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Serological studies have shown that these viruses are ubiquitous in the healthy adult population with seroprevalence up to 88% for HPyV6 and 72% for HPyV7. Both viruses are associated with pruritic skin eruption in immunocompromised patients, but a role with other diseases in immunoincompetent patients or malignancies has not been established.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>PCR was used to determine the presence of HPyV6 and HPyV7 DNA in urine samples from systemic lupus erythematosus (n\u2009=\u200973), multiple sclerosis (n\u2009=\u200950), psoriasis vulgaris (n\u2009=\u200915), arthritic psoriasis (n\u2009=\u200915) and HIV-positive patients (n\u2009=\u200966). In addition, urine from pregnant women (n\u2009=\u200947) and healthy blood donors (n\u2009=\u200920) was investigated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>HPyV6 DNA was detected in 21 (28.8%) of the urine specimens from SLE patients, in 6 (9.1%) of the urine samples from the HIV-positive cohort, and in 19 (40.4%) samples from pregnant women. HPyV7 DNA was only found in 6 (8.2%) of the urine specimens from SLE patients and in 4 (8.5%) samples from pregnant women. No HPyV6 and HPyV7 viruria was detected in the urine samples from the other patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>HPyV6, and to a lesser extend HPyV7, viruria seems to be common in SLE and HIV-positive patients, and pregnant women. Whether these viruses are of clinical relevance in these patients is not known.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12985-021-01496-1","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T08:03:37Z","timestamp":1611302617000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["HPyV6 and HPyV7 in urine from immunocompromised patients"],"prefix":"10.1186","volume":"18","author":[{"given":"Carla","family":"Prezioso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijke","family":"Van Ghelue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1931-5462","authenticated-orcid":false,"given":"Ugo","family":"Moens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Pietropaolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,22]]},"reference":[{"key":"1496_CR1","doi-asserted-by":"publisher","first-page":"414","DOI":"10.3181\/00379727-83-20376","volume":"83","author":"L Gross","year":"1953","unstructured":"Gross L. 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