{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:14:06Z","timestamp":1790374446956,"version":"4.1.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005761","name":"Sahlgrenska Akademin","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005761","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005754","name":"Sahlgrenska Universitetssjukhuset","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005754","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007212","name":"V\u00e4stra G\u00f6talandsregionen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007212","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003849","name":"IngaBritt och Arne Lundbergs Forskningsstiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003849","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neuroinflammation"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12974-017-0907-5","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T08:44:59Z","timestamp":1499676299000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["CXCL11 production in cerebrospinal fluid distinguishes herpes simplex meningitis from herpes simplex encephalitis"],"prefix":"10.1186","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9762-7296","authenticated-orcid":false,"given":"Liza","family":"Lind","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Studahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linn","family":"Persson Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Eriksson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,7,10]]},"reference":[{"key":"907_CR1","doi-asserted-by":"crossref","unstructured":"Wald A, Corey L. Persistence in the population: epidemiology, transmission. In: Arvin A, Campadelli-Fiume G, Mocarski E, et al. editors. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007.","DOI":"10.1017\/CBO9780511545313.037"},{"issue":"7","key":"907_CR2","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.3201\/eid1507.080716","volume":"15","author":"K Kallio-Laine","year":"2009","unstructured":"Kallio-Laine K, et al. Recurrent lymphocytic meningitis positive for herpes simplex virus type 2. Emerg Infect Dis. 2009;15(7):1119\u201322.","journal-title":"Emerg Infect Dis"},{"issue":"11-12","key":"907_CR3","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1080\/00365540802235741","volume":"40","author":"E Franzen-Rohl","year":"2008","unstructured":"Franzen-Rohl E, et al. High diagnostic yield by CSF-PCR for entero- and herpes simplex viruses and TBEV serology in adults with acute aseptic meningitis in Stockholm. Scand J Infect Dis. 2008;40(11-12):914\u201321.","journal-title":"Scand J Infect Dis"},{"issue":"5","key":"907_CR4","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1001\/archneur.65.5.596","volume":"65","author":"JR Berger","year":"2008","unstructured":"Berger JR, Houff S. Neurological complications of herpes simplex virus type 2 infection. Arch Neurol. 2008;65(5):596\u2013600.","journal-title":"Arch Neurol"},{"issue":"4","key":"907_CR5","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1086\/341979","volume":"35","author":"JP Simko","year":"2002","unstructured":"Simko JP, et al. Differences in laboratory findings for cerebrospinal fluid specimens obtained from patients with meningitis or encephalitis due to herpes simplex virus (HSV) documented by detection of HSV DNA. Clin Infect Dis. 2002;35(4):414\u20139.","journal-title":"Clin Infect Dis"},{"key":"907_CR6","unstructured":"Whitley, R.J., Herpes simplex virus, in infections of the central nervous system, W.M. Scheld, R.J. Whitley, and C.M. Marra, Editors. Philadelphia: Lippincott Williams & Wilkins; 2004"},{"issue":"2","key":"907_CR7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s13365-014-0312-0","volume":"21","author":"E Jennische","year":"2015","unstructured":"Jennische E, et al. The anterior commissure is a pathway for contralateral spread of herpes simplex virus type 1 after olfactory tract infection. J Neurovirol. 2015;21(2):129\u201347.","journal-title":"J Neurovirol"},{"issue":"1","key":"907_CR8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1086\/514494","volume":"25","author":"RB Domingues","year":"1997","unstructured":"Domingues RB, et al. Evaluation of the range of clinical presentations of herpes simplex encephalitis by using polymerase chain reaction assay of cerebrospinal fluid samples. Clin Infect Dis. 1997;25(1):86\u201391.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"907_CR9","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1086\/341405","volume":"35","author":"F Raschilas","year":"2002","unstructured":"Raschilas F, et al. Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis. 2002;35(3):254\u201360.","journal-title":"Clin Infect Dis"},{"issue":"6","key":"907_CR10","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1001\/archneur.1990.00530060054017","volume":"47","author":"B Gordon","year":"1990","unstructured":"Gordon B, et al. Long-term cognitive sequelae of acyclovir-treated herpes simplex encephalitis. Arch Neurol. 