{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:12:52Z","timestamp":1790388772224,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T00:00:00Z","timestamp":1406678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Magnetic Resonance"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/s12968-014-0056-2","type":"journal-article","created":{"date-parts":[[2014,7,29]],"date-time":"2014-07-29T07:35:13Z","timestamp":1406619313000},"page":"56","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["Left ventricular shape variation in asymptomatic populations: the multi-ethnic study of atherosclerosis"],"prefix":"10.1016","volume":"16","author":[{"given":"Pau","family":"Medrano-Gracia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett R","family":"Cowan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharath","family":"Ambale-Venkatesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A","family":"Bluemke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Eng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Paul","family":"Finn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carissa G","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao AC","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avan","family":"Suinesiaputra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair A","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1186\/s12968-014-0056-2_bib1","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1161\/01.CIR.101.25.2981","article-title":"Left ventricular remodeling after myocardial infarction: pathophysiology and therapy","volume":"101","author":"Sutton","year":"2000","journal-title":"Circulation"},{"key":"10.1186\/s12968-014-0056-2_bib2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1161\/01.CIR.76.1.44","article-title":"Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction","volume":"76","author":"White","year":"1987","journal-title":"Circulation"},{"key":"10.1186\/s12968-014-0056-2_bib3","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.amjcard.2004.07.110","article-title":"Relation of left ventricular sphericity to 10-year survival after acute myocardial infarction","volume":"94","author":"Wong","year":"2004","journal-title":"Am J Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib4","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.ehj.2004.02.030","article-title":"Early identification of left ventricular remodelling after myocardial infarction, assessed by transthoracic 3D echocardiography","volume":"25","author":"Mannaerts","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1186\/s12968-014-0056-2_bib5","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1067\/mhj.2001.113218","article-title":"Prognostic implications of left ventricular hypertrophy","volume":"141","author":"Vakili","year":"2001","journal-title":"Am Heart J"},{"key":"10.1186\/s12968-014-0056-2_bib6","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJM199705083361903","article-title":"Left ventricular dilatation and the risk of congestive heart failure in people without myocardial infarction","volume":"336","author":"Vasan","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1186\/s12968-014-0056-2_bib7","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/0002-9149(92)90052-Z","article-title":"Prognostic implications of subclinical left ventricular dilatation and systolic dysfunction in men free of overt cardiovascular disease (the Framingham Heart Study)","volume":"70","author":"Lauer","year":"1992","journal-title":"Am J Cardiol"},{"issue":"Suppl 6","key":"10.1186\/s12968-014-0056-2_bib8","doi-asserted-by":"crossref","first-page":"S135","DOI":"10.1097\/00005344-198700106-00018","article-title":"Left ventricular hypertrophy and risk of cardiac failure: insights from the Framingham Study","volume":"10","author":"Kannel","year":"1987","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1186\/s12968-014-0056-2_bib9","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/aje\/kwf113","article-title":"Multi-ethnic study of atherosclerosis: objectives and design","volume":"156","author":"Bild","year":"2002","journal-title":"Am J Epidemiol"},{"key":"10.1186\/s12968-014-0056-2_bib10","doi-asserted-by":"crossref","first-page":"S357","DOI":"10.2214\/AJR.04.1868","article-title":"Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity","volume":"186","author":"Natori","year":"2006","journal-title":"AJR Am J Roentgenol"},{"key":"10.1186\/s12968-014-0056-2_bib11","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1093\/bioinformatics\/btr360","article-title":"The Cardiac Atlas Project\u2013an imaging database for computational modeling and statistical atlases of the heart","volume":"27","author":"Fonseca","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1186\/s12968-014-0056-2_bib12","first-page":"486","article-title":"Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants","volume":"46","author":"Oishi","year":"2009","journal-title":"Neuro Image"},{"key":"10.1186\/s12968-014-0056-2_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cercor\/11.1.1","article-title":"Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas","volume":"11","author":"Thompson","year":"2001","journal-title":"Cerebral Cortex"},{"key":"10.1186\/s12968-014-0056-2_bib14","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1113\/expphysiol.2008.044081","article-title":"Computational cardiac atlases: from patient to population and back","volume":"94","author":"Young","year":"2009","journal-title":"Exp Physiol"},{"key":"10.1186\/s12968-014-0056-2_bib15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1161\/CIRCULATIONAHA.112.126920","article-title":"Preterm heart in adult life: cardiovascular magnetic resonance reveals distinct differences in left ventricular mass, geometry, and function","volume":"127","author":"Lewandowski","year":"2013","journal-title":"Circulation"},{"key":"10.1186\/s12968-014-0056-2_bib16","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/jmri.22714","article-title":"Mapping system for coregistration of cardiac MRI and ex vivo tissue sampling","volume":"34","author":"Young","year":"2011","journal-title":"J Magn Reson Imaging"},{"key":"10.1186\/s12968-014-0056-2_bib17","series-title":"FIMH; London","first-page":"433","article-title":"Large Scale Left Ventricular Shape Atlas Using Automated Model Fitting to Contours","author":"Medrano-Gracia","year":"2013"},{"key":"10.1186\/s12968-014-0056-2_bib18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1148\/radiology.216.2.r00au14597","article-title":"Left ventricular mass and volume: fast calculation with guide-point modeling on MR images","volume":"216","author":"Young","year":"2000","journal-title":"Radiology"},{"key":"10.1186\/s12968-014-0056-2_bib19","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1107\/S0567739476001873","article-title":"A solution for the best rotation to relate two sets of vectors","volume":"32","author":"Kabsch","year":"1976","journal-title":"Acta Crystallogr A"},{"issue":"2","key":"10.1186\/s12968-014-0056-2_bib20","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.2517-6161.1991.tb01825.x","article-title":"Procrustes methods in the statistical analysis of shape","volume":"53","author":"Goodall","year":"1991","journal-title":"J