{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:33:39Z","timestamp":1791200019174,"version":"4.2.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Rheumatol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Juvenile idiopathic arthritis (JIA) is a heterogeneous group of disorders, including all forms of arthritis, which develops in children who are less than 16\u2009years old. This study aimed to evaluate the clinical and laboratory features of JIA in a single center in Jordan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of the electronic medical records of Pediatric patients diagnosed with JIA based on the International League of Associations for Rheumatology (ILAR) criteria during the period from 2015 to 2019 at the Pediatric Rheumatology Clinic in the Queen Rania Children\u2019s Hospital. All patients were below the age of 14\u2009years at the time of diagnosis and followed for at least 6 months. Collected data consisted of age, gender, age at initial presentation and diagnosis, JIA subtype, laboratory data, treatment options, and outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 210 patients were included in this cohort (94 males and 116 females) with the mean age at diagnosis and mean age at onset of 5.33\u2009\u00b1\u20093.40\u2009years and 5.08\u2009\u00b1\u20093.40\u2009years (range: 7\u2009months \u2013 14\u2009years), respectively. Oligoarticular JIA was the commonest subtype (54.7%), followed by systemic arthritis (17.1%) and polyarticular arthritis (12.3%). ANA was positive in 70 patients (33.6%). Uveitis occurred in 30 (14.2%) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>To the best of our knowledge, this study on this cohort is the first report on JIA in Jordan, in comparison with other regionally and internationally published reports. Oligoarticular JIA was found to be the most common subtype. For detailed knowledge on JIA characteristics and patterns, a population-based, rather than a single center study, should be conducted in Jordan.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12969-021-00572-8","type":"journal-article","created":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T07:02:39Z","timestamp":1623481359000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Juvenile idiopathic arthritis in Jordan: single center experience"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4972-5809","authenticated-orcid":false,"given":"Raed M.","family":"Alzyoud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motasem O.","family":"Alsuweiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba Q.","family":"Almaaitah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bushra N.","family":"Aladaileh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad K.","family":"Alnoubani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel M.","family":"Alwahadneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,12]]},"reference":[{"issue":"2","key":"572_CR1","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s40744-016-0040-4","volume":"3","author":"G Giancane","year":"2016","unstructured":"Giancane G, Consolaro A, Lanni S, Dav\u00ec S, Schiappapietra B, Ravelli A. Juvenile idiopathic arthritis: diagnosis and treatment. Rheumatol Ther. 2016;3(2):187\u2013207. https:\/\/doi.org\/10.1007\/s40744-016-0040-4.","journal-title":"Rheumatol Ther"},{"issue":"9563","key":"572_CR2","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/S0140-6736(07)60363-8","volume":"369","author":"A Ravelli","year":"2007","unstructured":"Ravelli A, Martini A. Juvenile idiopathic arthritis. Lancet. 2007;369(9563):767\u201378. https:\/\/doi.org\/10.1016\/S0140-6736(07)60363-8.","journal-title":"Lancet."