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All activities included in the study were carried out according to existing guidance in ethics as indicated in the Universal Declaration on Bioethics and Human Rights adopted by UNESCO (19\/10\/2005); the Council of Europe Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine (1997) and its additional protocol on biomedical research (2005); the Helsinki Declaration (2013) and relevant EU laws (European Parliament and Council Directive 2001\/20\/EC); the Spanish Law on Biomedical Research (14\/2007) and the LOPD (Spanish Law on Personal Data Protection) (3\/2018). Participants received enough information to make an informed decision on participation. All participants gave their informed consent to participate in the study. Informed verbal and written consent were obtained from all participants prior to their participation. 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