{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:39:45Z","timestamp":1787020785552,"version":"build-2736575974"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"Guangxi Natural Science Foundation project","award":["11-31-03"],"award-info":[{"award-number":["11-31-03"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12985-017-0859-5","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T07:57:43Z","timestamp":1507276663000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A study of Epstein-Barr virus infection in the Chinese tree shrew(Tupaia belangeri chinensis)"],"prefix":"10.1186","volume":"14","author":[{"given":"Zhi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglin","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjing","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anzhou","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,6]]},"reference":[{"key":"859_CR1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12985-015-0368-3","volume":"12","author":"L Sun","year":"2015","unstructured":"Sun L, Che K, Zhao Z, Liu S, Xing X, Luo B. Sequence analysis of Epstein-Barr virus (EBV) early genes BARF1 and BHRF1 in NK\/T cell lymphoma from Northern China. Virol J. 2015;12:135.","journal-title":"Virol J"},{"issue":"1","key":"859_CR2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/infdis\/jis646","volume":"207","author":"HH Balfour Jr","year":"2013","unstructured":"Balfour HH Jr, Odumade OA, Schmeling DO, Mullan BD, Ed JA, Knight JA, et al. Behavioral, virologic, and immunologic factors associated with acquisition and severity of primary Epstein-Barr virus infection in university students. J Infect Dis. 2013;207(1):80\u20138.","journal-title":"J Infect Dis"},{"issue":"11","key":"859_CR3","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.7150\/ijbs.16564","volume":"12","author":"H Li","year":"2016","unstructured":"Li H, Liu S, Hu J, Luo X, Li N, MB A, et al. Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis. Int J Biol Sci. 2016;12(11):1309\u201318.","journal-title":"Int J Biol Sci"},{"issue":"14","key":"859_CR4","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/S0024-3205(99)00214-3","volume":"65","author":"DA Thorley-Lawson","year":"1999","unstructured":"Thorley-Lawson DA, Babcock GJ. A model for persistent infection with Epstein-Barr virus: the stealth virus of human B cells. Life Sci. 1999;65(14):1433\u201353.","journal-title":"Life Sci"},{"issue":"4","key":"859_CR5","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S1074-7613(00)00049-2","volume":"13","author":"GJ Babcock","year":"2000","unstructured":"Babcock GJ, Hochberg D, Thorley-Lawson AD. The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell. Immunity. 2000;13(4):497\u2013506.","journal-title":"Immunity"},{"issue":"10","key":"859_CR6","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1158\/0008-5472.CAN-04-0079","volume":"64","author":"M Sugimoto","year":"2004","unstructured":"Sugimoto M, Tahara H, Ide T, Furuichi Y. Steps involved in immortalization and tumorigenesis in human B-lymphoblastoid cell lines transformed by Epstein-Barr virus. Cancer Res. 2004;64(10):3361\u20134.","journal-title":"Cancer Res"},{"issue":"10","key":"859_CR7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nri1201","volume":"3","author":"R Kuppers","year":"2003","unstructured":"Kuppers R. B cells under influence: transformation of B cells by Epstein-Barr virus. Nat Rev Immunol. 2003;3(10):801\u201312.","journal-title":"Nat Rev Immunol"},{"issue":"40","key":"859_CR8","doi-asserted-by":"crossref","first-page":"14935","DOI":"10.1073\/pnas.0509988103","volume":"103","author":"GL Kelly","year":"2006","unstructured":"Kelly GL, Milner AE, Baldwin GS, Bell AI, Rickinson AB. Three restricted forms of Epstein-Barr virus latency counteracting apoptosis in c-myc-expressing Burkitt lymphoma cells. Proc Natl Acad Sci U S A. 2006;103(40):14935\u201340.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"859_CR9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002164","volume":"7","author":"L Cancian","year":"2011","unstructured":"Cancian L, Bosshard R, Lucchesi W, Karstegl CE, Farrell PJ. C-terminal region of EBNA-2 determines the superior transforming ability of type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7. PLoS Pathog. 