{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T03:34:45Z","timestamp":1768707285364,"version":"3.49.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T00:00:00Z","timestamp":1559779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T00:00:00Z","timestamp":1559779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Rheumatol"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12969-019-0329-2","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T14:03:09Z","timestamp":1559829789000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Relapsing periodic arthritis, palindromic rheumatism and MEFV gene-related variants alleles in children"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5539-4404","authenticated-orcid":false,"given":"Farhad","family":"Salehzadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuchehr","family":"Barak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roghayeh","family":"Nematdoust Haghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,6,6]]},"reference":[{"issue":"5","key":"329_CR1","doi-asserted-by":"publisher","first-page":"569","DOI":"10.2217\/ijr.13.51","volume":"8","author":"S Cabrera-villalba","year":"2013","unstructured":"Cabrera-villalba S, Sanmarti R. Palindromic rheumatism: a reappraisal. Int J Clin Rheumatol. 2013;8(5):569\u201377.","journal-title":"Int J Clin Rheumatol"},{"issue":"1","key":"329_CR2","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s12969-018-0227-z","volume":"16","author":"Y Butbul-Aviel","year":"2018","unstructured":"Butbul-Aviel Y, Uziel Y, Hezkelo N, Brik R, Amarilyo G. Is palindromic rheumatism amongst children a benign disease. Pediatr Rheumatol. 2018;16(1):12.","journal-title":"Pediatr Rheumatol"},{"key":"329_CR3","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1177\/014107688107400713","volume":"74","author":"HG Hardo","year":"1981","unstructured":"Hardo HG. Palindromic rheumatism: a review. J R Soc Med. 1981;74:521\u20134.","journal-title":"J R Soc Med"},{"key":"329_CR4","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1001\/archinte.1944.00210160025004","volume":"73","author":"PS Hench","year":"1944","unstructured":"Hench PS, Rosenberg EF. Palindromic rheumatism. Arch Intern Med. 1944;73:293\u2013321.","journal-title":"Arch Intern Med"},{"issue":"1","key":"329_CR5","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s10067-009-1280-2","volume":"29","author":"P Kaushik","year":"2010","unstructured":"Kaushik P. Palindromic rheumatism: a descriptive report of seven cases from North Dakota and a short review of literature. Clin Rheumatol. 2010;29(1):83\u20136.","journal-title":"Clin Rheumatol."},{"key":"329_CR6","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1136\/ard.25.4.307","volume":"25","author":"S Mattingly","year":"1966","unstructured":"Mattingly S. Palindromic rheumatism. Ann Rheum Dis. 1966;25:307\u201317.","journal-title":"Ann Rheum Dis"},{"key":"329_CR7","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/0002-9343(92)90177-D","volume":"93","author":"PA Guerne","year":"1992","unstructured":"Guerne PA, Weisman MH. Palindromic rheumatism: part of or apart from the spectrum of rheumatoid arthritis. Am J Med. 1992;93:451\u201360.","journal-title":"Am J Med"},{"key":"329_CR8","unstructured":"Familial Mediterranean fever. \n                    https:\/\/ghr.nlm.nih.gov\/medgene\/45811\n                    \n                  ."},{"issue":"4","key":"329_CR9","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/S0092-8674(00)80539-5","volume":"90","author":"Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever","year":"1997","unstructured":"Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The international FMF consortium. Cell. 1997;90(4):797\u2013807.","journal-title":"Cell"},{"key":"329_CR10","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/978-4-431-56039-5_5","volume-title":"Kawasaki Disease","author":"Jun Abe","year":"2016","unstructured":"Jun Abe, Immunological Abnormalities and Use of Biomarkers and Cytokines to Predict the Severity of Kawasaki Disease. In: Kawasaki Disease. (Ben Tsutomu Saji ,ed) 1st edition. Springer, January 2017; PP:31-37 DOI: \n                    https:\/\/doi.org\/10.1007\/978-4-431-56039-5_5"},{"issue":"9","key":"329_CR11","first-page":"2014","volume":"30","author":"S Ozen","year":"2003","unstructured":"Ozen S, Bakkaloglu A, Yilmaz E, Duzova A, Balci B, et al. Mutations in the gene for familial Mediterranean fever: do they predispose to inflammation. J Rheumatol. 