{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:48:37Z","timestamp":1791492517567,"version":"4.3.4"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:00:00Z","timestamp":1751068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:00:00Z","timestamp":1751068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virol J"],"DOI":"10.1186\/s12985-025-02833-4","type":"journal-article","created":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:21:06Z","timestamp":1751070066000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Human papillomavirus infection in males: implications for fertility, assisted reproductive outcomes, and vaccination strategies"],"prefix":"10.1186","volume":"22","author":[{"given":"Xian-hua","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-hua","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,28]]},"reference":[{"key":"2833_CR1","doi-asserted-by":"publisher","unstructured":"Lyu Z, et al. Human papillomavirus in semen and the risk for male infertility: a systematic review and meta-analysis. BMC Infect Dis. 2017;17. https:\/\/doi.org\/10.1186\/s12879-017-2812-z.","DOI":"10.1186\/s12879-017-2812-z"},{"key":"2833_CR2","doi-asserted-by":"publisher","unstructured":"Graham SV. The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review. Clinical science (London, England: 1979) 131, 2201\u20132221. https:\/\/doi.org\/10.1042\/cs20160786 (2017).","DOI":"10.1042\/cs20160786"},{"key":"2833_CR3","doi-asserted-by":"publisher","unstructured":"Gheit T. Mucosal and cutaneous human papillomavirus infections and Cancer biology. Front Oncol. 2019;9. https:\/\/doi.org\/10.3389\/fonc.2019.00355.","DOI":"10.3389\/fonc.2019.00355"},{"key":"2833_CR4","doi-asserted-by":"publisher","unstructured":"Sucato A, et al. Human papillomavirus and male infertility: what do we know?? Int J Mol Sci. 2023;24. https:\/\/doi.org\/10.3390\/ijms242417562.","DOI":"10.3390\/ijms242417562"},{"key":"2833_CR5","doi-asserted-by":"publisher","unstructured":"Chenafi-Adham S, Boussetta-Charfi O, Pillet S, Bourlet T. Impact of human papillomavirus (HPV) on male and female fertility. Pathogens (Basel Switzerland). 2024;13. https:\/\/doi.org\/10.3390\/pathogens13121076.","DOI":"10.3390\/pathogens13121076"},{"key":"2833_CR6","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1007\/s10815-014-0280-6","volume":"31","author":"E Tahmasbpour","year":"2014","unstructured":"Tahmasbpour E, Balasubramanian D, Agarwal A. A multi-faceted approach to Understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART). J Assist Reprod Genet. 2014;31:1115\u201337. https:\/\/doi.org\/10.1007\/s10815-014-0280-6.","journal-title":"J Assist Reprod Genet"},{"key":"2833_CR7","doi-asserted-by":"publisher","unstructured":"Diagnostic evaluation of the. infertile female: a committee opinion. Fertility and sterility 103, e44-50. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.03.019 (2015).","DOI":"10.1016\/j.fertnstert.2015.03.019"},{"key":"2833_CR8","doi-asserted-by":"publisher","unstructured":"Sucato A, et al. Human papillomavirus infection in partners of women attending cervical Cancer screening: A pilot study on prevalence, distribution, and potential use of vaccines. Vaccines. 2025;13. https:\/\/doi.org\/10.3390\/vaccines13020172.","DOI":"10.3390\/vaccines13020172"},{"key":"2833_CR9","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1086\/507432","volume":"194","author":"EF Dunne","year":"2006","unstructured":"Dunne EF, Nielson CM, Stone KM, Markowitz LE, Giuliano AR. Prevalence of HPV infection among men: A systematic review of the literature. J Infect Dis. 2006;194:1044\u201357. https:\/\/doi.org\/10.1086\/507432.","journal-title":"J Infect Dis"},{"key":"2833_CR10","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1016\/j.jadohealth.2011.03.010","volume":"48","author":"JS Smith","year":"2011","unstructured":"Smith JS, Gilbert PA, Melendy A, Rana RK, Pimenta JM. Age-specific prevalence of human papillomavirus infection in males: a global review. J Adolesc Health. 2011;48:540\u201352. https:\/\/doi.org\/10.1016\/j.jadohealth.2011.03.010.","journal-title":"J Adolesc Health"},{"key":"2833_CR11","doi-asserted-by":"publisher","unstructured":"Rodr\u00edguez-\u00c1lvarez MI, et al. Prevalence and risk factors of human papillomavirus in male patients: A systematic review and Meta-Analysis. Int J Environ Res Public Health. 