1990;47(6):646\u20137.","journal-title":"Arch Neurol"},{"issue":"2","key":"907_CR11","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/infdis\/162.2.322","volume":"162","author":"T Bergstrom","year":"1990","unstructured":"Bergstrom T, et al. Primary and recurrent herpes simplex virus type 2-induced meningitis. J Infect Dis. 1990;162(2):322\u201330.","journal-title":"J Infect Dis"},{"issue":"4","key":"907_CR12","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1080\/00365540110080485","volume":"34","author":"E Aurelius","year":"2002","unstructured":"Aurelius E, et al. Neurologic morbidity after herpes simplex virus type 2 meningitis: a retrospective study of 40 patients. Scand J Infect Dis. 2002;34(4):278\u201383.","journal-title":"Scand J Infect Dis"},{"issue":"3","key":"907_CR13","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1093\/infdis\/170.3.678","volume":"170","author":"E Aurelius","year":"1994","unstructured":"Aurelius E, et al. Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis. J Infect Dis. 1994;170(3):678\u201381.","journal-title":"J Infect Dis"},{"issue":"2","key":"907_CR14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3109\/00365549409011777","volume":"26","author":"M Glimaker","year":"1994","unstructured":"Glimaker M, Olcen P, Andersson B. Interferon-gamma in cerebrospinal fluid from patients with viral and bacterial meningitis. Scand J Infect Dis. 1994;26(2):141\u20137.","journal-title":"Scand J Infect Dis"},{"issue":"4","key":"907_CR15","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1128\/CVI.00333-10","volume":"18","author":"E Franzen-Rohl","year":"2011","unstructured":"Franzen-Rohl E, et al. Increased cell-mediated immune responses in patients with recurrent herpes simplex virus type 2 meningitis. Clin Vaccine Immunol. 2011;18(4):655\u201360.","journal-title":"Clin Vaccine Immunol"},{"issue":"8405","key":"907_CR16","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0140-6736(84)92623-0","volume":"2","author":"B Skoldenberg","year":"1984","unstructured":"Skoldenberg B, et al. Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients. Lancet. 1984;2(8405):707\u201311.","journal-title":"Lancet"},{"issue":"2","key":"907_CR17","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s40265-013-0007-5","volume":"73","author":"M Studahl","year":"2013","unstructured":"Studahl M, et al. Acute viral infections of the central nervous system in immunocompetent adults: diagnosis and management. Drugs. 2013;73(2):131\u201358.","journal-title":"Drugs"},{"issue":"4","key":"907_CR18","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0166-3542(81)90011-5","volume":"1","author":"D Brigden","year":"1981","unstructured":"Brigden D, et al. Acyclovir\u2014a review of the preclinical and early clinical data of a new antiherpes drug. Antiviral Res. 1981;1(4):203\u201312.","journal-title":"Antiviral Res"},{"issue":"3","key":"907_CR19","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/nri3391","volume":"13","author":"R Shechter","year":"2013","unstructured":"Shechter R, London A, Schwartz M. Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates. Nat Rev Immunol. 2013;13(3):206\u201318.","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"907_CR20","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2045-8118-8-4","volume":"8","author":"B Engelhardt","year":"2011","unstructured":"Engelhardt B, Coisne C. Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle. Fluids Barriers CNS. 2011;8(1):4.","journal-title":"Fluids Barriers CNS"},{"issue":"9","key":"907_CR21","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nri3265","volume":"12","author":"RM Ransohoff","year":"2012","unstructured":"Ransohoff RM, Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol. 2012;12(9):623\u201335.","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"907_CR22","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1124\/pr.57.2.4","volume":"57","author":"BT Hawkins","year":"2005","unstructured":"Hawkins BT, Davis TP. The blood-brain barrier\/neurovascular unit in health and disease. Pharmacol Rev. 2005;57(2):173\u201385.","journal-title":"Pharmacol Rev"},{"issue":"1-2","key":"907_CR23","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jneuroim.2008.04.022","volume":"198","author":"S Melik-Parsadaniantz","year":"2008","unstructured":"Melik-Parsadaniantz S, Rostene W. Chemokines and neuromodulation. J Neuroimmunol. 2008;198(1-2):62\u20138.","journal-title":"J Neuroimmunol"},{"key":"907_CR24","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1146\/annurev-immunol-032713-120145","volume":"32","author":"JW Griffith","year":"2014","unstructured":"Griffith JW, Sokol CL, Luster AD. Chemokines and chemokine receptors: positioning cells for host defense and immunity. Annu Rev Immunol. 2014;32:659\u2013702.","journal-title":"Annu Rev Immunol"},{"issue":"5","key":"907_CR25","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1365-2990.2010.01089.x","volume":"36","author":"M Muller","year":"2010","unstructured":"Muller M, et al. Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrum. Neuropathol Appl Neurobiol. 2010;36(5):368\u201387.","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"2","key":"907_CR26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/icb.2010.158","volume":"89","author":"JR Groom","year":"2011","unstructured":"Groom JR, Luster AD. CXCR3 ligands: redundant, collaborative and antagonistic functions. Immunol Cell Biol. 2011;89(2):207\u201315.","journal-title":"Immunol Cell Biol"},{"issue":"11","key":"907_CR27","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1038\/labinvest.3700155","volume":"84","author":"SR McColl","year":"2004","unstructured":"McColl SR, et al. Expression of rat I-TAC\/CXCL11\/SCYA11 during central nervous system inflammation: comparison with other CXCR3 ligands. Lab Invest. 2004;84(11):1418\u201329.","journal-title":"Lab Invest"},{"issue":"5","key":"907_CR28","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1128\/JCM.43.5.2058-2064.2005","volume":"43","author":"L Namvar","year":"2005","unstructured":"Namvar L, et al. Detection and typing of Herpes Simplex virus (HSV) in mucocutaneous samples by TaqMan PCR targeting a gB segment homologous for HSV types 1 and 2. J Clin Microbiol. 2005;43(5):2058\u201364.","journal-title":"J Clin Microbiol"},{"issue":"1-2","key":"907_CR29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.clinbiochem.2013.11.010","volume":"47","author":"D Bremell","year":"2014","unstructured":"Bremell D, et al. Automated cerebrospinal fluid cell count\u2014new reference ranges and evaluation of its clinical use in central nervous system infections. Clin Biochem. 2014;47(1-2):25\u201330.","journal-title":"Clin Biochem"},{"issue":"3","key":"907_CR30","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1189\/jlb.1102577","volume":"74","author":"J Melchjorsen","year":"2003","unstructured":"Melchjorsen J, Sorensen LN, Paludan SR. Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function. J Leukoc Biol. 2003;74(3):331\u201343.","journal-title":"J Leukoc Biol"},{"issue":"3","key":"907_CR31","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s13365-011-0034-5","volume":"17","author":"RB Meeker","year":"2011","unstructured":"Meeker RB, et al. Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection. J Neurovirol. 2011;17(3):258\u201373.","journal-title":"J Neurovirol"},{"issue":"5","key":"907_CR32","doi-asserted-by":"crossref","first-page":"390","DOI":"10.4161\/cam.21054","volume":"6","author":"RB Meeker","year":"2012","unstructured":"Meeker RB, et al. Cell trafficking through the choroid plexus. Cell Adh Migr. 2012;6(5):390\u20136.","journal-title":"Cell Adh Migr"},{"issue":"10","key":"907_CR33","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1172\/JCI19188","volume":"112","author":"JC Lo","year":"2003","unstructured":"Lo JC, et al. Differential regulation of CCL21 in lymphoid\/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. J Clin Invest. 2003;112(10):1495\u2013505.","journal-title":"J Clin Invest"},{"issue":"4","key":"907_CR34","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S1286-4579(02)01560-5","volume":"4","author":"H Lue","year":"2002","unstructured":"Lue H, et al. Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. Microbes Infect. 2002;4(4):449\u201360.","journal-title":"Microbes Infect"},{"issue":"8","key":"907_CR35","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/nn.3161","volume":"15","author":"SS Ousman","year":"2012","unstructured":"Ousman SS, Kubes P. Immune surveillance in the central nervous system. Nat Neurosci. 2012;15(8):1096\u2013101.","journal-title":"Nat Neurosci"},{"issue":"1","key":"907_CR36","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0022-510X(98)00061-6","volume":"157","author":"A Rosler","year":"1998","unstructured":"Rosler A, et al. Time course of chemokines in the cerebrospinal fluid and serum during herpes simplex type 1 encephalitis. J Neurol Sci. 1998;157(1):82\u20139.","journal-title":"J Neurol Sci"},{"key":"907_CR37","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3389\/fncel.2014.00264","volume":"8","author":"D Michlmayr","year":"2014","unstructured":"Michlmayr D, Lim JK. Chemokine receptors as important regulators of pathogenesis during arboviral encephalitis. Front Cell Neurosci. 2014;8:264.","journal-title":"Front Cell Neurosci"},{"key":"907_CR38","volume-title":"Central Nervous System Diseases and Inflammation","author":"MJ Hickey","year":"2008","unstructured":"Hickey MJ, et al. The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System. In: Lane TE, editor. Central Nervous System Diseases and Inflammation. New York: Springer; 2008."},{"key":"907_CR39","first-page":"1","volume":"6","author":"D Michlmayr","year":"2014","unstructured":"Michlmayr D, McKimmie CS. Role of CXCL10 in central nervous system inflammation. Int J Interferon Cytokine Mediat Res. 2014;6:1\u201318.","journal-title":"Int J Interferon Cytokine Mediat Res"},{"issue":"2","key":"907_CR40","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.4049\/jimmunol.180.2.1098","volume":"180","author":"M Thapa","year":"2008","unstructured":"Thapa M, et al. CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system. J Immunol. 