{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:46:07Z","timestamp":1791931567054,"version":"4.3.4"},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T00:00:00Z","timestamp":1567728000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T00:00:00Z","timestamp":1567728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-18-2-0040"],"award-info":[{"award-number":["W81XWH-18-2-0040"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003896","name":"Henry M. Jackson Foundation","doi-asserted-by":"publisher","award":["W81XWH-18-2-0040"],"award-info":[{"award-number":["W81XWH-18-2-0040"]}],"id":[{"id":"10.13039\/100003896","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AIDS Res Ther"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12981-019-0240-4","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T06:03:34Z","timestamp":1567749814000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Leveraging early HIV diagnosis and treatment in Thailand to conduct HIV cure research"],"prefix":"10.1186","volume":"16","author":[{"given":"Camilla","family":"Muccini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor A.","family":"Crowell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eug\u00e8ne","family":"Kroon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Sacdalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshmie","family":"Ramautarsing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pich","family":"Seekaew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praphan","family":"Phanuphak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintanat","family":"Ananworanich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donn J.","family":"Colby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nittaya","family":"Phanuphak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,9,6]]},"reference":[{"key":"240_CR1","unstructured":"Country factsheets Thailand 2017. UNAIDS; https:\/\/www.unaids.org\/en\/regionscountries\/countries\/thailand . Accessed 14 Apr 2019."},{"issue":"Suppl 4","key":"240_CR2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S2055-6640(20)31093-1","volume":"2","author":"T Siraprapasiri","year":"2016","unstructured":"Siraprapasiri T, Ongwangdee S, Benjarattanaporn P, Peerapatanapokin W, Sharma M. The impact of Thailand\u2019s public health response to the HIV epidemic 1984\u20132015: understanding the ingredients of success. J Virus Erad. 2016;2(Suppl 4):7\u201314.","journal-title":"J Virus Erad"},{"key":"240_CR3","unstructured":"Data book 2017. UNAIDS; https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/20170720_Data_book_2017_en.pdf . Accessed 14 Apr 2019."},{"key":"240_CR4","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1097\/QAD.0b013e32832baa1c","volume":"23","author":"N Punyacharoensin","year":"2009","unstructured":"Punyacharoensin N, Viwatwongkasem C. Trends in three decades of HIV\/AIDS epidemic in Thailand by nonparametric backcalculation method. AIDS. 2009;23:1143\u201352.","journal-title":"AIDS"},{"key":"240_CR5","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S2055-6640(20)30323-X","volume":"3","author":"S Chaivooth","year":"2017","unstructured":"Chaivooth S, Bhakeecheep S, Ruxrungtham K, Teeraananchai S, Kerr SJ, Teeraratkul A, et al. The challenges of ending AIDS in Asia: outcomes of the Thai National AIDS Universal Coverage Programme, 2000\u20132014. J Virus Erad. 2017;3:192\u20139.","journal-title":"J Virus Erad"},{"key":"240_CR6","unstructured":"UNAIDS. Thailand launches new national strategy to end the AIDS epidemic by 2030. http:\/\/www.unaids.org\/en\/resources\/presscentre\/featurestories\/2017\/September\/20170915_Thailand_NSP . Accessed 20 Apr 2019."},{"key":"240_CR7","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s12981-015-0053-z","volume":"12","author":"W Manosuthi","year":"2015","unstructured":"Manosuthi W, Ongwandee S, Bhakeecheep S, Leechawengwongs M, Ruxrungtham K, Phanuphak P, et al. Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand. AIDS Res Ther. 2015;12:12.","journal-title":"AIDS Res Ther"},{"key":"240_CR8","unstructured":"World Health Organization. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. http:\/\/apps.who.int\/iris\/bitstream\/10665\/186275\/1\/9789241509565_eng.pdf . Accessed 22 June 2019."