2011;7(7):e1002164.","journal-title":"PLoS Pathog"},{"issue":"4","key":"859_CR10","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.cell.2011.12.031","volume":"148","author":"B Zhang","year":"2012","unstructured":"Zhang B, Kracker S, Yasuda T, Casola S, Vanneman M, Homig-Holzel C, et al. Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model. Cell. 2012;148(4):739\u201351.","journal-title":"Cell"},{"issue":"9","key":"859_CR11","doi-asserted-by":"crossref","first-page":"6611","DOI":"10.1128\/JVI.71.9.6611-6618.1997","volume":"71","author":"S Harada","year":"1997","unstructured":"Harada S, Kieff E. Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation. J Virol. 1997;71(9):6611\u20138.","journal-title":"J Virol"},{"issue":"18","key":"859_CR12","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1093\/jnci\/djs320","volume":"104","author":"FH Xu","year":"2012","unstructured":"Xu FH, Xiong D, Xu YF, Cao SM, Xue WQ, Qin HD, et al. An epidemiological and molecular study of the relationship between smoking, risk of nasopharyngeal carcinoma, and Epstein-Barr virus activation. J Natl Cancer Inst. 2012;104(18):1396\u2013410.","journal-title":"J Natl Cancer Inst"},{"issue":"9","key":"859_CR13","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1073\/pnas.70.9.2487","volume":"70","author":"T Shope","year":"1973","unstructured":"Shope T, Dechairo D, Miller G. Malignant lymphoma in cottontop marmosets after inoculation with Epstein-Barr virus. Proc Natl Acad Sci U S A. 1973;70(9):2487\u201391.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"859_CR14","first-page":"969","volume":"145","author":"G Niedobitek","year":"1994","unstructured":"Niedobitek G, Agathanggelou A, Finerty S, Tierney R, Watkins P, Jones EL, et al. Latent Epstein-Barr virus infection in cottontop tamarins. A possible model for Epstein-Barr virus infection in humans. Am J Pathol. 1994;145(4):969\u201378.","journal-title":"Am J Pathol"},{"issue":"4700","key":"859_CR15","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1126\/science.2986287","volume":"228","author":"ML Cleary","year":"1985","unstructured":"Cleary ML, Epstein MA, Finerty S, Dorfman RF, Bornkamm GW, Kirkwood JK, et al. Individual tumors of multifocal EB virus-induced malignant lymphomas in tamarins arise from different B-cell clones. Science. 1985;228(4700):722\u20134.","journal-title":"Science"},{"issue":"6187","key":"859_CR16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/335256a0","volume":"335","author":"DE Mosier","year":"1988","unstructured":"Mosier DE, Gulizia RJ, Baird SM, Wilson DB. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature. 1988;335(6187):256\u20139.","journal-title":"Nature"},{"issue":"3","key":"859_CR17","first-page":"288","volume":"120","author":"V Molinie","year":"1996","unstructured":"Molinie V, Pouchot J, Navratil E, Aubert F, Vinceneux P, Barge J. Primary Epstein-Barr virus-related non-Hodgkin's lymphoma of the pleural cavity following long-standing tuberculous empyema. Arch Pathol Lab Med. 1996;120(3):288\u201391.","journal-title":"Arch Pathol Lab Med"},{"issue":"6","key":"859_CR18","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.celrep.2013.11.041","volume":"5","author":"O Chijioke","year":"2013","unstructured":"Chijioke O, Muller A, Feederle R, Barros MH, Krieg C, Emmel V, et al. Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection. Cell Rep. 2013;5(6):1489\u201398.","journal-title":"Cell Rep"},{"issue":"7","key":"859_CR19","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1158\/2326-6066.CIR-14-0242","volume":"3","author":"AS Hartlage","year":"2015","unstructured":"Hartlage AS, Liu T, Patton JT, Garman SL, Zhang X, Kurt H, et al. The Epstein-Barr Virus Lytic Protein BZLF1 as a Candidate Target Antigen for Vaccine Development. Cancer Immunol Res. 2015;3(7):787\u201394.","journal-title":"Cancer Immunol Res"},{"issue":"12","key":"859_CR20","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1002\/j.1460-2075.1996.tb00674.x","volume":"15","author":"JB Wilson","year":"1996","unstructured":"Wilson JB, Bell JL, Levine AJ. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice. EMBO J. 1996;15(12):3117\u201326.","journal-title":"EMBO J"},{"issue":"1","key":"859_CR21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1476-4598-10-11","volume":"10","author":"A Hannigan","year":"2011","unstructured":"Hannigan A, Qureshi AM, Nixon C, Tsimbouri PM, Jones S, Philbey AW, et al. Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo. Mol Cancer. 2011;10(1):11.","journal-title":"Mol Cancer"},{"issue":"20","key":"859_CR22","doi-asserted-by":"crossref","first-page":"11963","DOI":"10.1073\/pnas.95.20.11963","volume":"95","author":"W Kulwichit","year":"1998","unstructured":"Kulwichit W, Edwards RH, Davenport EM, Baskar JF, Godfrey V, Raab-Traub N. Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice. Proc Natl Acad Sci U S A. 1998;95(20):11963\u20138.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"859_CR23","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jmv.21102","volume":"80","author":"K Takashima","year":"2008","unstructured":"Takashima K, Ohashi M, Kitamura Y, Ando K, Nagashima K, Sugihara H, et al. A new animal model for primary and persistent Epstein-Barr virus infection: human EBV-infected rabbit characteristics determined using sequential imaging and pathological analysis. J Med Virol. 2008;80(3):455\u201366.","journal-title":"J Med Virol"},{"issue":"6","key":"859_CR24","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/jmv.21597","volume":"82","author":"K Okuno","year":"2010","unstructured":"Okuno K, Takashima K, Kanai K, Ohashi M, Hyuga R, Sugihara H, et al. Epstein-Barr virus can infect rabbits by the intranasal or peroral route: an animal model for natural primary EBV infection in humans. J Med Virol. 2010;82(6):977\u201386.","journal-title":"J Med Virol"},{"key":"859_CR25","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12985-015-0260-1","volume":"12","author":"G Khan","year":"2015","unstructured":"Khan G, Ahmed W, Philip PS, Ali MH, Adem A. Healthy rabbits are susceptible to Epstein-Barr virus infection and infected cells proliferate in immunosuppressed animals. Virol J. 2015;12:28.","journal-title":"Virol J"},{"issue":"1","key":"859_CR26","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000318882","volume":"54","author":"K Kanai","year":"2011","unstructured":"Kanai K, Kato K, Sano H, Nagata K, Okuno K, Kuwamoto S, et al. In vitro Epstein-Barr virus infection model of rabbit lymphocytes from peripheral blood or spleen. Intervirology. 2011;54(1):17\u201324.","journal-title":"Intervirology"},{"key":"859_CR27","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12985-015-0256-x","volume":"12","author":"C Yang","year":"2015","unstructured":"Yang C, Ruan P, Ou C, Su J, Cao J, Luo C, et al. Chronic hepatitis B virus infection and occurrence of hepatocellular carcinoma in tree shrews (Tupaia belangeri chinensis). Virol J. 2015;12:26.","journal-title":"Virol J"},{"key":"859_CR28","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/ncomms2416","volume":"4","author":"Y Fan","year":"2013","unstructured":"Fan Y, Huang ZY, Cao CC, Chen CS, Chen YX, Fan DD, et al. Genome of the Chinese tree shrew. Nat Commun. 2013;4:1426.","journal-title":"Nat Commun"},{"issue":"9","key":"859_CR29","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s13238-012-2039-0","volume":"3","author":"R Li","year":"2012","unstructured":"Li R, Xu W, Wang Z, Liang B, Wu JR, Zeng R. Proteomic characteristics of the liver and skeletal muscle in the Chinese tree shrew (Tupaia belangeri chinensis). Protein Cell. 2012;3(9):691\u2013700.","journal-title":"Protein Cell"},{"issue":"3","key":"859_CR30","first-page":"148","volume":"3","author":"MY Zhan","year":"1981","unstructured":"Zhan MY, Liu CB, Li CM, Zhang WY, Zhu C, Pang QF, et al. A preliminary study of hepatitis A virus in Chinese tupaia (author's transl). Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1981;3(3):148\u201352.","journal-title":"Zhongguo Yi Xue Ke Xue Yuan Xue Bao"},{"key":"859_CR31","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1743-422X-9-170","volume":"9","author":"Q Wang","year":"2012","unstructured":"Wang Q, Schwarzenberger P, Yang F, Zhang J, Su J, Yang C, et al. Experimental chronic hepatitis B infection of neonatal tree shrews (Tupaia belangeri chinensis): a model to study molecular causes for susceptibility and disease progression to chronic hepatitis in humans. Virol J. 2012;9:170.","journal-title":"Virol J"},{"issue":"1","key":"859_CR32","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1128\/JVI.01448-09","volume":"84","author":"Y Amako","year":"2010","unstructured":"Amako Y, Tsukiyama-Kohara K, Katsume A, Hirata Y, Sekiguchi S, Tobita Y, et al. Pathogenesis of hepatitis C virus infection in Tupaia belangeri. J Virol. 