{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T01:29:29Z","timestamp":1790040569912,"version":"4.0.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88881.708719\/2022-01"],"award-info":[{"award-number":["88881.708719\/2022-01"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.708718\/2022-00"],"award-info":[{"award-number":["88887.708718\/2022-00"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.466981\/2019-00"],"award-info":[{"award-number":["88887.466981\/2019-00"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["E-26\/211.104\/2021"],"award-info":[{"award-number":["E-26\/211.104\/2021"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chiropr Man Therap"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Clinical practice guidelines recommend spinal manipulation for patients with low back pain. However, the effects of spinal manipulation have contradictory findings compared to placebo intervention. Therefore, this study investigated the immediate effects of lumbar spinal manipulation on pressure pain threshold (PPT) and postural stability in people with chronic low back pain (cLBP). Second, we investigated the immediate effect of lumbar spinal manipulation on pain intensity and the interference of the participant beliefs about which treatment was received in the PPT, postural stability, and pain intensity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A two-arm, randomised, placebo-controlled, double-blind trial was performed. Eighty participants with nonspecific cLPB and a minimum score of 3 on the Numeric Pain Rating Scale received one session of lumbar spinal manipulation (<jats:italic>n<\/jats:italic>\u2009=\u200940) or simulated lumbar spinal manipulation (<jats:italic>n<\/jats:italic>\u2009=\u200940). Primary outcomes were local and remote PPTs and postural stability. Secondary outcomes were pain intensity and participant\u2019s perceived treatment allocation. Between-group mean differences and their 95% confidence intervals (CIs) estimated the treatment effect. One-way analysis of covariance (ANCOVA) was performed to assess whether beliefs about which treatment was received influenced the outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Participants had a mean (SD) age of 34.9 (10.5) years, and 50 (62.5%) were women. Right L5 [between-group mean difference\u2009=\u20090.55 (95%CI 0.19 to 0.90)], left L5 [between-group mean difference\u2009=\u20090.45 (95%CI 0.13 to 0.76)], right L1 [between-group mean difference\u2009=\u20090.41 (95%CI 0.05 to 0.78)], left L1 [between-group mean difference\u2009=\u20090.57 (95%CI 0.15 to 0.99)], left DT [between-group mean difference\u2009=\u20090.35 (95%CI 0.04 to 0.65)], and right LE [between-group mean difference\u2009=\u20090.34 (95%CI 0.08 to 0.60)] showed superior treatment effect in the spinal manipulation group than sham. Neither intervention altered postural stability. Self-reported pain intensity showed clinically significant decreases in both groups after the intervention. A higher proportion of participants in the spinal manipulation group achieved more than two points of pain relief (spinal manipulation\u2009=\u200990%; sham\u2009=\u200960%). The participants\u2019 perceived treatment allocation did not affect the outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>One spinal manipulation session reduces lumbar pain sensitivity but does not affect postural stability compared to a sham session in individuals with cLPB. Self-reported pain intensity lowered in both groups and a higher proportion of participants in the spinal manipulation group reached clinically significant pain relief. The participant\u2019s belief in receiving the manipulation did not appear to have influenced the outcomes since the adjusted model revealed similar findings.