{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:56:50Z","timestamp":1765486610533},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Kerman Branch, Islamic Azad University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>It has been reported that polyomaviruses are the microbes which can be a cause of several human pathological conditions including cancers, nephropathy, progressive multifocal leukoencephalopathy and gynaecological disease. Although investigators proposed some mechanisms used by the viruses to induce the disorders, the roles played by chemokines in the pathogenesis of polyomaviruses infections are yet to be clarified. This review article investigated recent studies regarding the roles played by chemokines in the pathogenesis of the polyomaviruses infections. The research in the literature revealed that CXC chemokines, including CXCL1, CXCL5, CXCL8, CXCL9, CXCL10, CXCL11, CXCL12 and CXCL16, significantly participate in the pathogenesis of polyomaviruses. CC chemokines, such as CCL2, CCL5 and CCL20 also participate in the induction of the pathological conditions. Therefore, it appears that CXC chemokines may be considered as the strategic factors involved in the pathogenesis of polyomaviruses.<\/jats:p>","DOI":"10.1186\/s12985-021-01582-4","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T08:03:03Z","timestamp":1622707383000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["CC and CXC chemokines play key roles in the development of polyomaviruses related pathological conditions"],"prefix":"10.1186","volume":"18","author":[{"given":"Mohammad Hassan","family":"Mohammadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraf","family":"Kariminik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"issue":"6","key":"1582_CR1","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1002\/rmv.1711","volume":"22","author":"M Van Ghelue","year":"2012","unstructured":"Van Ghelue M, Khan MT, Ehlers B, Moens U. Genome analysis of the new human polyomaviruses. Rev Med Virol. 2012;22(6):354\u201377.","journal-title":"Rev Med Virol"},{"key":"1582_CR2","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.cyto.2016.09.023","volume":"88","author":"A Kariminik","year":"2016","unstructured":"Kariminik A. IL-2 and polyoma BK virus infection; a systematic review article. Cytokine. 2016;88:276\u201380.","journal-title":"Cytokine"},{"key":"1582_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/0-387-32957-9_1","volume":"577","author":"N Ahsan","year":"2006","unstructured":"Ahsan N, Shah KV. Polyomaviruses and human diseases. Adv Exp Med Biol. 2006;577:1\u201318.","journal-title":"Adv Exp Med Biol"},{"issue":"1","key":"1582_CR4","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.brainresrev.2005.04.007","volume":"50","author":"MK White","year":"2005","unstructured":"White MK, Gordon J, Reiss K, Del Valle L, Croul S, Giordano A, et al. Human polyomaviruses and brain tumors. Brain Res Brain Res Rev. 2005;50(1):69\u201385.","journal-title":"Brain Res Brain Res Rev"},{"issue":"2","key":"1582_CR5","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1089\/vim.2015.0099","volume":"29","author":"A Kariminik","year":"2016","unstructured":"Kariminik A, Yaghobi R, Dabiri S. Innate immunity and BK virus: prospective strategies. Viral Immunol. 2016;29(2):74\u201382.","journal-title":"Viral Immunol"},{"issue":"11","key":"1582_CR6","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1089\/wound.2014.0594","volume":"4","author":"RJ Bodnar","year":"2015","unstructured":"Bodnar RJ. Chemokine regulation of angiogenesis during wound healing. Adv Wound Care (New Rochelle). 2015;4(11):641\u201350.","journal-title":"Adv Wound Care (New Rochelle)"},{"issue":"1","key":"1582_CR7","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.virol.2009.11.029","volume":"398","author":"MR Myhre","year":"2010","unstructured":"Myhre MR, Olsen G-H, Gosert R, Hirsch HH, Rinaldo CH. Clinical polyomavirus BK variants with agnogene deletion are non-functional but rescued by trans-complementation. Virology. 