{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:33:00Z","timestamp":1793323980063,"version":"4.5.0"},"reference-count":324,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":46,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Transl Med"],"DOI":"10.1186\/s12967-026-08104-2","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T16:32:56Z","timestamp":1775838776000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Mitochondrial dysfunction in neonatal brain injury: from molecular mechanisms to therapeutic interventions"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0600-6899","authenticated-orcid":false,"given":"Chengqian","family":"Teng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4076-5013","authenticated-orcid":false,"given":"Jianjie","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8739-6652","authenticated-orcid":false,"given":"Yixiao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8521-8284","authenticated-orcid":false,"given":"Andi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1864-6729","authenticated-orcid":false,"given":"Xiaohui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"issue":"2","key":"8104_CR1","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1038\/s41390-021-01818-7","volume":"91","author":"J Herz","year":"2022","unstructured":"Herz J, Bendix I, Felderhoff-M\u00fcser U. Peripheral immune cells and perinatal brain injury: a double-edged sword? Pediatr Res. 2022;91(2):392\u2013403.","journal-title":"Pediatr Res"},{"key":"8104_CR2","doi-asserted-by":"crossref","unstructured":"Tann CJ, Nakakeeto M, Willey BA, Sewegaba M, Webb EL, Oke I, et al. Perinatal risk factors for neonatal encephalopathy: an unmatched case-control study. Arch Dis Child Fetal Neonatal Ed. 2018;103(3):F250\u2013f256.","DOI":"10.1136\/archdischild-2017-312744"},{"key":"8104_CR3","doi-asserted-by":"crossref","unstructured":"Chakkarapani E, de Vries LS, Ferriero DM, Gunn AJ. Neonatal encephalopathy and hypoxic-ischemic encephalopathy: the state of the art. Pediatr Res. 2025.","DOI":"10.1038\/s41390-025-03986-2"},{"issue":"6","key":"8104_CR4","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","volume":"86","author":"JJ Kurinczuk","year":"2010","unstructured":"Kurinczuk JJ, White-Koning M, Badawi N. Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev. 2010;86(6):329\u201338.","journal-title":"Early Hum Dev"},{"key":"8104_CR5","doi-asserted-by":"publisher","first-page":"142","DOI":"10.3389\/fped.2019.00142","volume":"7","author":"S Aslam","year":"2019","unstructured":"Aslam S, Strickland T, Molloy EJ. Neonatal encephalopathy: need for recognition of multiple etiologies for optimal management. Front. Pediatr. 2019;7:142.","journal-title":"Front. Pediatr"},{"key":"8104_CR6","doi-asserted-by":"crossref","unstructured":"Ehlting A, Zweyer M, Maes E, Schleehuber Y, Doshi H, Sabir H, et al. Impact of hypoxia-ischemia on neurogenesis and structural and functional outcomes in a mild-moderate neonatal hypoxia-ischemia brain injury model. Life. 2022;12(8).","DOI":"10.3390\/life12081164"},{"key":"8104_CR7","doi-asserted-by":"crossref","unstructured":"Jung DH, Pak ME, Lee HJ, Ahn SM, Yun YJ, Shin YI, et al. Electroacupuncture on the Scalp over the motor cortex ameliorates behavioral deficits following neonatal hypoxia-ischemia in rats via the activation of neural stem cells. Life (Basel, Switz). 2020;10(10).","DOI":"10.3390\/life10100240"},{"key":"8104_CR8","volume-title":"Neonatal therapeutic hypothermia. in","author":"M Shah","year":"2025","unstructured":"Shah M, Sakr M, Balasundaram P. Neonatal therapeutic hypothermia. in. StatPearls. edn. Treasure Island (FL): StatPearls Publishing, Copyright \u00a9 2025, StatPearls Publishing LLC.; 2025.","edition":"StatPearls. edn"},{"key":"8104_CR9","doi-asserted-by":"crossref","unstructured":"Kose Cetinkaya A, Sari FN, Keceli AM, Akin MS, Butun Turk S, Ertekin O. Alyamac Dizdar E: brain injury patterns and Short-TermOutcomes in late preterm infants treated with hypothermia for hypoxic ischemic encephalopathy. Children (Basel). 2025;12(8).","DOI":"10.3390\/children12081012"},{"issue":"2","key":"8104_CR10","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s11910-019-0916-0","volume":"19","author":"G Wassink","year":"2019","unstructured":"Wassink G, Davidson JO, Dhillon SK, Zhou K, Bennet L, Thoresen M, et al. Therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy. Curr Neurol Neurosci Rep. 2019;19(2):2.","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"4","key":"8104_CR11","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1177\/1073858415585472","volume":"22","author":"JM Xavier","year":"2016","unstructured":"Xavier JM, Rodrigues CM, Sol\u00e1 S. Mitochondria: major regulators of neural development. The Neuroscientist: Rev J Bringing Neurobiol, Neurol Psychiatry. 2016;22(4):346\u201358.","journal-title":"The Neuroscientist: Rev J Bringing Neurobiol, Neurol Psychiatry"},{"key":"8104_CR12","doi-asserted-by":"crossref","unstructured":"Rossmann MP, Dubois SM, Agarwal S, Zon LI. Mitochondrial function in development and disease. Disease Model Mechanisms. 2021;14(6).","DOI":"10.1242\/dmm.048912"},{"issue":"9\u201310","key":"8104_CR13","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s12272-023-01465-y","volume":"46","author":"SS Prabhu","year":"2023","unstructured":"Prabhu SS, Nair AS, Nirmala SV. Multifaceted roles of mitochondrial dysfunction in diseases: from powerhouses to saboteurs. Arch Pharm Res. 2023;46(9\u201310):723\u201343.","journal-title":"Arch. Pharm. Res"},{"key":"8104_CR14","doi-asserted-by":"crossref","unstructured":"Chandel NS, Mitochondria. Cold Spring harbor perspectives in biology. 2021;13(3).","DOI":"10.1101\/cshperspect.a040543"},{"issue":"4","key":"8104_CR15","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1152\/physrev.00058.2021","volume":"103","author":"JS Harrington","year":"2023","unstructured":"Harrington JS, Ryter SW, Plataki M, Price DR, Choi AMK. Mitochondria in health, disease, and aging. Physiol Rev. 2023;103(4):2349\u2013422.","journal-title":"Physiol Rev"},{"issue":"12","key":"8104_CR16","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1016\/j.neuron.2022.03.015","volume":"110","author":"XT Cheng","year":"2022","unstructured":"Cheng XT, Huang N, Sheng ZH. Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration. Neuron. 2022;110(12):1899\u2013923.","journal-title":"Neuron"},{"key":"8104_CR17","doi-asserted-by":"crossref","unstructured":"Li Y, Zhang H, Yu C, Dong X, Yang F, Wang M, et al. New insights into mitochondria in health and diseases. Int J Mol Sci. 2024;25(18).","DOI":"10.3390\/ijms25189975"},{"key":"8104_CR18","doi-asserted-by":"crossref","unstructured":"Jones A, Thornton C. Mitochondrial dynamics in the neonatal brain - a potential target following injury? Biosci Rep. 2022;42(3).","DOI":"10.1042\/BSR20211696"},{"key":"8104_CR19","doi-asserted-by":"crossref","unstructured":"Curel CJM, Nobeli I, Thornton C. Leflunomide treatment Does not protect neural cells following oxygen-glucose deprivation (OGD) in vitro. Cells. 2024;13(7).","DOI":"10.3390\/cells13070631"},{"issue":"4","key":"8104_CR20","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1089\/ars.2020.8093","volume":"33","author":"M Rodr\u00edguez","year":"2020","unstructured":"Rodr\u00edguez M, Valez V, Cimarra C, Blasina F, Radi R. Hypoxic-ischemic encephalopathy and mitochondrial dysfunction: facts, unknowns, and challenges. Antioxid Redox Signal. 2020;33(4):247\u201362.","journal-title":"Antioxid Redox Signal"},{"key":"8104_CR21","doi-asserted-by":"publisher","first-page":"108698","DOI":"10.1016\/j.abb.2020.108698","volume":"702","author":"J Johnson","year":"2021","unstructured":"Johnson J, Mercado-Ayon E, Mercado-Ayon Y, Dong YN, Halawani S, Ngaba L, et al. Mitochondrial dysfunction in the development and progression of neurodegenerative diseases. Archives Biochem Biophys. 2021;702:108698.","journal-title":"Archives Biochem Biophys"},{"key":"8104_CR22","doi-asserted-by":"crossref","unstructured":"Jones A, Thornton C. Mitochondrial dynamics in the neonatal brain - a potential target following injury? Biosci Rep. 2022;42(3).","DOI":"10.1042\/BSR20211696"},{"key":"8104_CR23","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.semcdb.2019.05.022","volume":"98","author":"M Abate","year":"2020","unstructured":"Abate M, Festa A, Falco M, Lombardi A, Luce A, Grimaldi A, et al. Mitochondria as playmakers of apoptosis, autophagy and senescence. Semin Cell Dev Biol. 2020;98:139\u201353.","journal-title":"Semin Cell Dev Biol"},{"issue":"1","key":"8104_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s43440-025-00819-1","volume":"78","author":"M Fra\u0144czak","year":"2026","unstructured":"Fra\u0144czak M, Garga\u015b J, Sypecka J. Mitochondria as a therapeutic target in neurodegeneration caused by hypoxia and ischemia during the perinatal period. Pharmacol Rep. 2026;78(1):1\u201326.","journal-title":"Pharmacol Rep"},{"issue":"6","key":"8104_CR25","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1515\/jpm-2022-0523","volume":"51","author":"B Strizek","year":"2023","unstructured":"Strizek B. Perinatal brain damage - what the obstetrician needs to know. J Perinat Med. 2023;51(6):752\u201356.","journal-title":"J Perinat Med"},{"issue":"3","key":"8104_CR26","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/j.clp.2015.04.011","volume":"42","author":"ML Tataranno","year":"2015","unstructured":"Tataranno ML, Perrone S, Buonocore G. Plasma biomarkers of oxidative stress in neonatal brain injury. Clin Perinatol. 2015;42(3):529\u201339.","journal-title":"Clin Perinatol"},{"key":"8104_CR27","doi-asserted-by":"crossref","unstructured":"Gale C, Statnikov Y, Jawad S, Uthaya SN, Modi N. Neonatal brain injuries in England: population-based incidence derived from routinely recorded clinical data held in the national neonatal research database. Arch Dis Child Fetal Neonatal Ed. 2018;103(4):F301\u2013f306.","DOI":"10.1136\/archdischild-2017-313707"},{"key":"8104_CR28","doi-asserted-by":"publisher","first-page":"955","DOI":"10.3389\/fphys.2019.00955","volume":"10","author":"HB Stolp","year":"2019","unstructured":"Stolp HB, Fleiss B, Arai Y, Supramaniam V, Vontell R, Birtles S, et al. Interneuron development is disrupted in preterm brains with diffuse white matter injury: observations in mouse and human. Front Physiol. 2019;10:955.","journal-title":"Front. Physiol"},{"issue":"5","key":"8104_CR29","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1017\/S0033291714001998","volume":"45","author":"M Lahti","year":"2015","unstructured":"Lahti M, Eriksson JG, Heinonen K, Kajantie E, Lahti J, Wahlbeck K, et al. Late preterm birth, post-term birth, and abnormal fetal growth as risk factors for severe mental disorders from early to late adulthood. Psychol Med. 2015;45(5):985\u201399.","journal-title":"Psychol Med"},{"key":"8104_CR30","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.pediatrneurol.2017.11.006","volume":"80","author":"AS Smilga","year":"2018","unstructured":"Smilga AS, Garfinkle J, Ng P, Andersen J, Buckley D, Fehlings D, et al. Neonatal infection in Children with cerebral palsy: a registry-based cohort study. Pediatr Neurol. 2018;80:77\u201383.","journal-title":"Pediatr Neurol"},{"issue":"1","key":"8104_CR31","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1186\/s12887-024-04977-8","volume":"24","author":"WJ Ong","year":"2024","unstructured":"Ong WJ, Seng JJB, Yap B, He G, Moochhala NA, Ng CL, et al. Impact of neonatal sepsis on neurocognitive outcomes: a systematic review and meta-analysis. BMC Pediatr. 2024;24(1):505.","journal-title":"BMC Pediatr"},{"key":"8104_CR32","doi-asserted-by":"crossref","unstructured":"Ranjan AK, Gulati A. Advances in therapies to Treat neonatal hypoxic-ischemic encephalopathy. J Clin Med. 2023;12(20).","DOI":"10.3390\/jcm12206653"},{"key":"8104_CR33","doi-asserted-by":"crossref","unstructured":"Ehlting A, Zweyer M, Maes E, Schleehuber Y, Doshi H, Sabir H, et al. Impact of hypoxia-ischemia on neurogenesis and structural and functional outcomes in a mild-moderate neonatal hypoxia-ischemia brain injury model. Life (Basel, Switz). 2022;12(8).","DOI":"10.3390\/life12081164"},{"key":"8104_CR34","doi-asserted-by":"crossref","unstructured":"Acun C, Karnati S, Padiyar S, Puthuraya S, Aly H, Mohamed M. Trends of neonatal hypoxic-ischemic encephalopathy prevalence and associated risk factors in the United States & comma; 2010 to 2018. Am J Obstet Gynecol. 2022;227(5):.e751.751\u2013751.710.","DOI":"10.1016\/j.ajog.2022.06.002"},{"issue":"5","key":"8104_CR35","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.55730\/1300-0144.5481","volume":"52","author":"E Kele\u015f","year":"2022","unstructured":"Kele\u015f E, Kazan HH, Aral A, Bolay H. Microglial iron trafficking: new player in brain injury. Turk J Med Sci. 2022;52(5):1415\u201324.","journal-title":"Turk J Med Sci"},{"issue":"1","key":"8104_CR36","first-page":"30","volume":"23","author":"F Dom\u00ednguez-Dieppa","year":"2021","unstructured":"Dom\u00ednguez-Dieppa F, Cardetti M, Rodr\u00edguez S, Garc\u00eda-Alix A, Sola A. Hypoxic ischemic encephalopathy in units reporting to the Ibero-American Society of Neonatology network: prevalence and mortality. MEDICC Rev. 2021;23(1):30\u201334.","journal-title":"MEDICC Rev"},{"key":"8104_CR37","doi-asserted-by":"crossref","unstructured":"Frajewicki A, La\u0161t\u016fvka Z, Borb\u00e9lyov\u00e1 V, Khan S, Jandov\u00e1 K, Jani\u0161ov\u00e1 K, et al. Perinatal hypoxic-ischemic damage: review of the current treatment possibilities. Physiol Res. 2020;69(Suppl 3):S379\u2013s401.","DOI":"10.33549\/physiolres.934595"},{"key":"8104_CR38","doi-asserted-by":"crossref","unstructured":"Ma\u00efza A, Hamoudi R, Mabondzo A. Targeting the multiple complex processes of hypoxia-ischemia to achieve neuroprotection. Int J Mol Sci. 2024;25(10).","DOI":"10.3390\/ijms25105449"},{"issue":"1\u20132","key":"8104_CR39","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1177\/08830738221147805","volume":"38","author":"KE Woodward","year":"2023","unstructured":"Woodward KE, Murthy P, Mineyko A, Mohammad K, Esser MJ. Identifying genetic susceptibility in neonates with hypoxic-ischemic encephalopathy: a retrospective case series. J Child Neurol. 2023;38(1\u20132):16\u201324.","journal-title":"J Child Neurol"},{"key":"8104_CR40","doi-asserted-by":"publisher","first-page":"113457","DOI":"10.1016\/j.expneurol.2020.113457","volume":"334","author":"N Hamdy","year":"2020","unstructured":"Hamdy N, Eide S, Sun HS, Feng ZP. Animal models for neonatal brain injury induced by hypoxic ischemic conditions in rodents. Exp Neurol. 2020;334:113457.","journal-title":"Exp Neurol"},{"key":"8104_CR41","doi-asserted-by":"publisher","first-page":"709301","DOI":"10.3389\/fnsyn.2021.709301","volume":"13","author":"K Tetorou","year":"2021","unstructured":"Tetorou K, Sisa C, Iqbal A, Dhillon K, Hristova M. Current therapies for neonatal hypoxic-ischaemic and infection-Sensitised hypoxic-ischaemic brain damage. Front Synaptic Neurosci. 