{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T16:19:05Z","timestamp":1772209145171,"version":"3.50.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,10,29]],"date-time":"2019-10-29T00:00:00Z","timestamp":1572307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Affiliated Hospital of Zunyi Medical University","award":["201808"],"award-info":[{"award-number":["201808"]}]},{"name":"Zunyi Medical University","award":["ZKDC2018017"],"award-info":[{"award-number":["ZKDC2018017"]}]},{"DOI":"10.13039\/501100010828","name":"Department of Education of Guizhou Province","doi-asserted-by":"publisher","award":["20195201909"],"award-info":[{"award-number":["20195201909"]}],"id":[{"id":"10.13039\/501100010828","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Human papillomavirus (HPV) is one of the most common sexually transmitted viruses. Data about HPV infection in Guizhou is limited.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>56,768 cervical samples were collected and genotyped for 15 main high risk and 6 main low risk HPV types.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>16.95% (9623\/56768) of samples were HPV positive; 90.70% (8728\/9623) of HPV positive women were infected by high risk HPV. High risk and high risk mix infection (1458; 70.85%) was the most common mix HPV infection type. The highest HPV detection rate was found in age group 41\u201345\u2009years old (detection rate\u2009=\u200917.89%) (\u03c72\u2009=\u2009204.77; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001); the highest within-group HPV infection rates were found in the \u226420 (25.62%) and\u2009\u2265\u200961 (24.67%) years old age groups, the lowest within-group HPV infection rate was found in the 31\u201335\u2009years old age group (15.02%). The highest mix infection proportions were found in the \u226561 (36.06%) and\u2009\u2264\u200920 (33.63%) years old age groups (\u03c72\u2009=\u2009111.21; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), the lowest mix infection proportion was found in the 41\u201345 (17.42%) years old age group. The highest high risk infection proportions were found in the 26\u201330 (92.98%), \u226561 (92.68%), and 36\u201340 (92.16%) years old age groups (\u03c72\u2009=\u200931.72; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), the lowest high risk infection proportion was found in the \u226420 (84.96%) years old age group. HPV infection rates varied with seasons in Guizhou.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Characteristics of HPV distribution in Guizhou were identified. There were significant differences in HPV distribution among age groups, prevention strategies should be adjusted according to the characteristics.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12985-019-1239-0","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T20:44:07Z","timestamp":1572468247000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Characteristics of human papillomaviruses distribution in Guizhou Province, China"],"prefix":"10.1186","volume":"16","author":[{"given":"Zuyi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiongyao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongwu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengyuan","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingfang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,29]]},"reference":[{"issue":"1","key":"1239_CR1","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1186\/s12985-016-0594-3","volume":"13","author":"TR Martins","year":"2016","unstructured":"Martins TR, de Oliveira CM, Rosa LR, et al. 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Before sample collection, a written informed consent was obtained from all the patients or their guardians, and patient\/study subject privacy was carefully protected.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"123"}}