2010;398(1):12\u201320.","journal-title":"Virology"},{"key":"1582_CR8","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.cyto.2017.02.011","volume":"95","author":"A Kariminik","year":"2017","unstructured":"Kariminik A, Kheirkhah B. Tumor growth factor-beta is an important factor for immunosuppression and tumorgenesis in Polyoma BK virus infection; a systematic review article. Cytokine. 2017;95:64\u20139.","journal-title":"Cytokine"},{"issue":"16","key":"1582_CR9","doi-asserted-by":"publisher","first-page":"8593","DOI":"10.1128\/JVI.78.16.8593-8600.2004","volume":"78","author":"A Darbinyan","year":"2004","unstructured":"Darbinyan A, Siddiqui KM, Slonina D, Darbinian N, Amini S, White MK, et al. Role of JC virus agnoprotein in DNA repair. J Virol. 2004;78(16):8593\u2013600.","journal-title":"J Virol"},{"issue":"3","key":"1582_CR10","doi-asserted-by":"publisher","first-page":"902","DOI":"10.3390\/ijms19030902","volume":"19","author":"MM Panou","year":"2018","unstructured":"Panou MM, Prescott EL, Hurdiss DL, Swinscoe G, Hollinshead M, Caller LG, et al. Agnoprotein is an essential egress factor during BK polyomavirus infection. Int J Mol Sci. 2018;19(3):902.","journal-title":"Int J Mol Sci"},{"issue":"5","key":"1582_CR11","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.semnephrol.2016.05.014","volume":"36","author":"J Trofe-Clark","year":"2016","unstructured":"Trofe-Clark J, Sawinski D. BK and other polyomaviruses in kidney transplantation. Semin Nephrol. 2016;36(5):372\u201385.","journal-title":"Semin Nephrol"},{"issue":"2","key":"1582_CR12","first-page":"167","volume":"67","author":"B Padilla-Fernandez","year":"2014","unstructured":"Padilla-Fernandez B, Bastida-Bermejo J, Virseda-Rodriguez A, Labrador-Gomez J, Caballero-Barrigon D, Silva-Abuin J, et al. Hemorrhagic cytitis after bone marrow transplantation. Arch Esp Urol. 2014;67(2):167\u201374.","journal-title":"Arch Esp Urol"},{"issue":"3","key":"1582_CR13","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1093\/ndt\/gfs537","volume":"28","author":"SG Sharma","year":"2013","unstructured":"Sharma SG, Nickeleit V, Herlitz LC, de Gonzalez AK, Stokes MB, Singh HK, et al. BK polyoma virus nephropathy in the native kidney. Nephrol Dial Transplant. 2013;28(3):620\u201331.","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"1582_CR14","first-page":"405","volume":"9","author":"E Shakiba","year":"2011","unstructured":"Shakiba E, Yaghobi R, Ramzi M. Prevalence of viral infections and hemorrhagic cystitis in hematopoietic stem cell transplant recipients. Exp Clin Transplant. 2011;9(6):405\u201312.","journal-title":"Exp Clin Transplant"},{"key":"1582_CR15","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/0-387-32957-9_2","volume":"577","author":"WA Knowles","year":"2006","unstructured":"Knowles WA. Discovery and epidemiology of the human polyomaviruses BK virus (BKV) and JC virus (JCV). Adv Exp Med Biol. 2006;577:19\u201345.","journal-title":"Adv Exp Med Biol"},{"issue":"4","key":"1582_CR16","first-page":"172","volume":"70","author":"M Van Aalderen","year":"2012","unstructured":"Van Aalderen M, Heutinck K, Huisman C, Ten Berge I. BK virus infection in transplant recipients: clinical manifestations, treatment options and the immune response. Neth J Med. 2012;70(4):172\u201383.","journal-title":"Neth J Med"},{"issue":"20","key":"1582_CR17","doi-asserted-by":"publisher","first-page":"E4040","DOI":"10.1073\/pnas.1703879114","volume":"114","author":"HJ Kwun","year":"2017","unstructured":"Kwun HJ, Chang Y, Moore PS. Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence. Proc Natl Acad Sci U S A. 2017;114(20):E4040\u20137.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"1582_CR18","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1002\/jmv.21605","volume":"81","author":"GH Olsen","year":"2009","unstructured":"Olsen GH, Hirsch HH, Rinaldo CH. Functional analysis of polyomavirus BK non-coding control region quasispecies from kidney transplant recipients. J Med Virol. 