2021;13:709301.","journal-title":"Front Synaptic Neurosci"},{"issue":"2","key":"8104_CR42","doi-asserted-by":"publisher","first-page":"205","DOI":"10.4103\/1673-5374.290875","volume":"16","author":"J Rodriguez","year":"2021","unstructured":"Rodriguez J, Li T, Xu Y, Sun Y, Zhu C. Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury. Neural Regen Res. 2021;16(2):205\u201313.","journal-title":"Neural Regen Res"},{"key":"8104_CR43","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/j.jconrel.2020.12.056","volume":"330","author":"R Narayanamurthy","year":"2021","unstructured":"Narayanamurthy R, Yang JJ, Yager JY, Unsworth LD. Drug delivery platforms for neonatal brain injury. J Control Release. 2021;330:765\u201387.","journal-title":"J Control Release"},{"issue":"2","key":"8104_CR44","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1007\/s12035-024-04398-9","volume":"62","author":"M Yang","year":"2025","unstructured":"Yang M, Wang K, Liu B, Shen Y, Liu G. Hypoxic-ischemic encephalopathy: pathogenesis and promising therapies. Mol Neurobiol. 2025;62(2):2105\u201322.","journal-title":"Mol Neurobiol"},{"issue":"10","key":"8104_CR45","doi-asserted-by":"publisher","first-page":"2229","DOI":"10.4103\/1673-5374.369117","volume":"18","author":"TL Zhang","year":"2023","unstructured":"Zhang TL, Zhang ZW, Lin W, Lin XR, Lin KX, Fang MC, et al. Reperfusion after hypoxia-ischemia exacerbates brain injury with compensatory activation of the anti- ferroptosis system: based on a novel rat model. Neural Regen Res. 2023;18(10):2229\u201336.","journal-title":"Neural Regen Res"},{"key":"8104_CR46","doi-asserted-by":"publisher","first-page":"1479765","DOI":"10.3389\/fphar.2024.1479765","volume":"15","author":"J Wang","year":"2024","unstructured":"Wang J, Su P, Wan C, Xu Y, Huang J, Niu J, et al. Role of salvianolic acid B in the treatment of acute ischemic stroke: a systematic review and meta-analysis of animal models. Front Pharmacol. 2024;15:1479765.","journal-title":"Front Pharmacol"},{"issue":"9966","key":"8104_CR47","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/S0140-6736(14)61698-6","volume":"385","author":"L Liu","year":"2015","unstructured":"Liu L, Oza S, Hogan D, Perin J, Rudan I, Lawn JE, et al. Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet (Lond, Engl). 2015;385(9966):430\u201340.","journal-title":"Lancet (Lond, Engl)"},{"issue":"9832","key":"8104_CR48","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1016\/S0140-6736(12)60560-1","volume":"379","author":"L Liu","year":"2012","unstructured":"Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet (Lond, Engl). 2012;379(9832):2151\u201361.","journal-title":"Lancet (Lond, Engl)"},{"key":"8104_CR49","doi-asserted-by":"crossref","unstructured":"Ophelders D, Gussenhoven R, Klein L, Jellema RK, Westerlaken RJJ, H\u00fctten MC, et al. Wolfs T: preterm brain injury, antenatal triggers, and therapeutics: timing is key. Cells. 2020;9(8).","DOI":"10.3390\/cells9081871"},{"key":"8104_CR50","doi-asserted-by":"publisher","first-page":"100772","DOI":"10.1016\/j.spen.2019.08.008","volume":"32","author":"P Parikh","year":"2019","unstructured":"Parikh P, Juul SE. Neuroprotection strategies in preterm encephalopathy. Semin Pediatr Neurol. 2019;32:100772.","journal-title":"Semin Pediatr Neurol"},{"key":"8104_CR51","doi-asserted-by":"crossref","unstructured":"Rees P, Callan C, Chadda KR, Vaal M, Diviney J, Sabti S, et al. Preterm brain injury and neurodevelopmental outcomes: a meta-analysis. Pediatrics. 2022;150(6).","DOI":"10.1542\/peds.2022-057442"},{"issue":"1","key":"8104_CR52","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s11689-018-9253-x","volume":"10","author":"CE Rogers","year":"2018","unstructured":"Rogers CE, Lean RE, Wheelock MD, Smyser CD. Aberrant structural and functional connectivity and neurodevelopmental impairment in preterm children. J Neurodev Disord. 2018;10(1):38.","journal-title":"J Neurodev Disord"},{"key":"8104_CR53","doi-asserted-by":"crossref","unstructured":"Park B, Khanam R, Vinayachandran V, Baqui AH, London SJ, Biswal S. Epigenetic biomarkers and preterm birth. Environ Epigenet. 2020;6(1):dvaa005.","DOI":"10.1093\/eep\/dvaa005"},{"issue":"6","key":"8104_CR54","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1038\/s41390-023-02717-9","volume":"94","author":"K Terada","year":"2023","unstructured":"Terada K, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Oka S, Ukai R, et al. Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury. Pediatr Res. 2023;94(6):1921\u201328.","journal-title":"Pediatr Res"},{"key":"8104_CR55","doi-asserted-by":"crossref","unstructured":"Kohli-Lynch M, Russell NJ, Seale AC, Dangor Z, Tann CJ, Baker CJ, et al. Neurodevelopmental impairment in Children after group B Streptococcal disease worldwide: systematic review and meta-analyses. Clin Infect Dis. 2017;65(suppl_2):S190\u2013s199.","DOI":"10.1093\/cid\/cix663"},{"key":"8104_CR56","doi-asserted-by":"crossref","unstructured":"Tavares T, Pinho L, Bonif\u00e1cio Andrade E. Group B Streptococcal neonatal meningitis. Clin Microbiol Rev. 2022;35(2):e0007921.","DOI":"10.1128\/cmr.00079-21"},{"key":"8104_CR57","doi-asserted-by":"crossref","unstructured":"Ku LC, Boggess KA. Cohen-Wolkowiez M: Bacterial meningitis in infants. Clin Perinatol. 2015;42(1):29\u201345, vii-viii.","DOI":"10.1016\/j.clp.2014.10.004"},{"key":"8104_CR58","unstructured":"Bundy LM, Rajnik M, Noor A Neonatal Meningitis. in: StatPearls. edn. Treasure Island (FL) ineligible companies. Disclosure: Michael Rajnik declares no relevant financial relationships with ineligible companies. Disclosure: Asif Noor declares no relevant financial relationships with ineligible companies.: StatPearls Publishing, Copyright \u00a9 2025, StatPearls Publishing LLC, 2025."},{"key":"8104_CR59","doi-asserted-by":"publisher","first-page":"820365","DOI":"10.3389\/fmicb.2022.820365","volume":"13","author":"A Furuta","year":"2022","unstructured":"Furuta A, Brokaw A, Manuel G, Dacanay M, Marcell L, Seepersaud R, et al. Bacterial and Host determinants of group B Streptococcal infection of the Neonate and infant. Front Microbiol. 2022;13:820365.","journal-title":"Front Microbiol"},{"key":"8104_CR60","doi-asserted-by":"crossref","unstructured":"van der Flier M. Neonatal meningitis: small babies, big problem. Lancet Child & adolescent health. 2021;5(6):386\u201387.","DOI":"10.1016\/S2352-4642(21)00092-4"},{"key":"8104_CR61","doi-asserted-by":"publisher","first-page":"849372","DOI":"10.3389\/fnins.2022.849372","volume":"16","author":"Y He","year":"2022","unstructured":"He Y, Zhang Y, Li F, Shi Y. White matter injury in preterm infants: pathogenesis and potential therapy from the aspect of the Gut-brain axis. Front. Neurosci. 2022;16:849372.","journal-title":"Front. Neurosci"},{"issue":"6","key":"8104_CR62","doi-asserted-by":"publisher","first-page":"946","DOI":"10.2967\/jnumed.106.038539","volume":"48","author":"S Kannan","year":"2007","unstructured":"Kannan S, Saadani-Makki F, Muzik O, Chakraborty P, Mangner TJ, Janisse J, et al. Microglial activation in perinatal rabbit brain induced by intrauterine inflammation: detection with 11C-(R)-PK11195 and small-animal PET. J Nucl Med : Off Publ, Soc Nucl Med. 2007;48(6):946\u201354.","journal-title":"J Nucl Med : Off Publ, Soc Nucl Med"},{"issue":"1","key":"8104_CR63","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s12035-013-8433-7","volume":"48","author":"F Dal-Pizzol","year":"2013","unstructured":"Dal-Pizzol F, Rojas HA, dos Santos EM, Vuolo F, Constantino L, Feier G, et al. Matrix metalloproteinase-2 and metalloproteinase-9 activities are associated with blood-brain barrier dysfunction in an animal model of severe sepsis. Mol Neurobiol. 2013;48(1):62\u201370.","journal-title":"Mol Neurobiol"},{"key":"8104_CR64","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12974-015-0346-0","volume":"12","author":"SJ O\u2019Carroll","year":"2015","unstructured":"O\u2019Carroll SJ, Kho DT, Wiltshire R, Nelson V, Rotimi O, Johnson R, et al. Pro-inflammatory TNF\u03b1 and IL-1\u03b2 differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. J Neuroinflammation. 2015;12:131.","journal-title":"J Neuroinflammation"},{"issue":"Pt 12","key":"8104_CR65","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1099\/jmm.0.059840-0","volume":"62","author":"T Barichello","year":"2013","unstructured":"Barichello T, Fagundes GD, Generoso JS, Elias SG, Sim\u00f5es LR, Teixeira AL. Pathophysiology of neonatal acute bacterial meningitis. J Med Microbiol. 2013;62(Pt 12):1781\u201389.","journal-title":"J Med Microbiol"},{"issue":"2","key":"8104_CR66","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s11011-020-00624-0","volume":"36","author":"Y Akyuva","year":"2021","unstructured":"Akyuva Y, Naz\u0131ro\u011flu M, Y\u0131ld\u0131zhan K. Selenium prevents interferon-gamma induced activation of TRPM2 channel and inhibits inflammation, mitochondrial oxidative stress, and apoptosis in microglia. Metabolic Brain Disease. 2021;36(2):285\u201398.","journal-title":"Metabolic Brain Disease"},{"key":"8104_CR67","doi-asserted-by":"publisher","first-page":"663","DOI":"10.3389\/fphar.2019.00663","volume":"10","author":"FA Shah","year":"2019","unstructured":"Shah FA, Kury LA, Li T, Zeb A, Koh PO, Liu F, et al. Polydatin attenuates neuronal loss via reducing neuroinflammation and oxidative stress in rat MCAO models. Front Pharmacol. 2019;10:663.","journal-title":"Front Pharmacol"},{"key":"8104_CR68","doi-asserted-by":"publisher","first-page":"152922","DOI":"10.1016\/j.phymed.2019.152922","volume":"59","author":"K Zhou","year":"2019","unstructured":"Zhou K, Chen J, Wu J, Wu Q, Jia C, Xu YXZ, et al. Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2\/STAT3\/Drp1-dependent mitochondrial fission in microglia. Phytomed: Int J Phytotherapy Phytopharmacology. 2019;59:152922.","journal-title":"Phytomed: Int J Phytotherapy Phytopharmacology"},{"key":"8104_CR69","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.pneurobio.2015.11.002","volume":"136","author":"van Tilborg E","year":"2016","unstructured":"van Tilborg E, Heijnen CJ, Benders MJ, van Bel F, Fleiss B, Gressens P, et al. Impaired oligodendrocyte maturation in preterm infants: potential therapeutic targets. Prog Neurobiol. 2016;136:28\u201349.","journal-title":"Prog Neurobiol"},{"key":"8104_CR70","doi-asserted-by":"publisher","first-page":"106561","DOI":"10.1016\/j.nbd.2024.106561","volume":"198","author":"P Cai","year":"2024","unstructured":"Cai P, Li W, Xu Y, Wang H. Drp1 and neuroinflammation: deciphering the interplay between mitochondrial dynamics imbalance and inflammation in neurodegenerative diseases. Neurobiol Disease. 2024;198:106561.","journal-title":"Neurobiol Disease"},{"issue":"2","key":"8104_CR71","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/nm1362","volume":"12","author":"T Kawano","year":"2006","unstructured":"Kawano T, Anrather J, Zhou P, Park L, Wang G, Frys KA, et al. Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity. Nat Med. 2006;12(2):225\u201329.","journal-title":"Nat Med"},{"key":"8104_CR72","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.freeradbiomed.2018.02.036","volume":"118","author":"R Socodato","year":"2018","unstructured":"Socodato R, Portugal CC, Rodrigues A, Henriques J, Rodrigues C, Figueira C, et al. Redox tuning of Ca(2+) signaling in microglia drives glutamate release during hypoxia. Free Radical Biol Med. 2018;118:137\u201349.","journal-title":"Free Radical Biol Med"},{"key":"8104_CR73","doi-asserted-by":"crossref","unstructured":"Sousa AQ, Cavalcante DIM, Franco LM, Ara\u00fajo FMC, Sousa ET, Valen\u00e7a-Junior JT, et al. Postmortem Findings 7 Neonates Congenital Zika Virus Infect. Emerging Infect Dis. 2017;23(7):1164\u201367.","DOI":"10.3201\/eid2307.162019"},{"issue":"10","key":"8104_CR74","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1002\/stem.3425","volume":"39","author":"D Brunetti","year":"2021","unstructured":"Brunetti D, Dykstra W, Le S, Zink A, Prigione A. Mitochondria in neurogenesis: Implications for mitochondrial diseases. STEM Cells (Dayt, Ohio). 2021;39(10):1289\u201397.","journal-title":"STEM Cells (Dayt, Ohio)"},{"key":"8104_CR75","doi-asserted-by":"crossref","unstructured":"Valenti D, Vacca RA. Brain mitochondrial bioenergetics in genetic neurodevelopmental disorders: focus on down, Rett and fragile X syndromes. Int J Mol Sci. 2023;24(15).","DOI":"10.3390\/ijms241512488"},{"key":"8104_CR76","doi-asserted-by":"crossref","unstructured":"Tripathi K, Ben-Shachar D. Mitochondria in the central nervous system in health and disease: the puzzle of the therapeutic potential of mitochondrial transplantation. Cells. 2024;13(5).","DOI":"10.3390\/cells13050410"},{"issue":"6505","key":"8104_CR77","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1126\/science.aba9760","volume":"369","author":"R Iwata","year":"2020","unstructured":"Iwata R, Casimir P, Vanderhaeghen P. Mitochondrial dynamics in postmitotic cells regulate neurogenesis. Sci (New Y, NY). 2020;369(6505):858\u201362.","journal-title":"Sci (New Y, NY)"},{"issue":"3","key":"8104_CR78","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1007\/s12035-023-03644-w","volume":"61","author":"Q Duan","year":"2024","unstructured":"Duan Q, Zheng H, Qin Y, Yan J, Wang J, Burgess SM, et al. Stat3 has a different role in Axon growth during development than it Does in Axon regeneration after injury. Mol Neurobiol. 2024;61(3):1753\u201368.","journal-title":"Mol Neurobiol"},{"key":"8104_CR79","doi-asserted-by":"publisher","first-page":"103859","DOI":"10.1016\/j.redox.2025.103859","volume":"86","author":"N Ahmed Selim","year":"2025","unstructured":"Ahmed Selim N, Wojtovich AP. Mitochondrial membrane potential and compartmentalized signaling: calcium, ROS, and beyond. Redox Biol. 2025;86:103859.","journal-title":"Redox Biol"},{"key":"8104_CR80","doi-asserted-by":"publisher","first-page":"899502","DOI":"10.3389\/fonc.2022.899502","volume":"12","author":"M Peng","year":"2022","unstructured":"Peng M, Huang Y, Zhang L, Zhao X, Hou Y. Targeting mitochondrial oxidative phosphorylation eradicates acute myeloid leukemic stem cells. Front Oncol. 2022;12:899502.","journal-title":"Front Oncol"},{"issue":"4\u20136","key":"8104_CR81","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1089\/ars.2021.0137","volume":"37","author":"E Gore","year":"2022","unstructured":"Gore E, Duparc T, Genoux A, Perret B, Najib S, Martinez LO. The Multifaceted ATPase Inhibitory factor 1 (IF1) in energy metabolism reprogramming and mitochondrial dysfunction: a New player in age-associated disorders? Antioxid Redox Signal. 