{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:59:49Z","timestamp":1782885589643,"version":"3.54.5"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diagn Pathol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Primary cardiac lymphomas are extremely rare entities (&lt;\u20092% of cardiac tumours) and the most frequent histologic type is diffuse large B-cell lymphoma (DLBCL). Fibrin-associated DLBCL (FA-DLBCL) is a very unusual form of DLBCL associated with chronic inflammation, and only case reports and small series have been described. In the heart, it usually occurs in the context of a cardiac myxoma or cardiac prostheses and it is not bulk forming. These lymphomas frequently present with non-germinal center phenotype and are associated with Epstein-Barr virus (EBV) type III latency.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Case presentation<\/jats:title>\n<jats:p>We describe a case of FA-DLBCL arising in a cardiac myxoma, with plasmacytic differentiation and type I EBV latency.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Although they are very rare, FA-DLBCLs should be known for their diagnostic difficulty, due to its unspecified clinical manifestations, and for their more favourable prognosis, sometimes even without additional treatment after surgical resection.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s13000-020-01034-7","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T09:03:13Z","timestamp":1600938193000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Fibrin-associated diffuse large B-cell lymphoma with plasmacytic differentiation: case report and literature review"],"prefix":"10.1186","volume":"15","author":[{"given":"Esther Moreno","family":"Moreno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Ferrer-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor Pian","family":"Arias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene Garc\u00eda","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Garc\u00eda-Cos\u00edo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"issue":"1","key":"1034_CR1","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.carpath.2014.08.007","volume":"24","author":"C Aguilar","year":"2015","unstructured":"Aguilar C, Beltran B, Qui\u00f1ones P, Carbajal T, Vilcapaza J, Yabar A, et al. 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Diffuse large B-cell lymphoma associated with chronic inflammation as an incidental finding and new clinical scenarios. Mod Pathol. 2010;23(4):493\u2013501. https:\/\/doi.org\/10.1038\/modpathol.2009.168.","journal-title":"Mod Pathol"},{"issue":"3","key":"1034_CR4","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1097\/PAS.0000000000000775","volume":"41","author":"DF Boyer","year":"2017","unstructured":"Boyer DF, McKelvie PA, de Leval L, Edlefsen KL, Ko YH, Aberman ZA, et al. Fibrin-associated EBV-positive large B-cell lymphoma: an indolent neoplasm with features distinct from diffuse large B-cell lymphoma associated with chronic inflammation. 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Leuk Lymphoma. 2015;56(2):505\u20137. https:\/\/doi.org\/10.3109\/10428194.2014.919632.","journal-title":"Leuk Lymphoma"},{"issue":"8","key":"1034_CR7","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1182\/blood-2018-12-889337","volume":"133","author":"S Garces","year":"2019","unstructured":"Garces S, Sriganeshan V. Fibrin-associated diffuse large B-cell lymphoma confined to a cardiac myxoma. Blood. 2019;133(8):882. https:\/\/doi.org\/10.1182\/blood-2018-12-889337.","journal-title":"Blood."},{"issue":"3","key":"1034_CR8","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/bjh.15786","volume":"185","author":"M Zanelli","year":"2019","unstructured":"Zanelli M, Zizzo M, De Marco L, Bisagni A, Ascani S. Fibrin-associated diffuse large B-cell lymphoma. 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