2009;81(11):1959\u201367.","journal-title":"J Med Virol"},{"issue":"3","key":"1582_CR19","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/jmv.20551","volume":"78","author":"GH Olsen","year":"2006","unstructured":"Olsen GH, Andresen PA, Hilmarsen HT, Bj\u00f8rang O, Scott H, Midtvedt K, et al. Genetic variability in BK Virus regulatory regions in urine and kidney biopsies from renal-transplant patients. J Med Virol. 2006;78(3):384\u201393.","journal-title":"J Med Virol"},{"issue":"2","key":"1582_CR20","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.virol.2011.10.026","volume":"422","author":"NM Broekema","year":"2012","unstructured":"Broekema NM, Imperiale MJ. Efficient propagation of archetype BK and JC polyomaviruses. Virology. 2012;422(2):235\u201341.","journal-title":"Virology"},{"issue":"9","key":"1582_CR21","doi-asserted-by":"publisher","first-page":"2923","DOI":"10.1016\/j.transproceed.2006.08.177","volume":"38","author":"B Geramizadeh","year":"2006","unstructured":"Geramizadeh B, Roozbeh J, Malek-Hosseini S-A, Azarpira N, Ayatollahi M, Salahi H, et al. Urine cytology as a useful screening method for polyoma virus nephropathy in renal transplant patients: a single-center experience. Transplant Proc. 2006;38(9):2923\u20135.","journal-title":"Transplant Proc"},{"issue":"3","key":"1582_CR22","doi-asserted-by":"publisher","first-page":"e16738","DOI":"10.5812\/jjm.16738","volume":"8","author":"GA Kaydani","year":"2015","unstructured":"Kaydani GA, Makvandi M, Samarbafzadeh A, Shahbazian H, Fard MH. Prevalence and distribution of BK virus subtypes in renal transplant recipients referred to golestan hospital in Ahvaz, Iran. Jundishapur J Microbiol. 2015;8(3):e16738.","journal-title":"Jundishapur J Microbiol"},{"issue":"2","key":"1582_CR23","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1053\/ajkd.2001.26101","volume":"38","author":"FK Baksh","year":"2001","unstructured":"Baksh FK, Finkelstein SD, Swalsky PA, Stoner GL, Ryschkewitsch CF, Randhawa P. Molecular genotyping of BK and JC viruses in human polyomavirus [ndash] associated interstitial nephritis after renal transplantation. Am J Kidney Dis. 2001;38(2):354\u201365.","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"1582_CR24","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1002\/rmv.428","volume":"14","author":"Y Yogo","year":"2004","unstructured":"Yogo Y, Sugimoto C, Zheng HY, Ikegaya H, Takasaka T, Kitamura T. JC virus genotyping offers a new paradigm in the study of human populations. Rev Med Virol. 2004;14(3):179\u201391.","journal-title":"Rev Med Virol"},{"issue":"8","key":"1582_CR25","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1111\/apm.12128","volume":"121","author":"HH Hirsch","year":"2013","unstructured":"Hirsch HH, Kardas P, Kranz D, Leboeuf C. The human JC polyomavirus (JCPyV): virological background and clinical implications. APMIS. 2013;121(8):685\u2013727.","journal-title":"APMIS"},{"issue":"4","key":"1582_CR26","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1002\/rmv.613","volume":"19","author":"Y Yogo","year":"2009","unstructured":"Yogo Y, Sugimoto C, Zhong S, Homma Y. Evolution of the BK polyomavirus: epidemiological, anthropological and clinical implications. Rev Med Virol. 2009;19(4):185\u201399.","journal-title":"Rev Med Virol"},{"issue":"5","key":"1582_CR27","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1099\/vir.0.028571-0","volume":"92","author":"R Boldorini","year":"2011","unstructured":"Boldorini R, Allegrini S, Miglio U, Paganotti A, Cocca N, Zaffaroni M, et al. Serological evidence of vertical transmission of JC and BK polyomaviruses in humans. J Gen Virol. 2011;92(5):1044\u201350.","journal-title":"J Gen Virol"},{"issue":"10","key":"1582_CR28","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1007\/s00467-010-1716-6","volume":"26","author":"VR Dharnidharka","year":"2011","unstructured":"Dharnidharka VR, Abdulnour HA, Araya CE. The BK virus in renal transplant recipients\u2014review of pathogenesis, diagnosis, and treatment. Pediatr Nephrol. 2011;26(10):1763\u201374.","journal-title":"Pediatr Nephrol"},{"issue":"1","key":"1582_CR29","first-page":"59","volume":"8","author":"M Portolani","year":"1985","unstructured":"Portolani M, Piani M, Gazzanelli G, Borgatti M, Bartoletti A, Grossi M, et al. Restricted replication of BK virus in human lymphocytes. Microbiologica. 