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12998-024-00541-4","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T16:02:08Z","timestamp":1717171328000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["One spinal manipulation session reduces local pain sensitivity but does not affect postural stability in individuals with chronic low back pain: a randomised, placebo-controlled trial"],"prefix":"10.1186","volume":"32","author":[{"given":"Jo\u00e3o Paulo","family":"Freitas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia Amaral","family":"Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9522-8523","authenticated-orcid":false,"given":"Juliana Valentim","family":"Bittencourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine Marcondes","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ney","family":"Meziat-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0177-9816","authenticated-orcid":false,"given":"Leandro Alberto Calazans","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,31]]},"reference":[{"issue":"10159","key":"541_CR1","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","volume":"392","author":"Collaborators GBDIIaP","year":"2018","unstructured":"Collaborators GBDIIaP. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990\u20132017: a systematic analysis for the global burden of Disease Study 2017. Lancet. 2018;392(10159):1789\u2013858. https:\/\/doi.org\/10.1016\/S0140-6736(18)32279-7","journal-title":"Lancet"},{"issue":"10137","key":"541_CR2","doi-asserted-by":"publisher","first-page":"2356","DOI":"10.1016\/S0140-6736(18)30480-X","volume":"391","author":"J Hartvigsen","year":"2018","unstructured":"Hartvigsen J, Hancock MJ, Kongsted A, Louw Q, Ferreira ML, Genevay S, et al. What low back pain is and why we need to pay attention. Lancet. 2018;391(10137):2356\u201367. https:\/\/doi.org\/10.1016\/S0140-6736(18)30480-X","journal-title":"Lancet"},{"issue":"3","key":"541_CR3","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.jphys.2019.04.010","volume":"65","author":"T da Silva","year":"2019","unstructured":"da Silva T, Mills K, Brown BT, Pocovi N, de Campos T, Maher C, et al. Recurrence of low back pain is common: a prospective inception cohort study. J Physiother. 2019;65(3):159\u201365. https:\/\/doi.org\/10.1016\/j.jphys.2019.04.010","journal-title":"J Physiother"},{"issue":"18","key":"541_CR4","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1056\/NEJMcp2032396","volume":"386","author":"A Chiarotto","year":"2022","unstructured":"Chiarotto A, Koes BW. Nonspecific low back Pain. N Engl J Med. 2022;386(18):1732\u201340. https:\/\/doi.org\/10.1056\/NEJMcp2032396","journal-title":"N Engl J Med"},{"issue":"7","key":"541_CR5","doi-asserted-by":"publisher","first-page":"514","DOI":"10.7326\/M16-2367","volume":"166","author":"A Qaseem","year":"2017","unstructured":"Qaseem A, Wilt TJ, McLean RM, Forciea MA, Clinical Guidelines Committee of the American College of P, Denberg TD, et al. Noninvasive treatments for Acute, Subacute, and chronic low back Pain: a clinical practice Guideline from the American College of Physicians. Ann Intern Med. 2017;166(7):514\u201330. https:\/\/doi.org\/10.7326\/M16-2367","journal-title":"Ann Intern Med"},{"key":"541_CR6","unstructured":"Guidelines NIfHaCE. Low Back Pain and Sciatica in Over 16s: Assessment and Management. London 2016."},{"issue":"8","key":"541_CR7","doi-asserted-by":"publisher","first-page":"E505","DOI":"10.1097\/BRS.0000000000003814","volume":"46","author":"A de Zoete","year":"2021","unstructured":"de Zoete A, de Boer MR, Rubinstein SM, van Tulder MW, Underwood M, Hayden JA, et al. Moderators of the effect of spinal manipulative therapy on Pain relief and function in patients with chronic low back Pain: an individual Participant Data Meta-analysis. Spine (Phila Pa 1976). 