{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:07:57Z","timestamp":1793196477979,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T00:00:00Z","timestamp":1546473600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["FS\/16\/28\/32327"],"award-info":[{"award-number":["FS\/16\/28\/32327"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL122560"],"award-info":[{"award-number":["R01HL122560"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Magnetic Resonance"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1186\/s12968-018-0514-3","type":"journal-article","created":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T19:33:07Z","timestamp":1546457587000},"page":"2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Prognostic and functional implications of left atrial late gadolinium enhancement\u00a0cardiovascular magnetic resonance"],"prefix":"10.1016","volume":"21","author":[{"given":"Michael","family":"Quail","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Grunseich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"Baldassarre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Mojibian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Marieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cornfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Soufer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert J.","family":"Sinusas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana C.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1186\/s12968-018-0514-3_bib1","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1161\/CIRCULATIONAHA.108.811877","article-title":"Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation","volume":"119","author":"Oakes","year":"2009","journal-title":"Circulation"},{"key":"10.1186\/s12968-018-0514-3_bib2","doi-asserted-by":"crossref","unstructured":"Habibi M, Lima JA, Khurram IM, Zimmerman SL, Zipunnikov V, Fukumoto K, Spragg D, Ashikaga H, Rickard J, Marine JE, et al. Association of left atrial function and left atrial enhancement in patients with atrial fibrillation: cardiac magnetic resonance study. Circ Cardiovasc Imaging. 2015;8.","DOI":"10.1161\/CIRCIMAGING.114.002769"},{"key":"10.1186\/s12968-018-0514-3_bib3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jcmg.2016.01.015","article-title":"CMR-verified lower LA strain in the presence of regional atrial fibrosis in atrial fibrillation","volume":"10","author":"Peters","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1186\/s12968-018-0514-3_bib4","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.hrthm.2013.04.030","article-title":"Automated analysis of atrial late gadolinium enhancement imaging that correlates with endocardial voltage and clinical outcomes: a 2-center study","volume":"10","author":"Malcolme-Lawes","year":"2013","journal-title":"Heart Rhythm"},{"key":"10.1186\/s12968-018-0514-3_bib5","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1016\/j.hrthm.2012.08.039","article-title":"Initial experience with magnetic resonance imaging of atrial scar and co-registration with electroanatomic voltage mapping during atrial fibrillation: success and limitations","volume":"9","author":"Spragg","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1186\/s12968-018-0514-3_bib6","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jacc.2010.09.049","article-title":"Association of left atrial fibrosis detected by delayed-enhancement magnetic resonance imaging and the risk of stroke in patients with atrial fibrillation","volume":"57","author":"Daccarett","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-018-0514-3_bib7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.jacc.2017.07.758","article-title":"Left atrial fibrosis and risk of cerebrovascular and cardiovascular events in patients with atrial fibrillation","volume":"70","author":"King","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-018-0514-3_bib8","first-page":"25","article-title":"The association of pre-existing left atrial fibrosis with clinical variables in patients referred for catheter ablation of atrial fibrillation","volume":"8","author":"Dewire","year":"2014","journal-title":"Clin Med Insights Cardiol"},{"key":"10.1186\/s12968-018-0514-3_bib9","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jcmg.2008.10.016","article-title":"Recurrence of atrial fibrillation correlates with the extent of post-procedural late gadolinium enhancement: a pilot study","volume":"2","author":"Peters","year":"2009","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1186\/s12968-018-0514-3_bib10","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1001\/jama.2014.3","article-title":"Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study","volume":"311","author":"Marrouche","year":"2014","journal-title":"JAMA"},{"key":"10.1186\/s12968-018-0514-3_bib11","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12968-018-0449-8","article-title":"Optimization of late gadolinium enhancement cardiovascular magnetic resonance imaging of post-ablation atrial scar: a cross-over study","volume":"20","author":"Chubb","year":"2018","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-018-0514-3_bib12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12968-018-0438-y","article-title":"The reproducibility of late gadolinium enhancement cardiovascular magnetic resonance imaging of post-ablation atrial scar: a cross-over study","volume":"20","author":"Chubb","year":"2018","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-018-0514-3_bib13","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1148\/radiology.218.1.r01ja50215","article-title":"An improved MR imaging technique for the visualization of myocardial infarction","volume":"218","author":"Simonetti","year":"2001","journal-title":"Radiology"},{"key":"10.1186\/s12968-018-0514-3_bib14","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.114.001002","article-title":"Atrial fibrillation in hypertrophic cardiomyopathy: prevalence, clinical correlations, and mortality in a large high-risk population","volume":"3","author":"Siontis","year":"2014","journal-title":"J