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All procedures involving human liver samples were conducted in accordance with the Declaration of Helsinki and were approved by the Ethics Committee of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine. All animal protocols were approved by the Ethics Committee of Laboratory Animal Center Fudan University. All experimental procedures complied with the World Medical Association Declaration of Helsinki on animal research ethics and adhered to EU Directive 2010\/63\/EU standards for pharmacological studies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"442"}}