{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T23:24:04Z","timestamp":1787268244661,"version":"build-2736575974"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":67,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["NS140036"],"award-info":[{"award-number":["NS140036"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["NS137812"],"award-info":[{"award-number":["NS137812"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["NS105584"],"award-info":[{"award-number":["NS105584"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007865","name":"University of Texas Medical Branch","doi-asserted-by":"publisher","award":["Start package"],"award-info":[{"award-number":["Start package"]}],"id":[{"id":"10.13039\/100007865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007865","name":"University of Texas Medical Branch","doi-asserted-by":"publisher","award":["Start Package"],"award-info":[{"award-number":["Start Package"]}],"id":[{"id":"10.13039\/100007865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH128082"],"award-info":[{"award-number":["MH128082"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neuroinflammation"],"DOI":"10.1186\/s12974-026-03901-4","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T03:06:06Z","timestamp":1781492766000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nipah virus infects the brain and triggers neuronal and glial damage in a hamster model"],"prefix":"10.1186","volume":"23","author":[{"given":"Karl","family":"Valerdi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Paroha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Littlefield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Plante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Plante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Valdebenito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junki","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliseo","family":"Eugenin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"issue":"7","key":"3901_CR1","doi-asserted-by":"publisher","first-page":"102782","DOI":"10.1016\/j.jiph.2025.102782","volume":"18","author":"RR Sahay","year":"2025","unstructured":"Sahay RR, et al. Encephalitis-predominant Nipah virus outbreaks in Kerala, India during 2024. J Infect Public Health. 2025;18(7):102782.","journal-title":"J Infect Public Health"},{"issue":"1","key":"3901_CR2","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1007\/s00253-025-13474-6","volume":"109","author":"R Madhukalya","year":"2025","unstructured":"Madhukalya R, et al. Nipah virus: pathogenesis, genome, diagnosis, and treatment. Appl Microbiol Biotechnol. 2025;109(1):158.","journal-title":"Appl Microbiol Biotechnol"},{"key":"3901_CR3","doi-asserted-by":"publisher","first-page":"100527","DOI":"10.1016\/j.lansea.2024.100527","volume":"33","author":"MZ Hassan","year":"2025","unstructured":"Hassan MZ, et al. Improving clinical care of patients in Nipah outbreaks: moving beyond \u2018compassionate use\u2019. Lancet Reg Health Southeast Asia. 2025;33:100527.","journal-title":"Lancet Reg Health Southeast Asia"},{"issue":"1","key":"3901_CR4","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1186\/s12985-025-02728-4","volume":"22","author":"A Ganguly","year":"2025","unstructured":"Ganguly A, et al. The rising threat of Nipah virus: a highly contagious and deadly zoonotic pathogen. Virol J. 2025;22(1):139.","journal-title":"Virol J"},{"issue":"3","key":"3901_CR5","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/j.1365-2990.2008.00991.x","volume":"35","author":"KT Wong","year":"2009","unstructured":"Wong KT, et al. Human Hendra virus infection causes acute and relapsing encephalitis. Neuropathol Appl Neurobiol. 2009;35(3):296\u2013305.","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"5","key":"3901_CR6","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1111\/bpa.12278","volume":"25","author":"KC Ong","year":"2015","unstructured":"Ong KC, Wong KT. Henipavirus Encephalitis: Recent Developments and Advances. Brain Pathol. 2015;25(5):605\u201313.","journal-title":"Brain Pathol"},{"key":"3901_CR7","doi-asserted-by":"publisher","first-page":"101719","DOI":"10.1016\/j.nmni.2026.101719","volume":"70","author":"KSP Cabuhat","year":"2026","unstructured":"Cabuhat KSP, et al. Recurrent Nipah virus infections: Implications for preparedness and public health response. New Microbes New Infect. 