2010;84(1):303\u201311.","journal-title":"J Virol"},{"issue":"2","key":"859_CR33","first-page":"85","volume":"96","author":"QF Pang","year":"1983","unstructured":"Pang QF, Liu JC, Wan XB, Qiu FX, Xu AY. Experimental infection of adult Tupaia belangeri yunalis with human rotavirus. Chin Med J. 1983;96(2):85\u201394.","journal-title":"Chin Med J"},{"issue":"11","key":"859_CR34","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.2460\/javma.1984.185.11.1363","volume":"185","author":"TR Schoeb","year":"1984","unstructured":"Schoeb TR, DaRif CA. Adenoviral infection in infant tree shrews. J Am Vet Med Assoc. 1984;185(11):1363\u20136.","journal-title":"J Am Vet Med Assoc"},{"issue":"2","key":"859_CR35","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1128\/JVI.02258-15","volume":"90","author":"L Li","year":"2015","unstructured":"Li L, Li Z, Wang E, Yang R, Xiao Y, Han H, et al. Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System. J Virol. 2015;90(2):790\u2013804.","journal-title":"J Virol"},{"issue":"1","key":"859_CR36","first-page":"1","volume":"33","author":"SA Li","year":"2012","unstructured":"Li SA, Lee WH, Zhang Y. Two bacterial infection models in tree shrew for evaluating the efficacy of antimicrobial agents. Dongwuxue Yanjiu. 2012;33(1):1\u20136.","journal-title":"Dongwuxue Yanjiu"},{"issue":"3","key":"859_CR37","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1167\/iovs.11-7859","volume":"53","author":"NA McBrien","year":"2012","unstructured":"McBrien NA, Arumugam B, Metlapally S. The effect of daily transient +4 D positive lens wear on the inhibition of myopia in the tree shrew. Invest Ophthalmol Vis Sci. 2012;53(3):1593\u2013601.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"859_CR38","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/jpn.12036","volume":"97","author":"X Wu","year":"2013","unstructured":"Wu X, Chang Q, Zhang Y, Zou X, Chen L, Zhang L, et al. Relationships between body weight, fasting blood glucose concentration, sex and age in tree shrews (Tupaia belangeri chinensis). J Anim Physiol Anim Nutr (Berl). 2013;97(6):1179\u201388.","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"issue":"2","key":"859_CR39","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/(SICI)1096-8652(199610)53:2<111::AID-AJH8>3.0.CO;2-2","volume":"53","author":"M Okano","year":"1996","unstructured":"Okano M, Gross TG. Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996;53(2):111\u20135.","journal-title":"Am J Hematol"},{"issue":"9","key":"859_CR40","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1038\/sj.onc.1210240","volume":"26","author":"E Klein","year":"2007","unstructured":"Klein E, Kis LL, Klein G. Epstein-Barr virus infection in humans: from harmless to life endangering virus-lymphocyte interactions. Oncogene. 2007;26(9):1297\u2013305.","journal-title":"Oncogene"},{"issue":"9","key":"859_CR41","doi-asserted-by":"crossref","first-page":"4766","DOI":"10.1128\/JVI.02608-06","volume":"81","author":"GJ MacArthur","year":"2007","unstructured":"MacArthur GJ, Wilson AD, Birchall MA, Morgan AJ. Primary CD4+ T-cell responses provide both helper and cytotoxic functions during Epstein-Barr virus infection and transformation of fetal cord blood B cells. J Virol. 2007;81(9):4766\u201375.","journal-title":"J Virol"},{"issue":"3","key":"859_CR42","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1182\/blood-2007-06-093278","volume":"111","author":"V Hadinoto","year":"2008","unstructured":"Hadinoto V, Shapiro M, Greenough TC, Sullivan JL, Luzuriaga K, Thorley-Lawson DA. On the dynamics of acute EBV infection and the pathogenesis of infectious mononucleosis. Blood. 