2021;46(8):E505\u201317. https:\/\/doi.org\/10.1097\/BRS.0000000000003814","journal-title":"Spine (Phila Pa 1976)"},{"key":"541_CR8","doi-asserted-by":"publisher","first-page":"l689","DOI":"10.1136\/bmj.l689","volume":"364","author":"SM Rubinstein","year":"2019","unstructured":"Rubinstein SM, de Zoete A, van Middelkoop M, Assendelft WJJ, de Boer MR, van Tulder MW. Benefits and harms of spinal manipulative therapy for the treatment of chronic low back pain: systematic review and meta-analysis of randomised controlled trials. BMJ. 2019;364:l689. https:\/\/doi.org\/10.1136\/bmj.l689","journal-title":"BMJ"},{"key":"541_CR9","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.physio.2021.03.006","volume":"112","author":"A de Zoete","year":"2021","unstructured":"de Zoete A, Rubinstein SM, de Boer MR, Ostelo R, Underwood M, Hayden JA, et al. The effect of spinal manipulative therapy on pain relief and function in patients with chronic low back pain: an individual participant data meta-analysis. Physiotherapy. 2021;112:121\u201334. https:\/\/doi.org\/10.1016\/j.physio.2021.03.006","journal-title":"Physiotherapy"},{"issue":"7","key":"541_CR10","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1002\/ejp.1773","volume":"25","author":"C Gevers-Montoro","year":"2021","unstructured":"Gevers-Montoro C, Provencher B, Descarreaux M, Ortega de Mues A, Piche M. Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain. Eur J Pain. 2021;25(7):1429\u201348. https:\/\/doi.org\/10.1002\/ejp.1773","journal-title":"Eur J Pain"},{"issue":"5","key":"541_CR11","doi-asserted-by":"publisher","first-page":"e045106","DOI":"10.1136\/bmjopen-2020-045106","volume":"11","author":"C Lavazza","year":"2021","unstructured":"Lavazza C, Galli M, Abenavoli A, Maggiani A. Sham treatment effects in manual therapy trials on back pain patients: a systematic review and pairwise meta-analysis. BMJ Open. 2021;11(5):e045106. https:\/\/doi.org\/10.1136\/bmjopen-2020-045106","journal-title":"BMJ Open"},{"issue":"11","key":"541_CR12","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1136\/medethics-2012-101045","volume":"39","author":"RL Brim","year":"2013","unstructured":"Brim RL, Miller FG. The potential benefit of the placebo effect in sham-controlled trials: implications for risk-benefit assessments and informed consent. J Med Ethics. 2013;39(11):703\u20137. https:\/\/doi.org\/10.1136\/medethics-2012-101045","journal-title":"J Med Ethics"},{"issue":"3","key":"541_CR13","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1002\/mus.25635","volume":"56","author":"A Shaibani","year":"2017","unstructured":"Shaibani A, Frisaldi E, Benedetti F. Placebo response in pain, fatigue, and performance: possible implications for neuromuscular disorders. Muscle Nerve. 2017;56(3):358\u201367. https:\/\/doi.org\/10.1002\/mus.25635","journal-title":"Muscle Nerve"},{"key":"541_CR14","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s12998-018-0181-3","volume":"26","author":"M Honore","year":"2018","unstructured":"Honore M, Leboeuf-Yde C, Gagey O. The regional effect of spinal manipulation on the pressure pain threshold in asymptomatic subjects: a systematic literature review. Chiropr Man Th. 2018;26:11. https:\/\/doi.org\/10.1186\/s12998-018-0181-3","journal-title":"Chiropr Man Th"},{"issue":"1","key":"541_CR15","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12891-020-03873-3","volume":"22","author":"CG Nim","year":"2021","unstructured":"Nim CG, Kawchuk GN, Schiottz-Christensen B, O\u2019Neill S. Changes in pain sensitivity and spinal stiffness in relation to responder status following spinal manipulative therapy in chronic low Back pain: a secondary explorative analysis of a randomized trial. BMC Musculoskelet Disord. 