2022;37(4\u20136):370\u201393.","journal-title":"Antioxid Redox Signal"},{"key":"8104_CR82","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.2147\/DDDT.S386974","volume":"17","author":"X Nie","year":"2023","unstructured":"Nie X, Dong X, Hu Y, Xu F, Hu C, Shu C. Coenzyme Q10 stimulate reproductive vatality. Drug Des Devel Ther. 2023;17:2623\u201337.","journal-title":"Drug Des Devel Ther"},{"key":"8104_CR83","doi-asserted-by":"crossref","unstructured":"Manzar H, Abdulhussein D, Yap TE, Cordeiro MF. Cellular consequences of Coenzyme Q10 deficiency in neurodegeneration of the Retina and brain. Int J Mol Sci. 2020;21(23).","DOI":"10.3390\/ijms21239299"},{"issue":"2","key":"8104_CR84","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1093\/toxres\/tfad012","volume":"12","author":"SEN Chali","year":"2023","unstructured":"Chali SEN, Khanbabaei R, Juybari AAD, Fatahi E, Kalai RB. Coenzyme Q10 treatment and diazinon exposure in parental male rats: effects of the exposure on their neonatal brains. Toxicol Res (Camb). 2023;12(2):264\u201369.","journal-title":"Toxicol Res (Camb)"},{"key":"8104_CR85","doi-asserted-by":"crossref","unstructured":"M\u00fcnch J, Prasuhn J, Laugwitz L, Fung CW, Chung BH, Bellusci M, et al. Neuroimaging in primary Coenzyme-Q(10)-deficiency disorders. Antioxid (Basel). 2023;12(3).","DOI":"10.3390\/antiox12030718"},{"key":"8104_CR86","doi-asserted-by":"publisher","first-page":"599792","DOI":"10.3389\/fcell.2020.599792","volume":"8","author":"H Jung","year":"2020","unstructured":"Jung H, Kim SY, Canbakis Cecen FS, Cho Y, Kwon SK. Dysfunction of mitochondrial Ca(2+) regulatory machineries in brain aging and neurodegenerative diseases. Front. Cell Dev. Biol. 2020;8:599792.","journal-title":"Front. Cell Dev. Biol"},{"key":"8104_CR87","doi-asserted-by":"crossref","unstructured":"Sayehmiri F, Motamedi F, Batool Z, Naderi N, Shaerzadeh F, Zoghi A, et al. Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer\u2019s disease. CNS Neurosci Ther. 2024;30(8):e14897.","DOI":"10.1111\/cns.14897"},{"issue":"1","key":"8104_CR88","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s10142-025-01530-3","volume":"25","author":"S Gupta","year":"2025","unstructured":"Gupta S, Kishore A, Rishi V, Aggarwal A. Mitochondria and its epigenetic dynamics: insight into synaptic regulation and synaptopathies. Funct Integr Genomics. 2025;25(1):26.","journal-title":"Funct Integr Genomics"},{"key":"8104_CR89","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.mito.2021.11.007","volume":"62","author":"Z Dong","year":"2022","unstructured":"Dong Z, Yao X. Insight of the role of mitochondrial calcium homeostasis in hepatic insulin resistance. Mitochondrion. 2022;62:128\u201338.","journal-title":"Mitochondrion"},{"key":"8104_CR90","doi-asserted-by":"publisher","first-page":"102322","DOI":"10.1016\/j.ceca.2020.102322","volume":"93","author":"S Feno","year":"2021","unstructured":"Feno S, Rizzuto R, Raffaello A, Vecellio Reane D. The molecular complexity of the mitochondrial calcium uniporter. Cell Calcium. 2021;93:102322.","journal-title":"Cell Calcium"},{"key":"8104_CR91","doi-asserted-by":"crossref","unstructured":"Tsai CW, Liu TY, Chao FY, Tu YC, Rodriguez MX, Van Keuren AM, et al. Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex. Proc Natl Acad Sci U S A. 2023;120(16):e2217665120.","DOI":"10.1073\/pnas.2217665120"},{"key":"8104_CR92","doi-asserted-by":"crossref","unstructured":"Wu W, Shen Q, Zhang R, Qiu Z, Wang Y, Zheng J, et al. The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter. Embo J. 2020;39(19):e104285.","DOI":"10.15252\/embj.2019104285"},{"key":"8104_CR93","doi-asserted-by":"crossref","unstructured":"Singh R, Bartok A, Paillard M, Tyburski A, Elliott M, Hajn\u00f3czky G. Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients. Sci Adv. 2022;8(11):eabj 4716.","DOI":"10.1126\/sciadv.abj4716"},{"key":"8104_CR94","doi-asserted-by":"publisher","first-page":"176003","DOI":"10.1016\/j.ejphar.2023.176003","volume":"957","author":"Q You","year":"2023","unstructured":"You Q, X-B L, Liu N, Du J, Ma L, J-M Y, et al. Yu J-q: neuroprotective strategies for neonatal hypoxic-ischemic brain damage: current status and challenges. Eur J Pharmacol. 2023;957:176003.","journal-title":"Eur J Pharmacol"},{"key":"8104_CR95","doi-asserted-by":"crossref","unstructured":"Murphy E, Eisner DA. How does mitochondrial Ca2+ change during ischemia and reperfusion? Implications for activation of the permeability transition pore. J Gen Physiol. 2025;157(1).","DOI":"10.1085\/jgp.202313520"},{"key":"8104_CR96","doi-asserted-by":"publisher","first-page":"102386","DOI":"10.1016\/j.ceca.2021.102386","volume":"96","author":"A Takeuchi","year":"2021","unstructured":"Takeuchi A, Matsuoka S. Minor contribution of NCX to Na(+)-Ca(2+) exchange activity in brain mitochondria. Cell Calcium. 2021;96:102386.","journal-title":"Cell Calcium"},{"issue":"1","key":"8104_CR97","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/s42003-021-02114-0","volume":"4","author":"A Stavsky","year":"2021","unstructured":"Stavsky A, Stoler O, Kostic M, Katoshevsky T, Assali EA, Savic I, et al. Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation. Commun Biol. 2021;4(1):666.","journal-title":"Commun Biol"},{"key":"8104_CR98","doi-asserted-by":"publisher","first-page":"1226630","DOI":"10.3389\/fncel.2023.1226630","volume":"17","author":"RJ Novorolsky","year":"2023","unstructured":"Novorolsky RJ, Kasheke GDS, Hakim A, Foldvari M, Dorighello GG, Sekler I, et al. Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery. Front Cell Neurosci. 2023;17:1226630.","journal-title":"Front Cell Neurosci"},{"issue":"5","key":"8104_CR99","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/s10735-025-10601-5","volume":"56","author":"T Cheng","year":"2025","unstructured":"Cheng T, Du S, Cao Y, Lu Z, Xu Y. Neuroprotection in neonatal hypoxia-ischaemia: melatonin targets NCX1 to inhibit mitochondrial autophagy via the PINK1-Parkin pathway. J Mol Histol. 2025;56(5):313.","journal-title":"J Mol Histol"},{"key":"8104_CR100","doi-asserted-by":"publisher","first-page":"102453","DOI":"10.1016\/j.ceca.2021.102453","volume":"98","author":"D Lim","year":"2021","unstructured":"Lim D, Dematteis G, Tapella L, Genazzani AA, Cal\u00ec T, Brini M, et al. Ca(2+) handling at the mitochondria-ER contact sites in neurodegeneration. Cell Calcium. 2021;98:102453.","journal-title":"Cell Calcium"},{"issue":"1","key":"8104_CR101","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s12964-024-02014-w","volume":"23","author":"X Li","year":"2025","unstructured":"Li X, Zhao X, Qin Z, Li J, Sun B, Liu L. Regulation of calcium homeostasis in endoplasmic reticulum-mitochondria crosstalk: implications for skeletal muscle atrophy. Cell Commun Signal. 2025;23(1):17.","journal-title":"Cell Commun Signal"},{"key":"8104_CR102","doi-asserted-by":"publisher","first-page":"251525642413128","DOI":"10.1177\/25152564241312807","volume":"8","author":"E Navarro","year":"2025","unstructured":"Navarro E, Montesinos J. Mitochondria-associated Endoplasmic reticulum membranes in microglia: one contact site to rule them all. Contact. 2025;8:25152564241312807.","journal-title":"Contact"},{"key":"8104_CR103","doi-asserted-by":"crossref","unstructured":"St V, Stepanova AA, Ratner V, Neginskaya M, Niatsetskaya Z, Sosunov S, et al. Mitochondrial dysfunction and permeability transition in neonatal brain and Lung injuries. Cells. 2021;10(3).","DOI":"10.3390\/cells10030569"},{"issue":"5","key":"8104_CR104","first-page":"1198","volume":"34","author":"B Robinson","year":"2021","unstructured":"Robinson B, Gu Q, Kanungo J. Antidepressant actions of ketamine: potential role of L-Type calcium channels. Chem Res Toxicol. 2021;34(5):1198\u2013207.","journal-title":"Chem ResearchToxicol"},{"key":"8104_CR105","doi-asserted-by":"publisher","first-page":"118194","DOI":"10.1016\/j.bmc.2025.118194","volume":"124","author":"P Li","year":"2025","unstructured":"Li P, Wang J, Wang M, Chen X, Zhu H, Dong M. Development of GluN2A NMDA receptor positive allosteric modulators: recent advances and perspectives. Bioorg Med Chem. 2025;124:118194.","journal-title":"Bioorg Med Chem"},{"key":"8104_CR106","doi-asserted-by":"crossref","unstructured":"Ehinger R, Kuret A, Matt L, Frank N, Wild K, Kabagema-Bilan C, et al. Slack K(+) channels attenuate NMDA-induced excitotoxic brain damage and neuronal cell death. Faseb J. 2021;35(5):e21568.","DOI":"10.1096\/fj.202002308RR"},{"issue":"11","key":"8104_CR107","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.1111\/j.1460-9568.2006.05188.x","volume":"24","author":"GG Xing","year":"2006","unstructured":"Xing GG, Wang R, Yang B, Zhang D. Postnatal switching of NMDA receptor subunits from NR2B to NR2A in rat facial motor neurons. Eur J Neurosci. 2006;24(11):2987\u201392.","journal-title":"Eur J Neurosci"},{"key":"8104_CR108","doi-asserted-by":"publisher","first-page":"1476856","DOI":"10.3389\/fncel.2024.1476856","volume":"18","author":"J Zhou","year":"2024","unstructured":"Zhou J, Lu X, Wang H. The underlying molecular mechanisms of Fyn in neonatal hypoxic-ischaemic encephalopathy. Front Cell Neurosci. 2024;18:1476856.","journal-title":"Front Cell Neurosci"},{"issue":"10","key":"8104_CR109","doi-asserted-by":"publisher","first-page":"3165","DOI":"10.1113\/JP274006","volume":"595","author":"M Faouzi","year":"2017","unstructured":"Faouzi M, Kilch T, Horgen FD, Fleig A, Penner R. The TRPM7 channel kinase regulates store-operated calcium entry. J Physiol. 2017;595(10):3165\u201380.","journal-title":"J Physiol"},{"issue":"8","key":"8104_CR110","doi-asserted-by":"publisher","first-page":"2475","DOI":"10.7150\/ijbs.80672","volume":"19","author":"S Zhang","year":"2023","unstructured":"Zhang S, Zhao J, Wu M, Zhou Y, Wu X, Du A, et al. Over-activation of TRPM2 ion channel accelerates blood-spinal cord barrier destruction in diabetes combined with spinal cord injury rat. Int J Biol Sci. 2023;19(8):2475\u201394.","journal-title":"Int J Biol Sci"},{"key":"8104_CR111","doi-asserted-by":"publisher","first-page":"102530","DOI":"10.1016\/j.pneurobio.2023.102530","volume":"231","author":"P Ye","year":"2023","unstructured":"Ye P, Fang Q, Hu X, Zou W, Huang M, Ke M, et al. TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis. Prog Neurobiol. 2023;231:102530.","journal-title":"Prog Neurobiol"},{"key":"8104_CR112","doi-asserted-by":"crossref","unstructured":"A FV, M R, I S, Andreti\u0107 Waldowski. Influence of Redox and dopamine regulation in cocaine-induced phenotypes using Drosophila. Antioxid (Basel). 2023;12(4).","DOI":"10.3390\/antiox12040933"},{"key":"8104_CR113","doi-asserted-by":"crossref","unstructured":"Cie\u015blik M, Zawadzka A, Czapski GA, Wilkaniec A, Adamczyk A. Developmental stage-dependent changes in mitochondrial function in the brain of offspring following prenatal Maternal immune activation. Int J Mol Sci. 2023;24(8).","DOI":"10.3390\/ijms24087243"},{"key":"8104_CR114","doi-asserted-by":"publisher","first-page":"106550","DOI":"10.1016\/j.nbd.2024.106550","volume":"199","author":"A Rajan","year":"2024","unstructured":"Rajan A, Fame RM. Brain development and bioenergetic changes. Neurobiol Disease. 2024;199:106550.","journal-title":"Neurobiol Disease"},{"issue":"1","key":"8104_CR115","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1038\/s41392-024-01839-8","volume":"9","author":"Y Zong","year":"2024","unstructured":"Zong Y, Li H, Liao P, Chen L, Pan Y, Zheng Y, et al. Mitochondrial dysfunction: mechanisms and advances in therapy. Signal Transduct Target Ther. 2024;9(1):124.","journal-title":"Signal Transduct Target Ther"},{"key":"8104_CR116","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.freeradbiomed.2022.04.015","volume":"186","author":"KM Prutton","year":"2022","unstructured":"Prutton KM, Marentette JO, Leifheit BA, Esquer H, LaBarbera DV, Anderson CC, et al. Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21. Free Radical Biol Med. 2022;186:32\u201342.","journal-title":"Free Radical Biol Med"},{"key":"8104_CR117","doi-asserted-by":"crossref","unstructured":"Wang Q, Wang W, Wang Y, Yun J, Zhang Y, Zhao F. Exogenous MnSO(4) improves productivity of degenerated volvariella volvacea by regulating antioxidant activity. J Fungi (Basel). 2024;10(12).","DOI":"10.3390\/jof10120825"},{"issue":"9","key":"8104_CR118","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1038\/s41418-018-0230-4","volume":"26","author":"Q Zhao","year":"2019","unstructured":"Zhao Q, Lu D, Wang J, Liu B, Cheng H, Mattson MP. Cheng A: calcium dysregulation mediates mitochondrial and neurite outgrowth abnormalities in SOD2 deficient embryonic cerebral cortical neurons. Cell Death Differ. 2019;26(9):1600\u201314.","journal-title":"Cell Death Differ"},{"key":"8104_CR119","doi-asserted-by":"crossref","unstructured":"Gao L, Zhang C, Zheng Y, Wu D, Chen X, Lan H, et al. Glycine regulates lipid peroxidation promoting porcine oocyte maturation and early embryonic development. J Anim Sci. 2023;101.","DOI":"10.1093\/jas\/skac425"},{"key":"8104_CR120","doi-asserted-by":"publisher","first-page":"110654","DOI":"10.1016\/j.cellsig.2023.110654","volume":"106","author":"S Babaei-Abraki","year":"2023","unstructured":"Babaei-Abraki S, Karamali F, Nasr-Esfahani MH. Ferroptosis: the functions of Nrf2 in human embryonic stem cells. Cell Signal. 2023;106:110654.","journal-title":"Cell Signal"},{"key":"8104_CR121","doi-asserted-by":"crossref","unstructured":"Cardozo G, Mastrogiovanni M, Zeida A, Viera N, Radi R, Reyes AM, et al. Mitochondrial Peroxiredoxin 3 is rapidly Oxidized and hyperoxidized by fatty acid hydroperoxides. Antioxid (Basel). 2023;12(2).","DOI":"10.3390\/antiox12020408"},{"key":"8104_CR122","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.neuroscience.2024.03.019","volume":"545","author":"X Liu","year":"2024","unstructured":"Liu X, Hong E, Xie J, Li J, Ding B, Chen Y, et al. Txnrd2 attenuates early brain injury by inhibition of oxidative stress and Endoplasmic reticulum stress via Trx2\/Prx3 pathway after intracerebral hemorrhage in rats. Neuroscience. 2024;545:158\u201370.","journal-title":"Neuroscience"},{"issue":"1","key":"8104_CR123","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1186\/s12906-023-03967-0","volume":"23","author":"M Li","year":"2023","unstructured":"Li M, Zhang J, Jiang L, Wang W, Feng X, Liu M, et al. Neuroprotective effects of morroniside from cornus officinalis sieb. Et zucc against Parkinson\u2019s disease via inhibiting oxidative stress and ferroptosis. BMC Complement Med Ther. 2023;23(1):218.","journal-title":"BMC Complement Med Ther"},{"issue":"11","key":"8104_CR124","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1038\/s41419-024-07216-1","volume":"15","author":"SK Jang","year":"2024","unstructured":"Jang SK, Ahn SH, Kim G, Kim S, Hong J, Park KS, et al. Inhibition of VDAC1 oligomerization blocks cysteine deprivation-induced ferroptosis via mitochondrial ROS suppression. Cell Death Dis. 2024;15(11):811.","journal-title":"Cell Death Dis"},{"issue":"3","key":"8104_CR125","doi-asserted-by":"publisher","first-page":"403","DOI":"10.3724\/abbs.2024168","volume":"57","author":"H Dong","year":"2024","unstructured":"Dong H, Sun K, Wang X, Cui M, Ma Y, Li K, et al. Repurposed genipin targeting UCP2 exhibits antitumor activity through inducing ferroptosis in glioblastoma. Acta Biochim. Biophys. Sin. (Shanghai). 