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Written informed consent was obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"RK reports that she is an employee at ARTPred B.V. during her PhD at Erasmus MC.PHMS reports that he is a co-owner of IS-Diagnostics Ltd. and he has a patent MICROBIAL POPULATION ANALYSIS (9506109) licensed to ARTPred B.V., a patent MICROBIAL POPULATION ANALYSIS (20170159108) licensed to ARTPred.SAM has a 100% University appointment is co-owner of IS-diagnostics Ltd., (a spin-off company inside the VU University Medical center Amsterdam, NL), which is the company that developed the IS-pro technique.JDdJ reports personal fees from ARTPred B.V., grants from NGI Pre-Seed, other from RedMedTech Discovery Fund, from STW Valorisation grant 1, other from Take-off early phase trajectory, grants from Innovatie Prestatie Contract, other from Microbiome Ltd., grants from MIT Haalbaarheid, grants from EUROSTARS, other from Dutch R&D tax credit (WBSO), other from Erasmus MC, during the conduct of the study; personal fees and other from ARTPred B.V., outside the submitted work; In addition, Dr. de Jonge has a patent New method and kit for prediction success of in vitro fertilization licensed to ARTPred, a patent MICROBIAL POPULATION ANALYSIS (9506109) licensed to ARTPred, a patent MICROBIAL POPULATION ANALYSIS (20170159108) licensed to ARTPred, a patent METHOD AND KIT FOR PREDICTING THE OUTCOME OF AN ASSISTED\u00d0EPRODUCTIVE TECHNOLOGY PROCEDURE pending to ARTPred and a patent METHOD AND KIT FOR ALTERING THE OUTCOME OF AN ASSISTED REPRODUCTIVE TECHNOLOGY PROCEDURE pending to ARTPred.LP reports other from IS-Diagnostics Ltd., during the conduct of the study; other from IS-Diagnostics Ltd., outside the submitted work.WJSSC received personal consultancy and educational fees from Goodlife Fertility B.V. His employer has in collaboration with ARTPred acquired a MIND subsidy to cover part of the costs of this collaboration project.AEB reports that he is a co-owner of IS-Diagnostics Ltd. In addition, Dr. Budding has a patent 392EPP0 pending, has a patent MICROBIAL POPULATION ANALYSIS (9506109) licensed to ARTPred, a patent MICROBIAL POPULATION ANALYSIS (20170159108) licensed to ARTPred, a patent METHOD AND KIT FOR PREDICTING THE OUTCOME OF AN ASSISTED\u00d0EPRODUCTIVE TECHNOLOGY PROCEDURE pending to ARTPred and a patent METHOD AND KIT FOR ALTERING THE OUTCOME OF AN ASSISTED REPRODUCTIVE TECHNOLOGY PROCEDURE pending to ARTPred.JSEL reports grants from Dutch Heart Foundation, Ferring, Metagenics Inc.. He received personal consultancy fees from ARTPred B.V., Danone, Euroscreen, Roche, during the conduct of the study. In addition, JSEL is a co applicant on a Erasmus MC patent (New method and kit for prediction success of in vitro fertilization), that predicts IVF outcome based on the urinary microbiome. This particular patent is licensed to ARTPred B.V.The other authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"202"}}