2018;15. https:\/\/doi.org\/10.3390\/ijerph15102210.","DOI":"10.3390\/ijerph15102210"},{"key":"2833_CR12","doi-asserted-by":"publisher","first-page":"e1345","DOI":"10.1016\/s2214-109x(23)00305-4","volume":"11","author":"L Bruni","year":"2023","unstructured":"Bruni L, et al. Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis. Lancet Glob Health. 2023;11:e1345\u201362. https:\/\/doi.org\/10.1016\/s2214-109x(23)00305-4.","journal-title":"Lancet Glob Health"},{"key":"2833_CR13","doi-asserted-by":"publisher","first-page":"26343","DOI":"10.1038\/srep26343","volume":"6","author":"F Liu","year":"2016","unstructured":"Liu F, et al. Human papillomavirus DNA positivity and seropositivity in rural Chinese men and women: a population-based cross-sectional study. Sci Rep. 2016;6:26343. https:\/\/doi.org\/10.1038\/srep26343.","journal-title":"Sci Rep"},{"key":"2833_CR14","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s40618-023-02192-3","volume":"47","author":"A Garolla","year":"2024","unstructured":"Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A. HPV-related diseases in male patients: an underestimated conundrum. J Endocrinol Investig. 2024;47:261\u201374. https:\/\/doi.org\/10.1007\/s40618-023-02192-3.","journal-title":"J Endocrinol Investig"},{"key":"2833_CR15","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1093\/humrep\/des009","volume":"27","author":"A Garolla","year":"2012","unstructured":"Garolla A, et al. Human papillomavirus sperm infection and assisted reproduction: a dangerous hazard with a possible safe solution. Hum Reprod (Oxford England). 2012;27:967\u201373. https:\/\/doi.org\/10.1093\/humrep\/des009.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2833_CR16","doi-asserted-by":"publisher","first-page":"e15036","DOI":"10.1371\/journal.pone.0015036","volume":"6","author":"C Foresta","year":"2011","unstructured":"Foresta C, et al. Mechanism of human papillomavirus binding to human spermatozoa and fertilizing ability of infected spermatozoa. PLoS ONE. 2011;6:e15036. https:\/\/doi.org\/10.1371\/journal.pone.0015036.","journal-title":"PLoS ONE"},{"key":"2833_CR17","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.jiac.2018.04.011","volume":"24","author":"K Nakashima","year":"2018","unstructured":"Nakashima K, et al. Risk factors for human papillomavirus detection in urine samples of heterosexual men visiting urological clinics in Japan. J Infect Chemother. 2018;24:713\u20137. https:\/\/doi.org\/10.1016\/j.jiac.2018.04.011.","journal-title":"J Infect Chemother"},{"key":"2833_CR18","doi-asserted-by":"publisher","first-page":"306","DOI":"10.22074\/ijfs.2019.5421","volume":"12","author":"M Moghimi","year":"2019","unstructured":"Moghimi M, Zabihi-Mahmoodabadi S, Kheirkhah-Vakilabad A, Kargar Z. Significant correlation between High-Risk HPV DNA in semen and impairment of sperm quality in infertile men. Int J Fertility Steril. 2019;12:306\u20139. https:\/\/doi.org\/10.22074\/ijfs.2019.5421.","journal-title":"Int J Fertility Steril"},{"key":"2833_CR19","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1093\/humrep\/dey348","volume":"34","author":"L Boeri","year":"2019","unstructured":"Boeri L, et al. High-risk human papillomavirus in semen is associated with poor sperm progressive motility and a high sperm DNA fragmentation index in infertile men. Hum Reprod (Oxford England). 2019;34:209\u201317. https:\/\/doi.org\/10.1093\/humrep\/dey348.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2833_CR20","doi-asserted-by":"publisher","first-page":"9714","DOI":"10.26355\/eurrev_201911_19533","volume":"23","author":"DM Ma","year":"2019","unstructured":"Ma DM, et al. Distribution of high-risk human papillomavirus genotypes in male attendees at a clinic for sexually transmitted infections in Northern China. Eur Rev Med Pharmacol Sci. 2019;23:9714\u201320. https:\/\/doi.org\/10.26355\/eurrev_201911_19533.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2833_CR21","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1016\/j.fertnstert.2020.01.010","volume":"113","author":"M Weinberg","year":"2020","unstructured":"Weinberg M, Sar-Shalom Nahshon C, Feferkorn I, Bornstein J. Evaluation of human papilloma virus in semen as a risk factor for low sperm quality and poor in vitro fertilization outcomes: a systematic review and meta-analysis. Fertil Steril. 