2024;57(3):403\u201314.","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"key":"8104_CR126","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1146\/annurev-pathmechdis-012419-032711","volume":"15","author":"DC Chan","year":"2020","unstructured":"Chan DC. Mitochondrial dynamics and its Involvement in disease. Annu Rev Pathol. 2020;15:235\u201359.","journal-title":"Annu Rev Pathol"},{"issue":"10","key":"8104_CR127","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1038\/s41580-023-00629-4","volume":"24","author":"PE Czabotar","year":"2023","unstructured":"Czabotar PE, Garcia-Saez AJ. Mechanisms of BCL-2 family proteins in mitochondrial apoptosis. Nat Rev Mol Cell Biol. 2023;24(10):732\u201348.","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"10","key":"8104_CR128","doi-asserted-by":"publisher","first-page":"119317","DOI":"10.1016\/j.bbamcr.2022.119317","volume":"1869","author":"P Wolf","year":"2022","unstructured":"Wolf P, Schoeniger A, Edlich F. Pro-apoptotic complexes of BAX and BAK on the outer mitochondrial membrane. Biochim Biophys Acta Mol Cell Res. 2022;1869(10):119317.","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"issue":"1","key":"8104_CR129","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1038\/s41420-023-01763-w","volume":"10","author":"L Lindenboim","year":"2024","unstructured":"Lindenboim L, Zohar H, Gundersen GG, Worman HJ, Stein R. LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins. Cell Death Discov. 2024;10(1):29.","journal-title":"Cell Death Discov"},{"issue":"5","key":"8104_CR130","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1038\/nrm2153","volume":"8","author":"SJ Riedl","year":"2007","unstructured":"Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol. 2007;8(5):405\u201313.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"8104_CR131","doi-asserted-by":"publisher","first-page":"109703","DOI":"10.1016\/j.intimp.2023.109703","volume":"115","author":"L Niu","year":"2023","unstructured":"Niu L, Wang L, He X, Fan Q, Chen M, Qiao Y, et al. Renoprotective effects of ferulic acid mediated by AMPK\u03b11 against lipopolysaccharide-induced damage. Int Immunopharmacol. 2023;115:109703.","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"8104_CR132","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/s41420-022-00981-y","volume":"8","author":"D Wu","year":"2022","unstructured":"Wu D, Yan L, Zheng C, Ren X, Pan Y, Huang S, et al. Akt-GSK3\u03b2-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress. Cell Death Discov. 2022;8(1):168.","journal-title":"Cell Death Discov"},{"key":"8104_CR133","doi-asserted-by":"crossref","unstructured":"Mueller F, Friese A, Pathe C, da Silva RC, Rodriguez KB, Musacchio A, et al. Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization. Sci Adv. 2021;7(3).","DOI":"10.1126\/sciadv.abc8590"},{"issue":"1","key":"8104_CR134","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/s41420-024-01955-y","volume":"10","author":"S Zhao","year":"2024","unstructured":"Zhao S, Mo G, Wang Q, Xu J, Yu S, Huang Z, et al. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Cell Death Discov. 2024;10(1):182.","journal-title":"Cell Death Discov"},{"issue":"1","key":"8104_CR135","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1038\/s41467-025-56342-7","volume":"16","author":"M Andoh","year":"2025","unstructured":"Andoh M, Shinoda N, Taira Y, Araki T, Kasahara Y, Takeuchi H, et al. Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia. Nat Commun. 2025;16(1):918.","journal-title":"Nat Commun"},{"key":"8104_CR136","doi-asserted-by":"crossref","unstructured":"Bas J, Nguyen T, Gillet G. Involvement of Bcl-xL in neuronal function and development. Int J Mol Sci. 2021;22(6).","DOI":"10.3390\/ijms22063202"},{"key":"8104_CR137","doi-asserted-by":"crossref","unstructured":"Guo R, Wang SS, Jiang XY, Zhang Y, Guo Y, Cui HY, et al. CHK2 promotes metabolic stress-induced autophagy through ULK1 phosphorylation. Antioxid (Basel). 2022;11(6).","DOI":"10.3390\/antiox11061166"},{"issue":"4","key":"8104_CR138","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1667\/RADE-24-00087.1","volume":"203","author":"H Peng","year":"2025","unstructured":"Peng H, Cui B, Wei J, Yuan M, Liu W, Shi J, et al. Timosaponin AIII enhances radiosensitivity in breast cancer through Induction of ROS-Mediated DNA damage and apoptosis. Radiat Res. 2025;203(4):257\u201370.","journal-title":"Radiat Res"},{"key":"8104_CR139","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.redox.2014.11.006","volume":"4","author":"HM Ni","year":"2015","unstructured":"Ni HM, Williams JA, Ding WX. Mitochondrial dynamics and mitochondrial quality control. Redox Biol. 2015;4:6\u201313.","journal-title":"Redox Biol"},{"issue":"5","key":"8104_CR140","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.4103\/NRR.NRR-D-24-01422","volume":"21","author":"Z Yang","year":"2026","unstructured":"Yang Z, Luo Y, Yang Z, Liu Z, Li M, Wu X, et al. Mitochondrial dynamics dysfunction and neurodevelopmental disorders: from pathological mechanisms to clinical translation. Neural Regen Res. 2026;21(5):1926\u201346.","journal-title":"Neural Regen Res"},{"issue":"1","key":"8104_CR141","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s40104-025-01180-2","volume":"16","author":"F Wen","year":"2025","unstructured":"Wen F, Gao J, Zhang G, Guo S, Zhang X, Han S, et al. ROS-DRP1-mediated excessive mitochondrial fission and autophagic flux inhibition contribute to heat stress-induced apoptosis in goat Sertoli cells. J Anim Sci Biotechnol. 2025;16(1):58.","journal-title":"J Anim Sci Biotechnol"},{"key":"8104_CR142","doi-asserted-by":"crossref","unstructured":"Na SB, Seo BJ, Hong TK, Oh SY, Hong YJ, Song JH, et al. Altered mitochondrial function and accelerated aging phenotype in neural stem cells derived from Dnm1l knockout embryonic stem cells. Int J Mol Sci. 2023;24(18).","DOI":"10.3390\/ijms241814291"},{"key":"8104_CR143","doi-asserted-by":"crossref","unstructured":"Jage\u010di\u0107 D, Petrovi\u0107 DJ, \u0160imuni\u0107 I, Isakovi\u0107 J, Mitre\u010di\u0107 D. The oxygen and glucose deprivation of immature cells of the nervous system exerts distinct effects on mitochondria, mitophagy, and autophagy, depending on the cells\u2019 differentiation stage. Brain Sci. 2023;13(6).","DOI":"10.3390\/brainsci13060910"},{"key":"8104_CR144","doi-asserted-by":"crossref","unstructured":"Xu Y, Wang P, Hu T, Ning K, Bao Y. Notoginsenoside R1 attenuates H\/R injury in H9c2 cells by maintaining mitochondrial homeostasis. Curr Issues Mol Biol. 2025;47(1).","DOI":"10.3390\/cimb47010044"},{"issue":"3","key":"8104_CR145","doi-asserted-by":"publisher","first-page":"106270","DOI":"10.1016\/j.isci.2023.106270","volume":"26","author":"S Shahin","year":"2023","unstructured":"Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, et al. MFN1 augmentation prevents retinal degeneration in a charcot-marie-tooth type 2A mouse model. iScience. 2023;26(3):106270.","journal-title":"iScience"},{"issue":"12","key":"8104_CR146","doi-asserted-by":"publisher","first-page":"111384","DOI":"10.1016\/j.isci.2024.111384","volume":"27","author":"R Weil","year":"2024","unstructured":"Weil R, Laplantine E, Attailia M, Oudin A, Curic S, Yokota A, et al. Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy. iScience. 2024;27(12):111384.","journal-title":"iScience"},{"key":"8104_CR147","doi-asserted-by":"publisher","first-page":"117421","DOI":"10.1016\/j.taap.2025.117421","volume":"502","author":"Y Zhou","year":"2025","unstructured":"Zhou Y, Huang Y, Liang H, Yang X, Zhang S, Huang Y, et al. Resveratrol inhibits autophagy in cardiomyocytes subjected anoxia\/reoxygenation injury: involved in VDAC1\/PINK1\/Parkin pathway. Toxicol Appl Pharmacol. 2025;502:117421.","journal-title":"Toxicol Appl Pharmacol"},{"key":"8104_CR148","doi-asserted-by":"publisher","first-page":"111327","DOI":"10.1016\/j.cbi.2024.111327","volume":"406","author":"J Hu","year":"2025","unstructured":"Hu J, Yang B, Tao Z, Chen J, Zhang X, Wang S, et al. The role of HIF-1\u03b1\/BNIP3\/mitophagy in acrylonitrile-induced neuronal death in HT22 cells and mice: a potential neuroprotection target. Chem Biol Interact. 2025;406:111327.","journal-title":"Chem Biol Interact"},{"issue":"4","key":"8104_CR149","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.3233\/JAD-240401","volume":"99","author":"R Pluta","year":"2024","unstructured":"Pluta R, Bogucka-Kocka A, Bogucki J, Kocki J, Czuczwar SJ. Apoptosis, autophagy, and mitophagy genes in the CA3 area in an ischemic model of Alzheimer\u2019s disease with 2-year survival. J Alzheimers Dis. 2024;99(4):1375\u201383.","journal-title":"J Alzheimers Dis"},{"issue":"11","key":"8104_CR150","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1016\/j.cmet.2022.10.008","volume":"34","author":"M Picard","year":"2022","unstructured":"Picard M, Shirihai OS. Mitochondrial signal transduction. Cell Metab. 2022;34(11):1620\u201353.","journal-title":"Cell Metab"},{"issue":"51","key":"8104_CR151","doi-asserted-by":"publisher","first-page":"48984","DOI":"10.1021\/acsomega.3c06617","volume":"8","author":"X Yan","year":"2023","unstructured":"Yan X, Chen X, Shan Z, Bi L. Engineering exosomes to specifically target the mitochondria of brain cells. ACS Omega. 2023;8(51):48984\u201393.","journal-title":"ACS Omega"},{"issue":"1","key":"8104_CR152","doi-asserted-by":"publisher","first-page":"113614","DOI":"10.1016\/j.yexcr.2023.113614","volume":"428","author":"A Sharma","year":"2023","unstructured":"Sharma A, Anand SK, Singh N, Dwivedi UN, Kakkar P. AMP-activated protein kinase: an energy sensor and survival mechanism in the reinstatement of metabolic homeostasis. Exp Cell Res. 2023;428(1):113614.","journal-title":"Exp Cell Res"},{"key":"8104_CR153","doi-asserted-by":"publisher","first-page":"123056","DOI":"10.1016\/j.lfs.2024.123056","volume":"357","author":"AA Bhat","year":"2024","unstructured":"Bhat AA, Moglad E, Goyal A, Afzal M, Thapa R, Almalki WH, et al. Nrf2 pathways in neuroprotection: alleviating mitochondrial dysfunction and cognitive impairment in aging. Life Sci. 2024;357:123056.","journal-title":"Life Sci"},{"issue":"23","key":"8104_CR154","doi-asserted-by":"publisher","first-page":"12021","DOI":"10.1039\/D2FO02131E","volume":"13","author":"Y Jiang","year":"2022","unstructured":"Jiang Y, Qi Y, Liu X, Fang L, Gao Y, Liu C, et al. Neuroprotective effects of fermented yak milk-derived peptide LYLKPR on H(2)O(2)-injured HT-22 cells. Food Funct. 2022;13(23):12021\u201338.","journal-title":"Food Funct"},{"issue":"7","key":"8104_CR155","doi-asserted-by":"publisher","first-page":"4102","DOI":"10.1007\/s12035-023-03832-8","volume":"61","author":"Y Wu","year":"2024","unstructured":"Wu Y, Zhu Z, Lan T, Li S, Li Y, Wang C, et al. Levomilnacipran improves lipopolysaccharide-induced dysregulation of synaptic plasticity and depression-like behaviors via activating BDNF\/TrkB mediated PI3K\/Akt\/mTOR signaling pathway. Mol Neurobiol. 2024;61(7):4102\u201315.","journal-title":"Mol Neurobiol"},{"issue":"4","key":"8104_CR156","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1007\/s10787-025-01643-y","volume":"33","author":"D Khayatan","year":"2025","unstructured":"Khayatan D, Razavi SM, Arab ZN, Nasoori H, Fouladi A, Pasha AVK, et al. Targeting mTOR with curcumin: therapeutic implications for complex diseases. Inflammopharmacology. 2025;33(4):1583\u2013616.","journal-title":"Inflammopharmacology"},{"key":"8104_CR157","doi-asserted-by":"publisher","first-page":"109965","DOI":"10.1016\/j.exer.2024.109965","volume":"245","author":"L Xu","year":"2024","unstructured":"Xu L, Xu Y, Jiang Y, Jiang J, Chen S, Sun D, et al. IP3R2 regulates apoptosis by Ca2+ transfer through mitochondria-ER contacts in hypoxic photoreceptor injury. Exp Eye Res. 2024;245:109965.","journal-title":"Exp Eye Res"},{"issue":"1","key":"8104_CR158","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/s41467-024-55758-x","volume":"16","author":"P Gatti","year":"2025","unstructured":"Gatti P, Schiavon C, Cicero J, Manor U, Germain M. Mitochondria- and ER-associated actin are required for mitochondrial fusion. Nat Commun. 2025;16(1):451.","journal-title":"Nat Commun"},{"key":"8104_CR159","doi-asserted-by":"crossref","unstructured":"Hatsuda A, Kurisu J, Fujishima K, Kawaguchi A, Ohno N, Kengaku M. Calcium signals tune AMPK activity and mitochondrial homeostasis in dendrites of developing neurons. Development. 2023;150(21).","DOI":"10.1242\/dev.201930"},{"key":"8104_CR160","doi-asserted-by":"publisher","first-page":"101175","DOI":"10.1016\/j.mtbio.2024.101175","volume":"28","author":"H Xiong","year":"2024","unstructured":"Xiong H, Qiu H, Wang C, Qiu Y, Tan S, Chen K, et al. Melatonin-loaded bioactive microspheres accelerate aged bone regeneration by formation of tunneling nanotubes to enhance mitochondrial transfer. Mater Today Bio. 2024;28:101175.","journal-title":"Mater Today Bio"},{"key":"8104_CR161","doi-asserted-by":"crossref","unstructured":"Tovar LM, Burgos CF, Y\u00e9venes GE, Moraga-Cid G, Fuentealba J, Coddou C, et al. Understanding the role of ATP release through connexins hemichannels during Neurulation. Int J Mol Sci. 2023;24(3).","DOI":"10.3390\/ijms24032159"},{"key":"8104_CR162","doi-asserted-by":"publisher","first-page":"102522","DOI":"10.1016\/j.arr.2024.102522","volume":"101","author":"R Iorio","year":"2024","unstructured":"Iorio R, Petricca S, Di Emidio G, Falone S, Tatone C. Mitochondrial extracellular vesicles (mitoEvs): emerging mediators of cell-to-cell communication in health, aging and age-related diseases. Ageing Res Rev. 2024;101:102522.","journal-title":"Ageing Res Rev"},{"issue":"Pt C","key":"8104_CR163","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.semcdb.2023.05.003","volume":"154","author":"S Ahmad","year":"2024","unstructured":"Ahmad S, Zhang XL, Ahmad A. Epigenetic regulation of pulmonary inflammation. Semin Cell Dev Biol. 2024;154(Pt C):346\u201354.","journal-title":"Semin Cell Dev Biol"},{"issue":"11","key":"8104_CR164","doi-asserted-by":"publisher","first-page":"3707","DOI":"10.7150\/thno.81981","volume":"13","author":"M Beatriz","year":"2023","unstructured":"Beatriz M, Rodrigues RJ, Vila\u00e7a R, Egas C, Pinheiro PS, Daley GQ, et al. Extracellular vesicles improve GABAergic transmission in Huntington\u2019s disease iPSC-derived neurons. Theranostics. 2023;13(11):3707\u201324.","journal-title":"Theranostics"},{"key":"8104_CR165","doi-asserted-by":"crossref","unstructured":"Peng X, Gao Y, Liu J, Shi X, Li W, Ma Y, et al. Mitochondria-derived vesicles: a promising and potential target for tumour therapy. Clin Transl Med. 2025;15(5):e70320.","DOI":"10.1002\/ctm2.70320"},{"key":"8104_CR166","first-page":"472","volume":"60","author":"P Li","year":"2026","unstructured":"Li P, Liang Z, Zeng X, Lei R, Guo S, Zhang Z, et al. Age-related GSS promoter methylation in BMSCs drives osteoporosis and the reversal by targeted GSH delivery. Bioact Mater. 