1985;8(1):59\u201366.","journal-title":"Microbiologica"},{"key":"1582_CR30","unstructured":"Hirsch HH. Virology, epidemiology, and pathogenesis of JC polyomavirus, BK polyomavirus, and other human polyomaviruses. UpToDate. 2019."},{"issue":"1","key":"1582_CR31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1186\/s12885-017-3817-0","volume":"17","author":"D Gao","year":"2017","unstructured":"Gao D, Cazares LH, Fish EN. CCL5-CCR5 interactions modulate metabolic events during tumor onset to promote tumorigenesis. BMC Cancer. 2017;17(1):834.","journal-title":"BMC Cancer"},{"issue":"12","key":"1582_CR32","doi-asserted-by":"publisher","first-page":"856","DOI":"10.2533\/chimia.2016.856","volume":"70","author":"DF Legler","year":"2016","unstructured":"Legler DF, Thelen M. Chemokines: chemistry, biochemistry and biological function. Chimia (Aarau). 2016;70(12):856\u20139.","journal-title":"Chimia (Aarau)"},{"issue":"5","key":"1582_CR33","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.dci.2003.09.006","volume":"28","author":"KJ Laing","year":"2004","unstructured":"Laing KJ, Secombes CJ. Chemokines. Dev Comp Immunol. 2004;28(5):443\u201360.","journal-title":"Dev Comp Immunol"},{"issue":"5","key":"1582_CR34","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1189\/jlb.4RU0417-145RR","volume":"102","author":"SM Pontejo","year":"2017","unstructured":"Pontejo SM, Murphy PM. Chemokines encoded by herpesviruses. J Leukoc Biol. 2017;102(5):1199\u2013217.","journal-title":"J Leukoc Biol"},{"issue":"1","key":"1582_CR35","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.pharmthera.2006.04.002","volume":"112","author":"C Bizzarri","year":"2006","unstructured":"Bizzarri C, Beccari AR, Bertini R, Cavicchia MR, Giorgini S, Allegretti M. ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets. Pharmacol Ther. 2006;112(1):139\u201349.","journal-title":"Pharmacol Ther"},{"issue":"3","key":"1582_CR36","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.micinf.2011.10.003","volume":"14","author":"Y Lei","year":"2012","unstructured":"Lei Y, Takahama Y. XCL1 and XCR1 in the immune system. Microbes Infect. 2012;14(3):262\u20137.","journal-title":"Microbes Infect"},{"issue":"5","key":"1582_CR37","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s00005-016-0395-9","volume":"64","author":"W Liu","year":"2016","unstructured":"Liu W, Jiang L, Bian C, Liang Y, Xing R, Yishakea M, et al. Role of CX3CL1 in diseases. Arch Immunol Ther Exp (Warsz). 2016;64(5):371\u201383.","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"issue":"2","key":"1582_CR38","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1080\/13550280590924539","volume":"11","author":"A Marzocchetti","year":"2005","unstructured":"Marzocchetti A, Cingolani A, Giambenedetto SD, Ammassari A, Giancola ML, Cauda R, et al. Macrophage chemoattractant protein-1 levels in cerebrospinal fluid correlate with containment of JC virus and prognosis of acquired immunodeficiency syndrome\u2013associated progressive multifocal leukoencephalopathy. J Neurovirol. 2005;11(2):219\u201324.","journal-title":"J Neurovirol"},{"issue":"6","key":"1582_CR39","doi-asserted-by":"publisher","first-page":"e0129694","DOI":"10.1371\/journal.pone.0129694","volume":"10","author":"FI De-Simone","year":"2015","unstructured":"De-Simone FI, Sariyer R, Otalora YL, Yarandi S, Craigie M, Gordon J, et al. IFN-Gamma inhibits JC virus replication in glial cells by suppressing T-antigen expression. PLoS ONE. 2015;10(6):e0129694.","journal-title":"PLoS ONE"},{"issue":"11","key":"1582_CR40","doi-asserted-by":"publisher","first-page":"3060","DOI":"10.1002\/jcp.25723","volume":"232","author":"C Cason","year":"2017","unstructured":"Cason C, Campisciano G, Zanotta N, Valencic E, Delbue S, Bella R, et al. SV40 infection of mesenchymal stromal cells from Wharton\u2019s jelly drives the production of inflammatory and tumoral mediators. J Cell Physiol. 