2020;113:955\u2013e969954. https:\/\/doi.org\/10.1016\/j.fertnstert.2020.01.010.","journal-title":"Fertil Steril"},{"key":"2833_CR22","doi-asserted-by":"publisher","first-page":"493","DOI":"10.4103\/aja.aja_77_17","volume":"20","author":"YQ Xiong","year":"2018","unstructured":"Xiong YQ, Chen YX, Cheng MJ, He WQ, Chen Q. The risk of human papillomavirus infection for male fertility abnormality: a meta-analysis. Asian J Androl. 2018;20:493\u20137. https:\/\/doi.org\/10.4103\/aja.aja_77_17.","journal-title":"Asian J Androl"},{"key":"2833_CR23","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1093\/humrep\/dev317","volume":"31","author":"R Luttmer","year":"2016","unstructured":"Luttmer R, et al. Presence of human papillomavirus in semen in relation to semen quality. Hum Reprod (Oxford England). 2016;31:280\u20136. https:\/\/doi.org\/10.1093\/humrep\/dev317.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2833_CR24","doi-asserted-by":"publisher","first-page":"27422","DOI":"10.1038\/s41598-024-79047-1","volume":"14","author":"T Notari","year":"2024","unstructured":"Notari T, et al. Human papillomavirus and male infertility correlation analysis following world health organization 2021 guidelines. Sci Rep. 2024;14:27422. https:\/\/doi.org\/10.1038\/s41598-024-79047-1.","journal-title":"Sci Rep"},{"key":"2833_CR25","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1086\/521629","volume":"196","author":"AR Giuliano","year":"2007","unstructured":"Giuliano AR, et al. The optimal anatomic sites for sampling heterosexual men for human papillomavirus (HPV) detection: the HPV detection in men study. J Infect Dis. 2007;196:1146\u201352. https:\/\/doi.org\/10.1086\/521629.","journal-title":"J Infect Dis"},{"key":"2833_CR26","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1093\/humrep\/det453","volume":"29","author":"C Laprise","year":"2014","unstructured":"Laprise C, Trottier H, Monnier P, Coutl\u00e9e F, Mayrand MH. Prevalence of human papillomaviruses in semen: a systematic review and meta-analysis. Hum Reprod (Oxford England). 2014;29:640\u201351. https:\/\/doi.org\/10.1093\/humrep\/det453.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2833_CR27","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1111\/andr.284","volume":"3","author":"C Foresta","year":"2015","unstructured":"Foresta C, Noventa M, De Toni L, Gizzo S, Garolla A. HPV-DNA sperm infection and infertility: from a systematic literature review to a possible clinical management proposal. Andrology. 2015;3:163\u201373. https:\/\/doi.org\/10.1111\/andr.284.","journal-title":"Andrology"},{"key":"2833_CR28","doi-asserted-by":"publisher","unstructured":"Depuydt C, et al. Negative impact of elevated DNA fragmentation and human papillomavirus (HPV) presence in sperm on the outcome of Intra-Uterine insemination (IUI). J Clin Med. 2021;10. https:\/\/doi.org\/10.3390\/jcm10040717.","DOI":"10.3390\/jcm10040717"},{"key":"2833_CR29","doi-asserted-by":"publisher","unstructured":"Isaguliants M, et al. Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection. Infect Agents cancer. 2021;16. https:\/\/doi.org\/10.1186\/s13027-021-00368-1.","DOI":"10.1186\/s13027-021-00368-1"},{"key":"2833_CR30","doi-asserted-by":"publisher","unstructured":"Capra G, et al. Human papillomavirus (HPV) infection and its impact on male infertility. Life (Basel Switzerland). 2022;12. https:\/\/doi.org\/10.3390\/life12111919.","DOI":"10.3390\/life12111919"},{"key":"2833_CR31","doi-asserted-by":"publisher","unstructured":"Noventa M, Andrisani A, Gizzo S, Nardelli GB, Ambrosini G. Is it time to shift the attention on early stages embryo development to avoid inconclusive evidence on HPV-related infertility: debate and proposal. Reproductive Biology Endocrinology: RB&E. 2014;12(48). https:\/\/doi.org\/10.1186\/1477-7827-12-48.","DOI":"10.1186\/1477-7827-12-48"},{"key":"2833_CR32","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1093\/humrep\/dem404","volume":"23","author":"LM Gomez","year":"2008","unstructured":"Gomez LM, et al. Placental infection with human papillomavirus is associated with spontaneous preterm delivery. Hum Reprod (Oxford England). 