2008;180(2):1098\u2013106.","journal-title":"J Immunol"},{"issue":"18","key":"907_CR41","doi-asserted-by":"crossref","first-page":"9486","DOI":"10.1128\/JVI.00854-09","volume":"83","author":"M Thapa","year":"2009","unstructured":"Thapa M, Carr DJ. CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration. J Virol. 2009;83(18):9486\u2013501.","journal-title":"J Virol"},{"key":"907_CR42","doi-asserted-by":"crossref","unstructured":"Zimmermann J, et al. Enhanced viral clearance and reduced leukocyte infiltration in experimental herpes encephalitis after intranasal infection of CXCR3-deficient mice. J Neurovirol. 2017;23(3):394\u2013403.","DOI":"10.1007\/s13365-016-0508-6"},{"issue":"9","key":"907_CR43","doi-asserted-by":"crossref","first-page":"4162","DOI":"10.1167\/iovs.07-0261","volume":"48","author":"P Lundberg","year":"2007","unstructured":"Lundberg P, et al. Effects of CXCR3 signaling on development of fatal encephalitis and corneal and periocular skin disease in HSV-infected mice are mouse-strain dependent. Invest Ophthalmol Vis Sci. 2007;48(9):4162\u201370.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"907_CR44","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1172\/JCI71951","volume":"124","author":"Y Zohar","year":"2014","unstructured":"Zohar Y, et al. CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis. J Clin Invest. 2014;124(5):2009\u201322.","journal-title":"J Clin Invest"},{"issue":"7","key":"907_CR45","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/s00415-005-0752-9","volume":"252","author":"TA Rupprecht","year":"2005","unstructured":"Rupprecht TA, et al. CXCL11 is involved in leucocyte recruitment to the central nervous system in neuroborreliosis. J Neurol. 2005;252(7):820\u20133.","journal-title":"J Neurol"},{"issue":"6","key":"907_CR46","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.ejpn.2011.05.008","volume":"15","author":"A Cavcic","year":"2011","unstructured":"Cavcic A, et al. Concentration gradient of CXCL10 and CXCL11 between the cerebrospinal fluid and plasma in children with enteroviral aseptic meningitis. Eur J Paediatr Neurol. 2011;15(6):502\u20137.","journal-title":"Eur J Paediatr Neurol"},{"issue":"1","key":"907_CR47","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/jlb.59.1.67","volume":"59","author":"P Proost","year":"1996","unstructured":"Proost P, Wuyts A, Van Damme J. Human monocyte chemotactic proteins-2 and -3: structural and functional comparison with MCP-1. J Leukoc Biol. 1996;59(1):67\u201374.","journal-title":"J Leukoc Biol"},{"issue":"1-2","key":"907_CR48","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jneuroim.2005.03.009","volume":"164","author":"S Kastenbauer","year":"2005","unstructured":"Kastenbauer S, et al. Patterns of protein expression in infectious meningitis: a cerebrospinal fluid protein array analysis. J Neuroimmunol. 2005;164(1-2):134\u20139.","journal-title":"J Neuroimmunol"},{"key":"907_CR49","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bbacli.2014.06.001","volume":"1","author":"MM Koopmans","year":"2014","unstructured":"Koopmans MM, et al. Cerebrospinal fluid inflammatory markers in patients with meningitis. BBA Clin. 2014;1:44\u201351.","journal-title":"BBA Clin"},{"key":"907_CR50","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1146\/annurev.immunol.21.120601.140942","volume":"21","author":"SJ Szabo","year":"2003","unstructured":"Szabo SJ, et al. Molecular mechanisms regulating Th1 immune responses. Annu Rev Immunol. 2003;21:713\u201358.","journal-title":"Annu Rev Immunol"},{"issue":"9","key":"907_CR51","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0161-5890(02)00210-9","volume":"39","author":"S Diehl","year":"2002","unstructured":"Diehl S, Rincon M. The two faces of IL-6 on Th1\/Th2 differentiation. Mol Immunol. 2002;39(9):531\u20136.","journal-title":"Mol Immunol"},{"issue":"3","key":"907_CR52","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/jcbfm.2009.240","volume":"30","author":"BD Semple","year":"2010","unstructured":"Semple BD, Kossmann T, Morganti-Kossmann MC. Role of chemokines in CNS health and pathology: a focus on the CCL2\/CCR2 and CXCL8\/CXCR2 networks. J Cereb Blood Flow Metab. 2010;30(3):459\u201373.","journal-title":"J Cereb Blood Flow Metab"}],"container-title":["Journal of Neuroinflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12974-017-0907-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,29]],"date-time":"2019-09-29T04:11:57Z","timestamp":1569730317000},"score":1,"resource":{"primary":{"URL":"http:\/\/jneuroinflammation.biomedcentral.com\/articles\/10.1186\/s12974-017-0907-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,10]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["907"],"URL":"https:\/\/doi.org\/10.1186\/s12974-017-0907-5","relation":{},"ISSN":["1742-2094"],"issn-type":[{"value":"1742-2094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,10]]},"article-number":"134"}}