal cancer at the General Surgery Unit of the University Hospital Magna Graecia of Catanzaro. Bioptic samples were immediately snap-frozen and stored at\u2009\u2212\u200980\u00a0\u00b0C. Eligibility criteria included no prior exposure to chemotherapy or radiotherapy before surgery. All collected samples were confirmed to be suitable for subsequent molecular analyses.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors approved the manuscript publication in Journal of Translational Medicine.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All other authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"869"}}