{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:11:37Z","timestamp":1784265097838,"version":"3.55.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,1,16]],"date-time":"2015-01-16T00:00:00Z","timestamp":1421366400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12985-014-0235-7","type":"journal-article","created":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T11:49:07Z","timestamp":1421322547000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["Complete genome sequencing and phylogenetic analysis of dengue type 1 virus isolated from Jeddah, Saudi Arabia"],"prefix":"10.1186","volume":"12","author":[{"given":"Esam I","family":"Azhar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar M","family":"Hashem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif A","family":"El-Kafrawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Abol-Ela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adly MM","family":"Abd-Alla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayed Sartaj","family":"Sohrab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suha A","family":"Farraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah A","family":"Othman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huda G","family":"Ben-Helaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ashshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq A","family":"Madani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghazi","family":"Jamjoom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,1,16]]},"reference":[{"key":"235_CR1","doi-asserted-by":"publisher","first-page":"128","DOI":"10.4269\/ajtmh.2010.09-0346","volume":"82","author":"JL San Mart\u00edn","year":"2010","unstructured":"San Mart\u00edn JL, Brathwaite O, Zambrano B, Sol\u00f3rzano JO, Bouckenooghe A, Dayan GH, et al. The epidemiology of dengue in the Americas over the last three decades: A worrisome reality. Am J Trop Med Hyg. 2010;82:128\u201335.","journal-title":"Am J Trop Med Hyg"},{"key":"235_CR2","first-page":"849","volume":"48","author":"M Anoop","year":"2010","unstructured":"Anoop M, Issac A, Mathew T, Philip S, Kareem NA, Unnikrishnan R, et al. Genetic characterization of dengue virus serotypes causing concurrent infection in an outbreak in Ernakulam, Kerala, South India. Indian J ExpBiol. 2010;48:849\u201357.","journal-title":"Indian J ExpBiol"},{"key":"235_CR3","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1590\/S0036-46652011000600004","volume":"53","author":"RM Figueiredo","year":"2011","unstructured":"Figueiredo RM, Naveca FG, Oliveira CM, BastosMde S, Mour\u00e3o MP, VianaSde S, et al. Co-infection of Dengue virus by serotypes 3 and 4 in patients from Amazonas, Brazil. Rev Inst Med Trop Sao Paulo. 2011;53:321\u20133.","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"235_CR4","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1097\/01.qco.0000244047.31135.fa","volume":"19","author":"S Green","year":"2006","unstructured":"Green S, Rothman A. Immunopathological mechanisms in dengue and dengue hemorrhagic fever. CurrOpin Infect Dis. 2006;19:429\u201336.","journal-title":"CurrOpin Infect Dis."},{"key":"235_CR5","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1146\/annurev.mi.44.100190.003245","volume":"44","author":"TJ Chambers","year":"1990","unstructured":"Chambers TJ, Hahn CS, Galler R, Rice CM. Flavivirus genome organization, expression, and replication. Annu Rev Microbiol. 1990;44:649\u2013488.","journal-title":"Annu Rev Microbiol"},{"key":"235_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11262-012-0756-3","volume":"45","author":"M Anoop","year":"2012","unstructured":"Anoop M, Mathew AJ, Jayakumar B, Issac A, Nair S, Abraham R, et al. Complete genome sequencing and evolutionary analysis of dengue virus serotype 1 isolates from an outbreak in Kerala, South India. Virus Genes. 2012;45:1\u201313.","journal-title":"Virus Genes"},{"key":"235_CR7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/S1567-1348(03)00004-2","volume":"3","author":"EC Holmes","year":"2003","unstructured":"Holmes EC, Twiddy SS. The origin, emergence and evolutionary genetics of dengue virus. Infect Genet Evol. 2003;3:19\u201328.","journal-title":"Infect Genet Evol"},{"key":"235_CR8","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1146\/annurev.micro.62.081307.163005","volume":"62","author":"JL Kyle","year":"2008","unstructured":"Kyle JL, Harris E. Global spread and persistence of dengue. Annu Rev Microbiol. 2008;62:71\u201392.","journal-title":"Annu Rev Microbiol"},{"key":"235_CR9","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/S0065-3527(03)59009-1","volume":"59","author":"R Rico-Hesse","year":"2003","unstructured":"Rico-Hesse R. Microevolution and virulence of dengue virus. Adv Virus Res. 2003;59:315\u201341.","journal-title":"Adv Virus Res"},{"key":"235_CR10","first-page":"45","volume":"338","author":"R Rico-Hesse","year":"2010","unstructured":"Rico-Hesse R. Dengue virus virulence and transmission determinants. Curr Top Microbiol Immunol. 2010;338:45\u201355.","journal-title":"Curr Top Microbiol Immunol"},{"key":"235_CR11","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1006\/viro.1997.8504","volume":"230","author":"R Rico-Hesse","year":"1997","unstructured":"Rico-Hesse R, Harrison LM, Salas RA, Tovar D, Nisalak A, Ramos C, et al. Origins of dengue type 2 viruses associated with increased pathogenicity in the Americas. Virology. 