{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T22:39:41Z","timestamp":1722811181642},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Multisystem inflammatory syndrome (MIS), which develops after a past covid-19 infection. MIS can be described in different tissue inflammation, including the heart, lung, kidney, brain, skin, eye, and or gastrointestinal organs at the presence of COVID-19. Initially, MIS was described in Europe in children infected with SARS-CoV-2, then it was recently seen in the USA in 2020. MIS is a rare but serious disease condition associated with COVID-19 that can affect children (MIS-C) and adults (MIS-A).\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 44-year-old male who showed MIS-A in 59-day after his first covid-19 contact history. The patient presented to our emergency department with complaints of high fever, nausea, weakness, redness of the eyes, headache, and joint pain. On the second day of his hospitalization, a maculopapular skin lesion was seen in most of the skin. His fever could not be controlled even given paracetamol and broad effective antibiotics. His clinical, radiological, and laboratory findings showed that he had MIS-A. The patient was given intravenous pulse methylprednisolone and intravenous immunoglobulin (IVIG). These treatments, then, resulted in improvement of his clinical conditions, including fever and skin lesions, on the second day of the treatment. The patient was discharged in 14\u00a0days after the treatment.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This report indicated that diagnosis and treatment of MIS-A could result in reducing patient morbidity and mortality.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12985-021-01736-4","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T13:03:00Z","timestamp":1641474180000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Management skin manifestation of multisystem inflammatory syndrome associated with SARS-CoV-2"],"prefix":"10.1186","volume":"19","author":[{"given":"Yeter Eylul","family":"Bayram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Yildiz-Sevgi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse","family":"Yavuz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Cancetin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Yavuz","family":"Gurler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"1736_CR1","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.2147\/JMDH.S322431","volume":"14","author":"AF Aljouie","year":"2021","unstructured":"Aljouie AF, Almazroa A, Bokhari Y, Alawad M, Mahmoud E, Alawad E, et al. Early prediction of COVID-19 ventilation requirement and mortality from routinely collected baseline chest radiographs, laboratory, and clinical data with machine learning. J Multidiscip Healthc. 2021;14:2017\u201333.","journal-title":"J Multidiscip Healthc"},{"key":"1736_CR2","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.15585\/mmwr.mm6940e1","volume":"69","author":"SB Morris","year":"2020","unstructured":"Morris SB, Schwartz NG, Patel P, Abbo L, Beauchamps L, Balan S, et al. Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection - United Kingdom and United States, March-August 2020. MMWR Morb Mortal Wkly Rep. 2020;69:1450\u20136.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"1736_CR3","doi-asserted-by":"publisher","first-page":"3037","DOI":"10.1016\/j.vaccine.2021.01.054","volume":"39","author":"TP Vogel","year":"2021","unstructured":"Vogel TP, Top KA, Karatzios C, Hilmers DC, Tapia LI, Moceri P, et al. Multisystem inflammatory syndrome in children and adults (MIS-C\/A): Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2021;39:3037\u201349.","journal-title":"Vaccine"},{"key":"1736_CR4","doi-asserted-by":"crossref","unstructured":"Greenhalgh T, Knight M, A'Court C, Buxton M, Husain L. Management of post-acute covid-19 in primary care. Bmj. 2020;370:m3026.","DOI":"10.1136\/bmj.m3026"},{"key":"1736_CR5","first-page":"51","volume":"38","author":"T Radia","year":"2021","unstructured":"Radia T, Williams N, Agrawal P, Harman K, Weale J, Cook J, et al. Multi-system inflammatory syndrome in children & adolescents (MIS-C): a systematic review of clinical features and presentation. Paediatr Respir Rev. 2021;38:51\u20137.","journal-title":"Paediatr Respir Rev"},{"key":"1736_CR6","doi-asserted-by":"publisher","first-page":"680567","DOI":"10.3389\/fimmu.2021.680567","volume":"12","author":"I Boudhabhay","year":"2021","unstructured":"Boudhabhay I, Rabant M, Roumenina LT, Coupry LM, Poillerat V, Marchal A, et al. Case report: adult post-COVID-19 multisystem inflammatory syndrome and thrombotic microangiopathy. Front Immunol. 2021;12:680567.","journal-title":"Front Immunol"},{"key":"1736_CR7","doi-asserted-by":"publisher","first-page":"305","DOI":"10.14745\/ccdr.v47i78a03","volume":"47","author":"N Atchessi","year":"2021","unstructured":"Atchessi N, Edjoc R, Striha M, Waddell L, Bresee N, Dawson T. Epidemiologic and clinical characteristics of multisystem inflammatory syndrome in adults: a rapid review. Can Commun Dis Rep. 2021;47:305\u201315.","journal-title":"Can Commun Dis Rep"},{"key":"1736_CR8","doi-asserted-by":"publisher","first-page":"e2126456","DOI":"10.1001\/jamanetworkopen.2021.26456","volume":"4","author":"P Patel","year":"2021","unstructured":"Patel P, De Cuir J, Abrams J, Campbell AP, Godfred-Cato S, Belay ED. Clinical characteristics of multisystem inflammatory syndrome in adults: a systematic review. JAMA Netw Open. 2021;4:e2126456.","journal-title":"JAMA Netw Open"},{"key":"1736_CR9","doi-asserted-by":"publisher","first-page":"11","DOI":"10.2165\/00148581-200507010-00002","volume":"7","author":"YY Chuang","year":"2005","unstructured":"Chuang YY, Huang YC, Lin TY. Toxic shock syndrome in children: epidemiology, pathogenesis, and management. Paediatr Drugs. 