},{"key":"240_CR9","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0140-6736(14)61181-8","volume":"384","author":"SR Lewin","year":"2014","unstructured":"Lewin SR, Deeks SG, Barr\u00e9-Sinoussi F. Towards a cure for HIV\u2014are we making progress? Lancet. 2014;384:209\u201311.","journal-title":"Lancet"},{"key":"240_CR10","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/nri3262","volume":"12","author":"SG Deeks","year":"2012","unstructured":"Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, et al. Towards an HIV cure: a global scientific strategy. Nat Rev Immunol. 2012;12:607\u201314.","journal-title":"Nat Rev Immunol"},{"key":"240_CR11","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1097\/COH.0000000000000126","volume":"10","author":"P Phanuphak","year":"2015","unstructured":"Phanuphak P, Lo YR. Implementing early diagnosis and treatment: programmatic considerations. Curr Opin HIV AIDS. 2015;10:69\u201375.","journal-title":"Curr Opin HIV AIDS"},{"key":"240_CR12","unstructured":"Data book 2018. UNAIDS; https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/unaids-data-2018_en.pdf . Accessed 25 Apr 2019."},{"key":"240_CR13","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1111\/j.1468-1293.2011.00974.x","volume":"13","author":"EP Chow","year":"2012","unstructured":"Chow EP, Wilson DP, Zhang L. The rate of HIV testing is increasing among men who have sex with men in China. HIV Med. 2012;13:255\u201363.","journal-title":"HIV Med"},{"key":"240_CR14","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1007\/s10461-009-9590-6","volume":"15","author":"G Morineau","year":"2011","unstructured":"Morineau G, Nugrahini N, Riono P, Nurhayati, Girault P, Mustikawati DE, et al. Sexual risk taking, STI and HIV prevalence among men who have sex with men in six Indonesian cities. AIDS Behav. 2011;15:1033\u201344.","journal-title":"AIDS Behav"},{"key":"240_CR15","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1007\/s10461-012-0232-z","volume":"17","author":"T Aung","year":"2013","unstructured":"Aung T, McFarland W, Paw E, Hetherington J. Reaching men who have sex with men in Myanmar: population characteristics, risk and preventive behavior, exposure to health programs. AIDS Behav. 2013;17:1386\u201394.","journal-title":"AIDS Behav"},{"key":"240_CR16","unstructured":"Thailand Country Snapshot 2018. UNAIDS; https:\/\/www.aidsdatahub.org\/sites\/default\/files\/country_review\/Thailand_Country_Card_Sept%202018.pdf . Accessed 30 Apr 2019."},{"key":"240_CR17","unstructured":"UNGASS Country Progress Report: Thailand 2010, National AIDS Prevention and Alleviation Committee; http:\/\/data.unaids.org\/pub\/report\/2010\/thailand_2010_country_progress_report_en.pdf . Accessed 30 Apr 2019."},{"key":"240_CR18","unstructured":"Evaluation of the National HIV prevention program for key affected population, migrant workers and prisoners, Institute for Population and Social Research, Mahidol University, 2013; https:\/\/www.aidsdatahub.org\/sites\/default\/files\/publication\/Evaluation_of_the_National_HIV_prevention_program_for_KAP_Migrants_Prisoners_2013.pdf . Accessed 30 Apr 2019."},{"key":"240_CR19","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1007\/s10461-016-1336-7","volume":"20","author":"LG Johnston","year":"2016","unstructured":"Johnston LG, Steinhaus MC, Sass J, Sirinirund P, Lee C, Benjarattanaporn P. Recent HIV testing among young men who have sex with men in Bangkok and Chiang Mai: HIV testing and prevention strategies must be enhanced in Thailand. AIDS Behav. 2016;20:2023\u201332.","journal-title":"AIDS Behav"},{"issue":"Suppl 3","key":"240_CR20","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1007\/s10461-016-1456-0","volume":"20","author":"V Sapsirisavat","year":"2016","unstructured":"Sapsirisavat V, Phanuphak N, Sophonphan J, Egan JE, Langevattana K, Avihingsanon A, et al. Differences between men who have sex with men (MSM) with low CD4 cell counts at their first HIV test and MSM with higher CD4 counts in Bangkok, Thailand. AIDS Behav. 2016;20(Suppl 3):398\u2013407.","journal-title":"AIDS Behav"},{"key":"240_CR21","unstructured":"Prevention Gap Report 2016, UNAIDS; https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/2016-prevention-gap-report_en.pdf . Accessed 1 May 2019."