{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:23:41Z","timestamp":1772166221917,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T00:00:00Z","timestamp":1597017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T00:00:00Z","timestamp":1597017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Rheumatol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recurrent and relapsing arthritis has been proposed to describe a group of arthritis with recurring and periodic nature, in which the joints are intermittently involved.<\/jats:p>\n                    <jats:p>\n                      This study reports three non-FMF patients with heterozygous\n                      <jats:italic>MEFV<\/jats:italic>\n                      gene mutations and an extraordinary arthritis as a recurrent synovitis of hip (RSH).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      During 16-years from 2003 to 2019 at pediatric rheumatologic clinic among 195 recorded files with chronic oligoarthritis, 3 patients with diagnosis of recurrent synovitis of hip (RSH) were reviewed thoroughly. Peripheral blood was collected from patients and the samples were screened for the 12 common\n                      <jats:italic>MEFV<\/jats:italic>\n                      gene pathogenic variants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This study included three patients, two female and one male with relapsing idiopathic arthritis that has been located on hip joints as a sole manifestation and pathologic findings of\n                      <jats:italic>MEFV<\/jats:italic>\n                      mutations as follow: A744S, V726A, and R761H.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      On the basis of possible role of\n                      <jats:italic>MEFV<\/jats:italic>\n                      gene in different rheumatic disease,\n                      <jats:italic>MEFV<\/jats:italic>\n                      gene related arthritis may be considered as a background of RSH particularly in Mediterranean area.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12969-020-00456-3","type":"journal-article","created":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T14:03:56Z","timestamp":1597068236000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Recurrent synovitis of hip and MEFV gene related arthritis in children"],"prefix":"10.1186","volume":"18","author":[{"given":"Farhad","family":"Salehzadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7369-4942","authenticated-orcid":false,"given":"Mehrdad","family":"Mirzarahimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,10]]},"reference":[{"issue":"5","key":"456_CR1","doi-asserted-by":"publisher","first-page":"569","DOI":"10.2217\/ijr.13.51","volume":"8","author":"S Cabrera-villalba","year":"2013","unstructured":"Cabrera-villalba S, Sanmarti R. 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