2021;22(1):23. https:\/\/doi.org\/10.1186\/s12891-020-03873-3","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"541_CR16","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s12998-020-00316-7","volume":"28","author":"J Fagundes Loss","year":"2020","unstructured":"Fagundes Loss J, de Souza da Silva L, Ferreira Miranda I, Groisman S, Santiago Wagner Neto E, Souza C, et al. Immediate effects of a lumbar spine manipulation on pain sensitivity and postural control in individuals with nonspecific low back pain: a randomized controlled trial. Chiropr Man Th. 2020;28(1):25. https:\/\/doi.org\/10.1186\/s12998-020-00316-7","journal-title":"Chiropr Man Th"},{"key":"541_CR17","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.msksp.2019.05.011","volume":"43","author":"SL Aspinall","year":"2019","unstructured":"Aspinall SL, Jacques A, Leboeuf-Yde C, Etherington SJ, Walker BF. No difference in pressure pain threshold and temporal summation after lumbar spinal manipulation compared to sham: a randomised controlled trial in adults with low back pain. Musculoskelet Sci Pract. 2019;43:18\u201325. https:\/\/doi.org\/10.1016\/j.msksp.2019.05.011","journal-title":"Musculoskelet Sci Pract"},{"issue":"1","key":"541_CR18","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/s12998-020-00326-5","volume":"28","author":"SL Aspinall","year":"2020","unstructured":"Aspinall SL, Jacques A, Leboeuf-Yde C, Etherington SJ, Walker BF. Pressure pain threshold and temporal summation in adults with episodic and persistent low back pain trajectories: a secondary analysis at baseline and after lumbar manipulation or sham. Chiropr Man Th. 2020;28(1):36. https:\/\/doi.org\/10.1186\/s12998-020-00326-5","journal-title":"Chiropr Man Th"},{"issue":"5","key":"541_CR19","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.3233\/BMR-169588","volume":"30","author":"ES Soliman","year":"2017","unstructured":"Soliman ES, Shousha TM, Alayat MS. The effect of pain severity on postural stability and dynamic limits of stability in chronic low back pain. J Back Musculoskelet Rehabil. 2017;30(5):1023\u20139. https:\/\/doi.org\/10.3233\/BMR-169588","journal-title":"J Back Musculoskelet Rehabil"},{"issue":"4","key":"541_CR20","doi-asserted-by":"publisher","first-page":"887","DOI":"10.3233\/BMR-160721","volume":"29","author":"C Tsigkanos","year":"2016","unstructured":"Tsigkanos C, Gaskell L, Smirniotou A, Tsigkanos G. Static and dynamic balance deficiencies in chronic low back pain. J Back Musculoskelet Rehabil. 2016;29(4):887\u201393. https:\/\/doi.org\/10.3233\/BMR-160721","journal-title":"J Back Musculoskelet Rehabil"},{"issue":"13","key":"541_CR21","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1080\/09638288.2018.1433240","volume":"41","author":"Y Berenshteyn","year":"2019","unstructured":"Berenshteyn Y, Gibson K, Hackett GC, Trem AB, Wilhelm M. Is standing balance altered in individuals with chronic low back pain? A systematic review. Disabil Rehabil. 2019;41(13):1514\u201323. https:\/\/doi.org\/10.1080\/09638288.2018.1433240","journal-title":"Disabil Rehabil"},{"issue":"11","key":"541_CR22","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1080\/09638288.2017.1294627","volume":"40","author":"RA da Silva","year":"2018","unstructured":"da Silva RA, Vieira ER, Fernandes KBP, Andraus RA, Oliveira MR, Sturion LA, et al. People with chronic low back pain have poorer balance than controls in challenging tasks. Disabil Rehabil. 2018;40(11):1294\u2013300. https:\/\/doi.org\/10.1080\/09638288.2017.1294627","journal-title":"Disabil Rehabil"},{"issue":"1","key":"541_CR23","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s12891-018-1943-8","volume":"19","author":"G Rossettini","year":"2018","unstructured":"Rossettini G, Carlino E, Testa M. Clinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeletal pain. BMC Musculoskelet Disord. 