2008;111(3):1420\u20137.","journal-title":"Blood"},{"issue":"4","key":"859_CR43","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/sj.bjc.6602968","volume":"94","author":"Y Zhang","year":"2006","unstructured":"Zhang Y, Ohyashiki JH, Takaku T, Shimizu N, Ohyashiki K. Transcriptional profiling of Epstein-Barr virus (EBV) genes and host cellular genes in nasal NK\/T-cell lymphoma and chronic active EBV infection. Br J Cancer. 2006;94(4):599\u2013608.","journal-title":"Br J Cancer"},{"issue":"5\u20136","key":"859_CR44","first-page":"223","volume":"47","author":"G Bauer","year":"2001","unstructured":"Bauer G. Simplicity through complexity: immunoblot with recombinant antigens as the new gold standard in Epstein-Barr virus serology. Clin Lab. 2001;47(5\u20136):223\u201330.","journal-title":"Clin Lab"},{"issue":"38","key":"859_CR45","doi-asserted-by":"crossref","first-page":"41033","DOI":"10.18632\/oncotarget.5708","volume":"6","author":"L Zuo","year":"2015","unstructured":"Zuo L, Yu H, Liu L, Tang Y, Wu H, Yang J, et al. The copy number of Epstein-Barr virus latent genome correlates with the oncogenicity by the activation level of LMP1 and NF-kappaB. Oncotarget. 2015;6(38):41033\u201344.","journal-title":"Oncotarget"},{"issue":"1","key":"859_CR46","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/rmv.441","volume":"15","author":"T Tsurumi","year":"2005","unstructured":"Tsurumi T, Fujita M, Kudoh A. Latent and lytic Epstein-Barr virus replication strategies. Rev Med Virol. 2005;15(1):3\u201315.","journal-title":"Rev Med Virol"},{"key":"859_CR47","unstructured":"Schillinger M, Kampmann M, Henninger K, Murray G, Hanselmann I,Bauer G. Variability of humoral immune response to acute Epstein-Barr virus (EBV) infection: Evaluation of the significance of serological markers."},{"issue":"2","key":"859_CR48","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1073\/pnas.84.2.570","volume":"84","author":"W Henle","year":"1987","unstructured":"Henle W, Henle G, Andersson J, Ernberg I, Klein G, Horwitz CA, et al. Antibody responses to Epstein-Barr virus-determined nuclear antigen (EBNA)-1 and EBNA-2 in acute and chronic Epstein-Barr virus infection. Proc Natl Acad Sci U S A. 1987;84(2):570\u20134.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"859_CR49","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/(SICI)1096-9896(199902)187:3<326::AID-PATH242>3.0.CO;2-N","volume":"187","author":"I Araujo","year":"1999","unstructured":"Araujo I, Foss HD, Hummel M, Anagnostopoulos I, Barbosa HS, Bittencourt A, et al. Frequent expansion of Epstein-Barr virus (EBV) infected cells in germinal centres of tonsils from an area with a high incidence of EBV-associated lymphoma. J Pathol. 1999;187(3):326\u201330.","journal-title":"J Pathol"},{"issue":"8","key":"859_CR50","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1073\/pnas.2627966100","volume":"100","author":"J Kurth","year":"2003","unstructured":"Kurth J, Hansmann ML, Rajewsky K, Kuppers R. Epstein-Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction. Proc Natl Acad Sci U S A. 2003;100(8):4730\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"859_CR51","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1002\/ijc.23685","volume":"123","author":"DP Dittmer","year":"2008","unstructured":"Dittmer DP, Hilscher CJ, Gulley ML, Yang EV, Chen M, Glaser R. Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinoma. Int J Cancer. 2008;123(9):2105\u201312.","journal-title":"Int J Cancer"},{"issue":"19","key":"859_CR52","doi-asserted-by":"crossref","first-page":"9628","DOI":"10.1128\/JVI.00622-06","volume":"80","author":"SM Turk","year":"2006","unstructured":"Turk SM, Jiang R, Chesnokova LS, Hutt-Fletcher LM. Antibodies to gp350\/220 enhance the ability of Epstein-Barr virus to infect epithelial cells. J Virol. 2006;80(19):9628\u201333.","journal-title":"J Virol"},{"issue":"5","key":"859_CR53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001338","volume":"7","author":"C Shannon-Lowe","year":"2011","unstructured":"Shannon-Lowe C, Rowe M. Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection. PLoS Pathog. 2011;7(5):e1001338.","journal-title":"PLoS Pathog"},{"issue":"19","key":"859_CR54","doi-asserted-by":"crossref","first-page":"7201","DOI":"10.1073\/pnas.0602077103","volume":"103","author":"GW Bornkamm","year":"2006","unstructured":"Bornkamm GW, Behrends U, Mautner J. The infectious kiss: newly infected B cells deliver Epstein-Barr virus to epithelial cells. Proc Natl Acad Sci U S A. 2006;103(19):7201\u20132.