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Therefore, given the multidimensionality of this disorder and the need to pay more attention to all biological, psychological and social dimensions in its treatment, the present study was conducted to investigate the bio-psychological factors contributing to vaginismus.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This descriptive cross-sectional study was conducted on 180 Iranian women with vaginismus who had been referred to sexual health clinics of Tehran province in 2020. Multistage random sampling method was used in this study, and vaginismus was diagnosed in women by a specialist through using a questionnaire. Data collection tools included demographic and obstetric information form, valid and reliable Sexual Function Questionnaire, Depression Anxiety Stress Scales (DASS), Sex Fear Questionnaire, Vaginal Penetration Cognition Questionnaire, Sexual Self-Efficacy Scale, Sexual Knowledge and Attitude Scale, Sexual Quality of Life-Female, Inventory of Sexual Satisfaction, ENRICH Marital Satisfaction Scale, Sexual Intimacy Scale and Questionnaire for Diagnosis of Vaginismus. In order to determine the factors related to vaginismus, multiple linear regression model was used through SPSS software version 25 (SPSS Inc., Chicago, IL).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Based on the results of the present study, the mean age of women and the mean duration of their marriage were 27.77\u2009\u00b1\u20095.36 and 4.07\u2009\u00b1\u20093.87\u00a0years respectively. As the results of multiple linear regression revealed, the variables of fear of sex (B\u2009=\u20090.141, P\u2009=\u20090.036), positive cognition (B\u2009=\u20090.197, P\u2009=\u20090.046), self-image (B\u2009=\u20090.651, P\u2009=\u20090.001), sexual intimacy (B\u2009=\u2009-0.116, P\u2009=\u20090.021), quality of sexual life (B\u2009=\u20090.115, P\u2009=\u20090.002) and education (B\u2009=\u20092.129, P\u2009=\u20090.024) from the bio-psychosocial model were the final predictors of vaginismus diagnosis score in women with this disorder. According to the results of multiple linear regression, 45.5% of the variance of vaginismus diagnosis total score was explained by these variables (R\u2009=\u20090.706, R2\u2009=\u20090.498 and ADJ.R2\u2009=\u20090.455).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The results of the present study showed that the variables of fear of sex, positive cognition and negative self-image, sexual intimacy, quality of sexual life and education were the final predictors of vaginismus diagnosis score. This disorder is, thus, considered to be multidimensional.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12978-021-01260-2","type":"journal-article","created":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T23:02:29Z","timestamp":1634598149000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Bio-psychosocial factor of vaginismus in Iranian women"],"prefix":"10.1186","volume":"18","author":[{"given":"Mojdeh","family":"Banaei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nourossadat","family":"Kariman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giti","family":"Ozgoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maliheh","family":"Nasiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"issue":"1","key":"1260_CR1","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1002\/ijgo.13523","volume":"153","author":"M Banaei","year":"2021","unstructured":"Banaei M, et al. 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