},{"issue":"2","key":"572_CR3","first-page":"390","volume":"31","author":"RE Petty","year":"2004","unstructured":"Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International league of associations for rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol. 2004;31(2):390\u20132.","journal-title":"J Rheumatol"},{"issue":"S1","key":"572_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-12-S1-P179","volume":"12","author":"R Dagher","year":"2014","unstructured":"Dagher R, Assi S. Juvenile idiopathic arthritis: a single center Lebanese study. Pediatr Rheumatol Online J. 2014;12(S1):P179. https:\/\/doi.org\/10.1186\/1546-0096-12-S1-P179.","journal-title":"Pediatr Rheumatol Online J"},{"key":"572_CR5","doi-asserted-by":"publisher","first-page":"65","DOI":"10.4103\/MJBL.MJBL_115_18","volume":"16","author":"WE Naser","year":"2019","unstructured":"Naser WE. Assessment of the quality of life of Iraqi children with juvenile idiopathic arthritis: a single-center study. Med J Babylon. 2019;16:65\u20139.","journal-title":"Med J Babylon"},{"key":"572_CR6","unstructured":"Alqahtani YAM. The patterns of juvenile idiopathic arthritis [Internet]. Bahrainmedicalbulletin.com. Available from: https:\/\/www.bahrainmedicalbulletin.com\/SEPT_2020\/SEPT2020_THEPATTERNS.pdf. [cited 2021 Jan 3]"},{"issue":"2","key":"572_CR7","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3923\/jms.2009.98.102","volume":"9","author":"S Salah","year":"2009","unstructured":"Salah S, Hamshary A, Lotfy H, Rahman H. Juvenile idiopathic arthritis, the Egyptian experience. J Med Sci. 2009;9(2):98\u2013102. https:\/\/doi.org\/10.3923\/jms.2009.98.102.","journal-title":"J Med Sci"},{"issue":"1","key":"572_CR8","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s12969-015-0030-z","volume":"13","author":"R Abdwani","year":"2015","unstructured":"Abdwani R, Abdalla E, Al Abrawi S, Al-Zakwani I. Epidemiology of juvenile idiopathic arthritis in Oman. Pediatr Rheumatol Online J. 2015;13(1):33. https:\/\/doi.org\/10.1186\/s12969-015-0030-z.","journal-title":"Pediatr Rheumatol Online J"},{"issue":"Suppl 2","key":"572_CR9","doi-asserted-by":"publisher","first-page":"1243.1","DOI":"10.1136\/annrheumdis-2015-eular.4550","volume":"74","author":"Z Alaya","year":"2015","unstructured":"Alaya Z, El Amri N, Zaghouani H, Baccouche K, Amri D, Belghali S, et al. AB1030 juvenile idiopathic arthritis in Central Tunisia: clinical and therapeutic features (about 54 cases). Ann Rheum Dis. 2015;74(Suppl 2):1243.1\u20131243. https:\/\/doi.org\/10.1136\/annrheumdis-2015-eular.4550.","journal-title":"Ann Rheum Dis"},{"key":"572_CR10","first-page":"7802957","volume":"2016","author":"MH Al-Hemairi","year":"2016","unstructured":"Al-Hemairi MH, Albokhari SM, Muzaffer MA. The pattern of juvenile idiopathic arthritis in a single tertiary center in Saudi Arabia. Int J Inflamm. 2016;2016:7802957.","journal-title":"Int J Inflamm"},{"issue":"10","key":"572_CR11","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1002\/art.38092","volume":"65","author":"S Ringold","year":"2013","unstructured":"Ringold S, Weiss PF, Beukelman T, DeWitt EM, Ilowite NT, Kimura Y, et al. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications: ACR 2013 updated recommendations for the medical treatment of JIA. Arthritis Rheum. 2013;65(10):2499\u2013512. https:\/\/doi.org\/10.1002\/art.38092.","journal-title":"Arthritis Rheum"},{"issue":"11","key":"572_CR12","first-page":"2290","volume":"31","author":"CA Wallace","year":"2004","unstructured":"Wallace CA, Ruperto N, Giannini E. Childhood arthritis and rheumatology research Alliance, pediatric rheumatology international trials organization, pediatric rheumatology collaborative study group. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol. 2004;31(11):2290\u20134.","journal-title":"J Rheumatol"},{"issue":"6","key":"572_CR13","doi-asserted-by":"publisher","first-page":"472","DOI":"10.3109\/03009741003742722","volume":"39","author":"C Modesto","year":"2010","unstructured":"Modesto C, Ant\u00f3n J, Rodriguez B, Bou R, Arnal C, Ros J, et al. Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain). Scand J Rheumatol. 