},{"key":"240_CR22","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1080\/09540121.2014.911810","volume":"26","author":"W Maek-a-nantawat","year":"2014","unstructured":"Maek-a-nantawat W, Phanuphak N, Teeratakulpisarn N, Pakam C, Kanteeranon T, Chaiya O, et al. Attitudes toward, and interest in, the test-and-treat strategy for HIV prevention among Thai men who have sex with men. AIDS Care. 2014;26:1298\u2013302.","journal-title":"AIDS Care"},{"key":"240_CR23","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S2055-6640(20)30235-1","volume":"4","author":"R Wongkanya","year":"2018","unstructured":"Wongkanya R, Pankam T, Wolf S, Pattanachaiwit S, Jantarapakde J, Pengnongyang S, et al. HIV rapid diagnostic testing by lay providers in a key population-led health service programme in Thailand. J Virus Erad. 2018;4:12\u20135.","journal-title":"J Virus Erad"},{"key":"240_CR24","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1080\/09540121.2018.1492697","volume":"30","author":"M Wasantioopapokakorn","year":"2018","unstructured":"Wasantioopapokakorn M, Manopaiboon C, Phoorisri T, Sukkul A, Lertpiriyasuwat C, Ongwandee S, et al. Implementation and assessment of a model to increase HIV testing among men who have sex with men and transgender women in Thailand, 2011\u20132016. AIDS Care. 2018;30:1239\u201345.","journal-title":"AIDS Care"},{"key":"240_CR25","doi-asserted-by":"publisher","first-page":"21326","DOI":"10.7448\/IAS.20.1.21326","volume":"20","author":"T Anand","year":"2017","unstructured":"Anand T, Nitpolprasert C, Trachunthong D, Kerr SJ, Janyam S, Linjongrat D, et al. A novel Online-to-Offline (O2O) model for pre-exposure prophylaxis and HIV testing scale up. J Int AIDS Soc. 2017;20:21326.","journal-title":"J Int AIDS Soc"},{"key":"240_CR26","doi-asserted-by":"publisher","first-page":"e25118","DOI":"10.1002\/jia2.25118","volume":"21","author":"N Phanuphak","year":"2018","unstructured":"Phanuphak N, Anand T, Jantarapakde J, Nitpolprasert C, Himmad K, Sungsing T, et al. What would you choose: Online or Offline or Mixed services? Feasibility of online HIV counselling and testing among Thai men who have sex with men and transgender women and factors associated with service uptake. J Int AIDS Soc. 2018;21:e25118.","journal-title":"J Int AIDS Soc"},{"key":"240_CR27","unstructured":"Janamnuaysook R, Samitpol K, Ketwongsa P, Chancham A, Kongkapan J, Mingkwanrungruang P, et al. Integrated gender affirmative hormone treatment services improve access to and retention in HIV testing, syphilis testing and pre-exposure prophylaxis (PrEP) service uptake among transgender women in Thailand. IN: AIDS 2018: 22nd international AIDS conference, Amsterdam, Netherlands, July 23\u201327, 2018. Abstract THAC0204."},{"key":"240_CR28","unstructured":"Colby D. PrEP or Peril: rolling out PrEP in the private sector without subsidy or government support. In: AIDS 2018: 22nd international AIDS conference, Amsterdam, Netherlands, July 23\u201327, 2018."},{"key":"240_CR29","doi-asserted-by":"publisher","first-page":"e25129","DOI":"10.1002\/jia2.25129","volume":"21","author":"C Suraratdecha","year":"2018","unstructured":"Suraratdecha C, Stuart RM, Manopaiboon C, Green D, Lertpiriyasuwat C, Wilson DP, et al. Cost and cost-effectiveness analysis of pre-exposure prophylaxis among men who have sex with men in two hospitals in Thailand. J Int AIDS Soc. 2018;21:e25129.","journal-title":"J Int AIDS Soc"},{"key":"240_CR30","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1071\/SH18065","volume":"15","author":"N Phanuphak","year":"2018","unstructured":"Phanuphak N, Sungsing T, Jantarapakde J, Pengnonyang S, Trachunthong D, Mingkwanrungruang P, et al. Princess PrEP program: the first key population-led model to deliver pre-exposure prophylaxis to key populations by key populations in Thailand. Sex Health. 2018;15:542\u201355.","journal-title":"Sex Health"},{"key":"240_CR31","unstructured":"Vannakit R, Thammatach-aree J, Rungtanatada K, Linjongrat D, Janyam S, Chanlearn P, et al. From \u201cnice-to-have\u201d to \u201cnecessary\u201d: increases in domestic financing and perceived value of key population-lead HIV services by the Thai government as international donor funding transitions. In: 10th international conference on HIV science, July 21\u201324, 2019, Mexico City. Abstract TUAD0302."