2008;23:709\u201315. https:\/\/doi.org\/10.1093\/humrep\/dem404.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2833_CR33","doi-asserted-by":"publisher","unstructured":"Condrat CE, Filip L, Gherghe M, Cretoiu D, Suciu N. Maternal HPV infection: effects on pregnancy outcome. Viruses. 2021;13. https:\/\/doi.org\/10.3390\/v13122455.","DOI":"10.3390\/v13122455"},{"key":"2833_CR34","doi-asserted-by":"publisher","unstructured":"Popescu SD, et al. Maternal HPV infection and the estimated risks for adverse pregnancy Outcomes-A systematic review. Diagnostics (Basel Switzerland). 2022;12. https:\/\/doi.org\/10.3390\/diagnostics12061471.","DOI":"10.3390\/diagnostics12061471"},{"key":"2833_CR35","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.fertnstert.2015.09.018","volume":"105","author":"A Garolla","year":"2016","unstructured":"Garolla A, et al. Spontaneous fertility and in vitro fertilization outcome: new evidence of human papillomavirus sperm infection. Fertil Steril. 2016;105:65\u2013e7261. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.09.018.","journal-title":"Fertil Steril"},{"key":"2833_CR36","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1016\/j.fertnstert.2019.02.002","volume":"111","author":"CE Depuydt","year":"2019","unstructured":"Depuydt CE, et al. Infectious human papillomavirus virions in semen reduce clinical pregnancy rates in women undergoing intrauterine insemination. Fertil Steril. 2019;111:1135\u201344. https:\/\/doi.org\/10.1016\/j.fertnstert.2019.02.002.","journal-title":"Fertil Steril"},{"key":"2833_CR37","doi-asserted-by":"publisher","first-page":"12","DOI":"10.5152\/tud.2018.96393","volume":"45","author":"S Tangal","year":"2019","unstructured":"Tangal S, et al. DNA fragmentation index and human papilloma virus in males with previous assisted reproductive technology failures. Turkish J Urol. 2019;45:12\u20136. https:\/\/doi.org\/10.5152\/tud.2018.96393.","journal-title":"Turkish J Urol"},{"key":"2833_CR38","doi-asserted-by":"publisher","first-page":"336","DOI":"10.5173\/ceju.2023.74","volume":"76","author":"K Gkeka","year":"2023","unstructured":"Gkeka K, et al. Recurrent miscarriage and male factor infertility: diagnostic and therapeutic implications. A narrative review. Cent Eur J Urol. 2023;76:336\u201346. https:\/\/doi.org\/10.5173\/ceju.2023.74.","journal-title":"Cent Eur J Urol"},{"key":"2833_CR39","doi-asserted-by":"publisher","first-page":"e28697","DOI":"10.1002\/jmv.28697","volume":"95","author":"S Das","year":"2023","unstructured":"Das S, et al. The impact of human papilloma virus on human reproductive health and the effect on male infertility: an updated review. J Med Virol. 2023;95:e28697. https:\/\/doi.org\/10.1002\/jmv.28697.","journal-title":"J Med Virol"},{"key":"2833_CR40","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1136\/sextrans-2018-053751","volume":"95","author":"M Checchi","year":"2019","unstructured":"Checchi M, Mesher D, Mohammed H, Soldan K. Declines in anogenital warts diagnoses since the change in 2012 to use the quadrivalent HPV vaccine in england: data to end 2017. Sex Transm Infect. 2019;95:368\u201373. https:\/\/doi.org\/10.1136\/sextrans-2018-053751.","journal-title":"Sex Transm Infect"},{"key":"2833_CR41","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1016\/s1473-3099(21)00071-2","volume":"21","author":"EPF Chow","year":"2021","unstructured":"Chow EPF, et al. Effect on genital warts in Australian female and heterosexual male individuals after introduction of the National human papillomavirus gender-neutral vaccination programme: an analysis of National Sentinel surveillance data from 2004-18. Lancet Infect Dis. 2021;21:1747\u201356. https:\/\/doi.org\/10.1016\/s1473-3099(21)00071-2.","journal-title":"Lancet Infect Dis"},{"key":"2833_CR42","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1016\/s1473-3099(20)30687-3","volume":"21","author":"EPF Chow","year":"2021","unstructured":"Chow EPF, et al. Prevalence of human papillomavirus in young men who have sex with men after the implementation of gender-neutral HPV vaccination: a repeated cross-sectional study. Lancet Infect Dis. 