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"859_CR55","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.virol.2006.09.047","volume":"359","author":"J Xiao","year":"2007","unstructured":"Xiao J, Palefsky JM, Herrera R, Tugizov SM. Characterization of the Epstein-Barr virus glycoprotein BMRF-2. Virology. 2007;359(2):382\u201396.","journal-title":"Virology"},{"issue":"2","key":"859_CR56","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.str.2008.12.010","volume":"17","author":"AN Kirschner","year":"2009","unstructured":"Kirschner AN, Sorem J, Longnecker R, Jardetzky TS. Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry. Structure. 2009;17(2):223\u201333.","journal-title":"Structure"},{"key":"859_CR57","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.virol.2014.04.016","volume":"458-459","author":"W Jin","year":"2014","unstructured":"Jin W, Li C, Du T, Hu K, Huang X, Hu Q. DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer. Virology. 2014;458-459:83\u201392.","journal-title":"Virology"},{"key":"859_CR58","doi-asserted-by":"crossref","unstructured":"Hui-Yuen J, McAllister S, Koganti S, Hill E, Bhaduri-McIntosh S. Establishment of Epstein-Barr virus growth-transformed lymphoblastoid cell lines. J Vis Exp. 2011;57","DOI":"10.3791\/3321"},{"issue":"4","key":"859_CR59","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/S1525-1578(10)60535-1","volume":"6","author":"JL Ryan","year":"2004","unstructured":"Ryan JL, Fan H, Glaser SL, Schichman SA, Raab-Traub N, Gulley ML. Epstein-Barr virus quantitation by real-time PCR targeting multiple gene segments: a novel approach to screen for the virus in paraffin-embedded tissue and plasma. J Mol Diagn. 2004;6(4):378\u201385.","journal-title":"J Mol Diagn"},{"issue":"22","key":"859_CR60","doi-asserted-by":"crossref","first-page":"12250","DOI":"10.1073\/pnas.200366597","volume":"97","author":"GJ Babcock","year":"2000","unstructured":"Babcock GJ, Thorley-Lawson DA. Tonsillar memory B cells, latently infected with Epstein-Barr virus, express the restricted pattern of latent genes previously found only in Epstein-Barr virus-associated tumors. Proc Natl Acad Sci U S A. 2000;97(22):12250\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"859_CR61","volume":"9","author":"D Yu","year":"2014","unstructured":"Yu D, Xu L, Liu XH, Fan Y, Lu LB, Yao YG. Diverse interleukin-7 mRNA transcripts in Chinese tree shrew (Tupaia belangeri chinensis). PLoS One. 2014;9(6):e99859.","journal-title":"PLoS One"},{"issue":"7","key":"859_CR62","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1136\/jcp.45.7.616","volume":"45","author":"G Khan","year":"1992","unstructured":"Khan G, Coates PJ, Kangro HO, Slavin G. Epstein Barr virus (EBV) encoded small RNAs: targets for detection by in situ hybridisation with oligonucleotide probes. J Clin Pathol. 1992;45(7):616\u201320.","journal-title":"J Clin Pathol"},{"issue":"4","key":"859_CR63","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/00019606-199203000-00037","volume":"1","author":"KL Chang","year":"1992","unstructured":"Chang KL, Chen YY, Shibata D, Weiss LM. Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues. Diagn Mol Pathol. 1992;1(4):246\u201355.","journal-title":"Diagn Mol Pathol"},{"key":"859_CR64","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/978-1-59745-447-6_13","volume":"511","author":"G Khan","year":"2009","unstructured":"Khan G. Screening for Epstein-Barr virus in Hodgkin's lymphoma. Methods Mol Biol. 2009;511:311\u201322.","journal-title":"Methods Mol Biol"}],"container-title":["Virology Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-017-0859-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T21:14:29Z","timestamp":1750886069000},"score":1,"resource":{"primary":{"URL":"http:\/\/virologyj.biomedcentral.com\/articles\/10.1186\/s12985-017-0859-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,6]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["859"],"URL":"https:\/\/doi.org\/10.1186\/s12985-017-0859-5","relation":{},"ISSN":["1743-422X"],"issn-type":[{"value":"1743-422X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,6]]},"article-number":"193"}}