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This study aimed to investigate the effects of postpartum weight changes between 6 weeks and 6 months on changes in the prevalence rates of metabolic syndrome and its components in women who have recently experienced gestational diabetes mellitus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective cohort study included 171 postpartum women with recent gestational diabetes mellitus, who underwent serial weight and metabolic risk factor assessments at 6 weeks and 6 months postpartum. Weight changes between these time points were classified as weight loss (&gt;\u20092 kg), weight stability (\u00b1\u20092 kg), or weight gain (&gt;\u20092 kg). Metabolic syndrome comprised the following metabolic risk factors: large waist circumference, elevated blood pressure, elevated fasting plasma glucose levels, high triglyceride levels, and low high-density lipoprotein cholesterol levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 171 women in our cohort, 30 women (17.5%) lost\u2009&gt;\u20092\u00a0kg of body weight, while 85 (49.7%) maintained a stable weight and 56 (32.8%) gained\u2009&gt;\u20092\u00a0kg. The weight loss group experienced significant changes in the prevalence rates of the following metabolic risk factors compared to the weight stability and weight gain groups: large waist circumference (% change:\u2009\u2212\u200926.7 vs\u2009\u2212\u20095.9 vs 5.4, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004), elevated fasting plasma glucose levels (% change:\u2009\u2212\u20093.4 vs 18.9 vs 26.8, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022), and high triglyceride levels (% change:\u2009\u2212\u200930.0 vs 0 vs\u2009\u2212\u20097.2,\u00a0respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024). A significantly greater decrease in the prevalence of metabolic syndrome was also found in the weight loss group than in the other two groups (% change:\u2009\u2212\u200920.0 vs 11.8 vs 14.2, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Weight changes from 6\u00a0weeks to 6\u00a0months postpartum significantly altered the prevalence rates of metabolic syndrome and its components in women with recent gestational diabetes mellitus. Early postpartum weight loss can reverse metabolic risk factors and reduce the prevalence of metabolic syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>Thai Clinical Trials Registry: Registration no. TCTR20200903001. Date of registration: September 3, 2020. Date of initial participant enrolment: September 7, 2020.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12978-024-01783-4","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T06:01:28Z","timestamp":1712383288000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Impact of postpartum weight change on metabolic syndrome and its components among women with recent gestational diabetes mellitus"],"prefix":"10.1186","volume":"21","author":[{"given":"Chadakarn","family":"Phaloprakarn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasiwan","family":"Suthasmalee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriwan","family":"Tangjitgamol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,6]]},"reference":[{"key":"1783_CR1","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1007\/s11906-018-0812-z","volume":"20","author":"MG Saklayen","year":"2018","unstructured":"Saklayen MG. 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