2017;232(11):3060\u20136.","journal-title":"J Cell Physiol"},{"issue":"12","key":"1582_CR41","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1517\/14728222.2013.837886","volume":"17","author":"RE Marques","year":"2013","unstructured":"Marques RE, Guabiraba R, Russo RC, Teixeira MM. Targeting CCL5 in inflammation. Expert Opin Ther Targets. 2013;17(12):1439\u201360.","journal-title":"Expert Opin Ther Targets"},{"issue":"1","key":"1582_CR42","first-page":"104","volume":"62","author":"A Kariminik","year":"2016","unstructured":"Kariminik A, Yaghobi R, Dabiri S. CXCL9 expression and polyomavirus BK infectivity in renal transplant patients with nephropathy. Cell Mol Biol (Noisy-le-grand). 2016;62(1):104\u20138.","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"issue":"4","key":"1582_CR43","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1007\/s10753-016-0385-4","volume":"39","author":"A Kariminik","year":"2016","unstructured":"Kariminik A, Dabiri S, Yaghobi R. Polyomavirus BK induces inflammation via up-regulation of CXCL10 at translation levels in renal transplant patients with nephropathy. Inflammation. 2016;39(4):1514\u20139.","journal-title":"Inflammation"},{"issue":"1","key":"1582_CR44","first-page":"50","volume":"16","author":"A Kariminik","year":"2018","unstructured":"Kariminik A, Yaghobi R, Dabiri S. Association of BK virus infection with CXCL11 gene expression and protein levels in kidney transplant patients. Exp Clin Transplant. 2018;16(1):50\u20134.","journal-title":"Exp Clin Transplant"},{"issue":"1","key":"1582_CR45","doi-asserted-by":"publisher","first-page":"e1007505","DOI":"10.1371\/journal.ppat.1007505","volume":"15","author":"P An","year":"2019","unstructured":"An P, S\u00e1enz Robles MT, Duray AM, Cantalupo PG, Pipas JM. Human polyomavirus BKV infection of endothelial cells results in interferon pathway induction and persistence. PLoS Pathog. 2019;15(1):e1007505.","journal-title":"PLoS Pathog"},{"issue":"3","key":"1582_CR46","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/tri.12251","volume":"27","author":"T Schachtner","year":"2014","unstructured":"Schachtner T, Stein M, Sefrin A, Babel N, Reinke P. Inflammatory activation and recovering BKV-specific immunity correlate with self-limited BKV replication after renal transplantation. Transpl Int. 2014;27(3):290\u2013301.","journal-title":"Transpl Int"},{"issue":"10","key":"1582_CR47","doi-asserted-by":"publisher","first-page":"2228","DOI":"10.1111\/j.1600-6143.2011.03680.x","volume":"11","author":"JA Jackson","year":"2011","unstructured":"Jackson JA, Kim EJ, Begley B, Cheeseman J, Harden T, Perez SD, et al. Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection. Am J Transplant. 2011;11(10):2228\u201334.","journal-title":"Am J Transplant"},{"issue":"7","key":"1582_CR48","doi-asserted-by":"publisher","first-page":"3195","DOI":"10.4049\/jimmunol.168.7.3195","volume":"168","author":"JH Dufour","year":"2002","unstructured":"Dufour JH, Dziejman M, Liu MT, Leung JH, Lane TE, Luster AD. IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol. 2002;168(7):3195\u2013204.","journal-title":"J Immunol"},{"issue":"1","key":"1582_CR49","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1084\/jem.182.1.155","volume":"182","author":"AL Angiolillo","year":"1995","unstructured":"Angiolillo AL, Sgadari C, Taub DD, Liao F, Farber JM, Maheshwari S, et al. Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med. 1995;182(1):155\u201362.","journal-title":"J Exp Med"},{"issue":"1","key":"1582_CR50","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1038\/ki.2011.311","volume":"81","author":"A Ribeiro","year":"2012","unstructured":"Ribeiro A, Wornle M, Motamedi N, Anders HJ, Grone EF, Nitschko H, et al. Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy. Kidney Int. 2012;81(1):100\u201311.","journal-title":"Kidney Int"},{"issue":"5","key":"1582_CR51","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.yexcr.2011.01.009","volume":"317","author":"JK Lim","year":"2011","unstructured":"Lim JK, Murphy PM. Chemokine control of West Nile virus infection. Exp Cell Res. 2011;317(5):569\u201374.","journal-title":"Exp Cell Res"},{"issue":"20","key":"1582_CR52","doi-asserted-by":"publisher","first-page":"122268","DOI":"10.1172\/jci.insight.122268","volume":"3","author":"S Yoshio","year":"2018","unstructured":"Yoshio S, Mano Y, Doi H, Shoji H, Shimagaki T, Sakamoto Y, et al. Cytokine and chemokine signatures associated with hepatitis B surface antigen loss in hepatitis B patients. JCI Insight. 