2026;60:472\u201391.","journal-title":"Bioact Mater"},{"issue":"1","key":"8104_CR167","doi-asserted-by":"publisher","first-page":"3653","DOI":"10.1038\/s41467-024-48100-y","volume":"15","author":"B Guan","year":"2024","unstructured":"Guan B, Liu Y, Xie B, Zhao S, Yalikun A, Chen W, et al. Mitochondrial genome transfer drives metabolic reprogramming in adjacent colonic epithelial cells promoting TGF\u03b21-mediated tumor progression. Nat Commun. 2024;15(1):3653.","journal-title":"Nat Commun"},{"key":"8104_CR168","doi-asserted-by":"crossref","unstructured":"Nakano T, Irie K, Matsuo K, Mishima K, Nakamura Y. Molecular and cellular mechanisms of mitochondria transfer in models of central nervous system disease. J Cereb Blood Flow Metab. 2024;271678x241300223.","DOI":"10.1177\/0271678X241300223"},{"issue":"1","key":"8104_CR169","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1093\/toxsci\/kfac110","volume":"191","author":"Z Tian","year":"2023","unstructured":"Tian Z, Li J, Song L, Xie L, Li D, Xia T, et al. PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p\/PGC-1\u03b1 axis. Toxicol Sci. 2023;191(1):123\u201334.","journal-title":"Toxicol Sci"},{"key":"8104_CR170","doi-asserted-by":"crossref","unstructured":"Hees JT, Harbauer AB. Metabolic regulation of mitochondrial protein biogenesis from a neuronal perspective. Biomolecules. 2022;12(11).","DOI":"10.3390\/biom12111595"},{"issue":"1","key":"8104_CR171","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s13287-023-03274-y","volume":"14","author":"J Yang","year":"2023","unstructured":"Yang J, Liu L, Oda Y, Wada K, Ago M, Matsuda S, et al. Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer. STEM Cell Res Ther. 2023;14(1):40.","journal-title":"STEM Cell Res Ther"},{"key":"8104_CR172","doi-asserted-by":"publisher","first-page":"155275","DOI":"10.1016\/j.metabol.2022.155275","volume":"135","author":"Z Fu","year":"2022","unstructured":"Fu Z, Kim H, Morse PT, Lu MJ, H\u00fcttemann M, Cambronne XA, et al. The mitochondrial NAD(+) transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions. Metabolism. 2022;135:155275.","journal-title":"Metabolism"},{"issue":"1","key":"8104_CR173","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s13024-023-00690-9","volume":"19","author":"S Yang","year":"2024","unstructured":"Yang S, Niou ZX, Enriquez A, LaMar J, Huang JY, Ling K, et al. NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport. Mol Neurodegener. 2024;19(1):13.","journal-title":"Mol Neurodegener"},{"key":"8104_CR174","doi-asserted-by":"crossref","unstructured":"Klemmensen MM, Borrowman SH, Pearce C, Pyles B, Chandra B. Mitochondrial dysfunction in neurodegenerative disorders. Neurotherapeutics: J Am Soc Exp NeuroTherapeutics. 2024;21(1):e00292.","DOI":"10.1016\/j.neurot.2023.10.002"},{"key":"8104_CR175","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.freeradbiomed.2025.02.036","volume":"231","author":"AVS Carvalho","year":"2025","unstructured":"Carvalho AVS, Sanches EF, Ribeiro RT, Dur\u00e1n-Carabali LE, J\u00fanior OR, Muniz BD, et al. Maternal lactoferrin supplementation prevents mitochondrial and redox homeostasis dysfunction, and improves antioxidant defenses through Nrf2 and UCP2 signaling after neonatal hypoxia-ischemia. Free Radical Biol & Med. 2025;231:68\u201379.","journal-title":"Free Radical Biol & Med"},{"key":"8104_CR176","doi-asserted-by":"crossref","unstructured":"Wang L XX, Xu M, Zhao XW, Jin WB, Li YM, Qin LL, et al. BNIP3-mediated mitophagy attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting ferroptosis through P62-KEAP1-NRF2 pathway activation to maintain iron and redox homeostasis. Acta Pharmacol Sin. 2025;46(1):33\u201351.","DOI":"10.1038\/s41401-024-01365-x"},{"issue":"Pt 1","key":"8104_CR177","doi-asserted-by":"publisher","first-page":"148589","DOI":"10.1016\/j.ijbiomac.2025.148589","volume":"332","author":"A Anwar","year":"2025","unstructured":"Anwar A, Yameen D, Masood M, Parvez S, Haque MM. Neuronal nitric oxide synthase (nNOS) uncoupling in ischemic stroke: mechanisms of oxidative\/nitrosative stress and opportunities for neuroprotection: a review. Int J Biol Macromol. 2025;332(Pt 1):148589.","journal-title":"Int J Biol Macromol"},{"key":"8104_CR178","doi-asserted-by":"crossref","unstructured":"Bertozzi G, Ferrara M, Calvano M, Pascale N, Di Fazio A. Oxidative\/Nitrosative stress and brain Involvement in sepsis: a relationship supported by immunohistochemistry. Medicina (Kaunas). 2024;60(12).","DOI":"10.3390\/medicina60121949"},{"issue":"1","key":"8104_CR179","doi-asserted-by":"publisher","first-page":"6143","DOI":"10.1038\/s41467-024-50502-x","volume":"15","author":"M Liiv","year":"2024","unstructured":"Liiv M, Vaarmann A, Safiulina D, Choubey V, Gupta R, Kuum M, et al. ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in wolfram syndrome. Nat Commun. 2024;15(1):6143.","journal-title":"Nat Commun"},{"key":"8104_CR180","doi-asserted-by":"crossref","unstructured":"Pekson R, Liang FG, Axelrod JL, Lee J, Qin D, Wittig AJH, et al. The mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A. 2023;120(51):e2303713120.","DOI":"10.1073\/pnas.2303713120"},{"key":"8104_CR181","doi-asserted-by":"publisher","first-page":"106269","DOI":"10.1016\/j.nbd.2023.106269","volume":"186","author":"van Hameren G","year":"2023","unstructured":"van Hameren G, Muradov J, Minarik A, Aboghazleh R, Orr S, Cort S, et al. Mitochondrial dysfunction underlies impaired neurovascular coupling following traumatic brain injury. Neurobiol Disease. 2023;186:106269.","journal-title":"Neurobiol Disease"},{"issue":"10","key":"8104_CR182","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1161\/CIRCRESAHA.123.323882","volume":"134","author":"A Mendoza","year":"2024","unstructured":"Mendoza A, Patel P, Robichaux D, Ramirez D, Karch J. Inhibition of the mPTP and lipid peroxidation is additively protective against I\/R injury. Circ Res. 2024;134(10):1292\u2013305.","journal-title":"Circ Res"},{"issue":"9","key":"8104_CR183","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1038\/s41401-024-01292-x","volume":"45","author":"XL Jiang","year":"2024","unstructured":"Jiang XL, Zhang ZB, Feng CX, Lin CJ, Yang H, Tan LL, et al. PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy. Acta Pharmacol Sin. 2024;45(9):1809\u201320.","journal-title":"Acta Pharmacol Sin"},{"issue":"1","key":"8104_CR184","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1186\/s10020-024-00948-y","volume":"30","author":"J Zhang","year":"2024","unstructured":"Zhang J, Wang S, Zhang H, Yang X, Ren X, Wang L, et al. Drp1 acetylation mediated by CDK5-AMPK-GCN5L1 axis promotes cerebral ischemic injury via facilitating mitochondrial fission. Mol Med. 2024;30(1):173.","journal-title":"Mol Med"},{"issue":"6","key":"8104_CR185","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.4103\/1673-5374.300453","volume":"16","author":"LL Tan","year":"2021","unstructured":"Tan LL, Jiang XL, Xu LX, Li G, Feng CX, Ding X, et al. TP53-induced glycolysis and apoptosis regulator alleviates hypoxia\/ischemia-induced microglial pyroptosis and ischemic brain damage. Neural Regen Res. 2021;16(6):1037\u201343.","journal-title":"Neural Regen Res"},{"key":"8104_CR186","doi-asserted-by":"publisher","first-page":"114266","DOI":"10.1016\/j.biopha.2023.114266","volume":"159","author":"XB Lan","year":"2023","unstructured":"Lan XB, Ni YS, Liu N, Wei W, Liu Y, Yang JM, et al. Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt\/\u03b2-catenin pathway. Biomed Pharmacother. 2023;159:114266.","journal-title":"Biomed Pharmacother"},{"issue":"4","key":"8104_CR187","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1165\/rcmb.2023-0402OC","volume":"71","author":"N Starke","year":"2024","unstructured":"Starke N, Challa NVD, Yuan H, Chen S, Duncan MR, Cabrera Ranaldi E, et al. Extracellular Vesicle ASC: A Novel Mediator for Lung-Brain Axis in Preterm Brain Injury. Am J Respir Cell Mol Biol. 2024;71(4):464\u201380.","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"1","key":"8104_CR188","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1038\/s41420-024-02014-2","volume":"10","author":"L Wu","year":"2024","unstructured":"Wu L, Chang E, Zhao H, Ma D. Regulated cell death in hypoxic-ischaemic encephalopathy: recent development and mechanistic overview. Cell Death Discov. 2024;10(1):277.","journal-title":"Cell Death Discov"},{"key":"8104_CR189","doi-asserted-by":"crossref","unstructured":"Hu S, Lopez-Robles Y, Shen G, Liu E, Zhang L, Ma Q. MicroRNA210 suppresses mitochondrial metabolism and promotes microglial activation in neonatal hypoxic-ischemic brain injury. Cells. 2025;14(15).","DOI":"10.3390\/cells14151202"},{"issue":"2","key":"8104_CR190","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1038\/s41556-023-01343-1","volume":"26","author":"LE Newman","year":"2024","unstructured":"Newman LE, Weiser Novak S, Rojas GR, Tadepalle N, Schiavon CR, Grotjahn DA, et al. Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal. Nat Cell Biol. 2024;26(2):194\u2013206.","journal-title":"Nat Cell Biol"},{"issue":"1","key":"8104_CR191","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1038\/s41420-024-01953-0","volume":"10","author":"W You","year":"2024","unstructured":"You W, Knoops K, Berendschot T, Benedikter BJ, Webers CAB, Reutelingsperger CPM, et al. PGC-1a mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration. Cell Death Discov. 2024;10(1):180.","journal-title":"Cell Death Discov"},{"issue":"3","key":"8104_CR192","doi-asserted-by":"publisher","first-page":"068","DOI":"10.21926\/obm.neurobiol.2003068","volume":"4","author":"EA Armour","year":"2020","unstructured":"Armour EA, Curcio AM, Fryer RH. Neonatal hypoxic ischemic encephalopathy: an updated preclinical and clinical review. OBM Neurobiol. 2020;4(3):068.","journal-title":"OBM Neurobiol"},{"key":"8104_CR193","doi-asserted-by":"crossref","unstructured":"Sosunov S, Bhutada A, Niatsetskaya Z, Starkov A, Ten V. Mitochondrial calcium buffering depends upon temperature and is associated with hypothermic neuroprotection against hypoxia-ischemia injury. PLoS One. 2022;17(8):e0273677.","DOI":"10.1371\/journal.pone.0273677"},{"key":"8104_CR194","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3389\/fphys.2015.00083","volume":"6","author":"S Javadov","year":"2015","unstructured":"Javadov S. The calcium-ROS-pH triangle and mitochondrial permeability transition: challenges to mimic cardiac ischemia-reperfusion. Front Physiol. 2015;6:83.","journal-title":"Front. Physiol"},{"key":"8104_CR195","doi-asserted-by":"publisher","first-page":"88","DOI":"10.3389\/fnmol.2019.00088","volume":"12","author":"X Qin","year":"2019","unstructured":"Qin X, Cheng J, Zhong Y, Mahgoub OK, Akter F, Fan Y, et al. Mechanism and treatment related to oxidative stress in neonatal hypoxic-ischemic encephalopathy. Front Mol Neurosci. 2019;12:88.","journal-title":"Front Mol Neurosci"},{"key":"8104_CR196","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.freeradbiomed.2025.01.031","volume":"229","author":"R She","year":"2025","unstructured":"She R, Tian H, Sun F, Ge J, Mei Z. Naotaifang formula regulates Drp1-induced remodeling of mitochondrial dynamics following cerebral ischemia-reperfusion injury. Free Radical Biol Med. 2025;229:139\u201353.","journal-title":"Free Radical Biol Med"},{"key":"8104_CR197","doi-asserted-by":"crossref","unstructured":"Nair S, Leverin AL, Rocha-Ferreira E, Sobotka KS, Thornton C, Mallard C, et al. Induction of mitochondrial fragmentation and mitophagy after neonatal hypoxia-ischemia. Cells. 2022;11(7).","DOI":"10.3390\/cells11071193"},{"issue":"5","key":"8104_CR198","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/s41419-021-03752-2","volume":"12","author":"AR Anzell","year":"2021","unstructured":"Anzell AR, Fogo GM, Gurm Z, Raghunayakula S, Wider JM, Maheras KJ, et al. Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia\/reperfusion injury in primary neurons. Cell Death Dis. 2021;12(5):475.","journal-title":"Cell Death Dis"},{"issue":"1","key":"8104_CR199","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1186\/s12974-021-02334-5","volume":"18","author":"L Zhang","year":"2021","unstructured":"Zhang L, Dai L, Li D. Mitophagy in neurological disorders. J Neuroinflammation. 2021;18(1):297.","journal-title":"J Neuroinflammation"},{"issue":"4","key":"8104_CR200","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1242\/jcs.171017","volume":"130","author":"KH Flippo","year":"2017","unstructured":"Flippo KH, Strack S. Mitochondrial dynamics in neuronal injury, development and plasticity. J Cell Sci. 2017;130(4):671\u201381.","journal-title":"J Cell Sci"},{"key":"8104_CR201","doi-asserted-by":"publisher","first-page":"1014251","DOI":"10.3389\/fnmol.2022.1014251","volume":"15","author":"Q Wang","year":"2022","unstructured":"Wang Q, Xue H, Yue Y, Hao S, Huang SH, Zhang Z. Role of mitophagy in the neurodegenerative diseases and its pharmacological advances: a review. Front Mol Neurosci. 2022;15:1014251.","journal-title":"Front Mol Neurosci"},{"key":"8104_CR202","doi-asserted-by":"publisher","first-page":"157580","DOI":"10.1016\/j.phymed.2025.157580","volume":"149","author":"Y Liu","year":"2025","unstructured":"Liu Y, Shang H, Zhang L, Fu R, Li Y, Wang Z, et al. Timosaponin B-II attenuates cerebral ischemia injury by enhancing Parkin-mediated mitophagy. Phytomed: Int J Phytotherapy Phytopharmacology. 2025;149:157580.","journal-title":"Phytomed: Int J Phytotherapy Phytopharmacology"},{"issue":"8","key":"8104_CR203","doi-asserted-by":"publisher","first-page":"4273","DOI":"10.1007\/s12035-023-03344-5","volume":"60","author":"C Lin","year":"2023","unstructured":"Lin C, Li L, Xu Q, Xu S, Tang C. Yap1-Usp14 axis inhibits neuronal mitophagy during neonatal hypoxia-ischemia encephalopathy by regulation of Beclin-1 Ubiquitination in mouse. Mol Neurobiol. 2023;60(8):4273\u201387.","journal-title":"Mol Neurobiol"},{"key":"8104_CR204","doi-asserted-by":"publisher","first-page":"1592737","DOI":"10.3389\/fimmu.2025.1592737","volume":"16","author":"L Song","year":"2025","unstructured":"Song L, Shen H, Hong F, Zhang W, Lu H. ROR\u03b1-activated mitophagy attenuating hypoxic-ischemic encephalopathy via suppression of microglial cGAS-STING axis. Front Immunol. 2025;16:1592737.","journal-title":"Front Immunol"},{"issue":"8","key":"8104_CR205","doi-asserted-by":"publisher","first-page":"152128","DOI":"10.1016\/j.semperi.2025.152128","volume":"49","author":"H Sabir","year":"2025","unstructured":"Sabir H. Neuroprotective therapies for neonatal hypoxic-ischemic brain injury - a contemporary update. Semin Perinatol. 2025;49(8):152128.","journal-title":"Semin Perinatol"},{"key":"8104_CR206","doi-asserted-by":"publisher","first-page":"113853","DOI":"10.1016\/j.jpeds.2023.113853","volume":"266","author":"R Rao","year":"2024","unstructured":"Rao R, Comstock BA, Wu TW, Mietzsch U, Mayock DE, Gonzalez FF, et al. Time to reaching target cooling temperature and 2-year outcomes in infants with hypoxic-ischemic encephalopathy. J Pediatr. 