{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T04:12:01Z","timestamp":1748664721046,"version":"3.41.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:00:00Z","timestamp":1748649600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:00:00Z","timestamp":1748649600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100000193","name":"International Development Research Centre","doi-asserted-by":"publisher","award":["108678001"],"award-info":[{"award-number":["108678001"]}],"id":[{"id":"10.13039\/501100000193","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod Health"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Malaria, acute respiratory infections (ARIs), and diarrhoea are primary causes of morbidity and mortality among children under five years old in Ghana. Despite the implementation of various interventions, the nation struggles to meet relevant health and policy targets. While the potential of mobile health interventions to enhance child health outcomes has been recognized, their impact on prevalent childhood illnesses remains insufficiently explored. This implementation research study aimed to evaluate the effect of a mobile health information system (mHIS) intervention on common childhood illnesses among under-five children residing in rural health districts of Ghana.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>In this quasi-experimental study, we enrolled all children under five years old from randomly selected clusters within the rural intervention and control health districts in the Ashanti region, Ghana between November 2018 and December 2021. The Reach, Effectiveness, Adoption Implementation and Maintenance (RE-AIM) framework was used to design and implement the intervention. The intervention involved a mobile phone-based information system to monitor childhood conditions, offer telemedicine consultations, and deliver child health promotion messages on nutrition and management of common childhood illnesses to caregivers. By employing the average treatment effect (ATET) and difference-in-difference (DiD) analyses, we assessed outcome disparities in diarrhoea, cough, and presumptive malaria.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The incidence of diarrhoea and malaria decreased in the intervention group. The ATET analysis indicated pre-intervention disparities in presumptive malaria with a post-intervention difference between the groups for diarrhoea and presumptive malaria. Results related to cough, used as a proxy for ARIs, did not provide conclusive results across the intervention and control sites based on this intervention. However, the DiD model highlighted an overall statistically significant reduction in diarrhoea and presumptive malaria.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>This study underscores the effectiveness of a mobile phone-based health information system intervention in curbing common childhood morbidities, particularly diarrhoea and presumptive malaria, among under-five children in rural Ghana. This approach demonstrates promise in advancing child health outcomes and contributing to the reduction of prevalent illnesses in resource-constrained settings.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12978-025-01985-4","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T23:02:34Z","timestamp":1748646154000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of a mobile phone-based interactive voice response on common childhood illnesses in Ghana: a quasi-experimental study"],"prefix":"10.1186","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3161-6487","authenticated-orcid":false,"given":"Princess R.","family":"Acheampong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliyu","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sampson","family":"Twumasi-Ankrah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augustina A.","family":"Sylverken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Owusu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy K.","family":"Adjei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Acquah-Gyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellis","family":"Owusu-Dabo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,31]]},"reference":[{"key":"1985_CR1","unstructured":"UN General Assembly. Convention on the Rights of the Child. United Nations, Treaty Series, Vol. 1577, 3 (1989)."},{"key":"1985_CR2","unstructured":"World Health Organization. Under-5 mortality. http:\/\/www.who.int\/gho\/child_health\/mortality\/mortality_under_five_text\/en\/"},{"issue":"10063","key":"1985_CR3","doi-asserted-by":"publisher","first-page":"3027","DOI":"10.1016\/S0140-6736(16)31593-8","volume":"388","author":"L Liu","year":"2016","unstructured":"Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J, et al. Global, regional, and national causes of under-5 mortality in 2000\u201315: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet. 2016;388(10063):3027\u201335.","journal-title":"Lancet"},{"issue":"10018","key":"1985_CR4","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/S0140-6736(15)00837-5","volume":"387","author":"JE Lawn","year":"2016","unstructured":"Lawn JE, Blencowe H, Waiswa P, Amouzou A, Mathers C, Hogan D, et al. 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Each participant verbally consented to being a part of the study. The District Health Directorate provided administrative clearance for the study to be carried out in their district.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"79"}}