2010;39(6):472\u20139. https:\/\/doi.org\/10.3109\/03009741003742722.","journal-title":"Scand J Rheumatol"},{"issue":"1","key":"572_CR14","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1186\/s13075-019-1994-8","volume":"21","author":"E Berthold","year":"2019","unstructured":"Berthold E, M\u00e5nsson B, Kahn R. Outcome in juvenile idiopathic arthritis: a population-based study from Sweden. Arthritis Res Ther. 2019;21(1):218. https:\/\/doi.org\/10.1186\/s13075-019-1994-8.","journal-title":"Arthritis Res Ther"},{"issue":"1","key":"572_CR15","first-page":"111","volume":"29","author":"E Demirkaya","year":"2011","unstructured":"Demirkaya E, Ozen S, Bilginer Y, Ayaz NA, Makay BB, Unsal E, et al. The distribution of juvenile idiopathic arthritis in the eastern Mediterranean: results from the registry of the Turkish pediatric rheumatology association. Clin Exp Rheumatol. 2011;29(1):111\u20136.","journal-title":"Clin Exp Rheumatol"},{"issue":"9","key":"572_CR16","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.1007\/s00296-013-2707-2","volume":"33","author":"AM Abou El-Soud","year":"2013","unstructured":"Abou El-Soud AM, El-Najjar AR, El-Shahawy EE, Amar HA, Hassan TH, Abd-Allaha SH, et al. Prevalence of juvenile idiopathic arthritis in Sharkia governorate, Egypt: epidemiological study. Rheumatol Int. 2013;33(9):2315\u201322. https:\/\/doi.org\/10.1007\/s00296-013-2707-2.","journal-title":"Rheumatol Int"},{"issue":"4","key":"572_CR17","doi-asserted-by":"publisher","first-page":"413","DOI":"10.5144\/0256-4947.1997.413","volume":"17","author":"S Bahabri","year":"1997","unstructured":"Bahabri S, Al-Sewairi W, Al-Mazyad A, Karrar A, Al-Ballaa S, El-Ramahai K, et al. Juvenile rheumatoid arthritis: the Saudi experience. Ann Saudi Med. 1997;17(4):413\u20138. https:\/\/doi.org\/10.5144\/0256-4947.1997.413.","journal-title":"Ann Saudi Med"},{"issue":"6","key":"572_CR18","doi-asserted-by":"publisher","first-page":"1974","DOI":"10.1002\/art.22709","volume":"56","author":"RK Saurenmann","year":"2007","unstructured":"Saurenmann RK, Rose JB, Tyrrell P, Feldman BM, Laxer RM, Schneider R, et al. Epidemiology of juvenile idiopathic arthritis in a multiethnic cohort: ethnicity as a risk factor. Arthritis Rheum. 2007;56(6):1974\u201384. https:\/\/doi.org\/10.1002\/art.22709.","journal-title":"Arthritis Rheum"},{"issue":"1","key":"572_CR19","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jbspin.2009.11.002","volume":"77","author":"E Solau-Gervais","year":"2010","unstructured":"Solau-Gervais E, Robin C, Gambert C, Troller S, Danner S, Gombert B, et al. Prevalence and distribution of juvenile idiopathic arthritis in a region of Western France. Joint Bone Spine. 2010;77(1):47\u20139. https:\/\/doi.org\/10.1016\/j.jbspin.2009.11.002.","journal-title":"Joint Bone Spine"},{"issue":"5","key":"572_CR20","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3109\/03009748809105276","volume":"17","author":"FA Khuffash","year":"1988","unstructured":"Khuffash FA, Majeed HA. Juvenile rheumatoid arthritis among Arab children. Scand J Rheumatol. 1988;17(5):393\u20135. https:\/\/doi.org\/10.3109\/03009748809105276.","journal-title":"Scand J Rheumatol"},{"issue":"4","key":"572_CR21","first-page":"431","volume":"9","author":"H Ozdogan","year":"1991","unstructured":"Ozdogan H, Kasap\u00e7opur O, Dede H, Arisoy N, Beceren T, Yurdakul S, et al. Juvenile chronic arthritis in a Turkish population. Clin Exp Rheumatol. 1991;9(4):431\u20135.","journal-title":"Clin Exp Rheumatol"},{"issue":"2","key":"572_CR22","first-page":"461","volume":"13","author":"AM Al-Wahadneh","year":"2007","unstructured":"Al-Wahadneh AM, Abu-Zeid AF, Khreisat WH. Juvenile idiopathic oligoarthritis: analysis of 42 cases in Jordan. East Mediterr Health J. 2007;13(2):461\u20134.","journal-title":"East Mediterr Health J"},{"issue":"7","key":"572_CR23","first-page":"1531","volume":"29","author":"C Huemer","year":"2002","unstructured":"Huemer C, Malleson PN, Cabral DA, Huemer M, Falger J, Zidek T, et al. Patterns of joint involvement at onset differentiate oligoarticular juvenile psoriatic arthritis from pauciarticular juvenile rheumatoid arthritis. J Rheumatol. 2002;29(7):1531\u20135.","journal-title":"J Rheumatol"},{"issue":"12","key":"572_CR24","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.3899\/jrheum.130302","volume":"40","author":"ST Angeles-Han","year":"2013","unstructured":"Angeles-Han ST, Pelajo CF, Vogler LB, Rouster-Stevens K, Kennedy C, Ponder L, et al. Risk markers of juvenile idiopathic arthritis-associated uveitis in the childhood arthritis and rheumatology research Alliance (CARRA) registry. J Rheumatol. 