2024;266:113853.","journal-title":"J Pediatr"},{"issue":"6","key":"8104_CR207","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1177\/0271678X15607881","volume":"36","author":"JL Wisnowski","year":"2016","unstructured":"Wisnowski JL, Wu TW, Reitman AJ, McLean C, Friedlich P, Vanderbilt D, et al. The effects of therapeutic hypothermia on cerebral metabolism in neonates with hypoxic-ischemic encephalopathy: an in vivo 1H-MR spectroscopy study. J Cereb Blood Flow Metab. 2016;36(6):1075\u201386.","journal-title":"J Cereb Blood Flow Metab"},{"issue":"1","key":"8104_CR208","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.clp.2013.10.005","volume":"41","author":"PP Drury","year":"2014","unstructured":"Drury PP, Gunn ER, Bennet L, Gunn AJ. Mechanisms of hypothermic neuroprotection. Clin Perinatol. 2014;41(1):161\u201375.","journal-title":"Clin Perinatol"},{"key":"8104_CR209","doi-asserted-by":"crossref","unstructured":"Montaldo P, Lally PJ, Oliveira V, Swamy R, Mendoza J, Atreja G, et al. Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non-randomised cohort study. Arch Dis Child Fetal Neonatal Ed. 2019;104(5):F515\u2013f520.","DOI":"10.1136\/archdischild-2018-316040"},{"issue":"22","key":"8104_CR210","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1056\/NEJMoa1112066","volume":"366","author":"S Shankaran","year":"2012","unstructured":"Shankaran S, Pappas A, McDonald SA, Vohr BR, Hintz SR, Yolton K, et al. Childhood outcomes after hypothermia for neonatal encephalopathy. N Engl J Med. 2012;366(22):2085\u201392.","journal-title":"N Engl J Med"},{"key":"8104_CR211","doi-asserted-by":"crossref","unstructured":"Cainelli E, Vedovelli L, Mastretta E, Gregori D, Suppiej A, Bisiacchi PS. Long-term outcomes after neonatal hypoxic-ischemic encephalopathy in the Era of therapeutic hypothermia: a Longitudinal, Prospective, Multicenter case-control study in Children without overt brain damage. Children (Basel). 2021;8(11).","DOI":"10.3390\/children8111076"},{"issue":"3","key":"8104_CR212","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.clp.2024.04.008","volume":"51","author":"SL Huntingford","year":"2024","unstructured":"Huntingford SL, Boyd SM, McIntyre SJ, Goldsmith SC, Hunt RW, Badawi N. Long-term outcomes following hypoxic ischemic encephalopathy. Clin Perinatol. 2024;51(3):683\u2013709.","journal-title":"Clin Perinatol"},{"issue":"6","key":"8104_CR213","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1055\/s-0042-1755235","volume":"53","author":"KA Pedroza-Garc\u00eda","year":"2022","unstructured":"Pedroza-Garc\u00eda KA, Calder\u00f3n-Vallejo D, Quintanar JL. Neonatal hypoxic-ischemic encephalopathy: perspectives of Neuroprotective and neuroregenerative treatments. Neuropediatrics. 2022;53(6):402\u201317.","journal-title":"Neuropediatrics"},{"issue":"8","key":"8104_CR214","first-page":"2034","volume":"3","author":"S Kushwah","year":"2017","unstructured":"Kushwah S, Kumar A, Basu S, Krishnamurthy S, Kumar A. Comparison of cerebrospinal fluid cytochrome-c and caspase-9 as biomarkers for newborns with hypoxic ischemic encephalopathy with non-asphyxiated babies and followup of these biomarkers after day 7. Int J ResearchMed Sci. 2017;3(8):2034\u201340.","journal-title":"Int J ResearchMed Sci"},{"issue":"6","key":"8104_CR215","first-page":"4517","volume":"17","author":"C Deng","year":"2019","unstructured":"Deng C, Li J, Li L, Sun F, Xie J. Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice. Exp Ther Med. 2019;17(6):4517\u201321.","journal-title":"Exp Ther Med"},{"key":"8104_CR216","doi-asserted-by":"crossref","unstructured":"Lear BA, McDouall AJ, Lear OJ, Dhillon SK, Lear CA, Northington FJ, et al. The potential clinical relevance of necrosis-necroptosis pathways for hypoxic-ischaemic encephalopathy. Cells. 2025;14(24).","DOI":"10.3390\/cells14241984"},{"key":"8104_CR217","doi-asserted-by":"crossref","unstructured":"Li Q, Yang L, Wang K, Chen Z, Liu H, Yang X, et al. Oxidized mitochondrial DNA activates the cGAS-STING pathway in the neuronal intrinsic immune system after brain ischemia-reperfusion injury. Neurotherapeutics: J Am Soc Exp NeuroTherapeutics. 2024;21(4):e00368.","DOI":"10.1016\/j.neurot.2024.e00368"},{"issue":"8","key":"8104_CR218","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.21037\/tp-24-148","volume":"13","author":"H Shen","year":"2024","unstructured":"Shen H, Lu H, Mao L, Song L. Inhibition of cGAS attenuates neonatal hypoxic-ischemic encephalopathy via regulating microglia polarization and pyroptosis. Transl Pediatr. 2024;13(8):1378\u201394.","journal-title":"Transl Pediatr"},{"issue":"1","key":"8104_CR219","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13024-025-00815-2","volume":"20","author":"S Quan","year":"2025","unstructured":"Quan S, Fu X, Cai H, Ren Z, Xu Y, Jia L. The neuroimmune nexus: unraveling the role of the mtDNA-cGAS-STING signal pathway in Alzheimer\u2019s disease. Mol Neurodegener. 2025;20(1):25.","journal-title":"Mol Neurodegener"},{"issue":"7973","key":"8104_CR220","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1038\/s41586-023-06373-1","volume":"620","author":"MF Gulen","year":"2023","unstructured":"Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Gl\u00fcck S, et al. cGAS-STING drives ageing-related inflammation and neurodegeneration. Nature. 2023;620(7973):374\u201380.","journal-title":"Nature"},{"key":"8104_CR221","doi-asserted-by":"crossref","unstructured":"Zhang X, Zeng W, Zhang Y, Yu Q, Zeng M, Gan J, et al. Focus on the role of mitochondria in NLRP3 inflammasome activation: a prospective target for the treatment of ischemic stroke (review). Int J Mol Med. 2022;49(6).","DOI":"10.3892\/ijmm.2022.5130"},{"key":"8104_CR222","doi-asserted-by":"crossref","unstructured":"Falsaperla R, Lombardo F, Filosco F, Romano C, Saporito MAN, Puglisi F, et al. Oxidative stress in preterm infants: overview of Current Evidence and future prospects. Pharmaceuticals (Basel). 2020;13(7).","DOI":"10.3390\/ph13070145"},{"key":"8104_CR223","doi-asserted-by":"publisher","first-page":"793862","DOI":"10.3389\/fnut.2021.793862","volume":"8","author":"MD Ord\u00f3\u00f1ez-D\u00edaz","year":"2021","unstructured":"Ord\u00f3\u00f1ez-D\u00edaz MD, Gil-Campos M, Flores-Rojas K, Mu\u00f1oz-Villanueva MC, Mesa MD, de la Torre-Aguilar MJ, et al. Impaired antioxidant defence status is associated with metabolic-inflammatory risk factors in preterm Children with extrauterine growth restriction: the BIORICA cohort study. Front Nutr. 2021;8:793862.","journal-title":"Front Nutr"},{"issue":"1","key":"8104_CR224","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/s13052-025-02079-4","volume":"51","author":"Q Jiang","year":"2025","unstructured":"Jiang Q, Wen J, Ding Y, Cui H. From vulnerability to resilience: unraveling the role of oxidative stress in preterm brain injury. Ital J Pediatr. 2025;51(1):232.","journal-title":"Ital J Pediatr"},{"key":"8104_CR225","doi-asserted-by":"crossref","unstructured":"Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z. The Neuroprotective mechanisms of PPAR-\u03b3: inhibition of microglia-mediated neuroinflammation and oxidative stress in a neonatal mouse model of hypoxic-ischemic white matter injury. CNS Neurosci Ther. 2024;30(11):e70081.","DOI":"10.1111\/cns.70081"},{"key":"8104_CR226","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3389\/fphys.2019.00417","volume":"10","author":"S Pregnolato","year":"2019","unstructured":"Pregnolato S, Chakkarapani E, Isles AR, Luyt K. Glutamate Transport and Preterm Brain Injury. Front. Physiol. 2019;10:417.","journal-title":"Front. Physiol"},{"key":"8104_CR227","doi-asserted-by":"publisher","first-page":"618052","DOI":"10.3389\/fped.2021.618052","volume":"9","author":"JC Shaw","year":"2021","unstructured":"Shaw JC, Crombie GK, Palliser HK, Hirst JJ. Impaired oligodendrocyte development following preterm birth: promoting GABAergic action to improve outcomes. Front. Pediatr. 2021;9:618052.","journal-title":"Front. Pediatr"},{"issue":"13","key":"8104_CR228","doi-asserted-by":"publisher","first-page":"2042","DOI":"10.1016\/j.neuron.2025.03.024","volume":"113","author":"P Kratimenos","year":"2025","unstructured":"Kratimenos P, Sanidas G, Simonti G, Byrd C, Gallo V. The shifting landscape of the preterm brain. Neuron. 2025;113(13):2042\u201364.","journal-title":"Neuron"},{"issue":"5","key":"8104_CR229","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1159\/000536509","volume":"46","author":"T Zhao","year":"2024","unstructured":"Zhao T, Chang X, Biswas SK, Balsbaugh JL, Liddle J, Chen MH, et al. Pain\/Stress, mitochondrial dysfunction, and neurodevelopment in preterm infants. Dev Neurosci. 2024;46(5):341\u201352.","journal-title":"Dev Neurosci"},{"issue":"4","key":"8104_CR230","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1002\/glia.24648","volume":"73","author":"AL Soung","year":"2025","unstructured":"Soung AL, Kyauk RV, Pandey S, Shen YA, Reichelt M, Lin H, et al. Modulation of OPC mitochondrial function by inhibiting USP30 promotes their differentiation. Glia. 2025;73(4):773\u201387.","journal-title":"Glia"},{"issue":"11","key":"8104_CR231","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.1002\/glia.24235","volume":"70","author":"J Steudler","year":"2022","unstructured":"Steudler J, Ecott T, Ivan DC, Bouillet E, Walthert S, Berve K, et al. Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes. Glia. 2022;70(11):2045\u201361.","journal-title":"Glia"},{"issue":"3","key":"8104_CR232","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1007\/s12264-024-01292-1","volume":"41","author":"H Chen","year":"2025","unstructured":"Chen H, Yang G, Xu DE, Du YT, Zhu C, Hu H, et al. Autophagy in oligodendrocyte lineage cells controls oligodendrocyte Numbers and myelin integrity in an age-dependent manner. Neurosci Bull. 2025;41(3):374\u201390.","journal-title":"Neurosci Bull"},{"key":"8104_CR233","doi-asserted-by":"publisher","first-page":"764486","DOI":"10.3389\/fncel.2021.764486","volume":"15","author":"M Motavaf","year":"2021","unstructured":"Motavaf M, Piao X. Oligodendrocyte development and implication in perinatal white matter injury. Front Cell Neurosci. 2021;15:764486.","journal-title":"Front Cell Neurosci"},{"issue":"3","key":"8104_CR234","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1159\/000499346","volume":"116","author":"M Martinez-Biarge","year":"2019","unstructured":"Martinez-Biarge M, Groenendaal F, Kersbergen KJ, Benders M, Foti F, van Haastert IC, et al. Neurodevelopmental outcomes in preterm infants with white matter injury using a New MRI classification. Neonatology. 2019;116(3):227\u201335.","journal-title":"Neonatology"},{"key":"8104_CR235","doi-asserted-by":"crossref","unstructured":"Cayam-Rand D, Guo T, Grunau RE, Benavente-Fern\u00e1ndez I, Synnes A, Chau V, et al. Predicting developmental outcomes in preterm infants: a simple white matter injury imaging rule. Neurology. 2019;93(13):e1231\u2013e 1240.","DOI":"10.1212\/WNL.0000000000008172"},{"key":"8104_CR236","doi-asserted-by":"crossref","unstructured":"Silveira RC, Valentini NC, O\u2019Shea TM, Mendes EW, Froes G, Cauduro L, et al. Parent-guided developmental intervention for infants with very low birth weight: a randomized clinical trial. JAMA Netw Open. 2024;7(7):e2421896.","DOI":"10.1001\/jamanetworkopen.2024.21896"},{"key":"8104_CR237","doi-asserted-by":"publisher","first-page":"674221","DOI":"10.3389\/fped.2021.674221","volume":"9","author":"L Jansen","year":"2021","unstructured":"Jansen L, Peeters-Scholte C, van den Berg-Huysmans AA, van Klink JMM, Rijken M, van Egmond-van Dam JC, et al. Longitudinal follow-up of Children born preterm: neurodevelopment from 2 to 10 years of age. Front Pediatr. 2021;9:674221.","journal-title":"Front. Pediatr"},{"key":"8104_CR238","doi-asserted-by":"crossref","unstructured":"Tegegne KT, Wudu TK, Abebe MT, Tegegne ET, Tessema MK. Preterm birth as a risk factor for cerebral palsy in Children: a systematic review and meta-analysis. Neurol Res Int. 2025;3922172.","DOI":"10.1155\/nri\/3922172"},{"key":"8104_CR239","doi-asserted-by":"crossref","unstructured":"Hee Chung E, Chou J, Brown KA. Neurodevelopmental outcomes of preterm infants: a recent literature review. Transl Pediatr. 2020;9(Suppl 1):S3\u2013s8.","DOI":"10.21037\/tp.2019.09.10"},{"key":"8104_CR240","doi-asserted-by":"crossref","unstructured":"Puia-Dumitrescu M, Wood TR, Comstock BA, Law JB, German K, Perez KM, et al. Dexamethasone, prednisolone, and methylprednisolone use and 2-year neurodevelopmental outcomes in extremely preterm infants. JAMA Netw Open. 2022;5(3):e221947.","DOI":"10.1001\/jamanetworkopen.2022.1947"},{"key":"8104_CR241","doi-asserted-by":"crossref","unstructured":"H\u00e4usler S, Robertson NJ, Golhen K, van den Anker J, Tucker K, Felder TK. Melatonin as a therapy for preterm brain injury: what is the Evidence? Antioxid (Basel). 2023;12(8).","DOI":"10.3390\/antiox12081630"},{"key":"8104_CR242","doi-asserted-by":"publisher","first-page":"1594133","DOI":"10.3389\/fimmu.2025.1594133","volume":"16","author":"KQ Chen","year":"2025","unstructured":"Chen KQ, Tang WR, Liu X. Research and progress of cGAS\/STING\/NLRP3 signaling pathway: a mini review. Front Immunol. 2025;16:1594133.","journal-title":"Front Immunol"},{"issue":"9","key":"8104_CR243","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1161\/01.RES.86.9.960","volume":"86","author":"SW Ballinger","year":"2000","unstructured":"Ballinger SW, Patterson C, Yan CN, Doan R, Burow DL, Young CG, et al. Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells. Circ Res. 2000;86(9):960\u201366.","journal-title":"Circ Res"},{"issue":"1","key":"8104_CR244","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1186\/s13054-024-05069-w","volume":"28","author":"D Hu","year":"2024","unstructured":"Hu D, Sheeja Prabhakaran H, Zhang YY, Luo G, He W, Liou YC. Mitochondrial dysfunction in sepsis: mechanisms and therapeutic perspectives. Crit Care. 2024;28(1):292.","journal-title":"Crit Care"},{"issue":"6","key":"8104_CR245","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.1007\/s10753-021-01501-3","volume":"44","author":"Q Gao","year":"2021","unstructured":"Gao Q, Hernandes MS. Sepsis-associated encephalopathy and blood-brain barrier dysfunction. Inflammation. 2021;44(6):2143\u201350.","journal-title":"Inflammation"},{"issue":"1","key":"8104_CR246","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s12987-025-00699-w","volume":"22","author":"Y Shao","year":"2025","unstructured":"Shao Y, Mai L, Qiao R, Liang Y, Jiao Y, Homburg J, et al. Song L: endothelial mitochondria in the blood-brain barrier. Fluids Barriers CNS. 2025;22(1):88.","journal-title":"Fluids Barriers CNS"},{"issue":"1","key":"8104_CR247","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/s12974-025-03507-2","volume":"22","author":"QQ Zeng","year":"2025","unstructured":"Zeng QQ, Qi Y, Yu H, Xu Y, Chen JX, Zheng YW, et al. Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy. J Neuroinflammation. 2025;22(1):176.","journal-title":"J Neuroinflammation"},{"issue":"1","key":"8104_CR248","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s10565-025-10051-5","volume":"41","author":"T Yu","year":"2025","unstructured":"Yu T, Fleishman JS, Wang H, Liu X, Huo L. cGAS-STING targeting offers novel therapeutic regimen in sepsis-associated organ dysfunction. Cell Biol Toxicol. 2025;41(1):113.","journal-title":"Cell Biol Toxicol"},{"issue":"1","key":"8104_CR249","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1186\/s12967-025-06635-8","volume":"23","author":"D Xiao","year":"2025","unstructured":"Xiao D, Wang X, Liang W, Yang Y, Du Y, Liu C, et al. Convergence of sepsis-associated encephalopathy pathogenesis onto microglia. J Transl Med. 2025;23(1):622.","journal-title":"J Transl Med"},{"issue":"1","key":"8104_CR250","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s10020-023-00621-w","volume":"29","author":"JS Dumbuya","year":"2023","unstructured":"Dumbuya JS, Li S, Liang L, Zeng Q. Paediatric sepsis-associated encephalopathy (SAE): a comprehensive review. Mol Med. 2023;29(1):27.","journal-title":"Mol Med"},{"issue":"1","key":"8104_CR251","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.cmi.2023.04.017","volume":"30","author":"R Thomas","year":"2024","unstructured":"Thomas R, Bijlsma MW, Gon\u00e7alves BP, Nakwa FL, Velaphi S, Heath PT. Long-term impact of serious neonatal bacterial infections on neurodevelopment. Clin Microbiol Infect. 2024;30(1):28\u201337.","journal-title":"Clin Microbiol Infect"},{"key":"8104_CR252","doi-asserted-by":"crossref","unstructured":"McAdams RM, Juul SE. The role of cytokines and inflammatory cells in perinatal brain injury. Neurol Res Int. 2012;561494.","DOI":"10.1155\/2012\/561494"},{"key":"8104_CR253","doi-asserted-by":"publisher","first-page":"3437","DOI":"10.2147\/IDR.S368772","volume":"15","author":"S Chen","year":"2022","unstructured":"Chen S, Kuang M, Qu Y, Huang S, Gong B, Lin S, et al. Expression of Serum cytokines profile in neonatal sepsis. Infect Drug Resist. 2022;15:3437\u201345.","journal-title":"Infect Drug Resist"},{"key":"8104_CR254","doi-asserted-by":"crossref","unstructured":"Cai S, Thompson DK, Anderson PJ, Yang JY. Short- and long-term neurodevelopmental outcomes of Very preterm infants with neonatal sepsis: a systematic review and meta-analysis. Children (Basel). 2019;6(12).","DOI":"10.3390\/children6120131"},{"issue":"6","key":"8104_CR255","doi-asserted-by":"publisher","first-page":"2026","DOI":"10.1038\/s41390-023-02742-8","volume":"94","author":"\u015e Kurul","year":"2023","unstructured":"Kurul \u015e, Beckers FLM, Vermeulen MJ, Suurland J, Hasbek JE, Ramakers CRB, et al. Inflammation, sepsis severity and neurodevelopmental outcomes of late-onset sepsis in preterm neonates. Pediatr Res. 2023;94(6):2026\u201332.","journal-title":"Pediatr Res"},{"key":"8104_CR256","doi-asserted-by":"crossref","unstructured":"Bhat V, Bhandari V. Does neonatal sepsis independently increase neurodevelopmental impairment? Children (Basel). 2022;9(4).","DOI":"10.3390\/children9040568"},{"key":"8104_CR257","doi-asserted-by":"crossref","unstructured":"Mohamed Ahmed Hamid SM, Ibrahim Shaban KS, Abdulhamid Abdulaziz SB, Ahmed Mohamed SYM, Abdo Osman SK. Abd Alnour Suliman ET: the impact of neonatal sepsis on long-term neurodevelopment: a systematic review of cognitive and sensory outcomes. Cureus. 2025;17(8):e90176.","DOI":"10.7759\/cureus.90176"},{"issue":"11","key":"8104_CR258","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1007\/s12519-024-00836-9","volume":"20","author":"CC Babbo","year":"2024","unstructured":"Babbo CC, Mellet J, van Rensburg J, Pillay S, Horn AR, Nakwa FL, et al. Neonatal encephalopathy due to suspected hypoxic ischemic encephalopathy: pathophysiology, current, and emerging treatments. World J Pediatr. 2024;20(11):1105\u201314.","journal-title":"World J Pediatr"},{"issue":"3","key":"8104_CR259","doi-asserted-by":"publisher","first-page":"035001","DOI":"10.1117\/1.NPh.9.3.035001","volume":"9","author":"D Milej","year":"2022","unstructured":"Milej D, Rajaram A, Suwalski M, Morrison LB, Shoemaker LN, St Lawrence K. Assessing the relationship between the cerebral metabolic rate of oxygen and the oxidation state of cytochrome-c-oxidase. Neurophotonics. 2022;9(3):035001.","journal-title":"Neurophotonics"},{"issue":"1","key":"8104_CR260","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/S1095-6433(01)00540-2","volume":"132","author":"T Zaitseva","year":"2002","unstructured":"Zaitseva T, Shen J, Schears G, Creed J, Wilson DF, Pastuszko A. Effect of catecholamines on activity of Na(+), K(+)-ATPase in neonatal piglet brain during posthypoxic reoxygenation. Comp Biochem Physiol Mol Integr Physiol. 2002;132(1):139\u201345.","journal-title":"Comp Biochem Physiol Mol Integr Physiol"},{"key":"8104_CR261","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3389\/fncel.2020.00051","volume":"14","author":"D Belov Kirdajova","year":"2020","unstructured":"Belov Kirdajova D, Kriska J, Tureckova J, Anderova M. Ischemia-triggered glutamate excitotoxicity from the Perspective of glial cells. Front Cell Neurosci. 2020;14:51.","journal-title":"Front Cell Neurosci"},{"key":"8104_CR262","doi-asserted-by":"crossref","unstructured":"Wu TW, Tamrazi B, Hsu KH, Ho E, Reitman AJ, Borzage M, et al. Cereb Lactate Concentration Neonatal Hypoxic-Ischemic Encephalopathy: Relation To Time, Characteristic Inj, Serum Lactate Concentration. Front Neurol. 2018;9:293.","DOI":"10.3389\/fneur.2018.00293"},{"issue":"1","key":"8104_CR263","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1038\/s41598-022-27034-9","volume":"13","author":"EJ Teo","year":"2023","unstructured":"Teo EJ, Chand KK, Miller SM, Wixey JA, Colditz PB, Bjorkman ST. Early evolution of glial morphology and inflammatory cytokines following hypoxic-ischemic injury in the newborn piglet brain. Sci Rep. 2023;13(1):282.","journal-title":"Sci Rep"},{"issue":"12","key":"8104_CR264","doi-asserted-by":"publisher","first-page":"608","DOI":"10.3345\/cep.2021.00164","volume":"64","author":"BL Lee","year":"2021","unstructured":"Lee BL, Glass HC. Cognitive outcomes in late childhood and adolescence of neonatal hypoxic-ischemic encephalopathy. Clin Exp Pediatr. 2021;64(12):608\u201318.","journal-title":"Clin Exp Pediatr"},{"issue":"3","key":"8104_CR265","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/s41390-024-03255-8","volume":"96","author":"S Kota","year":"2024","unstructured":"Kota S, Kang S, Liu YL, Liu H, Montazeri S, Vanhatalo S, et al. Prognostic value of quantitative EEG in early hours of life for neonatal encephalopathy and neurodevelopmental outcomes. Pediatr Res. 2024;96(3):685\u201394.","journal-title":"Pediatr Res"},{"issue":"1","key":"8104_CR266","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1001\/jamapediatrics.2019.4011","volume":"174","author":"M Finder","year":"2020","unstructured":"Finder M, Boylan GB, Twomey D, Ahearne C, Murray DM, Hallberg B. Two-year neurodevelopmental outcomes after mild hypoxic ischemic encephalopathy in the Era of therapeutic hypothermia. JAMA Pediatr. 2020;174(1):48\u201355.","journal-title":"JAMA Pediatr"},{"key":"8104_CR267","doi-asserted-by":"crossref","unstructured":"Montaldo P, Cirillo M, Burgod C, Caredda E, Ascione S, Carpentieri M, et al. Whole-body hypothermia vs targeted normothermia for neonates with mild encephalopathy: a Multicenter pilot randomized clinical trial. JAMA Netw Open. 2024;7(5):e249119.","DOI":"10.1001\/jamanetworkopen.2024.9119"},{"key":"8104_CR268","doi-asserted-by":"publisher","first-page":"100945","DOI":"10.1016\/j.resplu.2025.100945","volume":"23","author":"C Endisch","year":"2025","unstructured":"Endisch C, Millard K, Preu\u00df S, Stenzel W, Nee J, Storm C, et al. Duration of resuscitation, regain of consciousness and histopathological severity of hypoxic-ischemic encephalopathy after cardiac arrest. Resusc Plus. 2025;23:100945.","journal-title":"Resusc Plus"},{"key":"8104_CR269","doi-asserted-by":"crossref","unstructured":"Jithoo A, Penny TR, Pham Y, Sutherland AE, Smith MJ, Petraki M, et al. The temporal relationship between blood-brain barrier integrity and microglial response following neonatal hypoxia ischemia. Cells. 2024;13(8).","DOI":"10.3390\/cells13080660"},{"key":"8104_CR270","doi-asserted-by":"crossref","unstructured":"Pham L, Arroum T, Morse PT, Bell J, Malek MH, Sanderson TH, et al. Inhibitory infrared light attenuates mitochondrial hyperactivity and accelerates Restoration of mitochondrial homeostasis in an oxygen-glucose Deprivation\/Reoxygenation model. Antioxid (Basel). 2025;14(9).","DOI":"10.3390\/antiox14091119"},{"issue":"1","key":"8104_CR271","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s12975-013-0322-x","volume":"5","author":"C Uria-Avellanal","year":"2014","unstructured":"Uria-Avellanal C, Robertson NJ. Na+\/H+ exchangers and intracellular pH in perinatal brain injury. Transl Stroke Res. 2014;5(1):79\u201398.","journal-title":"Transl Stroke Res"},{"key":"8104_CR272","doi-asserted-by":"publisher","first-page":"104821","DOI":"10.1016\/j.mvr.2025.104821","volume":"160","author":"S Xiang","year":"2025","unstructured":"Xiang S, Tang X. Interfering with AQP1 alleviates ferroptosis, improves mitochondrial function and energy metabolic disorder in hypoxia\/reoxygenation-induced H9c2 cardiomyocytes via Wnt\/\u03b2-catenin pathway. Microvasc Res. 2025;160:104821.","journal-title":"Microvasc Res"},{"key":"8104_CR273","doi-asserted-by":"publisher","first-page":"110309","DOI":"10.1016\/j.resuscitation.2024.110309","volume":"202","author":"N Bruns","year":"2024","unstructured":"Bruns N, Feddahi N, Hojeij R, Rossi R, Dohna-Schwake C, Stein A, et al. Short-term outcomes of asphyxiated neonates depending on requirement for transfer in the first 24 h of life. Resuscitation. 2024;202:110309.","journal-title":"Resuscitation"},{"issue":"6","key":"8104_CR274","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1038\/s41390-018-0174-x","volume":"84","author":"LF Chalak","year":"2018","unstructured":"Chalak LF, Nguyen KA, Prempunpong C, Heyne R, Thayyil S, Shankaran S, et al. Prospective research in infants with mild encephalopathy identified in the first six hours of life: neurodevelopmental outcomes at 18\u201322 months. Pediatr Res. 2018;84(6):861\u201368.","journal-title":"Pediatr Res"},{"issue":"1","key":"8104_CR275","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1097\/AOG.0000000000005392","volume":"143","author":"T Arnautovic","year":"2024","unstructured":"Arnautovic T, Sinha S, Laptook AR. Neonatal hypoxic-ischemic encephalopathy and hypothermia treatment. Obstet Gynecol. 2024;143(1):67\u201381.","journal-title":"Obstet Gynecol"},{"issue":"13","key":"8104_CR276","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1055\/s-0038-1676973","volume":"36","author":"R Rao","year":"2019","unstructured":"Rao R, Trivedi S, Distler A, Liao S, Vesoulis Z, Smyser C, et al. Neurodevelopmental outcomes in neonates with mild hypoxic ischemic encephalopathy Treated with therapeutic hypothermia. Am J Perinatol. 2019;36(13):1337\u201343.","journal-title":"Am J Perinatol"},{"issue":"1158","key":"8104_CR277","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1093\/bjr\/tqae048","volume":"97","author":"SC Hung","year":"2024","unstructured":"Hung SC, Tu YF, Hunter SE, Guimaraes C. MRI predictors of long-term outcomes of neonatal hypoxic ischaemic encephalopathy: a primer for radiologists. The Br J Radiol. 2024;97(1158):1067\u201377.","journal-title":"The Br J Radiol"},{"key":"8104_CR278","doi-asserted-by":"crossref","unstructured":"Variane GFT, Dahlen A, Pietrobom RFR, Rodrigues DP, Magalh\u00e3es M, Mimica MJ, et al. Remote monitoring for seizures during therapeutic hypothermia in neonates with hypoxic-ischemic encephalopathy. JAMA Netw Open Open. 2023;6(11):e2343429\u20132343429.","DOI":"10.1001\/jamanetworkopen.2023.43429"},{"key":"8104_CR279","doi-asserted-by":"publisher","first-page":"1280489","DOI":"10.3389\/fped.2024.1280489","volume":"12","author":"L Fan","year":"2024","unstructured":"Fan L, Feng L, Gan J, Luo R, Qu H, Chen X. Clinical characteristics of cystic encephalomalacia in children. Front. Pediatr. 2024;12:1280489.","journal-title":"Front. Pediatr"},{"issue":"1","key":"8104_CR280","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1038\/s41420-023-01663-z","volume":"9","author":"C Zhao","year":"2023","unstructured":"Zhao C, Liang F, Ye M, Wu S, Qin Y, Zhao L, et al. GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia\/reperfusion. Cell Death Discov. 2023;9(1):368.","journal-title":"Cell Death Discov"},{"key":"8104_CR281","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.molimm.2017.04.007","volume":"87","author":"ZS Wang","year":"2017","unstructured":"Wang ZS, Liu YL, Mi N, Duan DY. Intracellular DNA sensing pathway of cGAS-cGAMP is decreased in human newborns and young children. Mol Immunol. 2017;87:76\u201385.","journal-title":"Mol Immunol"},{"issue":"1","key":"8104_CR282","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/apa.14821","volume":"109","author":"M Schreglmann","year":"2020","unstructured":"Schreglmann M, Ground A, Vollmer B, Johnson MJ. Systematic review: long-term cognitive and behavioural outcomes of neonatal hypoxic-ischaemic encephalopathy in children without cerebral palsy. Acta Paediatr. 2020;109(1):20\u201330.","journal-title":"Acta Paediatr"},{"key":"8104_CR283","doi-asserted-by":"publisher","first-page":"1611345","DOI":"10.3389\/fped.2025.1611345","volume":"13","author":"J Shu","year":"2025","unstructured":"Shu J, Liu L, Yuan M, Ma M, Yang J. Paradigm shifts in neonatal hypoxic-ischemic encephalopathy therapeutics: a four-decade bibliometric exploration of emerging therapeutic dimensions (1985-2024). Front. Pediatr. 2025;13:1611345.","journal-title":"Front. Pediatr"},{"issue":"17","key":"8104_CR284","doi-asserted-by":"publisher","first-page":"3327","DOI":"10.1093\/hmg\/ddx217","volume":"26","author":"M Khacho","year":"2017","unstructured":"Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, et al. Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis. Hum Mol Genet. 2017;26(17):3327\u201341.","journal-title":"Hum Mol Genet"},{"key":"8104_CR285","doi-asserted-by":"publisher","first-page":"1570596","DOI":"10.3389\/fncel.2025.1570596","volume":"19","author":"OA Olatona","year":"2025","unstructured":"Olatona OA, Sterben SP, Kansakar SBS, Symes AJ, Liaudanskaya V. Mitochondria: the hidden engines of traumatic brain injury-driven neurodegeneration. Front Cell Neurosci. 2025;19:1570596.","journal-title":"Front Cell Neurosci"},{"key":"8104_CR286","doi-asserted-by":"crossref","unstructured":"Shaligram R, Garud BP, Malwade S, Mane SV, Dua J, Bahal M, et al. Risk factors and predictors of outcomes in hypoxic-ischemic encephalopathy in neonates. Cureus. 