2005;7:11\u201325.","journal-title":"Paediatr Drugs"},{"key":"1736_CR10","doi-asserted-by":"crossref","unstructured":"Gu X, Zhou F, Wang Y, Fan G, Cao B. Respiratory viral sepsis: epidemiology, pathophysiology, diagnosis and treatment. Eur Respir Rev. 2020;29.","DOI":"10.1183\/16000617.0038-2020"},{"key":"1736_CR11","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.alit.2019.03.006","volume":"68","author":"T Shiohara","year":"2019","unstructured":"Shiohara T, Mizukawa Y. Drug-induced hypersensitivity syndrome (DiHS)\/drug reaction with eosinophilia and systemic symptoms (DRESS): an update in 2019. Allergol Int. 2019;68:301\u20138.","journal-title":"Allergol Int"},{"key":"1736_CR12","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s11926-020-00941-4","volume":"22","author":"E Rife","year":"2020","unstructured":"Rife E, Gedalia A. Kawasaki disease: an update. Curr Rheumatol Rep. 2020;22:75.","journal-title":"Curr Rheumatol Rep"},{"key":"1736_CR13","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3389\/fimmu.2019.00119","volume":"10","author":"CB Crayne","year":"2019","unstructured":"Crayne CB, Albeituni S, Nichols KE, Cron RQ. The Immunology of Macrophage Activation Syndrome. Front Immunol. 2019;10:119.","journal-title":"Front Immunol"},{"key":"1736_CR14","doi-asserted-by":"crossref","unstructured":"McGonagle D, Sharif K, O'Regan A, Bridgewood C. The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease. Autoimmun Rev. 2020;19:102537.","DOI":"10.1016\/j.autrev.2020.102537"},{"key":"1736_CR15","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00296-020-04749-4","volume":"41","author":"J Kabeerdoss","year":"2021","unstructured":"Kabeerdoss J, Pilania RK, Karkhele R, Kumar TS, Danda D, Singh S. Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological mechanisms, clinical manifestations and management. Rheumatol Int. 2021;41:19\u201332.","journal-title":"Rheumatol Int"},{"key":"1736_CR16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.jdcr.2021.02.015","volume":"10","author":"K Mieczkowska","year":"2021","unstructured":"Mieczkowska K, Zhu TH, Hoffman L, Blasiak RC, Shulman KJ, Birnbaum M, et al. Two adult cases of multisystem inflammatory syndrome associated with SARS-CoV-2. JAAD Case Rep. 2021;10:113\u20135.","journal-title":"JAAD Case Rep"},{"key":"1736_CR17","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1016\/S0140-6736(20)31526-9","volume":"396","author":"S Shaigany","year":"2020","unstructured":"Shaigany S, Gnirke M, Guttmann A, Chong H, Meehan S, Raabe V, et al. An adult with Kawasaki-like multisystem inflammatory syndrome associated with COVID-19. Lancet. 2020;396:e8\u201310.","journal-title":"Lancet"},{"key":"1736_CR18","doi-asserted-by":"crossref","unstructured":"So NA, So J, Centkowski S, Rana J, Aleshin M, Kwong BY, et al. Histopathologic correlation of skin manifestations of multisystemic inflammatory syndrome in adults (MIS-A) associated with SARS-CoV-2 infection. JAAD Case Rep. 2021.","DOI":"10.1016\/j.jdcr.2021.06.031"},{"key":"1736_CR19","doi-asserted-by":"crossref","unstructured":"Chowdhary A, Joy E, Plein S, Abdel-Rahman SE. Multisystem inflammatory syndrome in an adult with SARS-CoV-2 infection. Eur Heart J Cardiovasc Imaging. 2021;22:e17.","DOI":"10.1093\/ehjci\/jeaa232"},{"key":"1736_CR20","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1186\/s12879-020-05439-z","volume":"20","author":"AD Kofman","year":"2020","unstructured":"Kofman AD, Sizemore EK, Detelich JF, Albrecht B, Piantadosi AL. A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report. BMC Infect Dis. 2020;20:716.","journal-title":"BMC Infect Dis"},{"key":"1736_CR21","first-page":"e13","volume":"73","author":"LA Henderson","year":"2021","unstructured":"Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, et al. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. Arthritis Rheumatol. 2021;73:e13\u201329.","journal-title":"Arthritis Rheumatol"}],"container-title":["Virology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-021-01736-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12985-021-01736-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-021-01736-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T13:20:21Z","timestamp":1641475221000},"score":1,"resource":{"primary":{"URL":"https:\/\/virologyj.biomedcentral.com\/articles\/10.1186\/s12985-021-01736-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,6]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["1736"],"URL":"https:\/\/doi.org\/10.1186\/s12985-021-01736-4","relation":{},"ISSN":["1743-422X"],"issn-type":[{"value":"1743-422X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,6]]},"assertion":[{"value":"12 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written patient consent statement was received.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Dr. Bayram and the other authors are employed by The Hamidiye Sisli Etfal Education and Research Hospital. Drs Bayram, Sevgi, Yavuz, Cancetin and Gurler report no conflicts of interest related to this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"9"}}