2013;40(12):2088\u201396. https:\/\/doi.org\/10.3899\/jrheum.130302.","journal-title":"J Rheumatol"},{"issue":"1","key":"572_CR25","doi-asserted-by":"publisher","first-page":"7","DOI":"10.21608\/ejpa.2018.10417","volume":"16","author":"ZM Hussein","year":"2018","unstructured":"Hussein ZM, Wagdy R, Shawki M, Zohni S, Shehawy I. The pattern of juvenile idiopathic arthritis; a retrospective Egyptian study. Egypt J Pediatric Allergy Immunol. 2018;16(1):7\u201314. https:\/\/doi.org\/10.21608\/ejpa.2018.10417.","journal-title":"Egypt J Pediatric Allergy Immunol"},{"issue":"6","key":"572_CR26","doi-asserted-by":"publisher","first-page":"529","DOI":"10.5144\/0256-4947.2013.529","volume":"33","author":"MM Moued","year":"2013","unstructured":"Moued MM, Al-Saggaf HM, Habib HS, Muzaffer MA. Oligoarticular juvenile idiopathic arthritis among Saudi children. Ann Saudi Med. 2013;33(6):529\u201332. https:\/\/doi.org\/10.5144\/0256-4947.2013.529.","journal-title":"Ann Saudi Med"},{"issue":"6","key":"572_CR27","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1093\/rheumatology\/kem053","volume":"46","author":"A Heiligenhaus","year":"2007","unstructured":"Heiligenhaus A, Niewerth M, Ganser G, Heinz C, Minden K, German Uveitis in Childhood Study Group. Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines. Rheumatology (Oxford). 2007;46(6):1015\u20139.","journal-title":"Rheumatology (Oxford)"},{"issue":"4","key":"572_CR28","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1038\/gene.2012.3","volume":"13","author":"A Ravelli","year":"2012","unstructured":"Ravelli A, Grom AA, Behrens EM, Cron RQ. Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment. Genes Immun. 2012;13(4):289\u201398. https:\/\/doi.org\/10.1038\/gene.2012.3.","journal-title":"Genes Immun"},{"issue":"5","key":"572_CR29","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1080\/14397595.2019.1660026","volume":"30","author":"M \u00c7akan","year":"2020","unstructured":"\u00c7akan M, Karada\u011f \u015eG, Tanatar A, Ayaz NA. The frequency of macrophage activation syndrome and disease course in systemic juvenile idiopathic arthritis. Mod Rheumatol. 2020;30(5):900\u20134. https:\/\/doi.org\/10.1080\/14397595.2019.1660026.","journal-title":"Mod Rheumatol"},{"issue":"11","key":"572_CR30","doi-asserted-by":"publisher","first-page":"936","DOI":"10.3345\/kjp.2010.53.11.936","volume":"53","author":"KN Kim","year":"2010","unstructured":"Kim KN. Treatment of juvenile rheumatoid arthritis. Korean J Pediatr. 2010;53(11):936\u201341. https:\/\/doi.org\/10.3345\/kjp.2010.53.11.936.","journal-title":"Korean J Pediatr"},{"issue":"2","key":"572_CR31","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.berh.2005.11.008","volume":"20","author":"CA Wallace","year":"2006","unstructured":"Wallace CA. Current management of juvenile idiopathic arthritis. Best Pract Res Clin Rheumatol. 2006;20(2):279\u2013300. https:\/\/doi.org\/10.1016\/j.berh.2005.11.008.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"4","key":"572_CR32","doi-asserted-by":"publisher","first-page":"281","DOI":"10.7416\/ai.2017.2152","volume":"29","author":"V Marzetti","year":"2017","unstructured":"Marzetti V, Breda L, Miulli E, Filippetti F, Mancini C, Chiarelli F, et al. Clinical characteristics of juvenile idiopathic arthritis in an area of Central Italy: a population-based study. Ann Ig. 2017;29(4):281\u201392. https:\/\/doi.org\/10.7416\/ai.2017.2152.","journal-title":"Ann Ig"},{"key":"572_CR33","unstructured":"Jones AP, Clayton D, Nkhoma G, Sherratt FC, Peak M, Stones SR, et al. Literature review on the use of corticosteroids in juvenile idiopathic arthritis. NIHR J Libr. 2020;24(36)2:13\u201318."