2026;70:101719.","journal-title":"New Microbes New Infect"},{"issue":"6","key":"3901_CR8","doi-asserted-by":"publisher","first-page":"e12828","DOI":"10.1111\/nan.12828","volume":"48","author":"KC Ong","year":"2022","unstructured":"Ong KC, et al. Neuronal infection is a major pathogenetic mechanism and cause of fatalities in human acute Nipah virus encephalitis. Neuropathol Appl Neurobiol. 2022;48(6):e12828.","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"1","key":"3901_CR9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3988\/jcn.2023.0240","volume":"20","author":"KA Kvam","year":"2024","unstructured":"Kvam KA, et al. Outcome and Sequelae of Infectious Encephalitis. J Clin Neurol. 2024;20(1):23\u201336.","journal-title":"J Clin Neurol"},{"issue":"3","key":"3901_CR10","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1002\/ana.21178","volume":"62","author":"JJ Sejvar","year":"2007","unstructured":"Sejvar JJ, et al. Long-term neurological and functional outcome in Nipah virus infection. Ann Neurol. 2007;62(3):235\u201342.","journal-title":"Ann Neurol"},{"issue":"1","key":"3901_CR11","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1093\/infdis\/jiae300","volume":"231","author":"K Goldin","year":"2025","unstructured":"Goldin K, et al. Nipah Virus-Associated Neuropathology in African Green Monkeys During Acute Disease and Convalescence. J Infect Dis. 2025;231(1):219\u201329.","journal-title":"J Infect Dis"},{"issue":"10","key":"3901_CR12","doi-asserted-by":"publisher","first-page":"e0012635","DOI":"10.1371\/journal.pntd.0012635","volume":"18","author":"M Singh","year":"2024","unstructured":"Singh M, et al. Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters. PLoS Negl Trop Dis. 2024;18(10):e0012635.","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"3901_CR13","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1002\/path.4444","volume":"235","author":"E de Wit","year":"2015","unstructured":"de Wit E, Munster VJ. Animal models of disease shed light on Nipah virus pathogenesis and transmission. J Pathol. 2015;235(2):196\u2013205.","journal-title":"J Pathol"},{"issue":"1","key":"3901_CR14","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1177\/0300985814556189","volume":"52","author":"L Baseler","year":"2015","unstructured":"Baseler L, et al. Syrian hamsters (Mesocricetus auratus) oronasally inoculated with a Nipah virus isolate from Bangladesh or Malaysia develop similar respiratory tract lesions. Vet Pathol. 2015;52(1):38\u201345.","journal-title":"Vet Pathol"},{"issue":"4","key":"3901_CR15","doi-asserted-by":"publisher","first-page":"308","DOI":"10.3855\/jidc.3648","volume":"7","author":"O Escaffre","year":"2013","unstructured":"Escaffre O, Borisevich V, Rockx B. Pathogenesis of Hendra and Nipah virus infection in humans. J Infect Dev Ctries. 2013;7(4):308\u201311.","journal-title":"J Infect Dev Ctries"},{"issue":"6","key":"3901_CR16","doi-asserted-by":"publisher","first-page":"3284","DOI":"10.1128\/JVI.02576-12","volume":"87","author":"O Escaffre","year":"2013","unstructured":"Escaffre O, et al. Henipavirus pathogenesis in human respiratory epithelial cells. J Virol. 2013;87(6):3284\u201394.","journal-title":"J Virol"},{"issue":"4","key":"3901_CR17","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1354\/vp.45-4-576","volume":"45","author":"FJ Torres-Velez","year":"2008","unstructured":"Torres-Velez FJ, et al. Histopathologic and immunohistochemical characterization of Nipah virus infection in the guinea pig. Vet Pathol. 2008;45(4):576\u201385.","journal-title":"Vet Pathol"},{"issue":"12","key":"3901_CR18","doi-asserted-by":"publisher","first-page":"7528","DOI":"10.1128\/JVI.79.12.7528-7534.2005","volume":"79","author":"H Weingartl","year":"2005","unstructured":"Weingartl H, et al. Invasion of the central nervous system in a porcine host by nipah virus. J Virol. 2005;79(12):7528\u201334.","journal-title":"J Virol"},{"issue":"3","key":"3901_CR19","first-page":"167","volume":"72","author":"CE Rella","year":"2014","unstructured":"Rella CE, Ruel N, Eugenin EA. Development of imaging techniques to study the pathogenesis of biosafety level 2\/3 infectious agents. Pathog Dis. 2014;72(3):167\u201373.","journal-title":"Pathog Dis"},{"key":"3901_CR20","doi-asserted-by":"crossref","unstructured":"Scotto G, et al. Nipah virus encephalitis: pathogenetic aspects and current therapeutic strategies. Pathogens. 