Roy Stat Soc B"},{"key":"10.1186\/s12968-014-0056-2_bib21","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1109\/TMI.2004.842458","article-title":"Parameter distribution models for estimation of population based left ventricular deformation using sparse fiducial markers","volume":"24","author":"Remme","year":"2005","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1186\/s12968-014-0056-2_bib22","series-title":"Principles of multivariate analysis","author":"Krzanowski","year":"2000"},{"key":"10.1186\/s12968-014-0056-2_bib23","doi-asserted-by":"crossref","first-page":"19313","DOI":"10.1073\/pnas.1313476110","article-title":"Revised standards for statistical evidence","volume":"110","author":"Johnson","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1186\/s12968-014-0056-2_bib24","series-title":"The handbook of Research Synthesis","first-page":"231","article-title":"Parametric Measures of Effect Size","author":"Rosenthal","year":"1994"},{"key":"10.1186\/s12968-014-0056-2_bib25","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1016\/j.jacc.2008.09.014","article-title":"The relationship of left ventricular mass and geometry to incident cardiovascular events: the MESA (Multi-Ethnic Study of Atherosclerosis) study","volume":"52","author":"Bluemke","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib26","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1016\/j.jacc.2006.03.072","article-title":"Traditional cardiovascular risk factors in relation to left ventricular mass, volume, and systolic function by cardiac magnetic resonance imaging: the Multiethnic Study of Atherosclerosis","volume":"48","author":"Heckbert","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib27","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.amjcard.2009.07.018","article-title":"Left ventricular mass and volume with telmisartan, ramipril, or combination in patients with previous atherosclerotic events or with diabetes mellitus (from the ONgoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial [ONTARGET])","volume":"104","author":"Cowan","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib28","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/10976640600572889","article-title":"Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance","volume":"8","author":"Maceira","year":"2006","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-014-0056-2_bib29","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/0735-1097(92)90455-V","article-title":"Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure","volume":"20","author":"Kono","year":"1992","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib30","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/0735-1097(92)90617-V","article-title":"Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension","volume":"19","author":"Ganau","year":"1992","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib31","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1023\/B:MCBI.0000044387.04670.81","article-title":"Expression of matrix metalloproteinase activity in idiopathic dilated cardiomyopathy: a marker of cardiac dilatation","volume":"264","author":"Reddy","year":"2004","journal-title":"Mol Cell Biochem"},{"key":"10.1186\/s12968-014-0056-2_bib32","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/0735-1097(94)00473-4","article-title":"Prognosis of left ventricular geometric patterns in the Framingham Heart Study","volume":"25","author":"Krumholz","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-014-0056-2_bib33","first-page":"383","article-title":"Cardiac anchoring in MRI through context modeling","volume":"13","author":"Lu","year":"2010","journal-title":"Med Image Comput Comput Assist Interv"},{"key":"10.1186\/s12968-014-0056-2_bib34","series-title":"Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges; 2012","first-page":"88","article-title":"Left Ventricular Segmentation Challenge From Cardiac MRI: A Collation Study","author":"Suinesiaputra","year":"2011"},{"key":"10.1186\/s12968-014-0056-2_bib35","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1532-429X-15-80","article-title":"Atlas-based Analysis of Cardiac Shape and Function: Correction of Regional Shape Bias due to Imaging Protocol for Population Studies","volume":"15","author":"Medrano-Gracia","year":"2013","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-014-0056-2_bib36","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1532-429X-15-36","article-title":"Quantification of left ventricular trabeculae using fractal analysis","volume":"15","author":"Captur","year":"2013","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-014-0056-2_bib37","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1161\/CIRCIMAGING.110.959171","article-title":"Changes in mitral annular geometry and dynamics with beta-blockade in patients with degenerative mitral valve disease","volume":"3","author":"Ennis","year":"2010","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1186\/s12968-014-0056-2_bib38","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.jcmg.2010.04.013","article-title":"In-line automated tracking for ventricular function with magnetic resonance imaging","volume":"3","author":"Li","year":"2010","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1186\/s12968-014-0056-2_bib39","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1109\/10.135547","article-title":"Estimation of epicardial strain using the motions of coronary bifurcations in biplane cineangiography","volume":"39","author":"Young","year":"1992","journal-title":"IEEE Trans Biomed Eng"},{"key":"10.1186\/s12968-014-0056-2_bib40","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1109\/TMI.2002.804427","article-title":"A study of the motion and deformation of the heart due to respiration","volume":"21","author":"McLeish","year":"2002","journal-title":"IEEE Trans Med Imaging"}],"container-title":["Journal of Cardiovascular Magnetic Resonance"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12968-014-0056-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12968-014-0056-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097664723001230?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097664723001230?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12968-014-0056-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12968-014-0056-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:55:53Z","timestamp":1761094553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097664723001230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S1097664723001230"],"URL":"https:\/\/doi.org\/10.1186\/s12968-014-0056-2","relation":{},"ISSN":["1097-6647"],"issn-type":[{"value":"1097-6647","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left ventricular shape variation in asymptomatic populations: the multi-ethnic study of atherosclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Magnetic Resonance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s12968-014-0056-2","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 THE AUTHORS. Published by Elsevier Inc on behalf of the Society for Cardiovascular Magnetic Resonance","name":"copyright","label":"Copyright"}],"article-number":"56"}}