},{"issue":"1","key":"572_CR34","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s12969-018-0255-8","volume":"16","author":"G Ferrara","year":"2018","unstructured":"Ferrara G, Mastrangelo G, Barone P, La Torre F, Martino S, Pappagallo G, et al. Methotrexate in juvenile idiopathic arthritis: advice and recommendations from the MARAJIA expert consensus meeting. Pediatr Rheumatol Online J. 2018;16(1):46. https:\/\/doi.org\/10.1186\/s12969-018-0255-8.","journal-title":"Pediatr Rheumatol Online J"},{"issue":"S1","key":"572_CR35","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-8-S1-P64","volume":"8","author":"AF Mour\u00e3o","year":"2010","unstructured":"Mour\u00e3o AF, Rodrigues A, Vinagre F, Sousa E, Polido-Pereira J, Macieira C, et al. Eight years of experience with biological treatment in juvenile idiopathic arthritis. J Transl Med. 2010;8(S1):P64. https:\/\/doi.org\/10.1186\/1479-5876-8-S1-P64.","journal-title":"J Transl Med"},{"issue":"1","key":"572_CR36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5152\/tpa.2015.2229","volume":"50","author":"\u00d6 Kasap\u00e7opur","year":"2015","unstructured":"Kasap\u00e7opur \u00d6, Barut K. Treatment in juvenile rheumatoid arthritis and new treatment options. Turk Pediatri Ars. 2015;50(1):1\u201310. https:\/\/doi.org\/10.5152\/tpa.2015.2229.","journal-title":"Turk Pediatri Ars"},{"issue":"9","key":"572_CR37","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1007\/s10067-011-1720-7","volume":"30","author":"EI Alexeeva","year":"2011","unstructured":"Alexeeva EI, Valieva SI, Bzarova TM, Semikina EL, Isaeva KB, Lisitsyn AO, et al. Efficacy and safety of repeat courses of rituximab treatment in patients with severe refractory juvenile idiopathic arthritis. Clin Rheumatol. 2011;30(9):1163\u201372. https:\/\/doi.org\/10.1007\/s10067-011-1720-7.","journal-title":"Clin Rheumatol"},{"issue":"4","key":"572_CR38","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.jmii.2012.03.006","volume":"46","author":"C-C Shen","year":"2013","unstructured":"Shen C-C, Yeh K-W, Ou L-S, Yao T-C, Chen L-C, Huang J-L. Clinical features of children with juvenile idiopathic arthritis using the ILAR classification criteria: a community-based cohort study in Taiwan. J Microbiol Immunol Infect. 2013;46(4):288\u201394. https:\/\/doi.org\/10.1016\/j.jmii.2012.03.006.","journal-title":"J Microbiol Immunol Infect"},{"issue":"12","key":"572_CR39","doi-asserted-by":"publisher","first-page":"3727","DOI":"10.1093\/rheumatology\/keaa118","volume":"59","author":"A Chhabra","year":"2020","unstructured":"Chhabra A, Robinson C, Houghton K, Cabral DA, Morishita K, Tucker LB, et al. Long-term outcomes and disease course of children with juvenile idiopathic arthritis in the ReACCh-out cohort: a two-center experience. Rheumatology (Oxford). 2020;59(12):3727\u201330. https:\/\/doi.org\/10.1093\/rheumatology\/keaa118.","journal-title":"Rheumatology (Oxford)"}],"container-title":["Pediatric Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12969-021-00572-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12969-021-00572-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12969-021-00572-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T07:04:23Z","timestamp":1623481463000},"score":1,"resource":{"primary":{"URL":"https:\/\/ped-rheum.biomedcentral.com\/articles\/10.1186\/s12969-021-00572-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,12]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["572"],"URL":"https:\/\/doi.org\/10.1186\/s12969-021-00572-8","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-103495\/v2","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-103495\/v1","asserted-by":"object"}]},"ISSN":["1546-0096"],"issn-type":[{"value":"1546-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,12]]},"assertion":[{"value":"3 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study has been approved by the Royal Medical Services Ethical Committee, a written consent form to participate in this study was signed by the patient parents.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors have reviewed the manuscript and agreed for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors have no competing conflicts to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"90"}}