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All animal experimental protocols were conducted according to the National Guidelines for Animal Usage in Research (China) and approved by the Experimental Animal Ethics Committee of Tongji Medical College, Huazhong University of Science and Technology (No.2024-3948).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare they have no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1079"}}