2003;30(9):2014\u20138.","journal-title":"J Rheumatol"},{"issue":"3","key":"329_CR12","first-page":"197","volume":"4","author":"G Pasero","year":"1986","unstructured":"Pasero G, Barbieri P. Palindromic rheumatism: you just have to think about it! ClinExp Rheumatol. 1986;4(3):197\u20139.","journal-title":"ClinExp Rheumatol"},{"key":"329_CR13","doi-asserted-by":"publisher","first-page":"912137","DOI":"10.1155\/2015\/912137","volume":"2015","author":"F Salehzadeh","year":"2015","unstructured":"Salehzadeh F. Familial Mediterranean fever in Iran: a report from FMF registration center. Int J Rheumatol. 2015;2015:912137.","journal-title":"Int J Rheumatol"},{"issue":"3","key":"329_CR14","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s12041-016-0682-6","volume":"95","author":"M Beheshtian","year":"2016","unstructured":"Beheshtian M, Izadi N, Kriegshauser G, Kahrizi K, Mehr EP, et al. Prevalence of common MEFV mutations and carrier frequencies in a large cohort of Iranian populations. J Genet. 2016;95(3):667\u201374.","journal-title":"J Genet"},{"issue":"8","key":"329_CR15","doi-asserted-by":"publisher","first-page":"2784","DOI":"10.1002\/art.22755","volume":"56","author":"JD Ca\u00f1ete","year":"2007","unstructured":"Ca\u00f1ete JD, Arostegui JI, Queir\u00f3 R, Gratac\u00f3s J, Hern\u00e1ndez MV, et al. An unexpectedly high frequency of MEFV mutations in patients with anti-citrullinated protein antibody-negative palindromic rheumatism. Arthritis Rheum. 2007;56(8):2784\u20138.","journal-title":"Arthritis Rheum"},{"key":"329_CR16","first-page":"1","volume":"12","author":"L Kobayashil","year":"2015","unstructured":"Kobayashil L, Yamazaki Y, Tozawa Y, Ueki M, Takezaki S, et al. Progression of palindromic rheumatis to juvenile idiopathic arthritis in a Japanese girl carryng heterozygous L110p-E148Q substitutions of MEFV gene. Mod Rheumatol. 2015;12:1\u201313.","journal-title":"Mod Rheumatol"},{"issue":"11","key":"329_CR17","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1093\/rheumatology\/kep296","volume":"48","author":"E Ben-Chetrit","year":"2009","unstructured":"Ben-Chetrit E, Peleg H, Aamar S, Heyman SN. The spectrum of MEFV clinical presentations-is it familial Mediterranean fever only? Rheumatology. 2009;48(11):1455\u20139.","journal-title":"Rheumatology"},{"key":"329_CR18","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1007\/s10067-017-3883-3","volume":"37","author":"B Makay","year":"2018","unstructured":"Makay B, G\u00fclez N. Long-term follow-up of paediatric MEFV carriers. Clin Rheumatol. 2018;37:1683\u20137. \n                    https:\/\/doi.org\/10.1007\/s10067-017-3883-3\n                    \n                  .","journal-title":"Clin Rheumatol"}],"container-title":["Pediatric Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12969-019-0329-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12969-019-0329-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12969-019-0329-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T23:16:38Z","timestamp":1591312598000},"score":1,"resource":{"primary":{"URL":"https:\/\/ped-rheum.biomedcentral.com\/articles\/10.1186\/s12969-019-0329-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,6]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["329"],"URL":"https:\/\/doi.org\/10.1186\/s12969-019-0329-2","relation":{},"ISSN":["1546-0096"],"issn-type":[{"value":"1546-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,6]]},"assertion":[{"value":"10 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.The study is complaint with the Helsinki Declaration and was approved by the local Ethics Committee under number (IR.ARUMS.REC.1396.95).Informed consent was obtained from all parents individual participants included in the study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}