2026;15(4):1\u201314.","DOI":"10.3390\/pathogens15040443"},{"key":"3901_CR21","doi-asserted-by":"publisher","first-page":"1708412","DOI":"10.3389\/fvets.2025.1708412","volume":"12","author":"K Swan","year":"2025","unstructured":"Swan K, et al. Histopathological and immunohistochemical characterization of lesions in the golden Syrian hamster model of Nipah virus infection (Bangladesh strain). Front Vet Sci. 2025;12:1708412.","journal-title":"Front Vet Sci"},{"key":"3901_CR22","doi-asserted-by":"publisher","first-page":"1518358","DOI":"10.3389\/fvets.2025.1518358","volume":"12","author":"I Ruedas-Torres","year":"2025","unstructured":"Ruedas-Torres I, et al. Pathology and host-pathogen interactions in a golden Syrian hamster model of Nipah virus infection. Front Vet Sci. 2025;12:1518358.","journal-title":"Front Vet Sci"},{"issue":"5","key":"3901_CR23","doi-asserted-by":"publisher","first-page":"90","DOI":"10.31083\/j.jin2305090","volume":"23","author":"MMJ Al-Obaidi","year":"2024","unstructured":"Al-Obaidi MMJ, Muthanna A, Desa MNM. Nipah Virus Neurotropism: Insights into Blood-Brain Barrier Disruption. J Integr Neurosci. 2024;23(5):90.","journal-title":"J Integr Neurosci"},{"key":"3901_CR24","doi-asserted-by":"crossref","unstructured":"Donoso M et al. Identification, Quantification, and Characterization of HIV-1 Reservoirs in the Human Brain. Cells. 2022;11(15).","DOI":"10.3390\/cells11152379"},{"key":"3901_CR25","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/978-1-4939-3046-3_18","volume":"1354","author":"EA Eugenin","year":"2016","unstructured":"Eugenin EA, Berman JW. Improved Methods to Detect Low Levels of HIV Using Antibody-Based Technologies. Methods Mol Biol. 2016;1354:265\u201379.","journal-title":"Methods Mol Biol"},{"issue":"3","key":"3901_CR26","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1097\/WCO.0000000000000097","volume":"27","author":"JP Stahl","year":"2014","unstructured":"Stahl JP, Mailles A. What is new about epidemiology of acute infectious encephalitis? Curr Opin Neurol. 2014;27(3):337\u201341.","journal-title":"Curr Opin Neurol"},{"issue":"1","key":"3901_CR27","doi-asserted-by":"publisher","first-page":"3712","DOI":"10.1038\/s41598-025-33750-9","volume":"16","author":"KA Davies","year":"2025","unstructured":"Davies KA, et al. Inactivation of Ebola, Nipah, and Lassa viruses in tissue using neutral buffered formalin, MagMAX lysis\/binding solution, or TriPure isolation reagent. Sci Rep. 2025;16(1):3712.","journal-title":"Sci Rep"},{"key":"3901_CR28","doi-asserted-by":"crossref","unstructured":"Watson ZT, et al. Differential selectivity of microglia and astrocytes in HIV-1 gp120-induced synaptic pruning. Brain. 2025. AWAF429:1\u201317.","DOI":"10.1093\/brain\/awaf429"},{"issue":"2","key":"3901_CR29","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.neuron.2017.03.046","volume":"94","author":"LF Gumy","year":"2017","unstructured":"Gumy LF, et al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017;94(2):347\u2013e3627.","journal-title":"Neuron"},{"issue":"3","key":"3901_CR30","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1038\/s41582-021-00616-3","volume":"18","author":"A Abdelhak","year":"2022","unstructured":"Abdelhak A, et al. Blood GFAP as an emerging biomarker in brain and spinal cord disorders. Nat Rev Neurol. 2022;18(3):158\u201372.","journal-title":"Nat Rev Neurol"},{"key":"3901_CR31","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.matbio.2025.02.005","volume":"137","author":"A Nasrollahi","year":"2025","unstructured":"Nasrollahi A, Yao Y. Laminins and the blood-brain barrier. Matrix Biol. 2025;137:33\u201341.","journal-title":"Matrix Biol"},{"issue":"1","key":"3901_CR32","doi-asserted-by":"publisher","first-page":"2613510","DOI":"10.1080\/22221751.2026.2613510","volume":"15","author":"WR Aquib","year":"2026","unstructured":"Aquib WR, et al. Post-mortem surveillance: an innovative strategy to detect and prevent spread of Nipah virus infection in humans. Emerg Microbes Infect. 2026;15(1):2613510.","journal-title":"Emerg Microbes Infect"},{"issue":"17","key":"3901_CR33","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1056\/NEJM200004273421701","volume":"342","author":"KJ Goh","year":"2000","unstructured":"Goh KJ, et al. Clinical features of Nipah virus encephalitis among pig farmers in Malaysia. N Engl J Med. 2000;342(17):1229\u201335.","journal-title":"N Engl J Med"},{"issue":"5470","key":"3901_CR34","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1126\/science.288.5470.1432","volume":"288","author":"KB Chua","year":"2000","unstructured":"Chua KB, et al. Nipah virus: a recently emergent deadly paramyxovirus. Science. 2000;288(5470):1432\u20135.","journal-title":"Science"},{"issue":"9186","key":"3901_CR35","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/S0140-6736(99)04299-3","volume":"354","author":"KB Chua","year":"1999","unstructured":"Chua KB, et al. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia. Lancet. 1999;354(9186):1257\u20139.","journal-title":"Lancet"},{"issue":"4","key":"3901_CR36","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1176\/jnp.16.4.500","volume":"16","author":"BY Ng","year":"2004","unstructured":"Ng BY, et al. Neuropsychiatric sequelae of Nipah virus encephalitis. J Neuropsychiatry Clin Neurosci. 2004;16(4):500\u20134.","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"15","key":"3901_CR37","doi-asserted-by":"publisher","first-page":"7658","DOI":"10.1128\/JVI.00473-11","volume":"85","author":"B Rockx","year":"2011","unstructured":"Rockx B, et al. Clinical outcome of henipavirus infection in hamsters is determined by the route and dose of infection. J Virol. 2011;85(15):7658\u201371.","journal-title":"J Virol"},{"key":"3901_CR38","doi-asserted-by":"crossref","unstructured":"Liu J et al. Nipah virus persists in the brains of nonhuman primate survivors. JCI Insight. 2019;4(14).","DOI":"10.1172\/jci.insight.129629"},{"issue":"1","key":"3901_CR39","doi-asserted-by":"publisher","first-page":"2224642","DOI":"10.1080\/21505594.2023.2224642","volume":"14","author":"S Mohandas","year":"2023","unstructured":"Mohandas S, et al. Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate). Virulence. 2023;14(1):2224642.","journal-title":"Virulence"},{"issue":"10","key":"3901_CR40","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1001\/jamaneurol.2017.1874","volume":"74","author":"LY Leung","year":"2017","unstructured":"Leung LY, Melkumova E, Thaler DE. Longitudinal Care for Young Adults With Stroke. JAMA Neurol. 2017;74(10):1163\u20134.","journal-title":"JAMA Neurol"},{"issue":"1","key":"3901_CR41","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/jcbfm.2015.68","volume":"36","author":"A Vilar-Bergua","year":"2016","unstructured":"Vilar-Bergua A, et al. Blood and CSF biomarkers in brain subcortical ischemic vascular disease: Involved pathways and clinical applicability. J Cereb Blood Flow Metab. 2016;36(1):55\u201371.","journal-title":"J Cereb Blood Flow Metab"},{"key":"3901_CR42","doi-asserted-by":"publisher","first-page":"1567719","DOI":"10.3389\/fped.2025.1567719","volume":"13","author":"BP Arruda","year":"2025","unstructured":"Arruda BP, et al. Perinatal asphyxia and Alzheimer\u2019s disease: is there a correlation? Front Pediatr. 2025;13:1567719.","journal-title":"Front Pediatr"},{"issue":"10","key":"3901_CR43","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1007\/s00018-022-04536-3","volume":"79","author":"C Li","year":"2022","unstructured":"Li C, et al. The heterogeneity of microglial activation and its epigenetic and non-coding RNA regulations in the immunopathogenesis of neurodegenerative diseases. Cell Mol Life Sci. 2022;79(10):511.","journal-title":"Cell Mol Life Sci"},{"issue":"4","key":"3901_CR44","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1007\/s11011-022-00953-2","volume":"37","author":"RAL De Sousa","year":"2022","unstructured":"De Sousa RAL. Reactive gliosis in Alzheimer\u2019s disease: a crucial role for cognitive impairment and memory loss. Metab Brain Dis. 2022;37(4):851\u20137.","journal-title":"Metab Brain Dis"},{"key":"3901_CR45","doi-asserted-by":"crossref","unstructured":"Ghasemi M, Keyhanian K, Douthwright C. Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Cells. 2021;10(2).","DOI":"10.3390\/cells10020249"},{"key":"3901_CR46","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3389\/fncel.2018.00193","volume":"12","author":"CY Liu","year":"2018","unstructured":"Liu CY, et al. Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer\u2019s Disease. Front Cell Neurosci. 2018;12:193.","journal-title":"Front Cell Neurosci"}],"container-title":["Journal of Neuroinflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12974-026-03901-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12974-026-03901-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12974-026-03901-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T22:33:09Z","timestamp":1787265189000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12974-026-03901-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["3901"],"URL":"https:\/\/doi.org\/10.1186\/s12974-026-03901-4","relation":{},"ISSN":["1742-2094"],"issn-type":[{"value":"1742-2094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]},"assertion":[{"value":"16 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"281"}}