Am Heart Assoc"},{"key":"10.1186\/s12968-018-0514-3_bib15","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jama.1994.03510350050036","article-title":"Independent risk-factors for atrial-fibrillation in a population-based cohort - the Framingham heart-study","volume":"271","author":"Benjamin","year":"1994","journal-title":"JAMA-Journal of the American Medical Association"},{"key":"10.1186\/s12968-018-0514-3_bib16","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1161\/01.CIR.96.7.2455","article-title":"Incidence of and risk factors for atrial fibrillation in older adults","volume":"96","author":"Psaty","year":"1997","journal-title":"Circulation"},{"key":"10.1186\/s12968-018-0514-3_bib17","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.carpath.2012.06.001","article-title":"Fibrosis, myocardial crossings, disconnections, abrupt turns, and epicardial reflections: do they play an actual role in human permanent atrial fibrillation? A controlled necropsy study","volume":"22","author":"de Oliveira","year":"2013","journal-title":"Cardiovasc Pathol"},{"key":"10.1186\/s12968-018-0514-3_bib18","doi-asserted-by":"crossref","unstructured":"Habibi M, Samiei S, Ambale Venkatesh B, Opdahl A, Helle-Valle TM, Zareian M, Almeida AL, Choi EY, Wu C, Alonso A, et al. Cardiac magnetic resonance-measured left atrial volume and function and incident atrial fibrillation: results from MESA (multi-ethnic study of atherosclerosis). Circ Cardiovasc Imaging. 2016;9.","DOI":"10.1161\/CIRCIMAGING.115.004299"},{"key":"10.1186\/s12968-018-0514-3_bib19","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/jce.12651","article-title":"Age, atrial fibrillation, and structural heart disease are the main determinants of left atrial fibrosis detected by delayed-enhanced magnetic resonance imaging in a general cardiology population","volume":"26","author":"Cochet","year":"2015","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1186\/s12968-018-0514-3_bib20","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s11886-014-0509-0","article-title":"Rotors as drivers of atrial fibrillation and targets for ablation","volume":"16","author":"Schricker","year":"2014","journal-title":"Curr Cardiol Rep"},{"key":"10.1186\/s12968-018-0514-3_bib21","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1038\/ncpcardio1370","article-title":"Structural remodeling in atrial fibrillation","volume":"5","author":"Corradi","year":"2008","journal-title":"Nature Clinical Practice Cardiovascular Medicine"},{"key":"10.1186\/s12968-018-0514-3_bib22","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jacc.2007.09.064","article-title":"Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation","volume":"51","author":"Burstein","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s12968-018-0514-3_bib23","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/1532-429X-15-105","article-title":"Evaluation of current algorithms for segmentation of scar tissue from late gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge","volume":"15","author":"Karim","year":"2013","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1186\/s12968-018-0514-3_bib24","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.hrthm.2008.02.008","article-title":"Left atrial function and scar after catheter ablation of atrial fibrillation","volume":"5","author":"Wylie","year":"2008","journal-title":"Heart Rhythm"},{"key":"10.1186\/s12968-018-0514-3_bib25","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ijcard.2009.10.032","article-title":"Left atrial wall thickness in paroxysmal atrial fibrillation by multislice-CT is initial marker of structural remodeling and predictor of transition from paroxysmal to chronic form","volume":"148","author":"Nakamura","year":"2011","journal-title":"Int J Cardiol"},{"key":"10.1186\/s12968-018-0514-3_bib26","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.112.000102","article-title":"Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium","volume":"2","author":"Alonso","year":"2013","journal-title":"J Am Heart Assoc"},{"key":"10.1186\/s12968-018-0514-3_bib27","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1053\/euhj.2001.2658","volume":"22","author":"Saoudi","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1186\/s12968-018-0514-3_bib28","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1161\/01.CIR.90.3.1262","article-title":"Sustained atrial tachycardia in adult patients. Electrophysiological characteristics, pharmacological response, possible mechanisms, and effects of radiofrequency ablation","volume":"90","author":"Chen","year":"1994","journal-title":"Circulation"},{"key":"10.1186\/s12968-018-0514-3_bib29","first-page":"397","article-title":"Multifocal atrial tachycardia (chaotic atrial tachycardia)","volume":"42","author":"Lipson","year":"1970","journal-title":"Clinical associations and significance Circulation"},{"key":"10.1186\/s12968-018-0514-3_bib30","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1056\/NEJM196808152790703","article-title":"Multifocal atrial tachycardia. Clinical and electrocardiographic features in 32 patients","volume":"279","author":"Shine","year":"1968","journal-title":"N Engl J Med"},{"key":"10.1186\/s12968-018-0514-3_bib31","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1001\/archinte.1977.03630140017007","article-title":"Multifocal atrial tachycardia","volume":"137","author":"Wang","year":"1977","journal-title":"Arch Intern Med"},{"key":"10.1186\/s12968-018-0514-3_bib32","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1093\/eurheartj\/ehn217","article-title":"New-onset atrial fibrillation is an independent predictor of in-hospital mortality in hospitalized heart failure patients: results of the EuroHeart failure survey","volume":"29","author":"Rivero-Ayerza","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1186\/s12968-018-0514-3_bib33","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMoa1707855","article-title":"Catheter ablation for atrial fibrillation with heart