2018;19(1):27. https:\/\/doi.org\/10.1186\/s12891-018-1943-8","journal-title":"BMC Musculoskelet Disord"},{"issue":"7","key":"541_CR24","doi-asserted-by":"publisher","first-page":"e2223903","DOI":"10.1001\/jamanetworkopen.2022.23903","volume":"5","author":"T Karjalainen","year":"2022","unstructured":"Karjalainen T, Heikkinen J, Busija L, Jokihaara J, Lewin AM, Naylor JM, et al. Use of Placebo and Nonoperative Control Groups in Surgical trials: a systematic review and Meta-analysis. JAMA Netw Open. 2022;5(7):e2223903. https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.23903","journal-title":"JAMA Netw Open"},{"issue":"11","key":"541_CR25","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1136\/annrheumdis-2015-208387","volume":"75","author":"K Zou","year":"2016","unstructured":"Zou K, Wong J, Abdullah N, Chen X, Smith T, Doherty M, et al. Examination of overall treatment effect and the proportion attributable to contextual effect in osteoarthritis: meta-analysis of randomised controlled trials. Ann Rheum Dis. 2016;75(11):1964\u201370. https:\/\/doi.org\/10.1136\/annrheumdis-2015-208387","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"541_CR26","doi-asserted-by":"publisher","first-page":"2792","DOI":"10.1097\/j.pain.0000000000002272","volume":"162","author":"RHW Strijkers","year":"2021","unstructured":"Strijkers RHW, Schreijenberg M, Gerger H, Koes BW, Chiarotto A. Effectiveness of placebo interventions for patients with nonspecific low back pain: a systematic review and meta-analysis. Pain. 2021;162(12):2792\u2013804. https:\/\/doi.org\/10.1097\/j.pain.0000000000002272","journal-title":"Pain"},{"issue":"11","key":"541_CR27","doi-asserted-by":"publisher","first-page":"e13680","DOI":"10.1111\/ijcp.13680","volume":"74","author":"WJ Mohamed Mohamed","year":"2020","unstructured":"Mohamed Mohamed WJ, Joseph L, Canby G, Paungmali A, Sitilertpisan P, Pirunsan U. Are patient expectations associated with treatment outcomes in individuals with chronic low back pain? A systematic review of randomised controlled trials. Int J Clin Pract. 2020;74(11):e13680. https:\/\/doi.org\/10.1111\/ijcp.13680","journal-title":"Int J Clin Pract"},{"issue":"8","key":"541_CR28","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.jclinepi.2010.03.004","volume":"63","author":"D Moher","year":"2010","unstructured":"Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ, et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol. 2010;63(8):e1\u201337. https:\/\/doi.org\/10.1016\/j.jclinepi.2010.03.004","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"541_CR29","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1186\/s13063-022-06111-4","volume":"23","author":"JP Freitas","year":"2022","unstructured":"Freitas JP, Correa LA, Bittencourt JV, Armstrong KM, Nogueira LAC. Immediate effects of spinal manipulation on painful sensitivity and postural stability in patients with chronic nonspecific low back pain: study protocol for a controlled randomised clinical trial. Trials. 2022;23(1):188. https:\/\/doi.org\/10.1186\/s13063-022-06111-4","journal-title":"Trials"},{"issue":"1","key":"541_CR30","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.bjane.2021.06.013","volume":"72","author":"J Rio","year":"2022","unstructured":"Rio J, Bittencourt JV, Correa LA, Freynhagen R, Reis F, Melo TB, et al. Cross-cultural adaptation of the painDETECT questionnaire into Brazilian Portuguese. Braz J Anesthesiol. 2022;72(1):44\u20138. https:\/\/doi.org\/10.1016\/j.bjane.2021.06.013","journal-title":"Braz J Anesthesiol"},{"key":"541_CR31","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12998-016-0128-5","volume":"24","author":"SL Dorron","year":"2016","unstructured":"Dorron SL, Losco BE, Drummond PD, Walker BF. Effect of lumbar spinal manipulation on local and remote pressure pain threshold and pinprick sensitivity in asymptomatic individuals: a randomised trial. Chiropr Man Th. 2016;24:47. https:\/\/doi.org\/10.1186\/s12998-016-0128-5","journal-title":"Chiropr Man Th"},{"key":"541_CR32","doi-asserted-by":"publisher","first-page":"11774","DOI":"10.1038\/srep11774","volume":"5","author":"A Chaibi","year":"2015","unstructured":"Chaibi A, Saltyte Benth J, Bjorn Russell M. Validation of Placebo in a Manual Therapy Randomized Controlled Trial. Sci Rep. 2015;5:11774. https:\/\/doi.org\/10.1038\/srep11774","journal-title":"Sci Rep"},{"issue":"1","key":"541_CR33","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/0304-3959(87)90089-3","volume":"30","author":"AA