2018;3(20):122268.","journal-title":"JCI Insight"},{"issue":"12","key":"1582_CR53","doi-asserted-by":"publisher","first-page":"1962","DOI":"10.1093\/infdis\/jit440","volume":"208","author":"Y Chi","year":"2013","unstructured":"Chi Y, Zhu Y, Wen T, Cui L, Ge Y, Jiao Y, et al. Cytokine and chemokine levels in patients infected with the novel avian influenza A (H7N9) virus in China. J Infect Dis. 2013;208(12):1962\u20137.","journal-title":"J Infect Dis"},{"issue":"8","key":"1582_CR54","doi-asserted-by":"publisher","first-page":"e104848","DOI":"10.1371\/journal.pone.0104848","volume":"9","author":"M Comar","year":"2014","unstructured":"Comar M, Zanotta N, Bonotti A, Tognon M, Negro C, Cristaudo A, et al. Increased levels of C-C chemokine RANTES in asbestos exposed workers and in malignant mesothelioma patients from an hyperendemic area. PLoS ONE. 2014;9(8):e104848.","journal-title":"PLoS ONE"},{"issue":"1","key":"1582_CR55","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.cyto.2013.12.011","volume":"66","author":"JL Steiner","year":"2014","unstructured":"Steiner JL, Davis JM, McClellan JL, Guglielmotti A, Murphy EA. Effects of the MCP-1 synthesis inhibitor bindarit on tumorigenesis and inflammatory markers in the C3(1)\/SV40Tag mouse model of breast cancer. Cytokine. 2014;66(1):60\u20138.","journal-title":"Cytokine"},{"issue":"2","key":"1582_CR56","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.3390\/cancers6021047","volume":"6","author":"R Wheat","year":"2014","unstructured":"Wheat R, Roberts C, Waterboer T, Steele J, Marsden J, Steven NM, et al. Inflammatory cell distribution in primary merkel cell carcinoma. Cancers (Basel). 2014;6(2):1047\u201364.","journal-title":"Cancers (Basel)"},{"issue":"5","key":"1582_CR57","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1158\/1940-6207.CAPR-11-0404","volume":"5","author":"K Tran","year":"2012","unstructured":"Tran K, Risingsong R, Royce D, Williams CR, Sporn MB, Liby K. The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice. Cancer Prev Res (Phila). 2012;5(5):726\u201334.","journal-title":"Cancer Prev Res (Phila)"},{"issue":"114","key":"1582_CR58","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.addr.2017.04.010","volume":"15","author":"C Ngambenjawong","year":"2017","unstructured":"Ngambenjawong C, Gustafson HH, Pun SH. Progress in tumor-associated macrophage (TAM)-targeted therapeutics. Adv Drug Deliv Rev. 2017;15(114):206\u201321.","journal-title":"Adv Drug Deliv Rev"},{"issue":"115","key":"1582_CR59","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/s12943-015-0394-1","volume":"14","author":"ST Boyle","year":"2015","unstructured":"Boyle ST, Faulkner JW, McColl SR, Kochetkova M. The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages. Mol Cancer. 2015;14(115):115.","journal-title":"Mol Cancer"},{"issue":"12","key":"1582_CR60","doi-asserted-by":"publisher","first-page":"3532","DOI":"10.1099\/jgv.0.000287","volume":"96","author":"KF Richards","year":"2015","unstructured":"Richards KF, Guastafierro A, Shuda M, Toptan T, Moore PS, Chang Y. Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression. J Gen Virol. 2015;96(12):3532\u201344.","journal-title":"J Gen Virol"},{"issue":"1\u20132","key":"1582_CR61","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s11010-015-2581-1","volume":"411","author":"A Ribeiro","year":"2016","unstructured":"Ribeiro A, Merkle M, Motamedi N, Nitschko H, Koppel S, Wornle M. BK virus infection activates the TNFalpha\/TNF receptor system in Polyomavirus-associated nephropathy. Mol Cell Biochem. 