2021;21:1448\u201357. https:\/\/doi.org\/10.1016\/s1473-3099(20)30687-3.","journal-title":"Lancet Infect Dis"},{"key":"2833_CR43","doi-asserted-by":"publisher","first-page":"100251","DOI":"10.1016\/j.lanwpc.2021.100251","volume":"16","author":"L Khawar","year":"2021","unstructured":"Khawar L, et al. Genital warts trends in Australian and overseas-born people in australia: A cross-sectional trend analysis to measure progress towards control and elimination. Lancet Reg Health Western Pac. 2021;16:100251. https:\/\/doi.org\/10.1016\/j.lanwpc.2021.100251.","journal-title":"Lancet Reg Health Western Pac"},{"key":"2833_CR44","doi-asserted-by":"publisher","first-page":"6907","DOI":"10.1016\/j.vaccine.2019.09.052","volume":"37","author":"EPF Chow","year":"2019","unstructured":"Chow EPF, et al. Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in australia: 2014\u20132017. Vaccine. 2019;37:6907\u201314. https:\/\/doi.org\/10.1016\/j.vaccine.2019.09.052.","journal-title":"Vaccine"},{"key":"2833_CR45","doi-asserted-by":"publisher","first-page":"101585","DOI":"10.1016\/j.eclinm.2022.101585","volume":"52","author":"L Staadegaard","year":"2022","unstructured":"Staadegaard L, et al. Immunogenicity, safety, and efficacy of the HPV vaccines among people living with HIV: A systematic review and meta-analysis. EClinicalMedicine. 2022;52:101585. https:\/\/doi.org\/10.1016\/j.eclinm.2022.101585.","journal-title":"EClinicalMedicine"},{"key":"2833_CR46","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1093\/infdis\/jiaa302","volume":"222","author":"R Balaji","year":"2020","unstructured":"Balaji R, MacCosham A, Williams K, El-Zein M, Franco EL. Directionality of genital human papillomavirus infection transmission within heterosexual couples: A systematic review and Meta-analysis. J Infect Dis. 2020;222:1928\u201337. https:\/\/doi.org\/10.1093\/infdis\/jiaa302.","journal-title":"J Infect Dis"},{"key":"2833_CR47","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1097\/olq.0000000000001620","volume":"49","author":"A MacCosham","year":"2022","unstructured":"MacCosham A, et al. Protection to self and to one\u2019s sexual partner after human papillomavirus vaccination: preliminary analysis from the transmission reduction and prevention with HPV vaccination study. Sex Transm Dis. 2022;49:414\u201322. https:\/\/doi.org\/10.1097\/olq.0000000000001620.","journal-title":"Sex Transm Dis"},{"key":"2833_CR48","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/s0140-6736(19)30298-3","volume":"394","author":"M Drolet","year":"2019","unstructured":"Drolet M, B\u00e9nard \u00c9, P\u00e9rez N, Brisson M. Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis. Lancet (London England). 2019;394:497\u2013509. https:\/\/doi.org\/10.1016\/s0140-6736(19)30298-3.","journal-title":"Lancet (London England)"},{"key":"2833_CR49","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1056\/NEJMoa1010971","volume":"365","author":"JM Palefsky","year":"2011","unstructured":"Palefsky JM, et al. HPV vaccine against anal HPV infection and anal intraepithelial neoplasia. N Engl J Med. 2011;365:1576\u201385. https:\/\/doi.org\/10.1056\/NEJMoa1010971.","journal-title":"N Engl J Med"},{"key":"2833_CR50","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1038\/s41598-018-19369-z","volume":"8","author":"A Garolla","year":"2018","unstructured":"Garolla A, et al. Human papillomavirus prophylactic vaccination improves reproductive outcome in infertile patients with HPV semen infection: a retrospective study. Sci Rep. 2018;8:912. https:\/\/doi.org\/10.1038\/s41598-018-19369-z.","journal-title":"Sci Rep"},{"key":"2833_CR51","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1016\/j.ebiom.2015.09.005","volume":"2","author":"C Foresta","year":"2015","unstructured":"Foresta C, et al. HPV prophylactic vaccination in males improves the clearance of semen infection. EBioMedicine. 2015;2:1487\u201393. https:\/\/doi.org\/10.1016\/j.ebiom.2015.09.005.","journal-title":"EBioMedicine"},{"key":"2833_CR52","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.fertnstert.2012.09.006","volume":"99","author":"A Garolla","year":"2013","unstructured":"Garolla A, et al. Association, prevalence, and clearance of human papillomavirus and antisperm antibodies in infected semen samples from infertile patients. Fertil Steril. 