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Detailed records of all experimental procedures, animal health monitoring, and any protocol deviations were meticulously maintained and regularly reviewed to ensure compliance with approved standards. The animal research protocol employed in this study fully conformed to the ethical and procedural standards established by the Korea Association for Laboratory Animal Science (KALAS), a nationally recognized authority on laboratory animal welfare. Furthermore, all experimental procedures involving potential biohazards were reviewed and approved by the Institutional Biosafety Committee (IBC) of Jeonbuk National University, thereby ensuring compliance with all relevant biosafety regulations and institutional policies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consents for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"259"}}