2024;16(11):e73407.","DOI":"10.7759\/cureus.73407"},{"issue":"1","key":"8104_CR287","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s12974-018-1149-x","volume":"15","author":"R Gussenhoven","year":"2018","unstructured":"Gussenhoven R, Westerlaken RJJ, Ophelders D, Jobe AH, Kemp MW, Kallapur SG, et al. Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus. J Neuroinflammation. 2018;15(1):113.","journal-title":"J Neuroinflammation"},{"issue":"8","key":"8104_CR288","doi-asserted-by":"publisher","first-page":"39286","DOI":"10.31083\/JIN39286","volume":"24","author":"Y Wang","year":"2025","unstructured":"Wang Y, Yin X, Zhang X, Zhu X, Luo Y, Zhao BQ. Inhibition of cGAS reduces brain injury and facilitates neurological recovery via the STING-Mediated signaling pathway after germinal matrix hemorrhage in neonatal mice. J. Integr. Neurosci. 2025;24(8):39286.","journal-title":"J. Integr. Neurosci"},{"key":"8104_CR289","doi-asserted-by":"publisher","first-page":"1353039","DOI":"10.3389\/fimmu.2024.1353039","volume":"15","author":"J Jans","year":"2024","unstructured":"Jans J, van Dun SCJ, Gorissen R, Pieterman RFA, Voskamp TS, Schoenmakers S, et al. The monocyte-derived cytokine response in whole blood from preterm newborns against sepsis-related bacteria is similar to term newborns and adults. Front Immunol. 2024;15:1353039.","journal-title":"Front Immunol"},{"issue":"11","key":"8104_CR290","doi-asserted-by":"publisher","first-page":"7150","DOI":"10.4049\/jimmunol.0901481","volume":"183","author":"TR Kollmann","year":"2009","unstructured":"Kollmann TR, Crabtree J, Rein-Weston A, Blimkie D, Thommai F, Wang XY, et al., 3rd, Hajjar AM, et al. Neonatal innate TLR-mediated responses are distinct from those of adults. J Immunol. 2009;183(11):7150\u201360.","journal-title":"J Immunol"},{"issue":"6","key":"8104_CR291","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1073\/pnas.1911579117","volume":"117","author":"AG Stanbery","year":"2020","unstructured":"Stanbery AG, Newman ZR, Barton GM. Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-\u03b3. Proc Natl Acad Sci U S A. 2020;117(6):3074\u201382.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"8104_CR292","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/s41420-025-02458-0","volume":"11","author":"N Wang","year":"2025","unstructured":"Wang N, Wang X, Lan B, Gao Y, Cai Y. DRP1, fission and apoptosis. Cell Death Discov. 2025;11(1):150.","journal-title":"Cell Death Discov"},{"issue":"12","key":"8104_CR293","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1038\/nrd.2018.174","volume":"17","author":"MP Murphy","year":"2018","unstructured":"Murphy MP, Hartley RC. Mitochondria as a therapeutic target for common pathologies. Nat Rev Drug Discov. 2018;17(12):865\u201386.","journal-title":"Nat Rev Drug Discov"},{"key":"8104_CR294","doi-asserted-by":"crossref","unstructured":"Abrego-Guandique DM, Aguilera Rojas NM, Chiari A, Luciani F, Cione E, Cannataro R. The impact of exercise on mitochondrial biogenesis in skeletal muscle: a systematic review and meta-analysis of randomized trials. Biomol Concepts. 2025;16(1).","DOI":"10.1515\/bmc-2025-0055"},{"issue":"10","key":"8104_CR295","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1007\/s11010-022-04656-1","volume":"478","author":"MS Mohan","year":"2023","unstructured":"Mohan MS, Aswani SS, Aparna NS, Boban PT, Sudhakaran PR, Saja K. Effect of acute cold exposure on cardiac mitochondrial function: role of sirtuins. Mol Cell Biochem. 2023;478(10):2257\u201370.","journal-title":"Mol Cell Biochem"},{"key":"8104_CR296","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.neuro.2020.04.006","volume":"79","author":"U Joshi","year":"2020","unstructured":"Joshi U, Evans JE, Pearson A, Saltiel N, Cseresznye A, Darcey T, et al. Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model. Neurotoxicology. 2020;79:84\u201394.","journal-title":"Neurotoxicology"},{"key":"8104_CR297","doi-asserted-by":"crossref","unstructured":"Li W, Zhou Y, Pang N, Hu Q, Li Q, Sun Y, et al. NAD supplement alleviates intestinal barrier injury induced by ethanol via protecting epithelial mitochondrial function. Nutrients. 2022;15(1).","DOI":"10.3390\/nu15010174"},{"issue":"2","key":"8104_CR298","doi-asserted-by":"publisher","first-page":"100929","DOI":"10.1016\/j.jbc.2021.100929","volume":"297","author":"Y Huang","year":"2021","unstructured":"Huang Y, Lu J, Zhan L, Wang M, Shi R, Yuan X, et al. Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism. J Biol Chem. 2021;297(2):100929.","journal-title":"J Biol Chem"},{"issue":"1","key":"8104_CR299","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/s41591-022-02103-8","volume":"29","author":"TA Yap","year":"2023","unstructured":"Yap TA, Daver N, Mahendra M, Zhang J, Kamiya-Matsuoka C, Meric-Bernstam F, et al. Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nat Med. 2023;29(1):115\u201326.","journal-title":"Nat Med"},{"issue":"21","key":"8104_CR300","doi-asserted-by":"publisher","first-page":"7481","DOI":"10.1074\/jbc.RA120.013366","volume":"295","author":"A Tsuji","year":"2020","unstructured":"Tsuji A, Akao T, Masuya T, Murai M, Miyoshi H. IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism. J Biol Chem. 2020;295(21):7481\u201391.","journal-title":"J Biol Chem"},{"key":"8104_CR301","first-page":"101212","volume":"43","author":"A Ambrose","year":"2025","unstructured":"Ambrose A, McCabe M, Hung C, Sosova I, Seres P, Mercimek-Andrews S. Outcome of creatine supplementation therapy in phosphoglucomutase-1 deficiency associated congenital disorders of glycosylation: novel insights. Mol Genet Metab Rep. 2025;43:101212.","journal-title":"Mol Genet Metab Rep"},{"key":"8104_CR302","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.freeradbiomed.2018.06.040","volume":"124","author":"M Kim","year":"2018","unstructured":"Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, et al. Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radical Biol Med. 2018;124:517\u201324.","journal-title":"Free Radical Biol Med"},{"key":"8104_CR303","doi-asserted-by":"publisher","first-page":"4975","DOI":"10.2147\/DDDT.S484969","volume":"18","author":"L Lu","year":"2024","unstructured":"Lu L, Pang M, Chen T, Hu Y, Chen L, Tao X, et al. Protopine exerts Neuroprotective effects on neonatal hypoxic-ischemic brain damage in rats via activation of the AMPK\/PGC1\u03b1 pathway. Drug Des Devel Ther. 2024;18:4975\u201392.","journal-title":"Drug Des Devel Ther"},{"issue":"19","key":"8104_CR304","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1161\/01.CIR.0000146894.45533.C2","volume":"110","author":"MS Damian","year":"2004","unstructured":"Damian MS, Ellenberg D, Gildemeister R, Lauermann J, Simonis G, Sauter W, et al. Coenzyme Q10 combined with mild hypothermia after cardiac arrest: a preliminary study. Circulation. 2004;110(19):3011\u201316.","journal-title":"Circulation"},{"issue":"6","key":"8104_CR305","doi-asserted-by":"publisher","first-page":"110208","DOI":"10.1016\/j.jbc.2025.110208","volume":"301","author":"X Ti","year":"2025","unstructured":"Ti X, Zuo H, Zhao G, Li Y, Du M, Xu L, et al. Parkin mediates the mitochondrial dysfunction through mRpl18. J Biol Chem. 2025;301(6):110208.","journal-title":"J Biol Chem"},{"issue":"Pt B","key":"8104_CR306","doi-asserted-by":"publisher","first-page":"111210","DOI":"10.1016\/j.intimp.2023.111210","volume":"125","author":"H Zhang","year":"2023","unstructured":"Zhang H, Niu Y, Qiu L, Yang J, Sun J, Xia J. Melatonin-mediated mitophagy protects against long-term impairments after repeated neonatal sevoflurane exposures. Int Immunopharmacol. 2023;125(Pt B):111210.","journal-title":"Int Immunopharmacol"},{"issue":"1\u20134","key":"8104_CR307","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/biof.5520250117","volume":"25","author":"E Teran","year":"2005","unstructured":"Teran E, Vivero S, Racines-Orbe M, Castellanos A, Chuncha G, Enriquez G, et al. Coenzyme Q10 is increased in placenta and cord blood during preeclampsia. Biofactors. 2005;25(1\u20134):153\u201358.","journal-title":"Biofactors"},{"issue":"2","key":"8104_CR308","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1080\/10715760500404805","volume":"40","author":"JL Quiles","year":"2006","unstructured":"Quiles JL, Ochoa JJ, Ramirez-Tortosa MC, Linde J, Bompadre S, Battino M, et al. Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants. Free Radic Res. 2006;40(2):199\u2013206.","journal-title":"Free Radic Res"},{"issue":"3","key":"8104_CR309","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1159\/000079393","volume":"86","author":"G Compagnoni","year":"2004","unstructured":"Compagnoni G, Giuffr\u00e8 B, Lista G, Mosca F, Marini A. CoQ10 plasmatic levels in breast-fed infants compared to formula-fed infants. Biol Neonate. 2004;86(3):165\u201369.","journal-title":"Biol Neonate"},{"issue":"3","key":"8104_CR310","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1038\/jp.2014.186","volume":"35","author":"H Aly","year":"2015","unstructured":"Aly H, Elmahdy H, El-Dib M, Rowisha M, Awny M, El-Gohary T, et al. Melatonin use for neuroprotection in perinatal asphyxia: a randomized controlled pilot study. J Perinatol. 2015;35(3):186\u201391.","journal-title":"J Perinatol"},{"key":"8104_CR311","doi-asserted-by":"crossref","unstructured":"Pang R, Macneil A, Wadke A, Jaami Y, Marlow N, Standing JF, et al. Acute high Dose Melatonin for encephalopathy of the Newborn (ACUMEN) study: a protocol for a multicentre phase 1 safety trial of melatonin to augment therapeutic hypothermia for moderate\/severe hypoxic ischaemic encephalopathy. BMJ Open. 2025;15(8):e107083.","DOI":"10.1136\/bmjopen-2025-107083"},{"key":"8104_CR312","doi-asserted-by":"crossref","unstructured":"Fan W, Oh TG, Wang HJ, Crossley L, He M, Robbins H, et al. Estrogen-related receptors regulate innate and adaptive muscle mitochondrial energetics through cooperative and distinct actions. Proc Natl Acad Sci U S A. 2025;122(20):e2426179122.","DOI":"10.1073\/pnas.2426179122"},{"issue":"1","key":"8104_CR313","doi-asserted-by":"publisher","first-page":"26216","DOI":"10.1038\/s41598-024-76825-9","volume":"14","author":"SK Wu","year":"2024","unstructured":"Wu SK, Wang L, Wang F, Zhang J. Resveratrol improved mitochondrial biogenesis by activating SIRT1\/PGC-1\u03b1 signal pathway in SAP. Sci Rep. 2024;14(1):26216.","journal-title":"Sci Rep"},{"key":"8104_CR314","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13041-015-0101-6","volume":"8","author":"KH Choi","year":"2015","unstructured":"Choi KH, Park MS, Kim HS, Kim KT, Kim HS, Kim JT, et al. Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats. Mol Brain. 2015;8:9.","journal-title":"Mol Brain"},{"key":"8104_CR315","doi-asserted-by":"crossref","unstructured":"Dieter F, Esselun C, Eckert GP. Redox active \u03b1-lipoic acid differentially improves mitochondrial dysfunction in a cellular model of alzheimer and its control cells. Int J Mol Sci. 2022;23(16).","DOI":"10.3390\/ijms23169186"},{"issue":"5","key":"8104_CR316","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.3892\/etm.2021.10666","volume":"22","author":"A Petca","year":"2021","unstructured":"Petca A, Bot M, Maru N, Calo IG, Borislavschi A, Dumitrascu MC, et al. Benefits of \u03b1-lipoic acid in high-risk pregnancies (review). Exp Ther Med. 2021;22(5):1232.","journal-title":"Exp Ther Med"},{"key":"8104_CR317","doi-asserted-by":"publisher","first-page":"102667","DOI":"10.1016\/j.arr.2025.102667","volume":"104","author":"P Wen","year":"2025","unstructured":"Wen P, Sun Z, Gou F, Wang J, Fan Q, Zhao D, et al. Oxidative stress and mitochondrial impairment: key drivers in neurodegenerative disorders. Ageing Res Rev. 2025;104:102667.","journal-title":"Ageing Res Rev"},{"key":"8104_CR318","doi-asserted-by":"publisher","first-page":"101846","DOI":"10.1016\/j.mito.2024.101846","volume":"75","author":"X Du","year":"2024","unstructured":"Du X, Zeng Q, Luo Y, He L, Zhao Y, Li N, et al. Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction. Mitochondrion. 2024;75:101846.","journal-title":"Mitochondrion"},{"key":"8104_CR319","doi-asserted-by":"publisher","first-page":"176003","DOI":"10.1016\/j.ejphar.2023.176003","volume":"957","author":"Q You","year":"2023","unstructured":"You Q, Lan XB, Liu N, Du J, Ma L, Yang JM, et al. Neuroprotective strategies for neonatal hypoxic-ischemic brain damage: current status and challenges. Eur J Pharmacol. 2023;957:176003.","journal-title":"Eur J Pharmacol"},{"key":"8104_CR320","doi-asserted-by":"crossref","unstructured":"Bhatti JS, Bhatti GK, Reddy PH. Mitochondrial dysfunction and oxidative stress in metabolic disorders - a step towards mitochondria based therapeutic strategies. biochimica et biophysica acta molecular basis of disease. 2017;1863(5):1066\u201377.","DOI":"10.1016\/j.bbadis.2016.11.010"},{"issue":"5","key":"8104_CR321","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1203\/01.pdr.0000215045.91122.44","volume":"59","author":"M Jatana","year":"2006","unstructured":"Jatana M, Singh I, Singh AK, Jenkins D. Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats. Pediatr Res. 2006;59(5):684\u201389.","journal-title":"Pediatr Res"},{"key":"8104_CR322","doi-asserted-by":"crossref","unstructured":"Kesidou E, Bitsina C, Chatzisotiriou A, Theotokis P, Dandi E, Tata DA, et al. N-Acetylcysteine administration attenuates sensorimotor impairments following neonatal hypoxic-ischemic brain injury in rats. Int J Mol Sci. 2022;23(24).","DOI":"10.3390\/ijms232416175"},{"key":"8104_CR323","doi-asserted-by":"crossref","unstructured":"Zhong Y, Jin R, Luo R, Liu J, Ren L, Zhang Y, et al. Diosgenin targets CaMKK2 to alleviate type II diabetic nephropathy through improving autophagy, Mitophagy and mitochondrial dynamics. Nutrients. 2023;15(16).","DOI":"10.3390\/nu15163554"},{"key":"8104_CR324","doi-asserted-by":"crossref","unstructured":"Campos JC, Marchesi Bozi LH, Krum B, Grassmann Bechara LR, Ferreira ND, Arini GS, et al. Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics. Proc Natl Acad Sci U S A. 2023;120(2):e2204750120.","DOI":"10.1073\/pnas.2204750120"}],"container-title":["Journal of Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12967-026-08104-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12967-026-08104-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12967-026-08104-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T04:29:46Z","timestamp":1779769786000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12967-026-08104-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,10]]},"references-count":324,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["8104"],"URL":"https:\/\/doi.org\/10.1186\/s12967-026-08104-2","relation":{},"ISSN":["1479-5876"],"issn-type":[{"value":"1479-5876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,10]]},"assertion":[{"value":"22 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"698"}}