Fischer","year":"1987","unstructured":"Fischer AA. Pressure algometry over normal muscles. Standard values, validity and reproducibility of pressure threshold. Pain. 1987;30(1):115\u201326. https:\/\/doi.org\/10.1016\/0304-3959(87)90089-3","journal-title":"Pain"},{"key":"541_CR34","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.jbmt.2021.06.020","volume":"28","author":"PM Pena Junior","year":"2021","unstructured":"Pena Junior PM, de Sa Ferreira A, Telles G, Lemos T, Calazans Nogueira LA. Concurrent validation of the centre of pressure displacement analyzed by baropodometry in patients with chronic non-specific low back pain during functional tasks. J Bodyw Mov Ther. 2021;28:489\u201395. https:\/\/doi.org\/10.1016\/j.jbmt.2021.06.020","journal-title":"J Bodyw Mov Ther"},{"issue":"4","key":"541_CR35","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.gaitpost.2010.09.012","volume":"32","author":"A Ruhe","year":"2010","unstructured":"Ruhe A, Fejer R, Walker B. The test-retest reliability of centre of pressure measures in bipedal static task conditions\u2013a systematic review of the literature. Gait Posture. 2010;32(4):436\u201345. https:\/\/doi.org\/10.1016\/j.gaitpost.2010.09.012","journal-title":"Gait Posture"},{"issue":"Suppl 11","key":"541_CR36","doi-asserted-by":"publisher","first-page":"S240","DOI":"10.1002\/acr.20543","volume":"63","author":"GA Hawker","year":"2011","unstructured":"Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), short-form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), short Form-36 Bodily Pain Scale (SF-36 BPS), and measure of intermittent and constant Osteoarthritis Pain (ICOAP). Arthritis Care Res (Hoboken). 2011;63(Suppl 11):S240\u201352. https:\/\/doi.org\/10.1002\/acr.20543","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"1","key":"541_CR37","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.sjpain.2015.05.004","volume":"9","author":"R Waller","year":"2015","unstructured":"Waller R, Straker L, O\u2019Sullivan P, Sterling M, Smith A. Reliability of pressure pain threshold testing in healthy pain free young adults. Scand J Pain. 2015;9(1):38\u201341. https:\/\/doi.org\/10.1016\/j.sjpain.2015.05.004","journal-title":"Scand J Pain"},{"key":"541_CR38","doi-asserted-by":"publisher","unstructured":"Waller R, Straker L, O\u2019Sullivan P, Sterling M, Smith A. Corrigendum to \u2018Reliability of pressure pain threshold testing in healthy pain free young adults\u2019 [Scand. J. Pain 9 (2015) 38\u201341]. Scand J Pain. 2016;13(17). https:\/\/doi.org\/10.1016\/j.sjpain.2016.06.008","DOI":"10.1016\/j.sjpain.2016.06.008"},{"key":"541_CR39","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12998-018-0226-7","volume":"27","author":"SL Aspinall","year":"2019","unstructured":"Aspinall SL, Leboeuf-Yde C, Etherington SJ, Walker BF. Manipulation-induced hypoalgesia in musculoskeletal pain populations: a systematic critical review and meta-analysis. Chiropr Man Th. 2019;27:7. https:\/\/doi.org\/10.1186\/s12998-018-0226-7","journal-title":"Chiropr Man Th"},{"key":"541_CR40","doi-asserted-by":"publisher","unstructured":"Jung A, Adamczyk WM, Ahmed A, van der Schalk L, Poesl M, Luedtke K, et al. No sufficient evidence for an Immediate Hypoalgesic Effect of spinal manual therapy on pressure Pain Thresholds in Asymptomatic and Chronic Pain populations: a systematic review and Meta-analysis. Phys Ther. 2023;103(3). https:\/\/doi.org\/10.1093\/ptj\/pzad003","DOI":"10.1093\/ptj\/pzad003"},{"issue":"1","key":"541_CR41","doi-asserted-by":"publisher","first-page":"14615","DOI":"10.1038\/s41598-020-71557-y","volume":"10","author":"CG Nim","year":"2020","unstructured":"Nim CG, Kawchuk GN, Schiottz-Christensen B, O\u2019Neill S. The effect on clinical outcomes when targeting spinal manipulation at stiffness or pain sensitivity: a randomized trial. Sci Rep. 2020;10(1):14615. https:\/\/doi.org\/10.1038\/s41598-020-71557-y","journal-title":"Sci