1997;230:244\u201351.","journal-title":"Virology"},{"key":"235_CR12","doi-asserted-by":"publisher","first-page":"800","DOI":"10.3201\/eid0907.030038","volume":"9","author":"WB Messer","year":"2003","unstructured":"Messer WB, Gubler DJ, Harris E, Sivananthan K, de Silva AM. Emergence and global spread of a dengue serotype 3, subtype III virus. Emerg Infect Dis. 2003;9:800\u20139.","journal-title":"Emerg Infect Dis"},{"key":"235_CR13","first-page":"13","volume":"27","author":"M Fakeeh","year":"2003","unstructured":"Fakeeh M, Zaki AM. Dengue in Jeddah, Saudi Arabia, 1994\u20132002. Dengue Bull. 2003;27:13\u20138.","journal-title":"Dengue Bull"},{"key":"235_CR14","doi-asserted-by":"publisher","first-page":"503","DOI":"10.3855\/jidc.1038","volume":"4","author":"MM Ahmed","year":"2010","unstructured":"Ahmed MM. Clinical profile of dengue fever infection in King Abdul Aziz University Hospital Saudi Arabia. J Infect Dev Ctries. 2010;4:503\u201310.","journal-title":"J Infect Dev Ctries"},{"key":"235_CR15","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.actatropica.2007.09.005","volume":"105","author":"NA Khan","year":"2008","unstructured":"Khan NA, Azhar EI, El-Fiky S, Madani HH, Abuljadial MA, Ashshi AM, et al. Clinical profile and outcome of hospitalized patients during first outbreak of dengue in Makkah, Saudi Arabia. Acta Trop. 2008;105:39\u201344.","journal-title":"Acta Trop"},{"key":"235_CR16","first-page":"9","volume":"18","author":"M Ayyub","year":"2006","unstructured":"Ayyub M, Khazindar AM, Lubbad EH, Barlas S, Alfi AY, Al-Ukayli S. Characteristics of dengue fever in a large public hospital, Jeddah, Saudi Arabia. J Ayub Med Coll Abbottabad. 2006;18:9\u201313.","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"235_CR17","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/1471-2334-13-136","volume":"13","author":"TA Madani","year":"2013","unstructured":"Madani TA, Abuelzein e-TM, Al-Bar HM, Azhar EI, Kao M, Alshoeb HO, et al. Outbreak of viral hemorrhagic fever caused by dengue virus type 3 in Al-Mukalla, Yemen. BMC Infect Dis. 2013;13:136.","journal-title":"BMC Infect Dis"},{"key":"235_CR18","doi-asserted-by":"crossref","unstructured":"El-Badry AA, El-Beshbishy HA, Al-Ali KH, Al-Hejin AM, El-Sayed WSM: Molecular and seroprevalence of imported dengue virus infection in Al-Madinah, Saudi Arabia. Comp Clin Pathol. 2013. doi.org\/10.1007\/s00580-013-1704-x.","DOI":"10.1007\/s00580-013-1704-x"},{"key":"235_CR19","doi-asserted-by":"crossref","first-page":"764","DOI":"10.4269\/ajtmh.2001.65.764","volume":"65","author":"M Fakeeh","year":"2001","unstructured":"Fakeeh M, Zaki AM. Virologic and serologic surveillance for dengue fever in Jeddah, Saudi Arabia, 1994\u20131999. Am J Trop Med Hyg. 2001;65:764\u20137.","journal-title":"Am J Trop Med Hyg"},{"key":"235_CR20","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1111\/j.1365-3156.2008.02037.x","volume":"13","author":"A Zaki","year":"2008","unstructured":"Zaki A, Perera D, Jahan SS, Cardosa MJ. Phylogeny of dengue viruses circulating in Jeddah, Saudi Arabia: 1994 to 2006. Trop Med Int Health. 2008;13:584\u201392.","journal-title":"Trop Med Int Health"},{"key":"235_CR21","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1099\/0022-1317-82-6-1283","volume":"82","author":"HJ Tolou","year":"2001","unstructured":"Tolou HJ, Couissinier-Paris P, Durand JP, Mercier V, de Pina JJ, de Micco P, et al. Evidence for recombination in natural populations of dengue virus type 1 based on the analysis of complete genome sequences. J Gen Virol. 2001;82:1283\u201390.","journal-title":"J Gen Virol"},{"key":"235_CR22","doi-asserted-by":"publisher","first-page":"2323","DOI":"10.1128\/JCM.40.7.2323-2330.2002","volume":"40","author":"C Drosten","year":"2002","unstructured":"Drosten C, G\u00f6ttig S, Schilling S, Asper M, Panning M, Schmitz H, et al. Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR. J Clin Microbiol. 2002;40:2323\u201330.","journal-title":"J Clin Microbiol"},{"key":"235_CR23","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.jviromet.2010.06.013","volume":"169","author":"JG Christenbury","year":"2010","unstructured":"Christenbury JG, Aw PP, Ong SH, Schreiber MJ, Chow A, Gubler DJ, et al. A method for full genome sequencing of all four serotypes of the dengue virus. J Virol Methods. 2010;169:202\u20136.","journal-title":"J Virol Methods"},{"key":"235_CR24","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1093\/bioinformatics\/btq467","volume":"26","author":"DP Martin","year":"2010","unstructured":"Martin DP, Lemey P, Lott M, Moulton V, Posada D, Lefeuvre P. RDP3: a flexible and fast computer program for analyzing recombination. Bioinformatics. 2010;26:2462\u20133.","journal-title":"Bioinformatics"}],"container-title":["Virology Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-014-0235-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12985-014-0235-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-014-0235-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-014-0235-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T18:41:25Z","timestamp":1553625685000},"score":1,"resource":{"primary":{"URL":"https:\/\/virologyj.biomedcentral.com\/articles\/10.1186\/s12985-014-0235-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,16]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["235"],"URL":"https:\/\/doi.org\/10.1186\/s12985-014-0235-7","relation":{},"ISSN":["1743-422X"],"issn-type":[{"value":"1743-422X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,16]]},"assertion":[{"value":"30 September 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 January 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"1"}}