2013;99:125\u2013e131122. https:\/\/doi.org\/10.1016\/j.fertnstert.2012.09.006.","journal-title":"Fertil Steril"},{"key":"2833_CR53","doi-asserted-by":"publisher","first-page":"643539","DOI":"10.3389\/fendo.2021.643539","volume":"12","author":"F Muscianisi","year":"2021","unstructured":"Muscianisi F, et al. Is HPV the novel target in male idiopathic infertility?? A systematic review of the literature. Front Endocrinol. 2021;12:643539. https:\/\/doi.org\/10.3389\/fendo.2021.643539.","journal-title":"Front Endocrinol"},{"key":"2833_CR54","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/j.1365-2605.2010.01075.x","volume":"34","author":"C Foresta","year":"2011","unstructured":"Foresta C, et al. Human papilloma virus in the sperm cryobank: an emerging problem? Int J Androl. 2011;34:242\u20136. https:\/\/doi.org\/10.1111\/j.1365-2605.2010.01075.x.","journal-title":"Int J Androl"},{"key":"2833_CR55","doi-asserted-by":"publisher","first-page":"e70048","DOI":"10.1002\/hsr2.70048","volume":"7","author":"A Garolla","year":"2024","unstructured":"Garolla A, et al. Papillomavirus infection and male infertility: A systematic review and meta-analysis. Health Sci Rep. 2024;7:e70048. https:\/\/doi.org\/10.1002\/hsr2.70048.","journal-title":"Health Sci Rep"},{"key":"2833_CR56","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1080\/13685538.2021.2023126","volume":"25","author":"R Cannarella","year":"2022","unstructured":"Cannarella R, et al. Impact of seminal low-risk human papillomavirus infection on sperm parameters of adult men. Aging Male: Official J Int Soc Study Aging Male. 2022;25:17\u201322. https:\/\/doi.org\/10.1080\/13685538.2021.2023126.","journal-title":"Aging Male: Official J Int Soc Study Aging Male"},{"key":"2833_CR57","doi-asserted-by":"publisher","unstructured":"Zacharis K, et al. Human papilloma virus (HPV) and fertilization: A Mini review. Med (Kaunas Lithuania). 2018;54. https:\/\/doi.org\/10.3390\/medicina54040050.","DOI":"10.3390\/medicina54040050"},{"key":"2833_CR58","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1093\/infdis\/jit191","volume":"208","author":"CM Pierce Campbell","year":"2013","unstructured":"Pierce Campbell CM, et al. Consistent condom use reduces the genital human papillomavirus burden among high-risk men: the HPV infection in men study. J Infect Dis. 2013;208:373\u201384. https:\/\/doi.org\/10.1093\/infdis\/jit191.","journal-title":"J Infect Dis"},{"key":"2833_CR59","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1002\/ijc.33716","volume":"149","author":"C van Schalkwyk","year":"2021","unstructured":"van Schalkwyk C, Moodley J, Welte A, Johnson LF. Modelling the impact of prevention strategies on cervical cancer incidence in South Africa. Int J Cancer. 2021;149:1564\u201375. https:\/\/doi.org\/10.1002\/ijc.33716.","journal-title":"Int J Cancer"},{"key":"2833_CR60","doi-asserted-by":"publisher","first-page":"591837","DOI":"10.3389\/fendo.2020.591837","volume":"11","author":"A Garolla","year":"2020","unstructured":"Garolla A, et al. Practical clinical and diagnostic pathway for the investigation of the infertile couple. Front Endocrinol. 2020;11:591837. https:\/\/doi.org\/10.3389\/fendo.2020.591837.","journal-title":"Front Endocrinol"}],"container-title":["Virology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-025-02833-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12985-025-02833-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12985-025-02833-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:21:07Z","timestamp":1751070067000},"score":1,"resource":{"primary":{"URL":"https:\/\/virologyj.biomedcentral.com\/articles\/10.1186\/s12985-025-02833-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,28]]},"references-count":60,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["2833"],"URL":"https:\/\/doi.org\/10.1186\/s12985-025-02833-4","relation":{},"ISSN":["1743-422X"],"issn-type":[{"value":"1743-422X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,28]]},"assertion":[{"value":"15 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All authors have read the manuscript and agreed to submit it to Reproductive Sciences.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"209"}}