},{"key":"240_CR32","unstructured":"Funding boost for healthcare. http:\/\/www.nationmultimedia.com\/detail\/Economy\/30364003 . Accessed 16 Aug 2019."},{"key":"240_CR33","unstructured":"NHSO board adds PrEP for high risk populations to fiscal year 2020 budget; https:\/\/www.nhso.go.th\/frontend\/NewsInformationDetail.aspx?newsid=MjUzMg . Accessed 16 Aug 2019."},{"key":"240_CR34","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.jaci.2014.05.026","volume":"134","author":"JD Siliciano","year":"2014","unstructured":"Siliciano JD, Siliciano RF. Recent developments in the search for a cure for HIV-1 infection: targeting the latent reservoir for HIV-1. J Allergy Clin Immunol. 2014;134:12\u20139.","journal-title":"J Allergy Clin Immunol"},{"key":"240_CR35","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.ebiom.2016.07.024","volume":"11","author":"J Ananworanich","year":"2016","unstructured":"Ananworanich J, Chomont N, Eller LA, Kroon E, Tovanabutra S, Bose M, et al. HIV DNA set point is rapidly established in acute HIV infection and dramatically reduced by early ART. EBioMedicine. 2016;11:68\u201372.","journal-title":"EBioMedicine"},{"key":"240_CR36","unstructured":"Vannakit R, Jantarapakde J, Pengnongyang S, Pankam T, Trachunthong D, Pussadeeet K, et al. High linkage to ART and HIV RNA suppression among HIV-positive MSM and TG, along with high PrEP uptake among HIV-negative MSM and TG, through community-led health service model in Thailand. In: IAS 2017: 9th IAS conference on HIV science, Paris, France, July 23\u201326, 2017. Abstract TUPED1313."},{"key":"240_CR37","doi-asserted-by":"publisher","first-page":"e25186","DOI":"10.1002\/jia2.25186","volume":"21","author":"N Phanuphak","year":"2018","unstructured":"Phanuphak N, Pattanachaiwit S, Pankam T, Teeratakulpisarn N, Chamnan P, Pathipvanich P, et al. Sexually transmitted infections and HIV RNA levels in blood and anogenital compartments among Thai men who have sex with men before and after antiretroviral therapy: implication for treatment as prevention programme. J Int AIDS Soc. 2018;21:e25186.","journal-title":"J Int AIDS Soc"},{"key":"240_CR38","unstructured":"Phanuphak N, Chamnan P, Pathipvanich P, Thongpaen S, Nonenoy S, Jantarapakde J, et al. Factors associated with uptake of immediate ART regardless of CD4 count among Thai MSM and TG in the Test and Treat program. In: AIDS 2014: 20th international AIDS conference, Melbourne, Australia, July 20\u201325, 2014. Abstract WEPE431."},{"key":"240_CR39","doi-asserted-by":"publisher","first-page":"e0201171","DOI":"10.1371\/journal.pone.0201171","volume":"13","author":"S Ongwandee","year":"2018","unstructured":"Ongwandee S, Lertpiriyasuwat C, Khawcharoenporn T, Chetchotisak P, Thiansukhon E, Leerattanapetch N, et al. Implementation of a test, treat, and prevent HIV program among men who have sex with men and transgender women in Thailand, 2015\u20132016. PLoS ONE. 2018;13:e0201171.","journal-title":"PLoS ONE"},{"key":"240_CR40","doi-asserted-by":"publisher","first-page":"e0203294","DOI":"10.1371\/journal.pone.0203294","volume":"13","author":"P Seekaew","year":"2018","unstructured":"Seekaew P, Pengnonyang S, Jantarapakde J, Sungsing T, Rodbumrung P, Trachunthong D, et al. Characteristics and HIV epidemiologic profiles of men who have sex with men and transgender women in key population-led test and treat cohorts in Thailand. PLoS ONE. 2018;13:e0203294.","journal-title":"PLoS ONE"},{"key":"240_CR41","unstructured":"Thai MoH\/NAC\/UNAIDS \u201cAIDS Zero Portal: Data use tool\u201d. http:\/\/aidszeroportal.org . Accessed 16 Aug 2019."},{"key":"240_CR42","unstructured":"Personal communication from Pich Seekaew, PREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand."},{"key":"240_CR43","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1093\/infdis\/jir793","volume":"205","author":"BM Branson","year":"2012","unstructured":"Branson BM, Stekler JD. Detection of acute HIV infection: we can\u2019t close the window. J Infect Dis. 2012;205:521\u20134.","journal-title":"J Infect Dis"},{"key":"240_CR44","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1742-4690-10-56","volume":"10","author":"J Ananworanich","year":"2013","unstructured":"Ananworanich J, Fletcher JLK, Pinyakorn S, van Griensven F, Vandergeeten C, Schuetz A, et al. A novel acute HIV infection staging system based on 4th generation immunoassay. Retrovirology. 