Rep"},{"key":"541_CR42","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.2222","author":"T Saueressig","year":"2023","unstructured":"Saueressig T, Owen PJ, Pedder H, Tagliaferri S, Kaczorowski S, Altrichter A, et al. The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: a systematic review and meta-analysis of randomized controlled trials. Eur J Pain. 2023. https:\/\/doi.org\/10.1002\/ejp.2222","journal-title":"Eur J Pain"},{"key":"541_CR43","doi-asserted-by":"publisher","first-page":"941","DOI":"10.2147\/JPR.S129313","volume":"10","author":"F Zangrando","year":"2017","unstructured":"Zangrando F, Piccinini G, Tagliolini C, Marsilli G, Iosa M, Vulpiani MC, et al. The efficacy of a preparatory phase of a touch-based approach in treating chronic low back pain: a randomized controlled trial. J Pain Res. 2017;10:941\u20139. https:\/\/doi.org\/10.2147\/JPR.S129313","journal-title":"J Pain Res"},{"issue":"3","key":"541_CR44","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1515\/sjpain-2019-0018","volume":"19","author":"J Setchell","year":"2019","unstructured":"Setchell J, Costa N, Ferreira M, Hodges PW. What decreases low back pain? A qualitative study of patient perspectives. Scand J Pain. 2019;19(3):597\u2013603. https:\/\/doi.org\/10.1515\/sjpain-2019-0018","journal-title":"Scand J Pain"},{"issue":"12","key":"541_CR45","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1016\/j.jclinepi.2013.02.018","volume":"66","author":"ML Ferreira","year":"2013","unstructured":"Ferreira ML, Herbert RD, Ferreira PH, Latimer J, Ostelo RW, Grotle M, et al. The smallest worthwhile effect of nonsteroidal anti-inflammatory drugs and physiotherapy for chronic low back pain: a benefit-harm trade-off study. J Clin Epidemiol. 2013;66(12):1397\u2013404. https:\/\/doi.org\/10.1016\/j.jclinepi.2013.02.018","journal-title":"J Clin Epidemiol"},{"issue":"21 Suppl","key":"541_CR46","doi-asserted-by":"publisher","first-page":"S54","DOI":"10.1097\/BRS.0b013e31822ef74d","volume":"36","author":"JR Chapman","year":"2011","unstructured":"Chapman JR, Norvell DC, Hermsmeyer JT, Bransford RJ, DeVine J, McGirt MJ, et al. Evaluating common outcomes for measuring treatment success for chronic low back pain. Spine (Phila Pa 1976). 2011;36(21 Suppl):S54\u201368. https:\/\/doi.org\/10.1097\/BRS.0b013e31822ef74d","journal-title":"Spine (Phila Pa 1976)"}],"container-title":["Chiropractic &amp; Manual Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12998-024-00541-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12998-024-00541-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12998-024-00541-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T16:03:48Z","timestamp":1717171428000},"score":1,"resource":{"primary":{"URL":"https:\/\/chiromt.biomedcentral.com\/articles\/10.1186\/s12998-024-00541-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,31]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["541"],"URL":"https:\/\/doi.org\/10.1186\/s12998-024-00541-4","relation":{},"ISSN":["2045-709X"],"issn-type":[{"value":"2045-709X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,31]]},"assertion":[{"value":"4 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethics approval and consent to participate. The study was approved by the Research Ethics Committee of the Midwestern Parana State University (UNICENTRO) and was conducted in accordance with the Declaration of Helsinki for research in humans (CAAE: 31299020.0.0000.0106). All included participants signed the written Informed Consent Form before the experimental procedures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The trial was registered at the Brazilian Registry of Clinical Trials \u2013 RBR-3ksq2c (WHO U1111-1252-3077).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Trial registration"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors state no conflicts of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"20"}}