failure","volume":"378","author":"Marrouche","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1186\/s12968-018-0514-3_bib34","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1161\/CIRCULATIONAHA.112.113233","article-title":"Diastolic dysfunction and risk of atrial fibrillation: a mechanistic appraisal","volume":"126","author":"Rosenberg","year":"2012","journal-title":"Circulation"},{"key":"10.1186\/s12968-018-0514-3_bib35","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/europace\/eut147","article-title":"Relationship between left atrial tissue structural remodelling detected using late gadolinium enhancement MRI and left ventricular hypertrophy in patients with atrial fibrillation","volume":"15","author":"Akkaya","year":"2013","journal-title":"Europace"},{"key":"10.1186\/s12968-018-0514-3_bib36","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/echo.13094","article-title":"Correlation of left atrial strain and Doppler measurements with invasive measurement of left ventricular end-diastolic pressure in patients stratified for different values of ejection fraction","volume":"33","author":"Cameli","year":"2016","journal-title":"Echocardiography"},{"key":"10.1186\/s12968-018-0514-3_bib37","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jcmg.2016.08.014","article-title":"LA strain for categorization of LV diastolic dysfunction","volume":"10","author":"Singh","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1186\/s12968-018-0514-3_bib38","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1093\/eurjhf\/hfp112","article-title":"Independent relationship of left atrial size and mortality in patients with heart failure: an individual patient meta-analysis of longitudinal data (MeRGE heart failure)","volume":"11","author":"Rossi","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"10.1186\/s12968-018-0514-3_bib39","doi-asserted-by":"crossref","unstructured":"Hedberg P, Selmeryd J, Leppert J, Henriksen E. Left atrial minimum volume is more strongly associated with N-terminal pro-B-type natriuretic peptide than the left atrial maximum volume in a community-based sample. Int J Cardiovasc Imaging. 2015.","DOI":"10.1007\/s10554-015-0800-1"},{"key":"10.1186\/s12968-018-0514-3_bib40","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/ehjci\/jes118","article-title":"Left atrial volume and function in patients following ST elevation myocardial infarction and the association with clinical outcome: a cardiovascular magnetic resonance study","volume":"14","author":"Lonborg","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1186\/s12968-018-0514-3_bib41","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2014-000223","article-title":"Predictors and prognostic value of left atrial remodelling after acute myocardial infarction","volume":"2","author":"Kyhl","year":"2015","journal-title":"Open Heart"},{"key":"10.1186\/s12968-018-0514-3_bib42","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1016\/j.ejrad.2009.12.012","article-title":"Correlation between myocardial fibrosis and the occurrence of atrial fibrillation in hypertrophic cardiomyopathy: a cardiac magnetic resonance imaging study","volume":"75","author":"Pujadas","year":"2010","journal-title":"Eur J Radiol"},{"key":"10.1186\/s12968-018-0514-3_bib43","first-page":"988","article-title":"Relation of late gadolinium enhancement in cardiac magnetic resonance on the diastolic volume recovery of left ventricle with hypertrophic cardiomyopathy","volume":"6","author":"Chen","year":"2014","journal-title":"J Thorac Dis"},{"key":"10.1186\/s12968-018-0514-3_bib44","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1253\/circj.72.378","article-title":"Correlation between late gadolinium enhancement and diastolic function in hypertrophic cardiomyopathy assessed by magnetic resonance imaging","volume":"72","author":"Motoyasu","year":"2008","journal-title":"Circ J"},{"key":"10.1186\/s12968-018-0514-3_bib45","first-page":"H542","article-title":"Left atrial aging: a cardiac magnetic resonance feature-tracking study","volume":"310","author":"Evin","year":"2016","journal-title":"Am J Phys Heart Circ Phys"},{"key":"10.1186\/s12968-018-0514-3_bib46","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.hrthm.2016.05.028","article-title":"EHRA\/HRS\/APHRS\/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication","volume":"14","author":"Goette","year":"2017","journal-title":"Heart Rhythm"},{"key":"10.1186\/s12968-018-0514-3_bib47","doi-asserted-by":"crossref","unstructured":"Hu C, Huber S, Latif SR, Santacana-Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. REPAIRit: improving myocardial nulling and ghosting artifacts of 3D navigator-gated late gadolinium enhancement imaging during arrhythmia. J Magn Reson Imaging. 2018. https:\/\/doi.org\/10.1002\/jmri.26284.","DOI":"10.1002\/jmri.26284"}],"container-title":["Journal of Cardiovascular Magnetic Resonance"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12968-018-0514-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12968-018-0514-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097664723001758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097664723001758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12968-018-0514-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:57:28Z","timestamp":1761094648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097664723001758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1097664723001758"],"URL":"https:\/\/doi.org\/10.1186\/s12968-018-0514-3","relation":{},"ISSN":["1097-6647"],"issn-type":[{"value":"1097-6647","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic and functional implications of left atrial late gadolinium enhancement\u00a0cardiovascular magnetic resonance","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Magnetic Resonance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s12968-018-0514-3","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2019 THE AUTHORS. Published by Elsevier Inc on behalf of the Society for Cardiovascular Magnetic Resonance","name":"copyright","label":"Copyright"}],"article-number":"2"}}