2013;10:56.","journal-title":"Retrovirology."},{"key":"240_CR45","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1097\/QAD.0000000000000616","volume":"29","author":"MS De Souza","year":"2015","unstructured":"De Souza MS, Phanuphak N, Pinyakorn S, Trichavaroj R, Pattanachaiwit S, Chomchey N, et al. Impact of nucleic acid testing relative to antigen\/antibody combination immunoassay on the detection of acute HIV infection. AIDS. 2015;29:793\u2013800.","journal-title":"AIDS"},{"key":"240_CR46","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1097\/QAD.0000000000001956","volume":"32","author":"E Kroon","year":"2018","unstructured":"Kroon E, Pham PT, Sirivichayakul S, Trichavaroj R, Colby DJ, Pinyakorn S, et al. Transmission dynamics among participants initiating antiretroviral therapy upon diagnosis of early acute HIV-1 infection in Thailand. AIDS. 2018;32:2373\u201381.","journal-title":"AIDS"},{"key":"240_CR47","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aag1809","author":"H Takata","year":"2017","unstructured":"Takata H, Buranapraditkun S, Kessing C, Fletcher JL, Muir R, Tardif V, et al. Delayed differentiation of potent effector CD8+ T cells reducing viremia and reservoir seeding in acute HIV infection. Sci Transl Med. 2017. https:\/\/doi.org\/10.1126\/scitranslmed.aag1809 .","journal-title":"Sci Transl Med."},{"key":"240_CR48","doi-asserted-by":"publisher","first-page":"e1004543","DOI":"10.1371\/journal.ppat.1004543","volume":"10","author":"A Schuetz","year":"2014","unstructured":"Schuetz A, Deleage C, Sereti I, Rerknimitr R, Phanuphak N, Phuang-Ngern Y, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS Pathog. 2014;10:e1004543.","journal-title":"PLoS Pathog"},{"key":"240_CR49","doi-asserted-by":"publisher","first-page":"e0142600","DOI":"10.1371\/journal.pone.0142600","volume":"10","author":"VG Valcour","year":"2015","unstructured":"Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JLK, et al. Neurological response to cART vs. cART plus integrase inhibitor and CCR1 antagonist initiated during acute HIV. PLoS ONE. 2015;10:e0142600.","journal-title":"PLoS ONE"},{"key":"240_CR50","doi-asserted-by":"publisher","first-page":"32947","DOI":"10.1038\/srep32947","volume":"6","author":"M Hoenigl","year":"2016","unstructured":"Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, et al. Rapid HIV viral load suppression in those initiating antiretroviral therapy at first visit after HIV diagnosis. Sci Rep. 2016;6:32947.","journal-title":"Sci Rep"},{"key":"240_CR51","unstructured":"Seekaew P, Teeratakulpisarn N, Surapuchong P, Teeratakulpisarn S, Amatavete S, Jomja P, et al. Same-day ART initiation in HIV\/STI testing center in Bangkok, Thailand: initial results from implementation research. In: AIDS 2018: 22nd international AIDS conference, Amsterdam, Netherlands, July 23\u201327, 2018. Abstract THAC0403."},{"key":"240_CR52","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.1097\/QAD.0000000000001148","volume":"30","author":"TA Crowell","year":"2016","unstructured":"Crowell TA, Phanuphak N, Pinyakorn S, Kroon E, Fletcher JL, Colby D, et al. Virologic failure is uncommon after treatment initiation during acute HIV infection. AIDS. 2016;30:1943\u201350.","journal-title":"AIDS"},{"key":"240_CR53","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/jmv.24023","volume":"87","author":"S Gallien","year":"2015","unstructured":"Gallien S, Flandre P, Nguyen N, De Castro N, Molina JM, Delaugerre C. Safety and efficacy of coformulated efavirenz\/emtricitabine\/tenofovir single-tablet regimen in treatment-naive patients infected with HIV-1. J Med Virol. 2015;87:187\u201391.","journal-title":"J Med Virol"},{"key":"240_CR54","doi-asserted-by":"publisher","first-page":"e1001290","DOI":"10.1371\/journal.pmed.1001290","volume":"9","author":"TB Campbell","year":"2012","unstructured":"Campbell TB, Smeaton LM, Kumarasamy N, Flanigan T, Klingman KL, Firnhaber C, et al. Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings. PLoS Med. 2012;9:e1001290.","journal-title":"PLoS Med"},{"key":"240_CR55","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1097\/QAI.0000000000001436","volume":"76","author":"C Sacdalan","year":"2017","unstructured":"Sacdalan C, Crowell T, Colby DJ, Kroon E, Chan P, Pinyakorn S, et al. Brief report: safety of frequent blood sampling in research participants in an acute HIV infection cohort in Thailand. J Acquir Immune Defic Syndr. 2017;76:98\u2013101.","journal-title":"J Acquir Immune Defic Syndr"},{"key":"240_CR56","doi-asserted-by":"publisher","first-page":"e25260","DOI":"10.1002\/jia2.25260","volume":"22","author":"GE Henderson","year":"2019","unstructured":"Henderson GE, Waltz M, Meagher K, Cadigan RJ, Jupimai T, Isaacson S, et al. Going off antiretroviral treatment in a closely monitored HIV \u201ccure\u201d trial: longitudinal assessments of acutely diagnosed trial participants and decliners. J Int AIDS Soc. 2019;22:e25260.","journal-title":"J Int AIDS Soc"},{"key":"240_CR57","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1097\/QAI.0000000000001780","volume":"79","author":"M Chintanaphol","year":"2018","unstructured":"Chintanaphol M, Sacdalan C, Chottanapund S, Pinyakorn S, Crowell TA, Kroon E, et al. Brief report: safety and tolerability of inguinal lymph node biopsy in individuals with acute HIV infection in Thailand. J Acquir Immune Defic Syndr. 2018;79:244\u20138.","journal-title":"J Acquir Immune Defic Syndr"},{"key":"240_CR58","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S2055-6640(20)30236-3","volume":"4","author":"P Chan","year":"2018","unstructured":"Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, et al. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. J Virus Erad. 2018;4:16\u201320.","journal-title":"J Virus Erad"},{"key":"240_CR59","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1038\/s41591-018-0026-6","volume":"24","author":"DJ Colby","year":"2018","unstructured":"Colby DJ, Trautmann L, Pinyakorn S, Leyre L, Pagliuzza A, Kroon E, et al. Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection. Nat Med. 2018;24:923\u20136.","journal-title":"Nat Med"},{"key":"240_CR60","unstructured":"Crowell TA, Colby DJ, Pinyakorn S, Intasan J, Benjapornpong K, Tanjnareel K, et al. HIV-specific broadly-neutralizing monoclonal antibody, VRC01, minimally impacts time to viral rebound following treatment interruption in virologically-suppressed, HIV-infected participants who initiated antiretroviral therapy during acute HIV infection. In: IAS 2017: 9th IAS conference on HIV science, Paris, France, July 23\u201326, 2017. Abstract TUAB0106LB."},{"key":"240_CR61","unstructured":"Kroon E, Ananworanich J, Eubanks K, Intasan J, Pinyakorn S, Chomont N, et al. Effect of Vorinostat, Hydroxychloroquine and Maraviroc combination therapy on viremia following treatment interruption in individuals initiating ART during acute HIV infection. In: AIDS 2016: 21st international AIDS conference Durban, South Africa, July 18\u201322, 2016. Abstract 10535."},{"key":"240_CR62","unstructured":"Ananworanich J. AD26 & MVA vaccines in acutely treated HIV: safety, immunogenicity and viral rebound. In: Keystone symposia on functional cures and the eradication of HIV, Whistler, British Columbia, March 24\u201328, 2019."}],"container-title":["AIDS Research and Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12981-019-0240-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12981-019-0240-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12981-019-0240-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T18:10:53Z","timestamp":1664302253000},"score":1,"resource":{"primary":{"URL":"https:\/\/aidsrestherapy.biomedcentral.com\/articles\/10.1186\/s12981-019-0240-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,6]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["240"],"URL":"https:\/\/doi.org\/10.1186\/s12981-019-0240-4","relation":{},"ISSN":["1742-6405"],"issn-type":[{"value":"1742-6405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,6]]},"assertion":[{"value":"28 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"JA has received honoraria for participating in advisory meetings for ViiV Healthcare, Gilead, Merck, Roche and AbbVie. RR has received speaker fees and travel support from Gilead. CM, TC, EK, CS, PS, PP, DC, NP declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"25"}}