2016;411(1\u20132):191\u20139.","journal-title":"Mol Cell Biochem"},{"issue":"1","key":"1582_CR62","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.transproceed.2005.12.087","volume":"38","author":"M Boratynska","year":"2006","unstructured":"Boratynska M, Dubinski B, Rybka K, Jezior D, Szyber P, Klinger M. Immunocytological urinalysis and monocyte chemotactic peptide-1 in renal transplant recipients with polyomavirus replication. Transplant Proc. 2006;38(1):151\u20134.","journal-title":"Transplant Proc"},{"issue":"1","key":"1582_CR63","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jaci.2017.02.039","volume":"141","author":"E Hornsby","year":"2018","unstructured":"Hornsby E, Pfeffer PE, Laranjo N, Cruikshank W, Tuzova M, Litonjua AA, et al. Vitamin D supplementation during pregnancy: effect on the neonatal immune system in a randomized controlled trial. J Allergy Clin Immunol. 2018;141(1):269-278.e1.","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"1582_CR64","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/jnr.23135","volume":"91","author":"A Darbinyan","year":"2013","unstructured":"Darbinyan A, Kaminski R, White MK, Darbinian-Sarkissian N, Khalili K. Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells. J Neurosci Res. 2013;91(1):116\u201327.","journal-title":"J Neurosci Res"},{"issue":"8","key":"1582_CR65","doi-asserted-by":"publisher","first-page":"3119","DOI":"10.1002\/jcp.23065","volume":"227","author":"N Merabova","year":"2012","unstructured":"Merabova N, Kaminski R, Krynska B, Amini S, Khalili K, Darbinyan A. JCV agnoprotein-induced reduction in CXCL5\/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons. J Cell Physiol. 2012;227(8):3119\u201327.","journal-title":"J Cell Physiol"},{"issue":"2","key":"1582_CR66","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1046\/j.1365-2249.2002.01889.x","volume":"129","author":"XY Zhang","year":"2002","unstructured":"Zhang XY, Guckian M, Nasiri N, Lovell PA, Dalgleish AG, Barton DP. Normal and SV40 transfected human peritoneal mesothelial cells produce IL-6 and IL-8: implication for gynaecological disease. Clin Exp Immunol. 2002;129(2):288\u201396.","journal-title":"Clin Exp Immunol"},{"issue":"2","key":"1582_CR67","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/s007050050506","volume":"144","author":"K Asamitsu","year":"1999","unstructured":"Asamitsu K, Sakurada S, Mashiba K, Nakagawa K, Torikai K, Onozaki K, et al. Alteration of the cellular response to interleukin-1 beta by SV40 large T antigen in rheumatoid synovial fibroblasts. Arch Virol. 1999;144(2):317\u201327.","journal-title":"Arch Virol"},{"key":"1582_CR68","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.imlet.2016.05.018","volume":"176","author":"T Qidwai","year":"2016","unstructured":"Qidwai T. Chemokine genetic polymorphism in human health and disease. Immunol Lett. 2016;176:128\u201338.","journal-title":"Immunol Lett"},{"issue":"1","key":"1582_CR69","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.biopha.2007.04.005","volume":"62","author":"FR Guerini","year":"2008","unstructured":"Guerini FR, Delbue S, Zanzottera M, Agliardi C, Saresella M, Mancuso R, et al. Analysis of CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-related PML and not determined leukoencephalopathy. Biomed Pharmacother. 2008;62(1):26\u201330.","journal-title":"Biomed Pharmacother"}],"container-title":["Virology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-021-01582-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12985-021-01582-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-021-01582-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T12:58:45Z","timestamp":1699102725000},"score":1,"resource":{"primary":{"URL":"https:\/\/virologyj.biomedcentral.com\/articles\/10.1186\/s12985-021-01582-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,3]]},"references-count":69,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1582"],"URL":"https:\/\/doi.org\/10.1186\/s12985-021-01582-4","relation":{},"ISSN":["1743-422X"],"issn-type":[{"value":"1743-422X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,3]]},"assertion":[{"value":"13 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}},{"value":"There is no competing interest to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"111"}}