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However, due to confounding factors, the accuracy and uniformity of published findings on IVF outcomes have been disputed. This study aimed to assess the effects of both male and female body mass index (BMI), individually and in combination, on IVF outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This retrospective cohort study included 11,191 couples undergoing IVF. Per the Chinese BMI standard, the couples were divided into four groups: normal; female overweight\/obesity; male overweight\/obesity; and combined male and female overweight\/obesity. The IVF outcomes of the four groups were compared and analysed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Regarding the 6569 first fresh IVF-ET cycles, compared with the normal weight group, the female overweight\/obesity and combined male\/female overweight\/obesity groups had much lower numbers of available embryos and high-quality embryos (p\u2009&lt;\u20090.05); additionally, the fertilization (p\u2009&lt;\u20090.001) and normal fertilization rates (p\u2009&lt;\u20090.001) were significantly decreased in the female overweight\/obesity group. The combined male\/female overweight\/obesity group had significant reductions in the available embryo (p\u2009=\u20090.002), high-quality embryo (p\u2009=\u20090.010), fertilization (p\u2009=\u20090.001) and normal fertilization rates (p\u2009&lt;\u20090.001); however, neither male or female overweight\/obesity nor their combination significantly affected the clinical pregnancy rate (CPR), live birth rate (LBR) or abortion rate (p\u2009&gt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Our findings support the notion that overweight\/obesity does not influence pregnancy success; however, we found that overweight\/obesity affects the fertilization rate and embryo number and that there are sex differences.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12978-022-01558-9","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T11:13:37Z","timestamp":1672658017000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The influence of male and female overweight\/obesity on IVF outcomes: a cohort study based on registration in Western China"],"prefix":"10.1186","volume":"20","author":[{"given":"Xiang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjia","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junping","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie","family":"Chong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,2]]},"reference":[{"key":"1558_CR1","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1007\/s11695-011-0490-2","volume":"21","author":"O Kaidar-Person","year":"2011","unstructured":"Kaidar-Person O, Bar-Sela G, Person B. 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